Clinical application of Chamomilla recutita in phlebitis: dose response curve study

Detalhes bibliográficos
Autor(a) principal: Reis, Paula Elaine Diniz dos
Data de Publicação: 2011
Outros Autores: Carvalho, Emilia Campos de, Bueno, Paula Carolina Pires, Bastos, Jairo Kenupp
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio.unb.br/handle/10482/28107
https://dx.doi.org/10.1590/S0104-11692011000100002
Resumo: This experimental and dose-response curve study aimed to carry out the quality control of the Chamomilla recutita sample, as well as to estimate the ideal dose, for anti-inflammatory effect, of the extract of its capitula, in patients with phlebitis due to peripheral intravenous infusion of antineoplastic chemotherapy and to evaluate the toxicity of this extract in human beings. The therapeutic efficacy, concerning the anti-inflammatory potential, of different doses of Chamomilla recutita extract were analyzed and compared in 25 patients. The time of regression of phlebitis was shorter for groups with 2.5% concentration (mean=29.2h, standard deviation = 8.98) and 5% concentration (mean = 38.8h, standard deviation = 17.47). Local toxicity was almost not observed. This research contributes to the innovation of the nursing clinical practice, since it suggests an alternative for the treatment of phlebitis through the clinical use of phytotherapeutic drugs.
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spelling Clinical application of Chamomilla recutita in phlebitis: dose response curve studyAplicação clínica da Chamomilla recutita em flebites: estudo de curva dose-respostaAplicación clínica de la Chamomilla recutita en flebitis: estudio de la curva dosis-respuestaCamomilaFlebiteRelação dose-resposta a drogaThis experimental and dose-response curve study aimed to carry out the quality control of the Chamomilla recutita sample, as well as to estimate the ideal dose, for anti-inflammatory effect, of the extract of its capitula, in patients with phlebitis due to peripheral intravenous infusion of antineoplastic chemotherapy and to evaluate the toxicity of this extract in human beings. The therapeutic efficacy, concerning the anti-inflammatory potential, of different doses of Chamomilla recutita extract were analyzed and compared in 25 patients. The time of regression of phlebitis was shorter for groups with 2.5% concentration (mean=29.2h, standard deviation = 8.98) and 5% concentration (mean = 38.8h, standard deviation = 17.47). Local toxicity was almost not observed. This research contributes to the innovation of the nursing clinical practice, since it suggests an alternative for the treatment of phlebitis through the clinical use of phytotherapeutic drugs.Neste estudo, buscou-se realizar o controle de qualidade da amostra de Chamomilla recutita, bem como estimar a dose ideal, para efeito anti-inflamatório, do infuso dos seus capítulos florais, em pacientes com flebite, decorrente de infusão intravenosa periférica de quimioterapia antineoplásica, e avaliar a toxicidade desse infuso em seres humanos. Trata-se de estudo experimental, do tipo curva dose-resposta, no qual foi analisada e comparada a eficácia terapêutica, quanto ao potencial anti-inflamatório, de diferentes doses do infuso da Chamomilla recutita, em 25 pacientes. O tempo de regressão da flebite foi menor para os grupos com concentração 2,5% (média=29,2h, desvio padrão=8,98) e 5% (média=38,8h, desvio padrão=17,47) e praticamente não se observou toxicidade local. Esta pesquisa contribui para a inovação da prática clínica em enfermagem, uma vez que sugere alternativa para o tratamento de flebites, por meio da utilização clínica de fitoterápicos.En este estudio, se buscó realizar el control de calidad de la muestra de Chamomilla recutita, así como estimar la dosis ideal, para efecto antiinflamatorio, de la infusión de sus inflorescencias, en pacientes con flebitis proveniente de introducción intravenosa periférica de quimioterapia antineoplásica y evaluar la toxicidad de esta infusión en los seres humanos. Se trata de estudio experimental, del tipo curva dosis-respuesta, en el cual fue analizada y comparada la eficacia terapéutica, en cuanto al potencial antiinflamatorio, de diferentes dosis de la infusión de la Chamomilla recutita en 25 