Importance of immunohematological techniques in the blood transfusion process

Detalhes bibliográficos
Autor(a) principal: Mota, Lennara Pereira
Data de Publicação: 2020
Outros Autores: Kirchesch, Cryshna Letícia, Martins, Solange Avylla Santos, Figueiredo, Bruno Leonardo de Sousa, Souza, Daiane Borges, Silva, Esdras Andrade, Araújo, Valéria Pereira Barbosa da Silva, Linhares, Naine dos Santos, Figueira, Paulo Henrique Alves, Silva, Camila Maria Pinheiro de Mello e, Silva, Josemária Chaves Sipauba, Fernandes, Caroline França, Alves, Ana Beatriz Damasceno, Araujo, Andressa Fabianny de Sousa, Bálsamo, Ana Cândida Martins, Mesquita, Maxkson Messias de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/6625
Resumo: Transfusion therapy results in the transfusion of specific blood components, which the patient needs to replace, opposing the use of whole blood. This procedure aims to benefit several patients, and to optimize the stocks of blood banks. The presence of anti-erythrocyte antibodies in the serum of patients can cause hemolytic reactions. The identification of these antibodies is extremely necessary for the search for compatible blood components and, consequently, the prevention of transfusion reactions. The objective of this work is to describe the importance of pre-transfusion immunohematological techniques in the blood transfusion process. This is a qualitative bibliographic review based on scientific production based on studies already published. The decision to transfuse a patient must consider the risks and benefits and assess whether there is a real need for blood transfusion. The evaluation occurs through hemoglobin values ​​(for red blood cell transfusions) and platelet values ​​(for blood platelet transfusions) and the clinical aspects of the patient. The introduction of laboratory tests and better donor screening have significantly reduced mortality rates and risks of infections related to this procedure and the most frequent complications today are related to non-infectious causes. Patients who frequently perform blood transfusions may become sensitized, producing alloantibodies, due to the presence of anti-erythrocyte antigens present in the transfused blood bags. These patients have a greater risk of developing transfusion reactions, therefore, the importance of pre-transfusion immunohematological techniques whose main function is to track the presence of irregular antibodies in the recipients and find compatible bags for blood transfusion, decreasing the risk of transfusion reactions and increasing patient safety.
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spelling Importance of immunohematological techniques in the blood transfusion processImportancia de las técnicas inmunohematológicas en el proceso de transfusión de sangreImportância das técnicas imunohematológicas no processo de hemotransfusãoComponentes do SangueTransfusãoReação Transfusional.Componentes de la sangreTransfusiónReacción de transfusión.Blood componentsTransfusionTransfusion reaction.Transfusion therapy results in the transfusion of specific blood components, which the patient needs to replace, opposing the use of whole blood. This procedure aims to benefit several patients, and to optimize the stocks of blood banks. The presence of anti-erythrocyte antibodies in the serum of patients can cause hemolytic reactions. The identification of these antibodies is extremely necessary for the search for compatible blood components and, consequently, the prevention of transfusion reactions. The objective of this work is to describe the importance of pre-transfusion immunohematological techniques in the blood transfusion process. This is a qualitative bibliographic review based on scientific production based on studies already published. The decision to transfuse a patient must consider the risks and benefits and assess whether there is a real need for blood transfusion. The evaluation occurs through hemoglobin values ​​(for red blood cell transfusions) and platelet values ​​(for blood platelet transfusions) and the clinical aspects of the patient. The introduction of laboratory tests and better donor screening have significantly reduced mortality rates and risks of infections related to this procedure and the most frequent complications today are related to non-infectious causes. Patients who frequently perform blood transfusions may become sensitized, producing alloantibodies, due to the presence of anti-erythrocyte antigens present in the transfused blood bags. These patients have a greater risk of developing transfusion reactions, therefore, the importance of pre-transfusion immunohematological techniques whose main function is to track the presence of irregular antibodies in the recipients and find compatible bags for blood transfusion, decreasing the risk of transfusion reactions and increasing patient safety.La terapia de transfusión da como resultado la transfusión de componentes sanguíneos específicos, que el paciente necesita reemplazar, oponiéndose al uso de sangre completa. Este procedimiento tiene como objetivo beneficiar a varios pacientes y optimizar las reservas de bancos de sangre. La presencia de anticuerpos anti-eritrocitos en el suero de los pacientes puede causar reacciones hemolíticas. La identificación de estos anticuerpos es extremadamente