Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital

• Autor(a) principal: Saavedra, Pamela Alejandra
• Data de Publicação: 2016
• Outros Autores: Meiners, Micheline Marie Milward de Azevedo, Lopes, Luciane Cruz, Silva, Emília Vitória da, Silva, Dayde Lane Mendonça da, Noronha, Elza Ferreira, Toledo, Maria Inês de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UnB
• Texto Completo: http://repositorio.unb.br/handle/10482/30035; http://dx.doi.org/10.1590/0037-8682-0238-2016
• topic: Medicamentos - efeitos colaterais; Medicamentos - controle de qualidade; Hospitais

Introduction: despite the therapeutic benefits of drugs, adverse drug reactions (ADRs) occur. Method: We assessed a series of suspected ADRs identified from notifications and intensive monitoring of inpatients from March 2013 to March 2014. Results: skin reactions predominated (31%). Systemic anti-infective agents were implicated in 16 (72%) reactions. Fifteen (68%) ADRs were classified as possible. The implicated drug was not correctly identified by the healthcare team in 12 cases. Conclusions: some reactions were not correctly attributed to the causative drug(s), suggesting that the use of a validated evaluation method can promote successful identification of causal links between ADRs and drugs.