Lactone derivatives produced by a Phaeoacremonium sp., an endophytic fungus from Senna spectabilis

• Autor(a) principal: Silva, Geraldo H.
• Data de Publicação: 2017
• Outros Autores: Zeraik, Maria L., Oliveira, Camila M. de, Teles, Helder L., Trevisan, Henrique C., Pfenning, Ludwig H., Nicolli, Camila P., Young, Maria C. M., Mascarenhas, Yvonne P., Abreu, Lucas M., Saraiva, Amanda C., Medeiros, Alexandra I., Bolzani, Vanderlan da S., Araujo, Angela R.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: LOCUS Repositório Institucional da UFV
• Texto Completo: https://doi.org/10.1021/acs.jnatprod.5b00828; http://www.locus.ufv.br/handle/123456789/19907
• topic: Phaeoacremonium sp.; Senna spectabilis

Three new isoaigialones, A, B, and C (1–3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis.