Medicinal use of cannabis in the treatment of epilepsy
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Data de Publicação: | 2022 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/30471 |
Resumo: | Epilepsy is a neurological disease, characterized by excessive neuronal activity, the seizures. Studies show that the incidence of symptoms is higher in the first year of life, and the approximate number of patients affected in the world is 70 million people. Objective: The objective of this present work is to investigate the medicinal use of cannabis, as well as to analyze its safety and efficacy in the treatment of epilepsy. Methodology: To make this possible, a systematic review was carried out in such databases: ScienceDirect, Virtual Health Library – VHL and Pubmed, using the descriptors cannabis and epilepsy, cannabis and pharmacology, cannabis treatment, epilepsy. Results: Drugs that are used as a form of treatment are effective in about 70% of cases, with the remaining 30% presenting a refractory form to treatment. These circumstances generate fervor in the development of effective therapeutic solutions in the treatment of these refractory cases, in this way, cannabis comes to gain space, when it has several therapeutic functions, such as reducing the frequency of seizures, which is of great value for such patients. Conclusion: From the data collection, the conclusion is that the use of cannabis has a promising effect in the treatment of epilepsy, when compared to conventional pharmacotherapy, even with some side effects that are somewhat acceptable. It is of considerable importance to emphasize that because it is an extract that originates from a plant seen as a psychoactive drug, its label becomes valuable for scientific advancement, requiring further analysis and future studies. |
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Medicinal use of cannabis in the treatment of epilepsyUso medicinal del cannabis en el tratamiento de la epilepsiaUso medicinal da cannabis no tratamento da epilepsiaEpilepsiaFarmacologíaCannabis SativaTratamientoEnseñanza en salud.EpilepsyPharmacologyCannabis SativaTreatmentHealth teaching.EpilepsiaFarmacologiaCannabis SativaTratamentoEnsino em saúde.Epilepsy is a neurological disease, characterized by excessive neuronal activity, the seizures. Studies show that the incidence of symptoms is higher in the first year of life, and the approximate number of patients affected in the world is 70 million people. Objective: The objective of this present work is to investigate the medicinal use of cannabis, as well as to analyze its safety and efficacy in the treatment of epilepsy. Methodology: To make this possible, a systematic review was carried out in such databases: ScienceDirect, Virtual Health Library – VHL and Pubmed, using the descriptors cannabis and epilepsy, cannabis and pharmacology, cannabis treatment, epilepsy. Results: Drugs that are used as a form of treatment are effective in about 70% of cases, with the remaining 30% presenting a refractory form to treatment. These circumstances generate fervor in the development of effective therapeutic solutions in the treatment of these refractory cases, in this way, cannabis comes to gain space, when it has several therapeutic functions, such as reducing the frequency of seizures, which is of great value for such patients. Conclusion: From the data collection, the conclusion is that the use of cannabis has a promising effect in the treatment of epilepsy, when compared to conventional pharmacotherapy, even with some side effects that are somewhat acceptable. It is of considerable importance to emphasize that because it is an extract that originates from a plant seen as a psychoactive drug, its label becomes valuable for scientific advancement, requiring further analysis and future studies.La epilepsia es una enfermedad neurológica, caracterizada por una actividad neuronal excesiva, las convulsiones. Los estudios muestran que la incidencia de síntomas es mayor en el primer año de vida, y el número aproximado de pacientes afectados en el mundo es de 70 millones de personas. Objetivo: El objetivo del presente trabajo es investigar el uso medicinal del cannabis, así como analizar su seguridad y eficacia en el tratamiento de la epilepsia. Metodología: Para posibilitar esto, se realizó una revisión sistemática en dichas bases de datos: ScienceDirect, Biblioteca Virtual en Salud – BVS y Pubmed, utilizando los descriptores cannabis y epilepsia, cannabis y farmacología, tratamiento con cannabis, epilepsia. Resultados: Los fármacos que se utilizan como forma de tratamiento son efectivos en alrededor del 70% de los casos, presentando el 30% restante una forma refractaria al tratamiento. Estas circunstancias generan fervor en el desarrollo de soluciones terapéuticas efectivas en el tratamiento de estos casos refractarios, de esta forma, el cannabis viene a ganar espacio, cuando tiene varias funciones terapéuticas, como la reducción de la frecuencia de las convulsiones, lo cual es de gran valor para tales pacientes. Conclusión: A partir de la recopilación de datos, se concluye que el uso de cannabis tiene un efecto prometedor en el tratamiento de la epilepsia, en comparación con la farmacoterapia convencional, incluso con algunos efectos secundarios que son algo aceptables. Es de suma importancia resaltar que por tratarse de un extracto que se origina de una planta vista como droga psicoactiva, su etiqueta se vuelve valiosa para el avance científico, requiriendo mayores análisis y estudios futuros.A epilepsia é uma doença neurológica, caracterizada por atividade neuronal excessiva, as crises convulsivas. Estudos comprovam que a incidência dos sintomas é maior no primeiro ano de vida, e o número aproximado de pacientes acometidos no mundo é de 70 milhões de pessoas. Objetivo: O objetivo desse presente trabalho é investigar o uso medicinal da cannabis, assim como analisar sua segurança e eficácia no tratamento da epilepsia. Metodologia: Para que isso fosse possível, foi