Complementary exams in the diagnosis of american tegumentary leishmaniasis

Detalhes bibliográficos
Autor(a) principal: Gomes, Ciro Martins
Data de Publicação: 2014
Outros Autores: Paula, Natália Aparecida de, Morais, Orlando Oliveira de, Soares, Killarney Ataíde, Roselino, Ana Maria, Sampaio, Raimunda Nonata Ribeiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio.unb.br/handle/10482/29295
https://dx.doi.org/10.1590/abd1806-4841.20142389
Resumo: The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition.
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spelling Complementary exams in the diagnosis of american tegumentary leishmaniasisDermatologiaDiagnósticoLeishmaniose mucocutâneaBiologia molecularReação em cadeia de polimeraseSorologiaThe diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition.Faculdade de Medicina (FMD)Sociedade Brasileira de Dermatologia2017-12-07T05:07:32Z2017-12-07T05:07:32Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfGOMES, Ciro Martins et al. Complementary exams in the diagnosis of american tegumentary leishmaniasis. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 89, n. 5, p. 701-709, out. 2014. DOI: http://dx.doi.org/10.1590/abd1806-4841.20142389. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&nrm=iso. Acesso em: 08 dez. 2019.http://repositorio.unb.br/handle/10482/29295https://dx.doi.org/10.1590/abd1806-4841.20142389Anais Brasileiros de Dermatologia - (CC BY NC) - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&tlng=en. Acesso em: 08 dez. 2019.info:eu-repo/semantics/openAccessGomes, Ciro MartinsPaula, Natália Aparecida deMorais, Orlando Oliveira deSoares, Killarney AtaídeRoselino, Ana MariaSampaio, Raimunda Nonata Ribeiroengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-22T19:06:04Zoai:repositorio.unb.br:10482/29295Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-22T19:06:04Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Complementary exams in the diagnosis of american tegumentary leishmaniasis
title Complementary exams in the diagnosis of american tegumentary leishmaniasis
spellingShingle Complementary exams in the diagnosis of american tegumentary leishmaniasis
Gomes, Ciro Martins
Dermatologia
Diagnóstico
Leishmaniose mucocutânea
Biologia molecular
Reação em cadeia de polimerase
Sorologia
title_short Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_full Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_fullStr Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_full_unstemmed Complementary exams in the diagnosis of american tegumentary leishmaniasis
title_sort Complementary exams in the diagnosis of american tegumentary leishmaniasis
author Gomes, Ciro Martins
author_facet Gomes, Ciro Martins
Paula, Natália Aparecida de
Morais, Orlando Oliveira de
Soares, Killarney Ataíde
Roselino, Ana Maria
Sampaio, Raimunda Nonata Ribeiro
author_role author
author2 Paula, Natália Aparecida de
Morais, Orlando Oliveira de
Soares, Killarney Ataíde
Roselino, Ana Maria
Sampaio, Raimunda Nonata Ribeiro
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Gomes, Ciro Martins
Paula, Natália Aparecida de
Morais, Orlando Oliveira de
Soares, Killarney Ataíde
Roselino, Ana Maria
Sampaio, Raimunda Nonata Ribeiro
dc.subject.por.fl_str_mv Dermatologia
Diagnóstico
Leishmaniose mucocutânea
Biologia molecular
Reação em cadeia de polimerase
Sorologia
topic Dermatologia
Diagnóstico
Leishmaniose mucocutânea
Biologia molecular
Reação em cadeia de polimerase
Sorologia
description The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since the discovery of its etiologic agent, numerous diagnostic tests have been developed. None of the tests available today can be considered as the gold standard, since they do not add enough accuracy for the disease detection. Good epidemiological and clinical knowledge of the disease are fundamental precepts of the dermatology practice and precede the rational use of existing diagnostic tests. In this article we aim, through extensive literature review, to recall fundamental concepts of any diagnostic test. Subsequently, based on this information, we will weave important comments about the characteristics of existing diagnostic tests, including immunological tests such as Montenegro's skin test, serology and detection of parasites by direct examination, culture or histopathology. Finally we will discuss the new technologies and options for the diagnosis of Cutaneous Leishmaniasis. The molecular biology technique is considered a promising tool, promoting the rapid identification of the species involved. We also aim to educate dermatologists about a disease with high morbidity and assist in its difficult recognition.
publishDate 2014
dc.date.none.fl_str_mv 2014
2017-12-07T05:07:32Z
2017-12-07T05:07:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv GOMES, Ciro Martins et al. Complementary exams in the diagnosis of american tegumentary leishmaniasis. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 89, n. 5, p. 701-709, out. 2014. DOI: http://dx.doi.org/10.1590/abd1806-4841.20142389. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&nrm=iso. Acesso em: 08 dez. 2019.
http://repositorio.unb.br/handle/10482/29295
https://dx.doi.org/10.1590/abd1806-4841.20142389
identifier_str_mv GOMES, Ciro Martins et al. Complementary exams in the diagnosis of american tegumentary leishmaniasis. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 89, n. 5, p. 701-709, out. 2014. DOI: http://dx.doi.org/10.1590/abd1806-4841.20142389. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000500701&lng=en&nrm=iso. Acesso em: 08 dez. 2019.
url http://repositorio.unb.br/handle/10482/29295
https://dx.doi.org/10.1590/abd1806-4841.20142389
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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