Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report

Detalhes bibliográficos
Autor(a) principal: Osborne, Patrick Rocha
Data de Publicação: 2020
Outros Autores: Mendes, Bruno, Faverani, Leonardo Perez, Alexandre, Cleber Nunes, Jesus, Giorge Pessoa de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/9415
Resumo: Objective: to describe the clinical case of a patient with multiple myeloma, who developed maxillary osteonecrosis induced by anti-resorptive medication (bisphosphonate) submitted to a conservative and surgical therapeutic approach and subsequent prosthetic rehabilitation. Patients and methods: the case report is presented based on a simple review of the literature and clinical experience for the diagnosis, clinical staging of the lesion, carrying out the excision of the necrotic bone, debridement, lesion control and making a obturator prosthesis. Results: Despite the difficulty offered by the pathological condition and continuous use of medication, the treatment employed was successful, restoring health and providing a better quality of life to the patient, which allowed the obturation prosthesis to be made in the 8-month postoperative period. Conclusion: The result obtained emphasizes the importance of knowledge of the staging of the lesion for the application of the treatment protocol, in addition to recognizing patients at risk for the practice of prevention in dental treatments.
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spelling Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case reportOsteonecrosis maxilar inducida por medicación antirresortiva (bisfosfonatos) en un paciente con mieloma múltiple - Reporte de casoOsteonecrose Maxilar Induzida por medicamento anti-reabsortivo (Bisfosfonato) em Paciente Portador de Mieloma Múltiplo – Relato de casoOsteonecroseMaxilaOsteonecrose associada a bifosfonatos.OsteonecrosisMaxilarOsteonecrosis de los maxilares asociada a bifosfonatos.OsteonecroseMaxilaBiphosphonate- associated osteonecrosis of the jaw.Objective: to describe the clinical case of a patient with multiple myeloma, who developed maxillary osteonecrosis induced by anti-resorptive medication (bisphosphonate) submitted to a conservative and surgical therapeutic approach and subsequent prosthetic rehabilitation. Patients and methods: the case report is presented based on a simple review of the literature and clinical experience for the diagnosis, clinical staging of the lesion, carrying out the excision of the necrotic bone, debridement, lesion control and making a obturator prosthesis. Results: Despite the difficulty offered by the pathological condition and continuous use of medication, the treatment employed was successful, restoring health and providing a better quality of life to the patient, which allowed the obturation prosthesis to be made in the 8-month postoperative period. Conclusion: The result obtained emphasizes the importance of knowledge of the staging of the lesion for the application of the treatment protocol, in addition to recognizing patients at risk for the practice of prevention in dental treatments.Objetivo: describir el caso clínico de un paciente con mieloma múltiple, que desarrolló osteonecrosis maxilar inducida por medicación antirresortiva (bisfosfonatos) sometido a un abordaje terapéutico conservador y quirúrgico y posterior rehabilitación protésica. Pacientes y métodos: se presenta el caso clínico en base a una simple revisión de la literatura y experiencia clínica para el diagnóstico, estadificación clínica de la lesión, realización de la exéresis del hueso necrótico, desbridamiento, control de la lesión y realización de una prótesis de obturación. Resultados: A pesar de la dificultad que ofrecía la condición patológica y el uso continuado de la medicación, el tratamiento empleado fue exitoso, devolviendo la salud y proporcionando una mejor calidad de vida al paciente, lo que permitió realizar la prótesis de obturación en el postoperatorio de 8 meses. Conclusión: El resultado obtenido enfatiza la importancia del conocimiento de la estadificación de la lesión para la aplicación del protocolo de tratamiento, además de reconocer a los pacientes en riesgo para la práctica de la prevención en los tratamientos dentales.Objetivo: descrever o caso clínico de uma paciente portadora de mieloma múltiplo, a qual desenvolveu osteonecrose maxilar induzida por medicamento anti-reabsortivo (bisfosfonato) submetida à abordagem terapêutica conservadora e cirúrgica e posterior reabilitação protética. Pacientes e métodos: o relato do caso é apresentado com base em uma revisão simples da literatura e experiência clínica para o diagnóstico, estadiamento clínico da lesão, realização da exérese do osso necrótico, debridamento, controle da lesão e confecção de prótese obturadora. Resultados: Apesar da dificuldade oferecida pela condição patológica e uso contínuo da medicação, o tratamento