realizada uma revisão sistemática, em tais bases de dados: ScienceDirect, Biblioteca Virtual de Saúde – BVS e Pubmed, utilizando os descritores cannabis e epilepsia, cannabis e farmacologia. Resultados: Os fármacos que são utilizados como forma de tratamento têm eficácia em cerca de 70% dos casos, onde os 30% restantes apresentam uma forma refratária ao tratamento. Estas circunstâncias geram fervor no desenvolvimento de efetivas soluções terapêuticas no tratamento desses casos refratários, dessa forma, a cannabis chega a ganhar espaço, quando apresenta várias funções terapêuticas, como a diminuição da frequência das convulsões, que é de grande valia para tais pacientes. Conclusão: A partir do recolhimento de dados, a conclusão é que o uso da cannabis tem efeito promissor no tratamento da epilepsia, quando comparado à convencional farmacoterapia, mesmo acompanhando alguns efeitos colaterais que são de certa forma aceitáveis. É de considerável importância ressaltar que por se tratar de um extrato que possui origem de uma planta vista como droga psicoativa, seu rótulo torna-se valioso para o avanço científico, necessitando de mais análises e estudos futuros.Research, Society and Development2022-06-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3047110.33448/rsd-v11i8.30471Research, Society and Development; Vol. 11 No. 8; e17811830471Research, Society and Development; Vol. 11 Núm. 8; e17811830471Research, Society and Development; v. 11 n. 8; e178118304712525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/30471/26389Copyright (c) 2022 Ana Karolaynne Soares da Silva; Tibério Cesar Lima de Vasconceloshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Ana Karolaynne Soares daVasconcelos, Tibério Cesar Lima de 2022-07-01T13:34:06Zoai:ojs.pkp.sfu.ca:article/30471Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:47:12.685230Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Medicinal use of cannabis in the treatment of epilepsy Uso medicinal del cannabis en el tratamiento de la epilepsia Uso medicinal da cannabis no tratamento da epilepsia |
title |
Medicinal use of cannabis in the treatment of epilepsy |
spellingShingle |
Medicinal use of cannabis in the treatment of epilepsy Silva, Ana Karolaynne Soares da Epilepsia Farmacología Cannabis Sativa Tratamiento Enseñanza en salud. Epilepsy Pharmacology Cannabis Sativa Treatment Health teaching. Epilepsia Farmacologia Cannabis Sativa Tratamento Ensino em saúde. |
title_short |
Medicinal use of cannabis in the treatment of epilepsy |
title_full |
Medicinal use of cannabis in the treatment of epilepsy |
title_fullStr |
Medicinal use of cannabis in the treatment of epilepsy |
title_full_unstemmed |
Medicinal use of cannabis in the treatment of epilepsy |
title_sort |
Medicinal use of cannabis in the treatment of epilepsy |
author |
Silva, Ana Karolaynne Soares da |
author_facet |
Silva, Ana Karolaynne Soares da Vasconcelos, Tibério Cesar Lima de |
author_role |
author |
author2 |
Vasconcelos, Tibério Cesar Lima de |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Silva, Ana Karolaynne Soares da Vasconcelos, Tibério Cesar Lima de |
dc.subject.por.fl_str_mv |
Epilepsia Farmacología Cannabis Sativa Tratamiento Enseñanza en salud. Epilepsy Pharmacology Cannabis Sativa Treatment Health teaching. Epilepsia Farmacologia Cannabis Sativa Tratamento Ensino em saúde. |
topic |
Epilepsia Farmacología Cannabis Sativa Tratamiento Enseñanza en salud. Epilepsy Pharmacology Cannabis Sativa Treatment Health teaching. Epilepsia Farmacologia Cannabis Sativa Tratamento Ensino em saúde. |
description |
Epilepsy is a neurological disease, characterized by excessive neuronal activity, the seizures. Studies show that the incidence of symptoms is higher in the first year of life, and the approximate number of patients affected in the world is 70 million people. Objective: The objective of this present work is to investigate the medicinal use of cannabis, as well as to analyze its safety and efficacy in the treatment of epilepsy. Methodology: To make this possible, a systematic review was carried out in such databases: ScienceDirect, Virtual Health Library – VHL and Pubmed, using the descriptors cannabis and epilepsy, cannabis and pharmacology, cannabis treatment, epilepsy. Results: Drugs that are used as a form of treatment are effective in about 70% of cases, with the remaining 30% presenting a refractory form to treatment. These circumstances generate fervor in the development of effective therapeutic solutions in the treatment of these refractory cases, in this way, cannabis comes to gain space, when it has several therapeutic functions, such as reducing the frequency of seizures, which is of great value for such patients. Conclusion: From the data collection, the conclusion is that the use of cannabis has a promising effect in the treatment of epilepsy, when compared to conventional pharmacotherapy, even with some side effects that are somewhat acceptable. It is of considerable importance to emphasize that because it is an extract that originates from a plant seen as a psychoactive drug, its label becomes valuable for scientific advancement, requiring further analysis and future studies. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-14 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/30471 10.33448/rsd-v11i8.30471 |
url |
https://rsdjournal.org/index.php/rsd/article/view/30471 |
identifier_str_mv |
10.33448/rsd-v11i8.30471 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/30471/26389 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Ana Karolaynne Soares da Silva; Tibério Cesar Lima de Vasconcelos https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Ana Karolaynne Soares da Silva; Tibério Cesar Lima de Vasconcelos https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 8; e17811830471 Research, Society and Development; Vol. 11 Núm. 8; e17811830471 Research, Society and Development; v. 11 n. 8; e17811830471 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052827278770176 |