Medicinal use of cannabis in the treatment of epilepsy

Detalhes bibliográficos
Autor(a) principal: Silva, Ana Karolaynne Soares da
Data de Publicação: 2022
Outros Autores: Vasconcelos, Tibério Cesar Lima de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/30471
Resumo: Epilepsy is a neurological disease, characterized by excessive neuronal activity, the seizures. Studies show that the incidence of symptoms is higher in the first year of life, and the approximate number of patients affected in the world is 70 million people. Objective: The objective of this present work is to investigate the medicinal use of cannabis, as well as to analyze its safety and efficacy in the treatment of epilepsy. Methodology: To make this possible, a systematic review was carried out in such databases: ScienceDirect, Virtual Health Library – VHL and Pubmed, using the descriptors cannabis and epilepsy, cannabis and pharmacology, cannabis treatment, epilepsy. Results: Drugs that are used as a form of treatment are effective in about 70% of cases, with the remaining 30% presenting a refractory form to treatment. These circumstances generate fervor in the development of effective therapeutic solutions in the treatment of these refractory cases, in this way, cannabis comes to gain space, when it has several therapeutic functions, such as reducing the frequency of seizures, which is of great value for such patients. Conclusion: From the data collection, the conclusion is that the use of cannabis has a promising effect in the treatment of epilepsy, when compared to conventional pharmacotherapy, even with some side effects that are somewhat acceptable. It is of considerable importance to emphasize that because it is an extract that originates from a plant seen as a psychoactive drug, its label becomes valuable for scientific advancement, requiring further analysis and future studies.
id UNIFEI_1580db1a7b427df077d65d4061ca6539
oai_identifier_str oai:ojs.pkp.sfu.ca:article/30471
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Medicinal use of cannabis in the treatment of epilepsyUso medicinal del cannabis en el tratamiento de la epilepsiaUso medicinal da cannabis no tratamento da epilepsiaEpilepsiaFarmacologíaCannabis SativaTratamientoEnseñanza en salud.EpilepsyPharmacologyCannabis SativaTreatmentHealth teaching.EpilepsiaFarmacologiaCannabis SativaTratamentoEnsino em saúde.Epilepsy is a neurological disease, characterized by excessive neuronal activity, the seizures. Studies show that the incidence of symptoms is higher in the first year of life, and the approximate number of patients affected in the world is 70 million people. Objective: The objective of this present work is to investigate the medicinal use of cannabis, as well as to analyze its safety and efficacy in the treatment of epilepsy. Methodology: To make this possible, a systematic review was carried out in such databases: ScienceDirect, Virtual Health Library – VHL and Pubmed, using the descriptors cannabis and epilepsy, cannabis and pharmacology, cannabis treatment, epilepsy. Results: Drugs that are used as a form of treatment are effective in about 70% of cases, with the remaining 30% presenting a refractory form to treatment. These circumstances generate fervor in the development of effective therapeutic solutions in the treatment of these refractory cases, in this way, cannabis comes to gain space, when it has several therapeutic functions, such as reducing the frequency of seizures, which is of great value for such patients. Conclusion: From the data collection, the conclusion is that the use of cannabis has a promising effect in the treatment of epilepsy, when compared to conventional pharmacotherapy, even with some side effects that are somewhat acceptable. It is of considerable importance to emphasize that because it is an extract that originates from a plant seen as a psychoactive drug, its label becomes valuable for scientific advancement, requiring further analysis and future studies.La epilepsia es una enfermedad neurológica, caracterizada por una actividad neuronal excesiva, las convulsiones. Los estudios muestran que la incidencia de síntomas es mayor en el primer año de vida, y el número aproximado de pacientes afectados en el mundo es de 70 millones de personas. Objetivo: El objetivo del presente trabajo es investigar el uso medicinal del cannabis, así como analizar su seguridad y eficacia en el tratamiento de la epilepsia. Metodología: Para posibilitar esto, se realizó una revisión sistemática en dichas bases de datos: ScienceDirect, Biblioteca Virtual en Salud – BVS y Pubmed, utilizando los descriptores cannabis y epilepsia, cannabis y farmacología, tratamiento con cannabis, epilepsia. Resultados: Los fármacos que se utilizan como forma de tratamiento son efectivos en alrededor del 70% de los casos, presentando el 30% restante una forma refractaria al tratamiento. Estas circunstancias generan fervor en el desarrollo de soluciones terapéuticas efectivas en el tratamiento de estos casos refractarios, de esta forma, el cannabis viene a ganar espacio, cuando tiene varias funciones terapéuticas, como la reducción de la frecuencia de las convulsiones, lo cual es de gran valor para tales pacientes. Conclusión: A partir de la recopilación de datos, se concluye que el uso de cannabis tiene un efecto prometedor en el tratamiento de la epilepsia, en comparación con la farmacoterapia convencional, incluso con algunos efectos secundarios que son algo aceptables. Es de suma importancia resaltar que por tratarse de un extracto que se origina de una planta vista como droga psicoactiva, su etiqueta se vuelve valiosa para el avance científico, requiriendo mayores análisis y estudios futuros.A epilepsia é uma doença neurológica, caracterizada por atividade neuronal excessiva, as crises convulsivas. Estudos comprovam que a incidência dos sintomas é maior no primeiro ano de vida, e o número aproximado de pacientes acometidos no mundo é de 70 milhões de pessoas. Objetivo: O objetivo desse presente trabalho é investigar o uso medicinal da