Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Odontologia da UNESP |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772019000100442 |
Resumo: | Abstract Introduction Candida albicans is the yeast most commonly affecting the oral cavity, sometimes causing infection. However, several factors may be associated with the onset of candidiasis, which may be related not only to the hygiene and health of individuals, but also to the pathogenicity of these microorganisms. Objective To evaluate the virulence factors of Candida yeasts isolated from the oral mucosa of elderly people living in the “Comunidade Lago do Limão”, municipality of Iranduba, Amazonas state, Brazil. Material and method Testes were performed to assess the production of urease, proteinase, phospholipase and hemolysin. Statistical analysis used the Fisher's exact test and the Chi-squared test. Result Prevalence of non-albicans species was observed. As for virulence factors, all isolates were negative ureases, and there was prevalence of very strong proteinase production, whereas most isolates did not produce this enzyme in the phospholipase test. All yeasts analyzed presented hemolysin production, with grade IV hemolysis as the most prevalent. There was no statistically significant difference between the virulence of isolates from the oral cavity and the prostheses of the elderly analyzed. Conclusion Several virulence factors may present with high intensity in the presence of oral microbiota changes. In addition, non-albicans species present number of virulence factors similar to that of C. albicans, with high pathogenicity. This study allows a better analysis of candidiasis prevention strategies aiming to promote improvement in the health and quality of life for the elderly. |
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Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, BrazilCandidaoral mucosadental prosthesisvirulenceAbstract Introduction Candida albicans is the yeast most commonly affecting the oral cavity, sometimes causing infection. However, several factors may be associated with the onset of candidiasis, which may be related not only to the hygiene and health of individuals, but also to the pathogenicity of these microorganisms. Objective To evaluate the virulence factors of Candida yeasts isolated from the oral mucosa of elderly people living in the “Comunidade Lago do Limão”, municipality of Iranduba, Amazonas state, Brazil. Material and method Testes were performed to assess the production of urease, proteinase, phospholipase and hemolysin. Statistical analysis used the Fisher's exact test and the Chi-squared test. Result Prevalence of non-albicans species was observed. As for virulence factors, all isolates were negative ureases, and there was prevalence of very strong proteinase production, whereas most isolates did not produce this enzyme in the phospholipase test. All yeasts analyzed presented hemolysin production, with grade IV hemolysis as the most prevalent. There was no statistically significant difference between the virulence of isolates from the oral cavity and the prostheses of the elderly analyzed. Conclusion Several virulence factors may present with high intensity in the presence of oral microbiota changes. In addition, non-albicans species present number of virulence factors similar to that of C. albicans, with high pathogenicity. This study allows a better analysis of candidiasis prevention strategies aiming to promote improvement in the health and quality of life for the elderly.Universidade Estadual Paulista Júlio de Mesquita Filho2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772019000100442Revista de Odontologia da UNESP v.48 2019reponame:Revista de Odontologia da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1590/1807-2577.09419info:eu-repo/semantics/openAccessSILVA,Daniela Marinho daSOUZA,Thayana Cruz deALENCAR,Carol Falcão de CarvalhoSOUZA,Ingrid da Silva deBANDEIRA,Maria Fulgência Costa LimaFERNANDES,Ormezinda Celeste Cristoeng2020-01-23T00:00:00Zoai:scielo:S1807-25772019000100442Revistahttps://www.revodontolunesp.com.br/PUBhttps://old.scielo.br/oai/scielo-oai.php||adriana@foar.unesp.br1807-25770101-1774opendoar:2020-01-23T00:00Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil |
title |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil |
spellingShingle |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil SILVA,Daniela Marinho da Candida oral mucosa dental prosthesis virulence |
title_short |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil |
title_full |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil |
title_fullStr |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil |
title_full_unstemmed |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil |
title_sort |
Virulence factors of Candida species from the oral mucosa and prostheses of elderly people from a riverside community in the Amazon state, Brazil |
author |
SILVA,Daniela Marinho da |
author_facet |
SILVA,Daniela Marinho da SOUZA,Thayana Cruz de ALENCAR,Carol Falcão de Carvalho SOUZA,Ingrid da Silva de BANDEIRA,Maria Fulgência Costa Lima FERNANDES,Ormezinda Celeste Cristo |
author_role |
author |
author2 |
SOUZA,Thayana Cruz de ALENCAR,Carol Falcão de Carvalho SOUZA,Ingrid da Silva de BANDEIRA,Maria Fulgência Costa Lima FERNANDES,Ormezinda Celeste Cristo |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
SILVA,Daniela Marinho da SOUZA,Thayana Cruz de ALENCAR,Carol Falcão de Carvalho SOUZA,Ingrid da Silva de BANDEIRA,Maria Fulgência Costa Lima FERNANDES,Ormezinda Celeste Cristo |
dc.subject.por.fl_str_mv |
Candida oral mucosa dental prosthesis virulence |
topic |
Candida oral mucosa dental prosthesis virulence |
description |
Abstract Introduction Candida albicans is the yeast most commonly affecting the oral cavity, sometimes causing infection. However, several factors may be associated with the onset of candidiasis, which may be related not only to the hygiene and health of individuals, but also to the pathogenicity of these microorganisms. Objective To evaluate the virulence factors of Candida yeasts isolated from the oral mucosa of elderly people living in the “Comunidade Lago do Limão”, municipality of Iranduba, Amazonas state, Brazil. Material and method Testes were performed to assess the production of urease, proteinase, phospholipase and hemolysin. Statistical analysis used the Fisher's exact test and the Chi-squared test. Result Prevalence of non-albicans species was observed. As for virulence factors, all isolates were negative ureases, and there was prevalence of very strong proteinase production, whereas most isolates did not produce this enzyme in the phospholipase test. All yeasts analyzed presented hemolysin production, with grade IV hemolysis as the most prevalent. There was no statistically significant difference between the virulence of isolates from the oral cavity and the prostheses of the elderly analyzed. Conclusion Several virulence factors may present with high intensity in the presence of oral microbiota changes. In addition, non-albicans species present number of virulence factors similar to that of C. albicans, with high pathogenicity. This study allows a better analysis of candidiasis prevention strategies aiming to promote improvement in the health and quality of life for the elderly. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772019000100442 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772019000100442 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1807-2577.09419 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista Júlio de Mesquita Filho |
publisher.none.fl_str_mv |
Universidade Estadual Paulista Júlio de Mesquita Filho |
dc.source.none.fl_str_mv |
Revista de Odontologia da UNESP v.48 2019 reponame:Revista de Odontologia da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Revista de Odontologia da UNESP |
collection |
Revista de Odontologia da UNESP |
repository.name.fl_str_mv |
Revista de Odontologia da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
||adriana@foar.unesp.br |
_version_ |
1748958560915554304 |