Antimicrobial analysis of Mikania glomerata extract

Detalhes bibliográficos
Autor(a) principal: Silva, Vanessa Cristina de Melo
Data de Publicação: 2021
Outros Autores: Vilar, Daniela de Araújo, Vilar, Marina Suênia de Araújo, Mélo , Mayanny Celly de Sales, Rodrigues, Patricia de Luna
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/16551
Resumo: The treatment and cure of various infections suffered great advances after the discovery of antimicrobials, however the indiscriminate use of these drugs caused bacterial resistance, triggering public health problems such as increased treatment costs. Among the search for new effective and safe therapeutic alternatives is the use of herbal medicines. The work aimed to evaluate in vitro the antimicrobial potential of the extract of Mikania glomerata (guaco) through the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration. The microdilution technique was performed in order to determine the efficacy of the hydroalcoholic extract of Mikania glomerata against the standard strains of Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC25923). Thus, it was found that the extract showed antimicrobial activity for the gram-positive bacteria Staphylococcus aureus (ATCC 25923) and for the gram-negative bacteria Escherichia coli (ATCC 25922). The hydroalcoholic extract of Mikania glomerata was shown to be active with inhibition of microbial growth in varying concentrations in relation to all the microorganisms used in the study, with the antimicrobial activity of the extract possibly attributed to the existence of active compounds such as kaurenic acid and cinamolgrandifloric acid.
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spelling Antimicrobial analysis of Mikania glomerata extractAnálisis antimicrobiano del extracto de Mikania glomerataAnálise antimicrobiana do extrato de Mikania glomerataResistência bacterianaFitoterápicosMikania glomerataAtividade antimicrobiana.Resistência bacterianaFitoterápicosMikania glomerataAtividade antimicrobiana.Bacteria lresistanceHerbal medicinesMikania glomerataAntimicrobial activity.The treatment and cure of various infections suffered great advances after the discovery of antimicrobials, however the indiscriminate use of these drugs caused bacterial resistance, triggering public health problems such as increased treatment costs. Among the search for new effective and safe therapeutic alternatives is the use of herbal medicines. The work aimed to evaluate in vitro the antimicrobial potential of the extract of Mikania glomerata (guaco) through the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration. The microdilution technique was performed in order to determine the efficacy of the hydroalcoholic extract of Mikania glomerata against the standard strains of Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC25923). Thus, it was found that the extract showed antimicrobial activity for the gram-positive bacteria Staphylococcus aureus (ATCC 25923) and for the gram-negative bacteria Escherichia coli (ATCC 25922). The hydroalcoholic extract of Mikania glomerata was shown to be active with inhibition of microbial growth in varying concentrations in relation to all the microorganisms used in the study, with the antimicrobial activity of the extract possibly attributed to the existence of active compounds such as kaurenic acid and cinamolgrandifloric acid.El tratamiento y curación de varias infecciones sufrió grandes avances tras el descubrimiento de los antimicrobianos, sin embargo, el uso indiscriminado de estos fármacos provocó resistencias bacterianas, desencadenando problemas de salud pública como el aumento de los costos del tratamiento. Entre la búsqueda de nuevas alternativas terapéuticas eficaces y seguras se encuentra el uso de medicamentos a base de hierbas. El trabajo tuvo como objetivo evaluar in vitro el potencial antimicrobiano del extracto de Mikania glomerata (guaco) a través de la Concentración Mínima Inhibitoria y la Concentración Mínima Bactericida. Se realizó la técnica de microdilución para determinar la eficacia del extracto hidroalcohólico de Mikania glomerata frente a las cepas estándar de Escherichia coli (ATCC 25922) y Staphylococcus aureus (ATCC25923). Así, se encontró que el extracto mostró actividad antimicrobiana para la bacteria grampositiva Staphylococcus aureus (ATCC 25923) y para la bacteria gramnegativa Escherichia coli (ATCC 25922). El extracto hidroalcohólico de Mikania glomerata demostró ser activo con inhibición del crecimiento microbiano en concentraciones variables en relación con todos los microorganismos utilizados en el estudio, con la actividad antimicrobiana del extracto posiblemente atribuida a la existencia de compuestos activos como el ácido kaurénico y ácido cinamolgrandiflorico.O tratamento e a cura de diversas infecções sofreram grande avanço após a descoberta dos antimicrobianos, no entanto o uso indiscriminado desses medicamentos ocasionou a resistência bacteriana, desencadeando problemas de saúde pública como elevação de custos nos tratamentos. Entre a procura por novas alternativas terapêuticas eficazes e seguras encontra-se o uso de fitoterápicos. O trabalho objetivou avaliar in vitro o potencial antimicrobiano do extrato de Mikania glomerata (guaco) através da Concentração Inibitória Mínima e Concentração Bactericida Mínima. Realizou-se a técnica de microdiluição