empregado apresentou sucesso, restabelecendo a saúde e proporcionando maior qualidade de vida a paciente, o que permitiu a confecção da prótese obturadora no pós-operatório de 8 meses. Conclusão: O resultado obtido enfatiza a importância do conhecimento do estadiamento da lesão para aplicação do protocolo de tratamento, além de reconhecer os pacientes de risco para a prática da prevenção nos tratamentos odontológicos.Research, Society and Development2020-11-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/941510.33448/rsd-v9i11.9415Research, Society and Development; Vol. 9 No. 11; e1179119415Research, Society and Development; Vol. 9 Núm. 11; e1179119415Research, Society and Development; v. 9 n. 11; e11791194152525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/9415/8592Copyright (c) 2020 Patrick Rocha Osborne; Bruno Mendes; Leonardo Perez Faverani; Cleber Nunes Alexandre; Giorge Pessoa de Jesushttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOsborne, Patrick RochaMendes, BrunoFaverani, Leonardo PerezAlexandre, Cleber Nunes Jesus, Giorge Pessoa de 2020-12-10T23:37:57Zoai:ojs.pkp.sfu.ca:article/9415Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:31:42.248934Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
Osteonecrosis maxilar inducida por medicación antirresortiva (bisfosfonatos) en un paciente con mieloma múltiple - Reporte de caso
Osteonecrose Maxilar Induzida por medicamento anti-reabsortivo (Bisfosfonato) em Paciente Portador de Mieloma Múltiplo – Relato de caso
title Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
spellingShingle Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
Osborne, Patrick Rocha
Osteonecrose
Maxila
Osteonecrose associada a bifosfonatos.
Osteonecrosis
Maxilar
Osteonecrosis de los maxilares asociada a bifosfonatos.
Osteonecrose
Maxila
Biphosphonate- associated osteonecrosis of the jaw.
title_short Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
title_full Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
title_fullStr Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
title_full_unstemmed Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
title_sort Maxillary osteonecrosis induced by antiresorptive medication (bisphosphonate) in a patient with multiple myeloma - Case report
author Osborne, Patrick Rocha
author_facet Osborne, Patrick Rocha
Mendes, Bruno
Faverani, Leonardo Perez
Alexandre, Cleber Nunes
Jesus, Giorge Pessoa de
author_role author
author2 Mendes, Bruno
Faverani, Leonardo Perez
Alexandre, Cleber Nunes
Jesus, Giorge Pessoa de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Osborne, Patrick Rocha
Mendes, Bruno
Faverani, Leonardo Perez
Alexandre, Cleber Nunes
Jesus, Giorge Pessoa de
dc.subject.por.fl_str_mv Osteonecrose
Maxila
Osteonecrose associada a bifosfonatos.
Osteonecrosis
Maxilar
Osteonecrosis de los maxilares asociada a bifosfonatos.
Osteonecrose
Maxila
Biphosphonate- associated osteonecrosis of the jaw.
topic Osteonecrose
Maxila
Osteonecrose associada a bifosfonatos.
Osteonecrosis
Maxilar
Osteonecrosis de los maxilares asociada a bifosfonatos.
Osteonecrose
Maxila
Biphosphonate- associated osteonecrosis of the jaw.
description Objective: to describe the clinical case of a patient with multiple myeloma, who developed maxillary osteonecrosis induced by anti-resorptive medication (bisphosphonate) submitted to a conservative and surgical therapeutic approach and subsequent prosthetic rehabilitation. Patients and methods: the case report is presented based on a simple review of the literature and clinical experience for the diagnosis, clinical staging of the lesion, carrying out the excision of the necrotic bone, debridement, lesion control and making a obturator prosthesis. Results: Despite the difficulty offered by the pathological condition and continuous use of medication, the treatment employed was successful, restoring health and providing a better quality of life to the patient, which allowed the obturation prosthesis to be made in the 8-month postoperative period. Conclusion: The result obtained emphasizes the importance of knowledge of the staging of the lesion for the application of the treatment protocol, in addition to recognizing patients at risk for the practice of prevention in dental treatments.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/9415
10.33448/rsd-v9i11.9415
url https://rsdjournal.org/index.php/rsd/article/view/9415
identifier_str_mv 10.33448/rsd-v9i11.9415
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/9415/8592
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 11; e1179119415
Research, Society and Development; Vol. 9 Núm. 11; e1179119415
Research, Society and Development; v. 9 n. 11; e1179119415
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
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instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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