necesaria para buscar componentes sanguíneos compatibles y, en consecuencia, para evitar reacciones a la transfusión. El objetivo de este trabajo es describir la importancia de las técnicas inmunohematológicas previas a la transfusión en el proceso de transfusión de sangre. Esta es una revisión bibliográfica cualitativa basada en la producción científica basada en estudios ya publicados. La decisión de transfundir a un paciente debe considerar los riesgos y beneficios y evaluar si existe una necesidad real de transfusión de sangre. La evaluación se realiza a través de los valores de hemoglobina (para transfusiones de glóbulos rojos) y valores de plaquetas (para transfusiones de concentrados de plaquetas) y los aspectos clínicos del paciente. La introducción de pruebas de laboratorio y una mejor detección de donantes han reducido significativamente las tasas de mortalidad y los riesgos de infecciones relacionadas con este procedimiento y las complicaciones más frecuentes en la actualidad están relacionadas con causas no infecciosas. Los pacientes que realizan transfusiones de sangre con frecuencia pueden sensibilizarse y producir aloanticuerpos, debido a la presencia de antígenos anti-eritrocitos presentes en las bolsas de sangre transfundidas. Estos pacientes tienen un mayor riesgo de desarrollar reacciones a la transfusión, por lo tanto, la importancia de las técnicas inmunohematológicas previas a la transfusión cuya función principal es rastrear la presencia de anticuerpos irregulares en los receptores y encontrar bolsas compatibles para la transfusión de sangre, disminuyendo el riesgo de reacciones a la transfusión y aumentando la seguridad del paciente.A Terapia Transfusional resulta na transfusão de componentes específicos do sangue, dos quais o paciente necessita repor, opondo-se a utilização de sangue total. Este procedimento visa o beneficio de vários pacientes, e a otimização dos estoques dos bancos de sangue. A presença de anticorpos antieritrocitários no soro de pacientes podem ocasionar reações hemolíticas. É extremamente necessária a identificação desses anticorpos para a busca de hemocomponentes compatíveis e consequentemente a prevenção de reações transfusionais. O objetivo deste trabalho é de descrever a importância das técnicas imunohematológicas pré transfusionais no processo de transfusão de hemocomponentes. Trata-se de uma revisão bibliográfica de caráter qualitativo que se baseia na produção científica a partir de estudos já publicados. A decisão de transfundir um paciente deve considerar os riscos e benefícios e avaliar se há realmente necessidade de uma hemotransfusão. A avaliação ocorre através dos valores de hemoglobina (para transfusões de concentrado de hemácias) e valores de plaquetas (para transfusões de concentrado de plaquetas) e os aspectos clínicos do paciente. A introdução de testes laboratoriais e uma melhor triagem dos doadores reduziram significativamente as taxas de mortalidade e riscos de infecções relacionadas a este procedimento e as complicações mais frequentes atualmente são relacionadas a causas não infecciosas. Pacientes que realizam transfusões sanguíneas com frequência podem sensibilizar-se, produzindo aloanticorpos, devido à presença de antígenos antieritrocitários presentes nas bolsas de sangue transfundidas. Esses pacientes apresentam um risco maior no desenvolvimento de reações transfusionais, por isso, a importância das técnicas imunohematológicas pré transfusionais que tem como função principal rastrear a presença de anticorpos irregulares nos receptores e encontrar bolsas compatíveis para a hemotransfusão, diminuindo o risco de reações transfusionais e aumentando a segurança do paciente. Research, Society and Development2020-08-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/662510.33448/rsd-v9i8.6625Research, Society and Development; Vol. 9 No. 8; e936986625Research, Society and Development; Vol. 9 Núm. 8; e936986625Research, Society and Development; v. 9 n. 8; e9369866252525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/6625/6033Copyright (c) 2020 Lennara Pereira Motahttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMota, Lennara PereiraKirchesch, Cryshna LetíciaMartins, Solange Avylla SantosFigueiredo, Bruno Leonardo de SousaSouza, Daiane BorgesSilva, Esdras AndradeAraújo, Valéria Pereira Barbosa da SilvaLinhares, Naine dos SantosFigueira, Paulo Henrique AlvesSilva, Camila Maria Pinheiro de Mello eSilva, Josemária Chaves SipaubaFernandes, Caroline FrançaAlves, Ana Beatriz DamascenoAraujo, Andressa Fabianny de SousaBálsamo, Ana Cândida MartinsMesquita, Maxkson Messias de2020-08-20T18:00:17Zoai:ojs.pkp.sfu.ca:article/6625Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:29:41.055245Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Importance of immunohematological techniques in the blood transfusion process
Importancia de las técnicas inmunohematológicas en el proceso de transfusión de sangre
Importância das técnicas imunohematológicas no processo de hemotransfusão
title Importance of immunohematological techniques in the blood transfusion process
spellingShingle Importance of immunohematological techniques in the blood transfusion process
Mota, Lennara Pereira
Componentes do Sangue
Transfusão
Reação Transfusional.
Componentes de la sangre
Transfusión
Reacción de transfusión.
