Cytotoxicity and degree of conversion of methacrylate and silorane

Detalhes bibliográficos
Autor(a) principal: Silva, Virgínia Angélica
Data de Publicação: 2020
Outros Autores: Gontijo, Sávio Morato de Lacerda, Gatti , Alexandre, Poletto, Luiz Thadeu de Abreu, Alvim, Hugo Henriques
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian journal of oral sciences (Online)
Texto Completo: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8660656
Resumo: Composites have been proven to have a cytotoxiceffect on a variety of tissues and cells. Aim: The aim of thisstudy was to analyse the degree of conversion of resinsand its correlation with the cell viability in primary gingivalfibroblasts. Methods: Resin-based silorane (Filtek P90)and conventional methacrylate resins (Filtek Z100, FiltekZ250 and Filtek Z350XT) were used to evaluate cell viabilityand the degree of conversion. The resins were light-cured bya LED for 20 and 40 seconds. The degree of conversion wasanalysed by Fourier transform infrared spectroscopy. Cellularmetabolism was evaluated after 24 hours by the MTT assay(n = 6) using the storage solution of composite resin foreither 24 hours or 12 days. Variance analysis (ANOVA) witha Bonferroni correction (p < 0.05) was performed to comparethe groups. Results: The composite Filtek P90 showed ahigher degree of conversion when polymerised for 40 or20 seconds, while the composites Filtek Z100, Filtek Z250 andFiltek Z350XT showed similar degree of conversion. Only theFiltek Z100 resin was cytotoxic. Conclusion: We found nostatistically significant correlation between cell viability andthe degree of conversion.
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spelling Cytotoxicity and degree of conversion of methacrylate and siloraneComposite resinsCytotoxinsFibroblastsComposites have been proven to have a cytotoxiceffect on a variety of tissues and cells. Aim: The aim of thisstudy was to analyse the degree of conversion of resinsand its correlation with the cell viability in primary gingivalfibroblasts. Methods: Resin-based silorane (Filtek P90)and conventional methacrylate resins (Filtek Z100, FiltekZ250 and Filtek Z350XT) were used to evaluate cell viabilityand the degree of conversion. The resins were light-cured bya LED for 20 and 40 seconds. The degree of conversion wasanalysed by Fourier transform infrared spectroscopy. Cellularmetabolism was evaluated after 24 hours by the MTT assay(n = 6) using the storage solution of composite resin foreither 24 hours or 12 days. Variance analysis (ANOVA) witha Bonferroni correction (p < 0.05) was performed to comparethe groups. Results: The composite Filtek P90 showed ahigher degree of conversion when polymerised for 40 or20 seconds, while the composites Filtek Z100, Filtek Z250 andFiltek Z350XT showed similar degree of conversion. Only theFiltek Z100 resin was cytotoxic. Conclusion: We found nostatistically significant correlation between cell viability andthe degree of conversion.Universidade Estadual de Campinas2020-11-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/866065610.20396/bjos.v19i0.8660656Brazilian Journal of Oral Sciences; v. 19 (2020): Continuous Publication; e200656Brazilian Journal of Oral Sciences; Vol. 19 (2020): Continuous Publication; e2006561677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPenghttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8660656/23202Brazil; ContemporanyCopyright (c) 2020 Brazilian Journal of Oral Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Virgínia Angélica Gontijo, Sávio Morato de Lacerda Gatti , Alexandre Poletto, Luiz Thadeu de Abreu Alvim, Hugo Henriques 2021-02-08T13:06:05Zoai:ojs.periodicos.sbu.unicamp.br:article/8660656Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2021-02-08T13:06:05Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false
dc.title.none.fl_str_mv Cytotoxicity and degree of conversion of methacrylate and silorane
title Cytotoxicity and degree of conversion of methacrylate and silorane
spellingShingle Cytotoxicity and degree of conversion of methacrylate and silorane
Silva, Virgínia Angélica
Composite resins
Cytotoxins
Fibroblasts
title_short Cytotoxicity and degree of conversion of methacrylate and silorane
title_full Cytotoxicity and degree of conversion of methacrylate and silorane
title_fullStr Cytotoxicity and degree of conversion of methacrylate and silorane
title_full_unstemmed Cytotoxicity and degree of conversion of methacrylate and silorane
title_sort Cytotoxicity and degree of conversion of methacrylate and silorane
author Silva, Virgínia Angélica
author_facet Silva, Virgínia Angélica
Gontijo, Sávio Morato de Lacerda
Gatti , Alexandre
Poletto, Luiz Thadeu de Abreu
Alvim, Hugo Henriques
author_role author
author2 Gontijo, Sávio Morato de Lacerda
Gatti , Alexandre
Poletto, Luiz Thadeu de Abreu
Alvim, Hugo Henriques
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Virgínia Angélica
Gontijo, Sávio Morato de Lacerda
Gatti , Alexandre
Poletto, Luiz Thadeu de Abreu
Alvim, Hugo Henriques
dc.subject.por.fl_str_mv Composite resins
Cytotoxins
Fibroblasts
topic Composite resins
Cytotoxins
Fibroblasts
description Composites have been proven to have a cytotoxiceffect on a variety of tissues and cells. Aim: The aim of thisstudy was to analyse the degree of conversion of resinsand its correlation with the cell viability in primary gingivalfibroblasts. Methods: Resin-based silorane (Filtek P90)and conventional methacrylate resins (Filtek Z100, FiltekZ250 and Filtek Z350XT) were used to evaluate cell viabilityand the degree of conversion. The resins were light-cured bya LED for 20 and 40 seconds. The degree of conversion wasanalysed by Fourier transform infrared spectroscopy. Cellularmetabolism was evaluated after 24 hours by the MTT assay(n = 6) using the storage solution of composite resin foreither 24 hours or 12 days. Variance analysis (ANOVA) witha Bonferroni correction (p < 0.05) was performed to comparethe groups. Results: The composite Filtek P90 showed ahigher degree of conversion when polymerised for 40 or20 seconds, while the composites Filtek Z100, Filtek Z250 andFiltek Z350XT showed similar degree of conversion. Only theFiltek Z100 resin was cytotoxic. Conclusion: We found nostatistically significant correlation between cell viability andthe degree of conversion.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-04
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/other
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8660656
10.20396/bjos.v19i0.8660656
url https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8660656
identifier_str_mv 10.20396/bjos.v19i0.8660656
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8660656/23202
dc.rights.driver.fl_str_mv Copyright (c) 2020 Brazilian Journal of Oral Sciences
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Brazilian Journal of Oral Sciences
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv Brazil; Contemporany
dc.publisher.none.fl_str_mv Universidade Estadual de Campinas
publisher.none.fl_str_mv Universidade Estadual de Campinas
dc.source.none.fl_str_mv Brazilian Journal of Oral Sciences; v. 19 (2020): Continuous Publication; e200656
Brazilian Journal of Oral Sciences; Vol. 19 (2020): Continuous Publication; e200656
1677-3225
reponame:Brazilian journal of oral sciences (Online)
instname:Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
instname_str Universidade Estadual de Campinas (UNICAMP)
instacron_str UNICAMP
institution UNICAMP
reponame_str Brazilian journal of oral sciences (Online)
collection Brazilian journal of oral sciences (Online)
repository.name.fl_str_mv Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)
repository.mail.fl_str_mv brjorals@fop.unicamp.br||brjorals@fop.unicamp.br
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