The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/17539 |
Resumo: | Sickle cell anemia is a genetic disease, transmitted by an autosomal recessive inheritance, represented by the existence of sickle-shaped erythrocytes, and highly prevalent in Brazil. Carriers of this pathology are asymptomatic in the first six months of life. Early diagnosis is achieved through neonatal screening, allowing the monitoring of patients before the manifestations and symptoms and, with this, the prevention of possible sequelae and complications. This study was carried out through a qualitative and quantitative bibliographic research, aiming to demonstrate, point out and correlate the main characteristics of this pathology with early diagnosis. Highlighting the main points of articles related to sickle cell anemia and its complications, using national and international publications, from the databases: SCIELO (Scientific Electronic Library Online), PubMed, Academic Google and VHL, in which 21 works were part of the construction of the results. Among these, 4 were found on PubMed, 9 on Sciello,7 on Google Scholar and 1 on the BVS platform. Responding to the objectives described, we can conclude that early diagnosis is essential, as the sooner sickle cell anemia is detected, there is more chance that the patient's quality and life expectancy will increase, with that the neonatal screening plays a fundamental role in this detection. |
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The Importance of Neonatal Screening for the Early Detection of Sickle Cell AnemiaLa Importancia del Cribado Neonatal para la Detección Precoz de la Anemia FalciformeA Importância da Triagem Neonatal para a Detecção Precoce da Anemia FalciformeHemoglobin SSickle Cell AnemiaNeonatal screening.Hemoglobina SAnemia de células falciformesCribado neonatal.Hemoglobina SAnemia FalciformeTriagem neonatal.Sickle cell anemia is a genetic disease, transmitted by an autosomal recessive inheritance, represented by the existence of sickle-shaped erythrocytes, and highly prevalent in Brazil. Carriers of this pathology are asymptomatic in the first six months of life. Early diagnosis is achieved through neonatal screening, allowing the monitoring of patients before the manifestations and symptoms and, with this, the prevention of possible sequelae and complications. This study was carried out through a qualitative and quantitative bibliographic research, aiming to demonstrate, point out and correlate the main characteristics of this pathology with early diagnosis. Highlighting the main points of articles related to sickle cell anemia and its complications, using national and international publications, from the databases: SCIELO (Scientific Electronic Library Online), PubMed, Academic Google and VHL, in which 21 works were part of the construction of the results. Among these, 4 were found on PubMed, 9 on Sciello,7 on Google Scholar and 1 on the BVS platform. Responding to the objectives described, we can conclude that early diagnosis is essential, as the sooner sickle cell anemia is detected, there is more chance that the patient's quality and life expectancy will increase, with that the neonatal screening plays a fundamental role in this detection.La anemia drepanocítica es una enfermedad genética, transmitida por herencia autosómica recesiva, representada por la existencia de eritrocitos falciformes, y de alta prevalencia en Brasil. Los portadores de esta patología se encuentran asintomáticos en los primeros seis meses de vida. El diagnóstico precoz se logra mediante el cribado neonatal, permitiendo el seguimiento de los pacientes ante de las manifestaciones y síntomas y, con ello, la prevención de posibles secuelas y complicaciones. Este estudio se realizó mediante una investigación bibliográfica cualitativa y cuantitativa, con el objetivo de demostrar, señalar y correlacionar las principales características de esta patología con el diagnóstico precoz. Destacando los principales puntos de los artículos relacionados con la anemia falciforme y sus complicaciones, utilizando publicaciones nacionales e internacionales, de las bases de datos: SCIELO (Scientific Electronic Library Online), PubMed, Academic Google y VHL, en los que 21 trabajos formaron parte de la construcción de los resultados. Entre estos, 4 se encontraron en PubMed, 9 en Sciello, 7 en Google Scholar y 1 en la plataforma BVS. Respondiendo a los objetivos descritos, podemos concluir que el diagnóstico precoz es fundamental, ya que cuanto antes se detecte la anemia falciforme hay más posibilidades de que aumente la calidad y esperanza de vida del paciente, por lo que el cribado neonatal juega un papel fundamental en esta detección.Anemia falciforme é uma doença genética, transmitida por uma herança autossômica recessiva, representada pela existência de eritrócitos em forma de foice, e de grande prevalência no Brasil. Os portadores dessa patologia são assintomáticos nos primeiros seis meses de vida. O diagnóstico precoce dá-se através da triagem neonatal, permitindo o acompanhamento dos pacientes antes das manifestações e da sintomatologia e, com isto, a prevenção das possíveis sequelas e complicações. Este estudo foi realizado por meio de uma pesquisa bibliográfica qualitativa e quantitativa, tendo como objetivo demonstrar, apontar