Impact of a chromosome X STR Decaplex in deficiency paternity cases

Detalhes bibliográficos
Autor(a) principal: Trindade Filho, Aluisio
Data de Publicação: 2013
Outros Autores: Ferreira, Samuel, Oliveira, Silviene Fabiana de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio.unb.br/handle/10482/28964
https://dx.doi.org/10.1590/S1415-47572013000400008
Resumo: Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested.
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spelling Impact of a chromosome X STR Decaplex in deficiency paternity casesGenética forensePaternidadeDeficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested.Sociedade Brasileira de Genética2017-12-07T05:03:45Z2017-12-07T05:03:45Z2013info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfTRINDADE FILHO, Aluisio; FERREIRA, Samuel; OLIVEIRA, Silviene Fabiana de. Impact of a chromosome X STR Decaplex in deficiency paternity cases. Genetics and Molecular Biology, São Paulo, v. 36, n. 4, p. 507-510, 2013. DOI: https://doi.org/10.1590/S1415-47572013000400008. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020.http://repositorio.unb.br/handle/10482/28964https://dx.doi.org/10.1590/S1415-47572013000400008Genetics and Molecular Biology - Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (CC BY NC 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020.info:eu-repo/semantics/openAccessTrindade Filho, AluisioFerreira, SamuelOliveira, Silviene Fabiana deengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-05-24T23:08:59Zoai:repositorio.unb.br:10482/28964Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-05-24T23:08:59Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Impact of a chromosome X STR Decaplex in deficiency paternity cases
title Impact of a chromosome X STR Decaplex in deficiency paternity cases
spellingShingle Impact of a chromosome X STR Decaplex in deficiency paternity cases
Trindade Filho, Aluisio
Genética forense
Paternidade
title_short Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_full Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_fullStr Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_full_unstemmed Impact of a chromosome X STR Decaplex in deficiency paternity cases
title_sort Impact of a chromosome X STR Decaplex in deficiency paternity cases
author Trindade Filho, Aluisio
author_facet Trindade Filho, Aluisio
Ferreira, Samuel
Oliveira, Silviene Fabiana de
author_role author
author2 Ferreira, Samuel
Oliveira, Silviene Fabiana de
author2_role author
author
dc.contributor.author.fl_str_mv Trindade Filho, Aluisio
Ferreira, Samuel
Oliveira, Silviene Fabiana de
dc.subject.por.fl_str_mv Genética forense
Paternidade
topic Genética forense
Paternidade
description Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested.
publishDate 2013
dc.date.none.fl_str_mv 2013
2017-12-07T05:03:45Z
2017-12-07T05:03:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv TRINDADE FILHO, Aluisio; FERREIRA, Samuel; OLIVEIRA, Silviene Fabiana de. Impact of a chromosome X STR Decaplex in deficiency paternity cases. Genetics and Molecular Biology, São Paulo, v. 36, n. 4, p. 507-510, 2013. DOI: https://doi.org/10.1590/S1415-47572013000400008. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020.
http://repositorio.unb.br/handle/10482/28964
https://dx.doi.org/10.1590/S1415-47572013000400008
identifier_str_mv TRINDADE FILHO, Aluisio; FERREIRA, Samuel; OLIVEIRA, Silviene Fabiana de. Impact of a chromosome X STR Decaplex in deficiency paternity cases. Genetics and Molecular Biology, São Paulo, v. 36, n. 4, p. 507-510, 2013. DOI: https://doi.org/10.1590/S1415-47572013000400008. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020.
url http://repositorio.unb.br/handle/10482/28964
https://dx.doi.org/10.1590/S1415-47572013000400008
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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