The frequency-amplitude gradient in the sleep EEG of children and its diagnostic significance

• Autor(a) principal: Aucélio, Carlos Nogueira
• Data de Publicação: 2007
• Outros Autores: Niedermeyer, Ernst, Melo, Áurea Nogueira de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UnB
• Texto Completo: http://repositorio.unb.br/handle/10482/26828; https://dx.doi.org/10.1590/S0004-282X2007000200004
• topic: pediatric sleep EEG; frequency-amplitude gradient; posterior slow waves; neurological disorder; EEG pediátrico em sono; gradiente de freqüência-amplitude; ondas lentas posteriores; comprometimento neurológico

OBJECTIVE: 1014 EEGs of children in the 3-months to 12-years age group were obtained during sleep with the purpose of assessing the frequency and amplitude gradient (FAG) its absence thought to be an indicator of neurological disorder. METHOD: FAG findings were divided into present/absent. The neurological findings were classified according to the presence (abnormal neurological finding-ANF) or absence (normal neurological finding-NNF) of neurological disorder. The association and significance between FAG and neurological findings was determined by prevalence ration (PR) and chi-square test (chi2). RESULTS: FAG showed a characteristic distributions of voltage output during non-REM sleep, stage II, in the 3-months to 5-years age group with NNF. The PR and the chi2 test demonstrated a strong association between FAG absent and ANF. CONCLUSION: FAG is an age-dependent EEG sleep parameter and absence of FAG in the 3-months to 5-years age group is highly suggestive of neurological disorder.