Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection

Detalhes bibliográficos
Autor(a) principal: Santos, Letícia Paiva de Carvalho
Data de Publicação: 2022
Outros Autores: Freitas, Moisés Thiago de Souza
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/30541
Resumo: Kidney injury is a syndrome characterized by reduced kidney function and is an important finding in hospitalized patients. Studies have shown significantly elevated levels of renal biomarkers in patients infected with COVID-19. Therefore, the objective of this literature review was to describe changes in renal markers in laboratory tests of hospitalized patients with COVID-19, reporting on the problems caused to the human organism related to infection, the effects of infection on the renal system of hospitalized patients and changes in renal markers in infected patients. It is a theoretical framework developed through the search of publications obtained in the databases: PubMed and SciELO, published in the last 3 years. The descriptors SARS-CoV-2, Renal Failure and Renal Markers were used. Through the analysis of the survey of all the material, it was possible to demonstrate that 25% of hospitalized patients with COVID-19 develop renal failure, presenting an increase in urea and creatine levels, a decrease in the rate of GFR, and the presence of proteinuria and hematuria in the exams. of urine. Regarding complications resulting from SARS-CoV-2 infection, the respiratory, cardiovascular, renal, hepatic, gastrointestinal and neurological systems were the most reported. Given the importance of maintaining kidney integrity and screening through biochemical markers, more research on this topic is needed to improve understanding of kidney damage in COVID-19 cases and its health impact.
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spelling Identification of the change in the profile of renal markers associated with SARS-CoV-2 infectionIdentificación del cambio en el perfil de marcadores renales asociados a la infección por SARS-CoV-2Identificação da mudança do perfil dos marcadores renais associados á infecção por SARS-CoV-2SARS-CoV-2 virusRim InsufficiencyBiochemical markersHealth teaching.Vírus SARS-CoV-2Insuficiência do RimMarcadores BioquímicosEnsino em saúde.Virus SARS-CoV-2Insuficiencia renalMarcadores bioquímicosEnseñanza en salud.Kidney injury is a syndrome characterized by reduced kidney function and is an important finding in hospitalized patients. Studies have shown significantly elevated levels of renal biomarkers in patients infected with COVID-19. Therefore, the objective of this literature review was to describe changes in renal markers in laboratory tests of hospitalized patients with COVID-19, reporting on the problems caused to the human organism related to infection, the effects of infection on the renal system of hospitalized patients and changes in renal markers in infected patients. It is a theoretical framework developed through the search of publications obtained in the databases: PubMed and SciELO, published in the last 3 years. The descriptors SARS-CoV-2, Renal Failure and Renal Markers were used. Through the analysis of the survey of all the material, it was possible to demonstrate that 25% of hospitalized patients with COVID-19 develop renal failure, presenting an increase in urea and creatine levels, a decrease in the rate of GFR, and the presence of proteinuria and hematuria in the exams. of urine. Regarding complications resulting from SARS-CoV-2 infection, the respiratory, cardiovascular, renal, hepatic, gastrointestinal and neurological systems were the most reported. Given the importance of maintaining kidney integrity and screening through biochemical markers, more research on this topic is needed to improve understanding of kidney damage in COVID-19 cases and its health impact.La lesión renal es un síndrome caracterizado por una función renal reducida y es un hallazgo importante en pacientes hospitalizados. Los estudios han mostrado niveles significativamente elevados de biomarcadores renales en pacientes infectados con COVID-19. Por lo tanto, el objetivo de esta revisión bibliográfica fue describir los cambios en los marcadores renales en pruebas de laboratorio de pacientes hospitalizados con COVID-19, informando sobre los problemas que ocasiona al organismo humano relacionados con la infección, los efectos de la infección en el sistema renal de los pacientes hospitalizados y cambios en los marcadores renales en pacientes infectados. Es un marco teórico desarrollado a través de la búsqueda de publicaciones obtenidas en las bases de datos: PubMed y SciELO, publicadas en los últimos 3 años. Se utilizaron los descriptores SARS-CoV-2, Insuficiencia Renal y Marcadores Renales. A través del análisis de la encuesta de todo el material, se pudo evidenciar que el 25% de los pacientes hospitalizados con COVID-19 desarrollan insuficiencia renal, presentando aumento de los niveles de urea y creatina, disminución de la tasa de FG y presencia de de proteinuria y hematuria en los exámenes de orina. En cuanto a las complicaciones derivadas de la infección por SARS-CoV-2, las más reportadas fueron las del sistema respiratorio, cardiovascular, renal, hepático, gastrointestinal y neurológico. Dada la importancia de mantener la integridad renal y la detección a través de marcadores bioquímicos, se necesita más investigación sobre este tema para mejorar la comprensión del daño renal en los casos de COVID-19 y su impacto en la salud.A lesão renal é uma síndrome caracterizada por uma redução da função renal, sendo um achado importante em pacientes hospitalizados. Estudos mostraram níveis significativamente elevados de biomarcadores renais em pacientes infectados com COVID-19. Diante disso, o objetivo dessa revisão de literatura foi descrever as alterações de marcadores renais nos exames laboratoriais de pacientes hospitalizados com COVID-19, relatando sobre os problemas ocasionados ao