Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019

Detalhes bibliográficos
Autor(a) principal: Soccal, Fernanda de Araujo
Data de Publicação: 2022
Outros Autores: Miguel, Natalia Blanco, Fernandes, Camilo, Silva, Franciele Cascaes da
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33803
Resumo: Objective: To describe the epidemiological profile and evaluate the clinical outcomes of patients with multidrug-resistant tuberculosis in the state of Santa Catarina, notified between 2009 and 2019. Methods: A cross-sectional observational study, using the “Sistema de Informação de Tratamentos Especiais da Tuberculose” (SITETB) database, which included all reported patients with multidrug-resistant tuberculosis in Santa Catarina state between January 2009 and December 2019. Results: Among 265 participants, the most prevalent sociodemographic characteristics were age between 20 and 59 years (90.2%), male (69.8%), white ethnicity (85.2%) and with 7 or fewer years of schooling (65.6%). There was a greater number of notifications in regions outside of Grande Florianópolis (66.4%), unsalaried patients (58.5%), with a predominance of pulmonary (91.6%) and non-bilateral (56.2%) clinical forms, with complete treatment (69.8%). The most prevalent comorbidities were the use of illicit drugs (23.4%), smoking (30.9%), alcoholism (23.8%), AIDS (16.6%) and Diabetes Mellitus (9.5%). Regarding clinical outcomes, there was statistical significance in the association of ethnicity (p=0.020) and education (p=0.009) with the clinical outcome “complete treatment”. Conclusions: The patients’ profile is mostly composed of men, of white ethnicity, between 20 and 59 years old, with 7 or fewer years of schooling, unsalaried, reported in regions outside of Grande Florianópolis, with pulmonary and non-bilateral clinical form, who completed the treatment.
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spelling Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019Evaluación del perfil epidemiológico y evolución clínica de pacientes con tuberculosis multiresistente en el estado de Santa Catarina entre 2009 y 2019Avaliação do perfil epidemiológico e dos desfechos clínicos de pacientes com tuberculose multirresistente no estado de Santa Catarina entre os anos de 2009 e 2019TuberculoseMycobacterium tuberculosisResistência a MedicamentosTuberculose Resistente a Múltiplos Medicamentos.TuberculosisMycobacterium tuberculosisResistencia a MedicamentosTuberculosis Resistente a Múltiples Medicamentos.TuberculosisMycobacterium tuberculosisDrug ResistanceMultidrug-Resistant.Objective: To describe the epidemiological profile and evaluate the clinical outcomes of patients with multidrug-resistant tuberculosis in the state of Santa Catarina, notified between 2009 and 2019. Methods: A cross-sectional observational study, using the “Sistema de Informação de Tratamentos Especiais da Tuberculose” (SITETB) database, which included all reported patients with multidrug-resistant tuberculosis in Santa Catarina state between January 2009 and December 2019. Results: Among 265 participants, the most prevalent sociodemographic characteristics were age between 20 and 59 years (90.2%), male (69.8%), white ethnicity (85.2%) and with 7 or fewer years of schooling (65.6%). There was a greater number of notifications in regions outside of Grande Florianópolis (66.4%), unsalaried patients (58.5%), with a predominance of pulmonary (91.6%) and non-bilateral (56.2%) clinical forms, with complete treatment (69.8%). The most prevalent comorbidities were the use of illicit drugs (23.4%), smoking (30.9%), alcoholism (23.8%), AIDS (16.6%) and Diabetes Mellitus (9.5%). Regarding clinical outcomes, there was statistical significance in the association of ethnicity (p=0.020) and education (p=0.009) with the clinical outcome “complete treatment”. Conclusions: The patients’ profile is mostly composed of men, of white ethnicity, between 20 and 59 years old, with 7 or fewer years of schooling, unsalaried, reported in regions outside of Grande Florianópolis, with pulmonary and non-bilateral clinical form, who completed the treatment.Objetivo: Rastrear el perfil epidemiológico y evaluar los resultados clínicos de pacientes con tuberculosis multidrogorresistente en el estado de