pacientes. El tiempo de regresión de la flebitis fue menor para los grupos con concentración 2,5% (promedio = 29,2h, desviación estándar = 8,98) y 5% (promedio = 38,8h, desviación estándar = 17,47) y prácticamente no se observó toxicidad local. Esta investigación contribuye para la innovación de la práctica clínica en enfermería, una vez que sugiere una alternativa para el tratamiento de la flebitis por medio de la utilización clínica de fitoterapéuticos.Em processamentoEscola de Enfermagem de Ribeirão Preto / Universidade de São Paulo2017-12-07T04:56:38Z2017-12-07T04:56:38Z2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfRev. Latino-Am. Enfermagem,v.19,n.1,p.03-10,2011http://repositorio.unb.br/handle/10482/28107https://dx.doi.org/10.1590/S0104-11692011000100002Reis, Paula Elaine Diniz dosCarvalho, Emilia Campos deBueno, Paula Carolina PiresBastos, Jairo Kenuppinfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2024-08-27T21:13:08Zoai:repositorio.unb.br:10482/28107Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2024-08-27T21:13:08Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Clinical application of Chamomilla recutita in phlebitis: dose response curve study
Aplicação clínica da Chamomilla recutita em flebites: estudo de curva dose-resposta
Aplicación clínica de la Chamomilla recutita en flebitis: estudio de la curva dosis-respuesta
title Clinical application of Chamomilla recutita in phlebitis: dose response curve study
spellingShingle Clinical application of Chamomilla recutita in phlebitis: dose response curve study
Reis, Paula Elaine Diniz dos
Camomila
Flebite
Relação dose-resposta a droga
title_short Clinical application of Chamomilla recutita in phlebitis: dose response curve study
title_full Clinical application of Chamomilla recutita in phlebitis: dose response curve study
title_fullStr Clinical application of Chamomilla recutita in phlebitis: dose response curve study
title_full_unstemmed Clinical application of Chamomilla recutita in phlebitis: dose response curve study
title_sort Clinical application of Chamomilla recutita in phlebitis: dose response curve study
author Reis, Paula Elaine Diniz dos
author_facet Reis, Paula Elaine Diniz dos
Carvalho, Emilia Campos de
Bueno, Paula Carolina Pires
Bastos, Jairo Kenupp
author_role author
author2 Carvalho, Emilia Campos de
Bueno, Paula Carolina Pires
Bastos, Jairo Kenupp
author2_role author
author
author
dc.contributor.author.fl_str_mv Reis, Paula Elaine Diniz dos
Carvalho, Emilia Campos de
Bueno, Paula Carolina Pires
Bastos, Jairo Kenupp
dc.subject.por.fl_str_mv Camomila
Flebite
Relação dose-resposta a droga
topic Camomila
Flebite
Relação dose-resposta a droga
description This experimental and dose-response curve study aimed to carry out the quality control of the Chamomilla recutita sample, as well as to estimate the ideal dose, for anti-inflammatory effect, of the extract of its capitula, in patients with phlebitis due to peripheral intravenous infusion of antineoplastic chemotherapy and to evaluate the toxicity of this extract in human beings. The therapeutic efficacy, concerning the anti-inflammatory potential, of different doses of Chamomilla recutita extract were analyzed and compared in 25 patients. The time of regression of phlebitis was shorter for groups with 2.5% concentration (mean=29.2h, standard deviation = 8.98) and 5% concentration (mean = 38.8h, standard deviation = 17.47). Local toxicity was almost not observed. This research contributes to the innovation of the nursing clinical practice, since it suggests an alternative for the treatment of phlebitis through the clinical use of phytotherapeutic drugs.
publishDate 2011
dc.date.none.fl_str_mv 2011
2017-12-07T04:56:38Z
2017-12-07T04:56:38Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Rev. Latino-Am. Enfermagem,v.19,n.1,p.03-10,2011
http://repositorio.unb.br/handle/10482/28107
https://dx.doi.org/10.1590/S0104-11692011000100002
identifier_str_mv Rev. Latino-Am. Enfermagem,v.19,n.1,p.03-10,2011
url http://repositorio.unb.br/handle/10482/28107
https://dx.doi.org/10.1590/S0104-11692011000100002
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo
publisher.none.fl_str_mv Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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