Drug interactions between herbal medicines and oral contraceptives

Detalhes bibliográficos
Autor(a) principal: Valmiro, Daniella Jordão
Data de Publicação: 2021
Outros Autores: Pinto, Lucas Moyses, Barbosa, Lucas Nascimento, Araújo, Luiza Beatriz Carvalho de, Gonzaga, Rodrigo Vieira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/21331
Resumo: The use of herbal medicines has grown considerably in recent years, due to the erroneous thought that products of plant origin are harmless, and therefore do not cause adverse effects or have drug interactions. The use of these drugs with oral contraceptives can bring risks to patients. The potential negative clinical effects that can be caused by these drug interactions must be emphasized to prevent risks and ensure the effectiveness of this contraceptive method that is one of the most used by women seeking to prevent pregnancy. The users of herbal medicines usually believe that herbal medicine is a therapeutic alternative free of adverse effects and/or incapable of causing drug interactions, but herbal medicines are composed of several chemical compounds, which, in turn, may be responsible for antagonistic and/or synergistic effects with other drugs. The main interactions that can occur with contraceptives are with popularly used herbal medicines such as licorice, alfalfa, cannabis, cimicifuga, St. John's wort, ginseng, kava-kava, saw palmetto, sene, and soy. The herbal medicines have several chemical compounds, among which we highlight the secondary metabolites, responsible for the pharmacological actions and mechanism of action of drug interactions, which are often similar in plants that have in their composition the same metabolites, as in the case of saponins and isoflavones that reduce the speed of biotransformation of oral contraceptives.
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spelling Drug interactions between herbal medicines and oral contraceptivesInteraciones farmacológicas entre medicamentos a base de plantas y anticonceptivos oralesInterações medicamentosas entre fitoterápicos e contraceptivos oraisOral ContraceptivesDrug InteractionsPhytotherapeutic drugs.Anticonceptivos OralesInteracciones con Otros MedicamentosMedicamentos fitoterápicos.Contraceptivos OraisInterações MedicamentosasMedicamentos fitoterápicos.The use of herbal medicines has grown considerably in recent years, due to the erroneous thought that products of plant origin are harmless, and therefore do not cause adverse effects or have drug interactions. The use of these drugs with oral contraceptives can bring risks to patients. The potential negative clinical effects that can be caused by these drug interactions must be emphasized to prevent risks and ensure the effectiveness of this contraceptive method that is one of the most used by women seeking to prevent pregnancy. The users of herbal medicines usually believe that herbal medicine is a therapeutic alternative free of adverse effects and/or incapable of causing drug interactions, but herbal medicines are composed of several chemical compounds, which, in turn, may be responsible for antagonistic and/or synergistic effects with other drugs. The main interactions that can occur with contraceptives are with popularly used herbal medicines such as licorice, alfalfa, cannabis, cimicifuga, St. John's wort, ginseng, kava-kava, saw palmetto, sene, and soy. The herbal medicines have several chemical compounds, among which we highlight the secondary metabolites, responsible for the pharmacological actions and mechanism of action of drug interactions, which are often similar in plants that have in their composition the same metabolites, as in the case of saponins and isoflavones that reduce the speed of biotransformation of oral contraceptives.El uso de los medicamentos a base de plantas ha crecido considerablemente en los últimos años, debido al pensamiento erróneo de que los productos de origen vegetal no traen perjuicios, por lo que no causan efectos adversos y tampoco tienen interacciones farmacológicas. El uso de estos fármacos con los anticonceptivos orales puede traer riesgos a las pacientes, por lo tanto, se debe enfatizar los potenciales efectos clínicos negativos que pueden ser causados por estas interacciones farmacológicas para prevenir riesgos y asegurar la efectividad de este método anticonceptivo que es uno de los más utilizados por las mujeres que buscan prevenir el embarazo. Los usuarios de fitoterápicos suelen creer que la fitoterapia es una alternativa terapéutica libre de efectos adversos y/o incapaz de provocar interacciones farmacológicas, ya que los fitoterápicos están formados por varios compuestos químicos, que a su vez pueden ser responsables de efectos antagónicos y/o sinérgicos con otros fármacos. Las principales interacciones que pueden producirse con los anticonceptivos son con las hierbas medicinales de uso popular, como el regaliz, la alfalfa, el cannabis, la cimífuga, la hierba de San Juan, el ginseng, el kavakava, la palma enana americana, el sene y la soja. Los medicamentos a base de plantas tienen varios compuestos químicos, entre los que destacan los metabolitos secundarios, responsables de las acciones farmacológicas y del mecanismo de acción de las interacciones de los medicamentos, que suelen ser similares en las plantas que tienen en su composición los mismos metabolitos, como es el caso de las saponinas y las isoflavonas que reducen la velocidad de biotransformación de los anticonceptivos orales.O uso de fitoterápicos cresceu consideravelmente nos últimos anos, devido ao pensamento errôneo de que os produtos de origens vegetais não trazem danos, portanto não causam efeitos adversos e nem possuem interações medicamentosas. O uso desses medicamentos com os contraceptivos orais pode trazer riscos às pacientes, portanto, os potenciais efeitos clínicos negativos que podem ser causados por essas interações medicamentosas devem ser enfatizados para prevenir riscos e garantir a eficácia desse método contraceptivo