Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil

Detalhes bibliográficos
Autor(a) principal: Vernal, Sebastian
Data de Publicação: 2019
Outros Autores: Bueno Filho, Roberto, Gomes, Ciro Martins, Roselino, Ana Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: https://repositorio.unb.br/handle/10482/36249
https://doi.org/10.1590/0037-8682-0172-2018
http://orcid.org/0000-0002-2709-1825
Resumo: INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce. METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases. RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases. CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.
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spelling Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern BrazilLeishmanioseHanseníaseLeishmaniose cutâneaINTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce. METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases. RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases. CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.Faculdade de Medicina (FMD)Sociedade Brasileira de Medicina Tropical - SBMT2020-01-24T10:30:00Z2020-01-24T10:30:00Z2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfVERNAL, Sebastian et al. Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: a case series in Southeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180172, 2019. DOI: https://doi.org/10.1590/0037-8682-0172-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100633. Acesso em: 23 jan. 2020.https://repositorio.unb.br/handle/10482/36249https://doi.org/10.1590/0037-8682-0172-2018http://orcid.org/0000-0002-2709-1825Vernal, SebastianBueno Filho, RobertoGomes, Ciro MartinsRoselino, Ana Mariainfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-22T18:59:58Zoai:repositorio.unb.br:10482/36249Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-22T18:59:58Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
title Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
spellingShingle Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
Vernal, Sebastian
Leishmaniose
Hanseníase
Leishmaniose cutânea
title_short Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
title_full Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
title_fullStr Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
title_full_unstemmed Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
title_sort Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
author Vernal, Sebastian
author_facet Vernal, Sebastian
Bueno Filho, Roberto
Gomes, Ciro Martins
Roselino, Ana Maria
author_role author
author2 Bueno Filho, Roberto
Gomes, Ciro Martins
Roselino, Ana Maria
author2_role author
author
author
dc.contributor.author.fl_str_mv Vernal, Sebastian
Bueno Filho, Roberto
Gomes, Ciro Martins
Roselino, Ana Maria
dc.subject.por.fl_str_mv Leishmaniose
Hanseníase
Leishmaniose cutânea
topic Leishmaniose
Hanseníase
Leishmaniose cutânea
description INTRODUCTION: American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce. METHODS: We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases. RESULTS: Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases. CONCLUSIONS: The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.
publishDate 2019
dc.date.none.fl_str_mv 2019
2020-01-24T10:30:00Z
2020-01-24T10:30:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv VERNAL, Sebastian et al. Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: a case series in Southeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180172, 2019. DOI: https://doi.org/10.1590/0037-8682-0172-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100633. Acesso em: 23 jan. 2020.
https://repositorio.unb.br/handle/10482/36249
https://doi.org/10.1590/0037-8682-0172-2018
http://orcid.org/0000-0002-2709-1825
identifier_str_mv VERNAL, Sebastian et al. Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: a case series in Southeastern Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180172, 2019. DOI: https://doi.org/10.1590/0037-8682-0172-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100633. Acesso em: 23 jan. 2020.
url https://repositorio.unb.br/handle/10482/36249
https://doi.org/10.1590/0037-8682-0172-2018
http://orcid.org/0000-0002-2709-1825
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
_version_ 1814508221222617088

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