Complementary exams in the diagnosis of american tegumentary leishmaniasis
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UnB |
Texto Completo: | http://repositorio.unb.br/handle/10482/29295 https://dx.doi.org/10.1590/abd1806-4841.20142389 |
Resumo: | The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition. |
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Complementary exams in the diagnosis of american tegumentary leishmaniasisDermatologiaDiagnósticoLeishmaniose mucocutâneaBiologia molecularReação em cadeia de polimeraseSorologiaThe diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition.Faculdade de Medicina (FMD)Sociedade Brasileira de Dermatologia2017-12-07T05:07:32Z2017-12-07T05:07:32Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfGOMES, Ciro Martins et al. Complementary exams in the diagnosis of american tegumentary leishmaniasis. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 89, n. 5, p. 701-709, out. 2014. DOI: http://dx.doi.org/10.1590/abd1806-4841.20142389. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&nrm=iso. Acesso em: 08 dez. 2019.http://repositorio.unb.br/handle/10482/29295https://dx.doi.org/10.1590/abd1806-4841.20142389Anais Brasileiros de Dermatologia - (CC BY NC) - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&tlng=en. Acesso em: 08 dez. 2019.info:eu-repo/semantics/openAccessGomes, Ciro MartinsPaula, Natália Aparecida deMorais, Orlando Oliveira deSoares, Killarney AtaídeRoselino, Ana MariaSampaio, Raimunda Nonata Ribeiroengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-22T19:06:04Zoai:repositorio.unb.br:10482/29295Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-22T19:06:04Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.none.fl_str_mv |
Complementary exams in the diagnosis of american tegumentary leishmaniasis |
title |
Complementary exams in the diagnosis of american tegumentary leishmaniasis |
spellingShingle |
Complementary exams in the diagnosis of american tegumentary leishmaniasis Gomes, Ciro Martins Dermatologia Diagnóstico Leishmaniose mucocutânea Biologia molecular Reação em cadeia de polimerase Sorologia |
title_short |
Complementary exams in the diagnosis of american tegumentary leishmaniasis |
title_full |
Complementary exams in the diagnosis of american tegumentary leishmaniasis |
title_fullStr |
Complementary exams in the diagnosis of american tegumentary leishmaniasis |
title_full_unstemmed |
Complementary exams in the diagnosis of american tegumentary leishmaniasis |
title_sort |
Complementary exams in the diagnosis of american tegumentary leishmaniasis |
author |
Gomes, Ciro Martins |
author_facet |
Gomes, Ciro Martins Paula, Natália Aparecida de Morais, Orlando Oliveira de Soares, Killarney Ataíde Roselino, Ana Maria Sampaio, Raimunda Nonata Ribeiro |
author_role |
author |
author2 |
Paula, Natália Aparecida de Morais, Orlando Oliveira de Soares, Killarney Ataíde Roselino, Ana Maria Sampaio, Raimunda Nonata Ribeiro |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Gomes, Ciro Martins Paula, Natália Aparecida de Morais, Orlando Oliveira de Soares, Killarney Ataíde Roselino, Ana Maria Sampaio, Raimunda Nonata Ribeiro |
dc.subject.por.fl_str_mv |
Dermatologia Diagnóstico Leishmaniose mucocutânea Biologia molecular Reação em cadeia de polimerase Sorologia |
topic |
Dermatologia Diagnóstico Leishmaniose mucocutânea Biologia molecular Reação em cadeia de polimerase Sorologia |
description |
The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014 2017-12-07T05:07:32Z 2017-12-07T05:07:32Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
GOMES, Ciro Martins et al. Complementary exams in the diagnosis of american tegumentary leishmaniasis. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 89, n. 5, p. 701-709, out. 2014. DOI: http://dx.doi.org/10.1590/abd1806-4841.20142389. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&nrm=iso. Acesso em: 08 dez. 2019. http://repositorio.unb.br/handle/10482/29295 https://dx.doi.org/10.1590/abd1806-4841.20142389 |
identifier_str_mv |
GOMES, Ciro Martins et al. Complementary exams in the diagnosis of american tegumentary leishmaniasis. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 89, n. 5, p. 701-709, out. 2014. DOI: http://dx.doi.org/10.1590/abd1806-4841.20142389. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&nrm=iso. Acesso em: 08 dez. 2019. |
url |
http://repositorio.unb.br/handle/10482/29295 https://dx.doi.org/10.1590/abd1806-4841.20142389 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
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reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
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Universidade de Brasília (UnB) |
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UNB |
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Repositório Institucional da UnB |
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Repositório Institucional da UnB |
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Repositório Institucional da UnB - Universidade de Brasília (UnB) |
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repositorio@unb.br |
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