que é um dos mais utilizados por mulheres que buscam prevenir a gravidez. As usuárias de fitoterápicos costumam acreditar que a fitoterapia é uma alternativa terapêutica isenta de efeitos adversos e/ou incapazes de causar interações medicamentosas, sendo os fitoterápicos constituídos de vários compostos químicos, que por sua vez podem ser responsáveis por efeitos antagônicos e/ou sinérgicos com outros medicamentos. As principais interações que podem ocorrer com os contraceptivos são com os fitoterápicos popularmente utilizados como o alcaçuz, alfafa, cannabis, cimicífuga, erva de São João, ginseng, kava-kava, saw palmetto, sene e soja. Os fitoterápicos apresentam diversos compostos químicos, dentre eles destacam-se os metabólitos secundários, responsáveis pelas ações farmacológicas e mecanismo de ação das interações medicamentosas, que muitas vezes são similares em plantas que possuem em sua composição os mesmos metabólitos, como no caso das saponinas e isoflavonas que reduzem a velocidade de biotransformação dos anticoncepcionais orais.Research, Society and Development2021-10-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2133110.33448/rsd-v10i13.21331Research, Society and Development; Vol. 10 No. 13; e372101321331Research, Society and Development; Vol. 10 Núm. 13; e372101321331Research, Society and Development; v. 10 n. 13; e3721013213312525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/21331/19012Copyright (c) 2021 Daniella Jordão Valmiro; Lucas Moyses Pinto; Lucas Nascimento Barbosa; Luiza Beatriz Carvalho de Araújo; Rodrigo Vieira Gonzagahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessValmiro, Daniella JordãoPinto, Lucas MoysesBarbosa, Lucas NascimentoAraújo, Luiza Beatriz Carvalho de Gonzaga, Rodrigo Vieira 2021-11-21T18:26:28Zoai:ojs.pkp.sfu.ca:article/21331Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:46.177650Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Drug interactions between herbal medicines and oral contraceptives
Interaciones farmacológicas entre medicamentos a base de plantas y anticonceptivos orales
Interações medicamentosas entre fitoterápicos e contraceptivos orais
title Drug interactions between herbal medicines and oral contraceptives
spellingShingle Drug interactions between herbal medicines and oral contraceptives
Valmiro, Daniella Jordão
Oral Contraceptives
Drug Interactions
Phytotherapeutic drugs.
Anticonceptivos Orales
Interacciones con Otros Medicamentos
Medicamentos fitoterápicos.
Contraceptivos Orais
Interações Medicamentosas
Medicamentos fitoterápicos.
title_short Drug interactions between herbal medicines and oral contraceptives
title_full Drug interactions between herbal medicines and oral contraceptives
title_fullStr Drug interactions between herbal medicines and oral contraceptives
title_full_unstemmed Drug interactions between herbal medicines and oral contraceptives
title_sort Drug interactions between herbal medicines and oral contraceptives
author Valmiro, Daniella Jordão
author_facet Valmiro, Daniella Jordão
Pinto, Lucas Moyses
Barbosa, Lucas Nascimento
Araújo, Luiza Beatriz Carvalho de
Gonzaga, Rodrigo Vieira
author_role author
author2 Pinto, Lucas Moyses
Barbosa, Lucas Nascimento
Araújo, Luiza Beatriz Carvalho de
Gonzaga, Rodrigo Vieira
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Valmiro, Daniella Jordão
Pinto, Lucas Moyses
Barbosa, Lucas Nascimento
Araújo, Luiza Beatriz Carvalho de
Gonzaga, Rodrigo Vieira
dc.subject.por.fl_str_mv Oral Contraceptives
Drug Interactions
Phytotherapeutic drugs.
Anticonceptivos Orales
Interacciones con Otros Medicamentos
Medicamentos fitoterápicos.
Contraceptivos Orais
Interações Medicamentosas
Medicamentos fitoterápicos.
topic Oral Contraceptives
Drug Interactions
Phytotherapeutic drugs.
Anticonceptivos Orales
Interacciones con Otros Medicamentos
Medicamentos fitoterápicos.
Contraceptivos Orais
Interações Medicamentosas
Medicamentos fitoterápicos.
description The use of herbal medicines has grown considerably in recent years, due to the erroneous thought that products of plant origin are harmless, and therefore do not cause adverse effects or have drug interactions. The use of these drugs with oral contraceptives can bring risks to patients. The potential negative clinical effects that can be caused by these drug interactions must be emphasized to prevent risks and ensure the effectiveness of this contraceptive method that is one of the most used by women seeking to prevent pregnancy. The users of herbal medicines usually believe that herbal medicine is a therapeutic alternative free of adverse effects and/or incapable of causing drug interactions, but herbal medicines are composed of several chemical compounds, which, in turn, may be responsible for antagonistic and/or synergistic effects with other drugs. The main interactions that can occur with contraceptives are with popularly used herbal medicines such as licorice, alfalfa, cannabis, cimicifuga, St. John's wort, ginseng, kava-kava, saw palmetto, sene, and soy. The herbal medicines have several chemical compounds, among which we highlight the secondary metabolites, responsible for the pharmacological actions and mechanism of action of drug interactions, which are often similar in plants that have in their composition the same metabolites, as in the case of saponins and isoflavones that reduce the speed of biotransformation of oral contraceptives.
publishDate 2021
dc.date.none.fl_str_mv 2021-10-16
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21331
10.33448/rsd-v10i13.21331
url https://rsdjournal.org/index.php/rsd/article/view/21331
identifier_str_mv 10.33448/rsd-v10i13.21331
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21331/19012
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 13; e372101321331
Research, Society and Development; Vol. 10 Núm. 13; e372101321331
Research, Society and Development; v. 10 n. 13; e372101321331
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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