Blood components
Transfusion
Transfusion reaction.
title_short Importance of immunohematological techniques in the blood transfusion process
title_full Importance of immunohematological techniques in the blood transfusion process
title_fullStr Importance of immunohematological techniques in the blood transfusion process
title_full_unstemmed Importance of immunohematological techniques in the blood transfusion process
title_sort Importance of immunohematological techniques in the blood transfusion process
author Mota, Lennara Pereira
author_facet Mota, Lennara Pereira
Kirchesch, Cryshna Letícia
Martins, Solange Avylla Santos
Figueiredo, Bruno Leonardo de Sousa
Souza, Daiane Borges
Silva, Esdras Andrade
Araújo, Valéria Pereira Barbosa da Silva
Linhares, Naine dos Santos
Figueira, Paulo Henrique Alves
Silva, Camila Maria Pinheiro de Mello e
Silva, Josemária Chaves Sipauba
Fernandes, Caroline França
Alves, Ana Beatriz Damasceno
Araujo, Andressa Fabianny de Sousa
Bálsamo, Ana Cândida Martins
Mesquita, Maxkson Messias de
author_role author
author2 Kirchesch, Cryshna Letícia
Martins, Solange Avylla Santos
Figueiredo, Bruno Leonardo de Sousa
Souza, Daiane Borges
Silva, Esdras Andrade
Araújo, Valéria Pereira Barbosa da Silva
Linhares, Naine dos Santos
Figueira, Paulo Henrique Alves
Silva, Camila Maria Pinheiro de Mello e
Silva, Josemária Chaves Sipauba
Fernandes, Caroline França
Alves, Ana Beatriz Damasceno
Araujo, Andressa Fabianny de Sousa
Bálsamo, Ana Cândida Martins
Mesquita, Maxkson Messias de
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mota, Lennara Pereira
Kirchesch, Cryshna Letícia
Martins, Solange Avylla Santos
Figueiredo, Bruno Leonardo de Sousa
Souza, Daiane Borges
Silva, Esdras Andrade
Araújo, Valéria Pereira Barbosa da Silva
Linhares, Naine dos Santos
Figueira, Paulo Henrique Alves
Silva, Camila Maria Pinheiro de Mello e
Silva, Josemária Chaves Sipauba
Fernandes, Caroline França
Alves, Ana Beatriz Damasceno
Araujo, Andressa Fabianny de Sousa
Bálsamo, Ana Cândida Martins
Mesquita, Maxkson Messias de
dc.subject.por.fl_str_mv Componentes do Sangue
Transfusão
Reação Transfusional.
Componentes de la sangre
Transfusión
Reacción de transfusión.
Blood components
Transfusion
Transfusion reaction.
topic Componentes do Sangue
Transfusão
Reação Transfusional.
Componentes de la sangre
Transfusión
Reacción de transfusión.
Blood components
Transfusion
Transfusion reaction.
description Transfusion therapy results in the transfusion of specific blood components, which the patient needs to replace, opposing the use of whole blood. This procedure aims to benefit several patients, and to optimize the stocks of blood banks. The presence of anti-erythrocyte antibodies in the serum of patients can cause hemolytic reactions. The identification of these antibodies is extremely necessary for the search for compatible blood components and, consequently, the prevention of transfusion reactions. The objective of this work is to describe the importance of pre-transfusion immunohematological techniques in the blood transfusion process. This is a qualitative bibliographic review based on scientific production based on studies already published. The decision to transfuse a patient must consider the risks and benefits and assess whether there is a real need for blood transfusion. The evaluation occurs through hemoglobin values ​​(for red blood cell transfusions) and platelet values ​​(for blood platelet transfusions) and the clinical aspects of the patient. The introduction of laboratory tests and better donor screening have significantly reduced mortality rates and risks of infections related to this procedure and the most frequent complications today are related to non-infectious causes. Patients who frequently perform blood transfusions may become sensitized, producing alloantibodies, due to the presence of anti-erythrocyte antigens present in the transfused blood bags. These patients have a greater risk of developing transfusion reactions, therefore, the importance of pre-transfusion immunohematological techniques whose main function is to track the presence of irregular antibodies in the recipients and find compatible bags for blood transfusion, decreasing the risk of transfusion reactions and increasing patient safety.
publishDate 2020
dc.date.none.fl_str_mv 2020-08-02
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/6625
10.33448/rsd-v9i8.6625
url https://rsdjournal.org/index.php/rsd/article/view/6625
identifier_str_mv 10.33448/rsd-v9i8.6625
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/6625/6033
dc.rights.driver.fl_str_mv Copyright (c) 2020 Lennara Pereira Mota
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Lennara Pereira Mota
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 8; e936986625
Research, Society and Development; Vol. 9 Núm. 8; e936986625
Research, Society and Development; v. 9 n. 8; e936986625
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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