e correlacionar as principais características dessa patologia com o diagnóstico precoce. Destacando os principais pontos dos artigos relacionados a anemia falciforme e suas complicações, utilizando publicações nacionais e internacionais, das bases de dados: SCIELO (Scientific Electronic Library Online), PubMed, Google Acadêmico e BVS, no qual 21 trabalhos fizeram parte da construção dos resultados. Entre esses, 4 foram achados no PubMed, 9 no Sciello,7 no Google Acadêmico e 1 na plataforma BVS. Respondendo aos objetivos descritos, podemos concluir que o diagnóstico precoce é imprescindível, pois o quanto antes a anemia falciforme for detectada, há mais chances da qualidade e expectativa de vida do paciente aumentar, com isso a triagem neonatal tem um papel fundamental para esta detecção.Research, Society and Development2021-07-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1753910.33448/rsd-v10i8.17539Research, Society and Development; Vol. 10 No. 8; e38110817539Research, Society and Development; Vol. 10 Núm. 8; e38110817539Research, Society and Development; v. 10 n. 8; e381108175392525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/17539/15599Copyright (c) 2021 Carolina Dias Reis; Maisa de Lima Barbosa; Manoele Sousa Araújo; Murilo Tavares Amorim; Michele Amaral da Silveirahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessReis, Carolina DiasBarbosa, Maisa de Lima Araújo, Manoele Sousa Amorim, Murilo TavaresSilveira, Michele Amaral da2021-08-21T18:46:59Zoai:ojs.pkp.sfu.ca:article/17539Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:37:51.661906Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia La Importancia del Cribado Neonatal para la Detección Precoz de la Anemia Falciforme A Importância da Triagem Neonatal para a Detecção Precoce da Anemia Falciforme |
title |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia |
spellingShingle |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia Reis, Carolina Dias Hemoglobin S Sickle Cell Anemia Neonatal screening. Hemoglobina S Anemia de células falciformes Cribado neonatal. Hemoglobina S Anemia Falciforme Triagem neonatal. |
title_short |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia |
title_full |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia |
title_fullStr |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia |
title_full_unstemmed |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia |
title_sort |
The Importance of Neonatal Screening for the Early Detection of Sickle Cell Anemia |
author |
Reis, Carolina Dias |
author_facet |
Reis, Carolina Dias Barbosa, Maisa de Lima Araújo, Manoele Sousa Amorim, Murilo Tavares Silveira, Michele Amaral da |
author_role |
author |
author2 |
Barbosa, Maisa de Lima Araújo, Manoele Sousa Amorim, Murilo Tavares Silveira, Michele Amaral da |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Reis, Carolina Dias Barbosa, Maisa de Lima Araújo, Manoele Sousa Amorim, Murilo Tavares Silveira, Michele Amaral da |
dc.subject.por.fl_str_mv |
Hemoglobin S Sickle Cell Anemia Neonatal screening. Hemoglobina S Anemia de células falciformes Cribado neonatal. Hemoglobina S Anemia Falciforme Triagem neonatal. |
topic |
Hemoglobin S Sickle Cell Anemia Neonatal screening. Hemoglobina S Anemia de células falciformes Cribado neonatal. Hemoglobina S Anemia Falciforme Triagem neonatal. |
description |
Sickle cell anemia is a genetic disease, transmitted by an autosomal recessive inheritance, represented by the existence of sickle-shaped erythrocytes, and highly prevalent in Brazil. Carriers of this pathology are asymptomatic in the first six months of life. Early diagnosis is achieved through neonatal screening, allowing the monitoring of patients before the manifestations and symptoms and, with this, the prevention of possible sequelae and complications. This study was carried out through a qualitative and quantitative bibliographic research, aiming to demonstrate, point out and correlate the main characteristics of this pathology with early diagnosis. Highlighting the main points of articles related to sickle cell anemia and its complications, using national and international publications, from the databases: SCIELO (Scientific Electronic Library Online), PubMed, Academic Google and VHL, in which 21 works were part of the construction of the results. Among these, 4 were found on PubMed, 9 on Sciello,7 on Google Scholar and 1 on the BVS platform. Responding to the objectives described, we can conclude that early diagnosis is essential, as the sooner sickle cell anemia is detected, there is more chance that the patient's quality and life expectancy will increase, with that the neonatal screening plays a fundamental role in this detection. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-07-14 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/17539 10.33448/rsd-v10i8.17539 |
url |
https://rsdjournal.org/index.php/rsd/article/view/17539 |
identifier_str_mv |
10.33448/rsd-v10i8.17539 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/17539/15599 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 8; e38110817539 Research, Society and Development; Vol. 10 Núm. 8; e38110817539 Research, Society and Development; v. 10 n. 8; e38110817539 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052752090628096 |