Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study

Detalhes bibliográficos
Autor(a) principal: Gusmão, Isabel Celeste Caires Pereira
Data de Publicação: 2022
Outros Autores: Pithon, Matheus Melo, Santos , Alessandra Estevam dos, Silva , Tainá Souza, Sampaio, Fabio Correia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/27141
Resumo: The aim of this study was to evaluate the antimicrobial susceptibility of essential oil from Lippia sidoides Cham, against Aggregatibacter actinomycetecomitans ATCC 29522 and Porphyromonas gingivalis ATCC 0644. The antimicrobial activity of L.sidoides Cham oil extracted from leaves and flowers and the constituents thymol and carvacrol through Minimum Inhibitory Concentration (MIC) and minimal bactericidal determination (CBM) against periodontopathogens Aggregatibacter actinomycetemcomitans (ATCC), Porphyromonas gingivalis (ATCC ). Te results revealed that the MIC recorded was 44.23 to 39.3 mg/mL for thymol and 28.45 to 28.15 mg/mL for carvacrol. These concentrations were considered bactericidal when CBM was evaluated. All analyzed substances showed a synergistic effect in association with chlorhexidine. Thus, it can be concluded that Lippia sidoides Cham was effective in inhibiting the in vitro growth of periodontopathogenic bacteria, presenting, therefore, biotechnological potential for use in the field of dentistry.
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spelling Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro studyActividad antibacteriana de Lippia sidoides Cham frente a periodontopatógenos: estudio in vitroAtividade antibacteriana da Lippia sidoides Cham contra periodontopatógenos: estudo In vitroChlorhexidinePeriodonticsPeriodontal diseases.ClorhexidinaPeriodonciaEnfermedades periodontales.ClorexidinaPeriodontiaDoenças periodontais.The aim of this study was to evaluate the antimicrobial susceptibility of essential oil from Lippia sidoides Cham, against Aggregatibacter actinomycetecomitans ATCC 29522 and Porphyromonas gingivalis ATCC 0644. The antimicrobial activity of L.sidoides Cham oil extracted from leaves and flowers and the constituents thymol and carvacrol through Minimum Inhibitory Concentration (MIC) and minimal bactericidal determination (CBM) against periodontopathogens Aggregatibacter actinomycetemcomitans (ATCC), Porphyromonas gingivalis (ATCC ). Te results revealed that the MIC recorded was 44.23 to 39.3 mg/mL for thymol and 28.45 to 28.15 mg/mL for carvacrol. These concentrations were considered bactericidal when CBM was evaluated. All analyzed substances showed a synergistic effect in association with chlorhexidine. Thus, it can be concluded that Lippia sidoides Cham was effective in inhibiting the in vitro growth of periodontopathogenic bacteria, presenting, therefore, biotechnological potential for use in the field of dentistry.El objetivo de este estudio fue evaluar la susceptibilidad antimicrobiana del aceite esencial de Lippia sidoides Cham frente a Aggregatibacter actinomycetecomitans ATCC 29522 y Porphyromonas gingivalis ATCC 0644. La actividad antimicrobiana del aceite de L.sidoides Cham extraído de hojas y flores y los constituyentes timol y carvacrol a través de la Concentración mínima inhibitoria (MIC) y determinación bactericida mínima (MBC) frente a los periodontopatógenos Aggregatibacter actinomycetemcomitans (ATCC), Porphyromonas gingivalis (ATCC). Resultados: revelaron que la CIM registrada fue de 44,23 a 39,3 mg/mL para timol y de 28,45 a 28,15 mg/mL para carvacrol. Estas concentraciones se consideraron bactericidas cuando se evaluó el CBM. Todas las sustancias analizadas mostraron un efecto sinérgico en asociación con la clorhexidina. Por lo tanto, se puede concluir que Lippia sidoides Cham fue eficaz para inhibir el crecimiento in vitro de bacterias periodontopatógenas, presentando, por tanto, potencial biotecnológico para su uso en odontología.O objetivo dessse estudo foi avaliar a susceptibilidade antimicrobiana do óleo essencial da Lippia sidoides Cham, frente a Aggregatibacter actinomycetecomitans ATCC 29522 e Porphyromonas gingivalis ATCC 0644. A atividade antimicrobiana do óleo da L.sidoides Cham extraídos de folhas e flores e dos constituintes timol e carvacrol através da Concentração Inibitória Mínima (CIM) e determinação bactericida mínima (CBM) frente aos periodontopatógenos Aggregatibacter actinomycetemcomitans (ATCC), Porphyromonas gingivalis (ATCC). Resultados: revelaram que a CIM registrado foi de 44,23 a 39,3 mg/mL para o timol e 28,45 a 28,15 mg/mL para carvacrol. Estas concentrações foram consideradas