Development of a pill based on the essential oil of Lippia alba

Detalhes bibliográficos
Autor(a) principal: Silva, Alan Rodrigues da
Data de Publicação: 2020
Outros Autores: Lima, Leandro Pereira, Pazini, Charlie Pinheiro, Silva, Camila de Lima, Andrade, Thais Maria Sousa, Barros, Lissandra de Sousa Rocha, Sousa, Lucas de Freitas Leite de, Soares, Fabiana Pereira, Silva, Angelo Roncalli Alves e
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/3973
Resumo: The lemongrass (Lippia alba quimiotipo II; Verbenaceae), a plant species that is part of the list of medicinal plants of the program Live Pharmacy of Ceará, has in its leaves essential oil rich in citral, which accounts for its anxiolytic property. The accomplishment of the present research will aim at the implementation of a new pharmaceutical form based on lemongrass in “Farmácias Vivas” that can be used for the treatment of anxiety. This oil will be obtained by hydrodistillation method. The base of the tablet will consist of lactose, cellulose, alcohol, 10% starch solution and L. alba essential oil. The granulate was evaluated by the apparent density, compacted density, Hausner Ratio, Carr Index, resting angle, flow velocity, organoleptic property and humidity. The obtained mixture presents adequate flowability according to the analysis parameters. The tablet was evaluated by weight average, hardness, friability, disintegration and thin layer chromatography.
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spelling Development of a pill based on the essential oil of Lippia albaDesarrollo de la tableta a base de aceite esencial de Lippia albaDesenvolvimento de comprimido a base do óleo essencial de Lippia albaErva-cidreiraComprimidoAnsiolítico.LemongrassTabletAnxiolytic.LemongrassTabletaAnsiolítico.The lemongrass (Lippia alba quimiotipo II; Verbenaceae), a plant species that is part of the list of medicinal plants of the program Live Pharmacy of Ceará, has in its leaves essential oil rich in citral, which accounts for its anxiolytic property. The accomplishment of the present research will aim at the implementation of a new pharmaceutical form based on lemongrass in “Farmácias Vivas” that can be used for the treatment of anxiety. This oil will be obtained by hydrodistillation method. The base of the tablet will consist of lactose, cellulose, alcohol, 10% starch solution and L. alba essential oil. The granulate was evaluated by the apparent density, compacted density, Hausner Ratio, Carr Index, resting angle, flow velocity, organoleptic property and humidity. The obtained mixture presents adequate flowability according to the analysis parameters. The tablet was evaluated by weight average, hardness, friability, disintegration and thin layer chromatography.La hierba de limón (Lippia alba quimiotipo II; Verbenaceae), una especie de planta que forma parte de la lista de plantas medicinales del programa Farmacia en vivo de Ceará, tiene en sus hojas un aceite esencial rico en citral, lo que explica su propiedad ansiolítica. La realización de la presente investigación tendrá como objetivo la implementación de una nueva forma farmacéutica basada en limoncillo en “Farmácias Vivas” que puede usarse para el tratamiento de la ansiedad. Este aceite se obtendrá por método de hidrodestilación. La base de la tableta consistirá en lactosa, celulosa, alcohol, solución de almidón al 10% y aceite esencial de L. alba. El granulado se evaluó por la densidad aparente, la densidad compactada, la relación de Hausner, el índice de Carr, el ángulo de reposo, la velocidad de flujo, la propiedad organoléptica y la humedad. La mezcla obtenida presenta una capacidad de flujo adecuada de acuerdo con los parámetros de análisis. La tableta se evaluó por promedio de peso, dureza, friabilidad, desintegración y cromatografía en capa fina.A erva-cidreira (Lippia alba quimiotipo II; Verbenaceae), espécie vegetal que faz parte do elenco de plantas medicinais do programa Farmácia Viva do Ceará, possui em suas folhas óleo essencial rico em citral, que responde pela sua propriedade ansiolítica. A realização da presente pesquisa objetivou a implementação de uma nova forma farmacêutica à base de erva cidreira em farmácias vivas, que possa ser utilizada para o tratamento da ansiedade. O óleo essencial foi obtido por hidrodestilação. A base do comprimido se constituiu em lactose, celulose, álcool, solução de amido a 10% e óleo essencial de L. alba. O granulado foi avaliado através da densidade aparente, densidade compactada, Proporção de Hausner, Índice de Carr, ângulo de repouso, velocidade de escoamento, propriedade organoléptica e umidade. A mistura obtida apresentou fluxibilidade adequada de acordo