Distribution of hepatitis C virus genotypes among blood donors from mid-west region of Brazil

• Autor(a) principal: Martins, Regina M.B.
• Data de Publicação: 2006
• Outros Autores: Teles, Sheila A., Freitas, Nara R., Motta-Castro, Ana R.C., Souto, Francisco J.D., Mussi, Aparecida, Amorim, Regina M.S., Martins, Cláudia R.F.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UnB
• Texto Completo: http://repositorio.unb.br/handle/10482/26594; https://dx.doi.org/10.1590/S0036-46652006000100012
• topic: Hepatite C; Genótipos; Doadores de sangue

In order to investigate the hepatitis C virus (HCV) genotypes in mid-west region of Brazil, 250 anti-HCV positive blood donors were studied. Among them, the anti-HCV serological status was confirmed in 205 (82%). HCV RNA was detected in 165 samples, which were genotyped. HCV types 1, 2 and 3 were found in 67.9%, 3% and 29.1% of the donors, respectively. In Goiás state, subtype 1a (50%) was the most prevalent, followed by subtypes 3a (30.9%) and 1b (16.7%). In Mato Grosso state, subtype 1a was also predominant (41%), followed by subtypes 1b (29.5%) and 3a (25%). In Mato Grosso do Sul state, subtypes 1a and 1b were detected equally (36.8%), followed by 3a (21.1%). Subtype 2b was rare (2.4%, 4.5% and 5.3%, respectively). In Distrito Federal, subtype 3a (39%) was more frequent than 1a (31.7%) and the remaining (29.3%) belonged to subtype 1b.