bactericidas quando a CBM foi avaliada. Todas as substâncias analisadas apresentaram efeito sinérgico em associação com a clorexidina. Dessa forma pode-se concluir que a Lippia sidoides Cham foi eficaz para inibir o crescimento in vitro das bactérias periodontopatogênicas apresentando, portanto, potencial biotecnológico para uso na área de odontologia.Research, Society and Development2022-05-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2714110.33448/rsd-v11i7.27141Research, Society and Development; Vol. 11 No. 7; e3311727141Research, Society and Development; Vol. 11 Núm. 7; e3311727141Research, Society and Development; v. 11 n. 7; e33117271412525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/27141/25596Copyright (c) 2022 Isabel Celeste Caires Pereira Gusmão; Matheus Melo Pithon; Alessandra Estevam dos Santos ; Tainá Souza Silva ; Fabio Correia Sampaiohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGusmão, Isabel Celeste Caires Pereira Pithon, Matheus Melo Santos , Alessandra Estevam dos Silva , Tainá Souza Sampaio, Fabio Correia 2022-06-06T15:12:05Zoai:ojs.pkp.sfu.ca:article/27141Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:57.708716Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
Actividad antibacteriana de Lippia sidoides Cham frente a periodontopatógenos: estudio in vitro
Atividade antibacteriana da Lippia sidoides Cham contra periodontopatógenos: estudo In vitro
title Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
spellingShingle Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
Gusmão, Isabel Celeste Caires Pereira
Chlorhexidine
Periodontics
Periodontal diseases.
Clorhexidina
Periodoncia
Enfermedades periodontales.
Clorexidina
Periodontia
Doenças periodontais.
title_short Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
title_full Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
title_fullStr Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
title_full_unstemmed Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
title_sort Antibacterial activity of Lippia sidoides Cham against periodontopathogens: an in vitro study
author Gusmão, Isabel Celeste Caires Pereira
author_facet Gusmão, Isabel Celeste Caires Pereira
Pithon, Matheus Melo
Santos , Alessandra Estevam dos
Silva , Tainá Souza
Sampaio, Fabio Correia
author_role author
author2 Pithon, Matheus Melo
Santos , Alessandra Estevam dos
Silva , Tainá Souza
Sampaio, Fabio Correia
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Gusmão, Isabel Celeste Caires Pereira
Pithon, Matheus Melo
Santos , Alessandra Estevam dos
Silva , Tainá Souza
Sampaio, Fabio Correia
dc.subject.por.fl_str_mv Chlorhexidine
Periodontics
Periodontal diseases.
Clorhexidina
Periodoncia
Enfermedades periodontales.
Clorexidina
Periodontia
Doenças periodontais.
topic Chlorhexidine
Periodontics
Periodontal diseases.
Clorhexidina
Periodoncia
Enfermedades periodontales.
Clorexidina
Periodontia
Doenças periodontais.
description The aim of this study was to evaluate the antimicrobial susceptibility of essential oil from Lippia sidoides Cham, against Aggregatibacter actinomycetecomitans ATCC 29522 and Porphyromonas gingivalis ATCC 0644. The antimicrobial activity of L.sidoides Cham oil extracted from leaves and flowers and the constituents thymol and carvacrol through Minimum Inhibitory Concentration (MIC) and minimal bactericidal determination (CBM) against periodontopathogens Aggregatibacter actinomycetemcomitans (ATCC), Porphyromonas gingivalis (ATCC ). Te results revealed that the MIC recorded was 44.23 to 39.3 mg/mL for thymol and 28.45 to 28.15 mg/mL for carvacrol. These concentrations were considered bactericidal when CBM was evaluated. All analyzed substances showed a synergistic effect in association with chlorhexidine. Thus, it can be concluded that Lippia sidoides Cham was effective in inhibiting the in vitro growth of periodontopathogenic bacteria, presenting, therefore, biotechnological potential for use in the field of dentistry.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-14
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27141
10.33448/rsd-v11i7.27141
url https://rsdjournal.org/index.php/rsd/article/view/27141
identifier_str_mv 10.33448/rsd-v11i7.27141
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27141/25596
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 7; e3311727141
Research, Society and Development; Vol. 11 Núm. 7; e3311727141
Research, Society and Development; v. 11 n. 7; e3311727141
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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