organismo humano relacionado à infecção, os efeitos da infecção sob sistema renal de pacientes hospitalizados e as alterações de marcadores renais nos pacientes infectados. Trata-se de um referencial teórico desenvolvido através da pesquisa de publicações obtidas nas bases de dados: PubMed e SciELO, publicadas nos últimos 3 anos. Foram utilizados os descritores SARS-CoV-2, Insuficiência Renal e Marcadores Renais. Através da análise do levantamento de todo o material, foi possível demonstrar que 25% dos pacientes internados com COVID-19 desenvolvem Insuficiência Renal, apresentando aumento nos níveis de uréia e creatina, diminuição da taxa de TFG, e presença de proteinúria e hematúria nos exames de urina. Em relação ás complicações decorrentes da infecção pelo SARS-CoV-2 os sistemas respiratório, cardiovascular, renal, hepático, gastrointestinal e neurológico foram os mais relatados. Dada a importância de manter a integridade renal e o rastreio através dos marcadores bioquímicos, são necessárias mais pesquisas sobre esse tópico para melhorar a compreensão dos danos renais nos casos de COVID-19 e seu impacto na saúde.Research, Society and Development2022-06-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3054110.33448/rsd-v11i7.30541Research, Society and Development; Vol. 11 No. 7; e58111730541Research, Society and Development; Vol. 11 Núm. 7; e58111730541Research, Society and Development; v. 11 n. 7; e581117305412525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/30541/26185Copyright (c) 2022 Letícia Paiva de Carvalho Santos; Moisés Thiago de Souza Freitashttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Letícia Paiva de CarvalhoFreitas, Moisés Thiago de Souza2022-06-06T15:12:05Zoai:ojs.pkp.sfu.ca:article/30541Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:47:15.560067Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
Identificación del cambio en el perfil de marcadores renales asociados a la infección por SARS-CoV-2
Identificação da mudança do perfil dos marcadores renais associados á infecção por SARS-CoV-2
title Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
spellingShingle Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
Santos, Letícia Paiva de Carvalho
SARS-CoV-2 virus
Rim Insufficiency
Biochemical markers
Health teaching.
Vírus SARS-CoV-2
Insuficiência do Rim
Marcadores Bioquímicos
Ensino em saúde.
Virus SARS-CoV-2
Insuficiencia renal
Marcadores bioquímicos
Enseñanza en salud.
title_short Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
title_full Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
title_fullStr Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
title_full_unstemmed Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
title_sort Identification of the change in the profile of renal markers associated with SARS-CoV-2 infection
author Santos, Letícia Paiva de Carvalho
author_facet Santos, Letícia Paiva de Carvalho
Freitas, Moisés Thiago de Souza
author_role author
author2 Freitas, Moisés Thiago de Souza
author2_role author
dc.contributor.author.fl_str_mv Santos, Letícia Paiva de Carvalho
Freitas, Moisés Thiago de Souza
dc.subject.por.fl_str_mv SARS-CoV-2 virus
Rim Insufficiency
Biochemical markers
Health teaching.
Vírus SARS-CoV-2
Insuficiência do Rim
Marcadores Bioquímicos
Ensino em saúde.
Virus SARS-CoV-2
Insuficiencia renal
Marcadores bioquímicos
Enseñanza en salud.
topic SARS-CoV-2 virus
Rim Insufficiency
Biochemical markers
Health teaching.
Vírus SARS-CoV-2
Insuficiência do Rim
Marcadores Bioquímicos
Ensino em saúde.
Virus SARS-CoV-2
Insuficiencia renal
Marcadores bioquímicos
Enseñanza en salud.
description Kidney injury is a syndrome characterized by reduced kidney function and is an important finding in hospitalized patients. Studies have shown significantly elevated levels of renal biomarkers in patients infected with COVID-19. Therefore, the objective of this literature review was to describe changes in renal markers in laboratory tests of hospitalized patients with COVID-19, reporting on the problems caused to the human organism related to infection, the effects of infection on the renal system of hospitalized patients and changes in renal markers in infected patients. It is a theoretical framework developed through the search of publications obtained in the databases: PubMed and SciELO, published in the last 3 years. The descriptors SARS-CoV-2, Renal Failure and Renal Markers were used. Through the analysis of the survey of all the material, it was possible to demonstrate that 25% of hospitalized patients with COVID-19 develop renal failure, presenting an increase in urea and creatine levels, a decrease in the rate of GFR, and the presence of proteinuria and hematuria in the exams. of urine. Regarding complications resulting from SARS-CoV-2 infection, the respiratory, cardiovascular, renal, hepatic, gastrointestinal and neurological systems were the most reported. Given the importance of maintaining kidney integrity and screening through biochemical markers, more research on this topic is needed to improve understanding of kidney damage in COVID-19 cases and its health impact.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-05
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/30541
10.33448/rsd-v11i7.30541
url https://rsdjournal.org/index.php/rsd/article/view/30541
identifier_str_mv 10.33448/rsd-v11i7.30541
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/30541/26185
dc.rights.driver.fl_str_mv Copyright (c) 2022 Letícia Paiva de Carvalho Santos; Moisés Thiago de Souza Freitas
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Letícia Paiva de Carvalho Santos; Moisés Thiago de Souza Freitas
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 7; e58111730541
Research, Society and Development; Vol. 11 Núm. 7; e58111730541
Research, Society and Development; v. 11 n. 7; e58111730541
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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