cannabis, assim como analisar sua segurança e eficácia no tratamento da epilepsia. Metodologia: Para que isso fosse possível, foi realizada uma revisão sistemática, em tais bases de dados: ScienceDirect, Biblioteca Virtual de Saúde – BVS e Pubmed, utilizando os descritores cannabis e epilepsia, cannabis e farmacologia. Resultados: Os fármacos que são utilizados como forma de tratamento têm eficácia em cerca de 70% dos casos, onde os 30% restantes apresentam uma forma refratária ao tratamento. Estas circunstâncias geram fervor no desenvolvimento de efetivas soluções terapêuticas no tratamento desses casos refratários, dessa forma, a cannabis chega a ganhar espaço, quando apresenta várias funções terapêuticas, como a diminuição da frequência das convulsões, que é de grande valia para tais pacientes. Conclusão: A partir do recolhimento de dados, a conclusão é que o uso da cannabis tem efeito promissor no tratamento da epilepsia, quando comparado à convencional farmacoterapia, mesmo acompanhando alguns efeitos colaterais que são de certa forma aceitáveis. É de considerável importância ressaltar que por se tratar de um extrato que possui origem de uma planta vista como droga psicoativa, seu rótulo torna-se valioso para o avanço científico, necessitando de mais análises e estudos futuros.Research, Society and Development2022-06-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3047110.33448/rsd-v11i8.30471Research, Society and Development; Vol. 11 No. 8; e17811830471Research, Society and Development; Vol. 11 Núm. 8; e17811830471Research, Society and Development; v. 11 n. 8; e178118304712525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/30471/26389Copyright (c) 2022 Ana Karolaynne Soares da Silva; Tibério Cesar Lima de Vasconceloshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Ana Karolaynne Soares daVasconcelos, Tibério Cesar Lima de 2022-07-01T13:34:06Zoai:ojs.pkp.sfu.ca:article/30471Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:47:12.685230Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Medicinal use of cannabis in the treatment of epilepsy
Uso medicinal del cannabis en el tratamiento de la epilepsia
Uso medicinal da cannabis no tratamento da epilepsia
title Medicinal use of cannabis in the treatment of epilepsy
spellingShingle Medicinal use of cannabis in the treatment of epilepsy
Silva, Ana Karolaynne Soares da
Epilepsia
Farmacología
Cannabis Sativa
Tratamiento
Enseñanza en salud.
Epilepsy
Pharmacology
Cannabis Sativa
Treatment
Health teaching.
Epilepsia
Farmacologia
Cannabis Sativa
Tratamento
Ensino em saúde.
title_short Medicinal use of cannabis in the treatment of epilepsy
title_full Medicinal use of cannabis in the treatment of epilepsy
title_fullStr Medicinal use of cannabis in the treatment of epilepsy
title_full_unstemmed Medicinal use of cannabis in the treatment of epilepsy
title_sort Medicinal use of cannabis in the treatment of epilepsy
author Silva, Ana Karolaynne Soares da
author_facet Silva, Ana Karolaynne Soares da
Vasconcelos, Tibério Cesar Lima de
author_role author
author2 Vasconcelos, Tibério Cesar Lima de
author2_role author
dc.contributor.author.fl_str_mv Silva, Ana Karolaynne Soares da
Vasconcelos, Tibério Cesar Lima de
dc.subject.por.fl_str_mv Epilepsia
Farmacología
Cannabis Sativa
Tratamiento
Enseñanza en salud.
Epilepsy
Pharmacology
Cannabis Sativa
Treatment
Health teaching.
Epilepsia
Farmacologia
Cannabis Sativa
Tratamento
Ensino em saúde.
topic Epilepsia
Farmacología
Cannabis Sativa
Tratamiento
Enseñanza en salud.
Epilepsy
Pharmacology
Cannabis Sativa
Treatment
Health teaching.
Epilepsia
Farmacologia
Cannabis Sativa
Tratamento
Ensino em saúde.
description Epilepsy is a neurological disease, characterized by excessive neuronal activity, the seizures. Studies show that the incidence of symptoms is higher in the first year of life, and the approximate number of patients affected in the world is 70 million people. Objective: The objective of this present work is to investigate the medicinal use of cannabis, as well as to analyze its safety and efficacy in the treatment of epilepsy. Methodology: To make this possible, a systematic review was carried out in such databases: ScienceDirect, Virtual Health Library – VHL and Pubmed, using the descriptors cannabis and epilepsy, cannabis and pharmacology, cannabis treatment, epilepsy. Results: Drugs that are used as a form of treatment are effective in about 70% of cases, with the remaining 30% presenting a refractory form to treatment. These circumstances generate fervor in the development of effective therapeutic solutions in the treatment of these refractory cases, in this way, cannabis comes to gain space, when it has several therapeutic functions, such as reducing the frequency of seizures, which is of great value for such patients. Conclusion: From the data collection, the conclusion is that the use of cannabis has a promising effect in the treatment of epilepsy, when compared to conventional pharmacotherapy, even with some side effects that are somewhat acceptable. It is of considerable importance to emphasize that because it is an extract that originates from a plant seen as a psychoactive drug, its label becomes valuable for scientific advancement, requiring further analysis and future studies.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-14
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/30471
10.33448/rsd-v11i8.30471
url https://rsdjournal.org/index.php/rsd/article/view/30471
identifier_str_mv 10.33448/rsd-v11i8.30471
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/30471/26389
dc.rights.driver.fl_str_mv Copyright (c) 2022 Ana Karolaynne Soares da Silva; Tibério Cesar Lima de Vasconcelos
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Ana Karolaynne Soares da Silva; Tibério Cesar Lima de Vasconcelos
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 8; e17811830471
Research, Society and Development; Vol. 11 Núm. 8; e17811830471
Research, Society and Development; v. 11 n. 8; e17811830471
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052827278770176