com os parâmetros de análise. O comprimido foi avaliado através do peso médio, dureza, friabilidade, desintegração e cromatografia em camada delgada.Research, Society and Development2020-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/397310.33448/rsd-v9i7.3973Research, Society and Development; Vol. 9 No. 7; e118973973Research, Society and Development; Vol. 9 Núm. 7; e118973973Research, Society and Development; v. 9 n. 7; e1189739732525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/3973/3256Copyright (c) 2020 Alan Rodrigues da Silva, Leandro Pereira Lima, Charlie Pinheiro Pazini, Camila de Lima Silva, Thais Maria Sousa Andrade, Lissandra de Sousa Rocha Barros, Lucas de Freitas Leite de Sousa, Fabiana Pereira Soares, Angelo Roncalli Alves e Silvainfo:eu-repo/semantics/openAccessSilva, Alan Rodrigues daLima, Leandro PereiraPazini, Charlie PinheiroSilva, Camila de LimaAndrade, Thais Maria SousaBarros, Lissandra de Sousa RochaSousa, Lucas de Freitas Leite deSoares, Fabiana PereiraSilva, Angelo Roncalli Alves e2020-08-20T18:05:03Zoai:ojs.pkp.sfu.ca:article/3973Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:27:59.236687Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Development of a pill based on the essential oil of Lippia alba
Desarrollo de la tableta a base de aceite esencial de Lippia alba
Desenvolvimento de comprimido a base do óleo essencial de Lippia alba
title Development of a pill based on the essential oil of Lippia alba
spellingShingle Development of a pill based on the essential oil of Lippia alba
Silva, Alan Rodrigues da
Erva-cidreira
Comprimido
Ansiolítico.
Lemongrass
Tablet
Anxiolytic.
Lemongrass
Tableta
Ansiolítico.
title_short Development of a pill based on the essential oil of Lippia alba
title_full Development of a pill based on the essential oil of Lippia alba
title_fullStr Development of a pill based on the essential oil of Lippia alba
title_full_unstemmed Development of a pill based on the essential oil of Lippia alba
title_sort Development of a pill based on the essential oil of Lippia alba
author Silva, Alan Rodrigues da
author_facet Silva, Alan Rodrigues da
Lima, Leandro Pereira
Pazini, Charlie Pinheiro
Silva, Camila de Lima
Andrade, Thais Maria Sousa
Barros, Lissandra de Sousa Rocha
Sousa, Lucas de Freitas Leite de
Soares, Fabiana Pereira
Silva, Angelo Roncalli Alves e
author_role author
author2 Lima, Leandro Pereira
Pazini, Charlie Pinheiro
Silva, Camila de Lima
Andrade, Thais Maria Sousa
Barros, Lissandra de Sousa Rocha
Sousa, Lucas de Freitas Leite de
Soares, Fabiana Pereira
Silva, Angelo Roncalli Alves e
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Alan Rodrigues da
Lima, Leandro Pereira
Pazini, Charlie Pinheiro
Silva, Camila de Lima
Andrade, Thais Maria Sousa
Barros, Lissandra de Sousa Rocha
Sousa, Lucas de Freitas Leite de
Soares, Fabiana Pereira
Silva, Angelo Roncalli Alves e
dc.subject.por.fl_str_mv Erva-cidreira
Comprimido
Ansiolítico.
Lemongrass
Tablet
Anxiolytic.
Lemongrass
Tableta
Ansiolítico.
topic Erva-cidreira
Comprimido
Ansiolítico.
Lemongrass
Tablet
Anxiolytic.
Lemongrass
Tableta
Ansiolítico.
description The lemongrass (Lippia alba quimiotipo II; Verbenaceae), a plant species that is part of the list of medicinal plants of the program Live Pharmacy of Ceará, has in its leaves essential oil rich in citral, which accounts for its anxiolytic property. The accomplishment of the present research will aim at the implementation of a new pharmaceutical form based on lemongrass in “Farmácias Vivas” that can be used for the treatment of anxiety. This oil will be obtained by hydrodistillation method. The base of the tablet will consist of lactose, cellulose, alcohol, 10% starch solution and L. alba essential oil. The granulate was evaluated by the apparent density, compacted density, Hausner Ratio, Carr Index, resting angle, flow velocity, organoleptic property and humidity. The obtained mixture presents adequate flowability according to the analysis parameters. The tablet was evaluated by weight average, hardness, friability, disintegration and thin layer chromatography.
publishDate 2020
dc.date.none.fl_str_mv 2020-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/3973
10.33448/rsd-v9i7.3973
url https://rsdjournal.org/index.php/rsd/article/view/3973
identifier_str_mv 10.33448/rsd-v9i7.3973
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/3973/3256
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 7; e118973973
Research, Society and Development; Vol. 9 Núm. 7; e118973973
Research, Society and Development; v. 9 n. 7; e118973973
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052778391011328

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