Santa Catarina, notificados entre los años de 2009 y 2019. Métodos: Estudio observacional transversal, utilizando la base de datos del “Sistema de Informação de Tratamentos Especiais da Tuberculose”, que se incluyó pacientes notificados con tuberculosis multidrogorresistente en Santa Catarina entre enero de 2009 y diciembre de 2019. Resultados: Entre 265 participantes, las características sociodemográficas más prevalentes fueron edad entre 20 y 59 años (90,2%), sexo masculino (69,8%). ), etnia blanca (85,2%) y con escolaridad menor o igual a 7 años (65,6%). Hubo un número mayor de notificaciones fuera de la Gran Florianópolis (66,4%), pacientes autónomos (58,5%), con forma clínica pulmonar (91,6%), no bilateral (56,2%), con tratamiento completo (69,8%). Las enfermedades más prevalentes fueron el consumo de drogas ilícitas (23,4%), el tabaquismo (30,9%), el consumo de alcohol (23,8%), el sida (16,6%) y la diabetes mellitus (9,5%). En cuanto a los resultados clínicos, hubo significación estadística en la asociación de la etnia (p=0,020) y la escolaridad (p=0,009) con el resultado clínico “tratamiento completo”. Conclusión: El perfil encontrado está compuesto principalmente por hombres, de etnia blanca, entre 20 y 59 años, menos o igual a 7 años de escolaridad, autónomos, reportados fuera de la Gran Florianópolis, con forma clínica pulmonar, no bilateral y que han completado el tratamiento.Objetivo: Traçar o perfil epidemiológico e avaliar os desfechos clínicos de pacientes com tuberculose multirresistente no Estado de Santa Catarina, notificados entre os anos de 2009 e 2019. Métodos: Estudo observacional transversal, utilizando banco de dados do Sistema de Informação de Tratamentos Especiais da Tuberculose, do qual fizeram parte pacientes notificados com tuberculose multirresistente em Santa Catarina entre janeiro de 2009 e dezembro de 2019. Resultados: Dentre 265 participantes, as características sociodemográficas de maior prevalência foram idade entre 20 e 59 anos (90,2%), sexo masculino (69,8%), etnia branca (85,2%) e com escolaridade menor ou igual a 7 anos (65,6%). Houve maior número de notificações fora da Grande Florianópolis (66,4%), pacientes não assalariados (58,5%), com forma clínica pulmonar (91,6%), não bilateral (56,2%), com tratamento completo (69,8%). Os agravos mais prevalentes foram uso de drogas ilícitas (23,4%), tabagismo (30,9%), etilismo (23,8%), AIDS (16,6%) e Diabetes Mellitus (9,5%). Sobre os desfechos clínicos, evidenciou-se significância estatística na associação de etnia (p=0,020) e escolaridade (p=0,009) com desfecho clínico “tratamento completo”. Conclusão: O perfil encontrado é composto, majoritariamente, por homens, etnia branca, entre 20 e 59 anos, escolaridade menor ou igual a 7 anos, não assalariados, notificados fora da Grande Florianópolis, com forma clínica pulmonar, não bilateral e que completaram tratamento.Research, Society and Development2022-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3380310.33448/rsd-v11i11.33803Research, Society and Development; Vol. 11 No. 11; e544111133803Research, Society and Development; Vol. 11 Núm. 11; e544111133803Research, Society and Development; v. 11 n. 11; e5441111338032525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33803/28694Copyright (c) 2022 Fernanda de Araujo Soccal; Natalia Blanco Miguel; Camilo Fernandes; Franciele Cascaes da Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSoccal, Fernanda de AraujoMiguel, Natalia BlancoFernandes, CamiloSilva, Franciele Cascaes da2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33803Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:21.046666Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
Evaluación del perfil epidemiológico y evolución clínica de pacientes con tuberculosis multiresistente en el estado de Santa Catarina entre 2009 y 2019
Avaliação do perfil epidemiológico e dos desfechos clínicos de pacientes com tuberculose multirresistente no estado de Santa Catarina entre os anos de 2009 e 2019
title Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
spellingShingle Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
Soccal, Fernanda de Araujo
Tuberculose
Mycobacterium tuberculosis
Resistência a Medicamentos
Tuberculose Resistente a Múltiplos Medicamentos.