a fim de determinar a eficácia do extrato hidroalcóolico de Mikania glomerata frente a cepas padrão de Escherichia coli (ATCC 25922) e Staphylococcus aureus (ATCC25923). Dessa forma, verificou-se que o extrato apresentou atividade antimicrobiana para a bactéria gram-positiva Staphylococcus aureus (ATCC 25923) e para a bactéria gram-negativa Escherichia coli (ATCC 25922). O extrato hidroalcoólico de Mikania glomerata mostrou-se ativo apresentando inibição do crescimento microbiano em concentrações variadas frente a todos os microrganismos utilizados no estudo, sendo a atividade antimicrobiana do extrato possivelmente atribuída a existência de compostos ativos como ácido caurenoico e o ácido cinamolgrandiflórico.Research, Society and Development2021-06-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/16551Research, Society and Development; Vol. 10 No. 7; e22610716551Research, Society and Development; Vol. 10 Núm. 7; e22610716551Research, Society and Development; v. 10 n. 7; e226107165512525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/16551/14726Copyright (c) 2021 Vanessa Cristina de Melo Silva; Daniela de Araújo Vilar; Marina Suênia de Araújo Vilar; Mayanny Celly de Sales Mélo ; Patricia de Luna Rodrigueshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Vanessa Cristina de Melo Vilar, Daniela de Araújo Vilar, Marina Suênia de Araújo Mélo , Mayanny Celly de Sales Rodrigues, Patricia de Luna 2021-07-18T21:07:03Zoai:ojs.pkp.sfu.ca:article/16551Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:37:04.291719Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Antimicrobial analysis of Mikania glomerata extract
Análisis antimicrobiano del extracto de Mikania glomerata
Análise antimicrobiana do extrato de Mikania glomerata
title Antimicrobial analysis of Mikania glomerata extract
spellingShingle Antimicrobial analysis of Mikania glomerata extract
Silva, Vanessa Cristina de Melo
Resistência bacteriana
Fitoterápicos
Mikania glomerata
Atividade antimicrobiana.
Resistência bacteriana
Fitoterápicos
Mikania glomerata
Atividade antimicrobiana.
Bacteria lresistance
Herbal medicines
Mikania glomerata
Antimicrobial activity.
title_short Antimicrobial analysis of Mikania glomerata extract
title_full Antimicrobial analysis of Mikania glomerata extract
title_fullStr Antimicrobial analysis of Mikania glomerata extract
title_full_unstemmed Antimicrobial analysis of Mikania glomerata extract
title_sort Antimicrobial analysis of Mikania glomerata extract
author Silva, Vanessa Cristina de Melo
author_facet Silva, Vanessa Cristina de Melo
Vilar, Daniela de Araújo
Vilar, Marina Suênia de Araújo
Mélo , Mayanny Celly de Sales
Rodrigues, Patricia de Luna
author_role author
author2 Vilar, Daniela de Araújo
Vilar, Marina Suênia de Araújo
Mélo , Mayanny Celly de Sales
Rodrigues, Patricia de Luna
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Vanessa Cristina de Melo
Vilar, Daniela de Araújo
Vilar, Marina Suênia de Araújo
Mélo , Mayanny Celly de Sales
Rodrigues, Patricia de Luna
dc.subject.por.fl_str_mv Resistência bacteriana
Fitoterápicos
Mikania glomerata
Atividade antimicrobiana.
Resistência bacteriana
Fitoterápicos
Mikania glomerata
Atividade antimicrobiana.
Bacteria lresistance
Herbal medicines
Mikania glomerata
Antimicrobial activity.
topic Resistência bacteriana
Fitoterápicos
Mikania glomerata
Atividade antimicrobiana.
Resistência bacteriana
Fitoterápicos
Mikania glomerata
Atividade antimicrobiana.
Bacteria lresistance
Herbal medicines
Mikania glomerata
Antimicrobial activity.
description The treatment and cure of various infections suffered great advances after the discovery of antimicrobials, however the indiscriminate use of these drugs caused bacterial resistance, triggering public health problems such as increased treatment costs. Among the search for new effective and safe therapeutic alternatives is the use of herbal medicines. The work aimed to evaluate in vitro the antimicrobial potential of the extract of Mikania glomerata (guaco) through the Minimum Inhibitory Concentration and Minimum Bactericidal Concentration. The microdilution technique was performed in order to determine the efficacy of the hydroalcoholic extract of Mikania glomerata against the standard strains of Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC25923). Thus, it was found that the extract showed antimicrobial activity for the gram-positive bacteria Staphylococcus aureus (ATCC 25923) and for the gram-negative bacteria Escherichia coli (ATCC 25922). The hydroalcoholic extract of Mikania glomerata was shown to be active with inhibition of microbial growth in varying concentrations in relation to all the microorganisms used in the study, with the antimicrobial activity of the extract possibly attributed to the existence of active compounds such as kaurenic acid and cinamolgrandifloric acid.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-19
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/16551
url https://rsdjournal.org/index.php/rsd/article/view/16551
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/16551/14726
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 7; e22610716551
Research, Society and Development; Vol. 10 Núm. 7; e22610716551
Research, Society and Development; v. 10 n. 7; e22610716551
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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