Tuberculosis
Mycobacterium tuberculosis
Resistencia a Medicamentos
Tuberculosis Resistente a Múltiples Medicamentos.
Tuberculosis
Mycobacterium tuberculosis
Drug Resistance
Multidrug-Resistant.
title_short Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
title_full Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
title_fullStr Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
title_full_unstemmed Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
title_sort Evaluation of the epidemiological profile and clinical outcomes of patients with multi-resistant tuberculosis in the state of Santa Catarina between 2009 and 2019
author Soccal, Fernanda de Araujo
author_facet Soccal, Fernanda de Araujo
Miguel, Natalia Blanco
Fernandes, Camilo
Silva, Franciele Cascaes da
author_role author
author2 Miguel, Natalia Blanco
Fernandes, Camilo
Silva, Franciele Cascaes da
author2_role author
author
author
dc.contributor.author.fl_str_mv Soccal, Fernanda de Araujo
Miguel, Natalia Blanco
Fernandes, Camilo
Silva, Franciele Cascaes da
dc.subject.por.fl_str_mv Tuberculose
Mycobacterium tuberculosis
Resistência a Medicamentos
Tuberculose Resistente a Múltiplos Medicamentos.
Tuberculosis
Mycobacterium tuberculosis
Resistencia a Medicamentos
Tuberculosis Resistente a Múltiples Medicamentos.
Tuberculosis
Mycobacterium tuberculosis
Drug Resistance
Multidrug-Resistant.
topic Tuberculose
Mycobacterium tuberculosis
Resistência a Medicamentos
Tuberculose Resistente a Múltiplos Medicamentos.
Tuberculosis
Mycobacterium tuberculosis
Resistencia a Medicamentos
Tuberculosis Resistente a Múltiples Medicamentos.
Tuberculosis
Mycobacterium tuberculosis
Drug Resistance
Multidrug-Resistant.
description Objective: To describe the epidemiological profile and evaluate the clinical outcomes of patients with multidrug-resistant tuberculosis in the state of Santa Catarina, notified between 2009 and 2019. Methods: A cross-sectional observational study, using the “Sistema de Informação de Tratamentos Especiais da Tuberculose” (SITETB) database, which included all reported patients with multidrug-resistant tuberculosis in Santa Catarina state between January 2009 and December 2019. Results: Among 265 participants, the most prevalent sociodemographic characteristics were age between 20 and 59 years (90.2%), male (69.8%), white ethnicity (85.2%) and with 7 or fewer years of schooling (65.6%). There was a greater number of notifications in regions outside of Grande Florianópolis (66.4%), unsalaried patients (58.5%), with a predominance of pulmonary (91.6%) and non-bilateral (56.2%) clinical forms, with complete treatment (69.8%). The most prevalent comorbidities were the use of illicit drugs (23.4%), smoking (30.9%), alcoholism (23.8%), AIDS (16.6%) and Diabetes Mellitus (9.5%). Regarding clinical outcomes, there was statistical significance in the association of ethnicity (p=0.020) and education (p=0.009) with the clinical outcome “complete treatment”. Conclusions: The patients’ profile is mostly composed of men, of white ethnicity, between 20 and 59 years old, with 7 or fewer years of schooling, unsalaried, reported in regions outside of Grande Florianópolis, with pulmonary and non-bilateral clinical form, who completed the treatment.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33803
10.33448/rsd-v11i11.33803
url https://rsdjournal.org/index.php/rsd/article/view/33803
identifier_str_mv 10.33448/rsd-v11i11.33803
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33803/28694
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 11; e544111133803
Research, Society and Development; Vol. 11 Núm. 11; e544111133803
Research, Society and Development; v. 11 n. 11; e544111133803
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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