Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/26707 |
Resumo: | Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation, in many cases there may also be associated respiratory muscle dysfunction and a deficit in the ability to generate contractile force, resulting in muscle weakness. The aim of this study was to evaluate the effectiveness of Inspiratory Muscle Training (IMT) on pulmonary radioaerosol deposition in patients with COPD and respiratory muscle weakness. This is a randomized, double-blind clinical trial that will submit patients with COPD of different stages according to the criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) and with respiratory muscle weakness (MIP < 60cmH2O) to IMT (IMT Group) and sub-therapeutic load training (Control Group). Patients in the IMT Group will start training at 60% of MIP and training intensity will be increased weekly by 50% under the new MIP values measured. The control group will perform the protocol with 10% of the initial MIP and this value will remain constant throughout the training. The pulmonary deposition of radioaerosol will be measured through scintigraphy by the pulmonary deposition index (PDI), obtained through the ratio between the number of counts in each region of interest (ROI) by the total number of counts in the respective lung. There is a scarcity in the literature on the behavior of the pulmonary distribution of radioaerosols in this population, so far, no studies have been found that establish a relationship between the IMT in patients with COPD and respiratory muscle weakness and the improvement of pulmonary radioaerosol deposition. This finding reaffirms the importance of developing the present study, which may contribute to a better perspective of patients with COPD. |
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Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial ¿El entrenamiento de los músculos inspiratorios aumenta el depósito de radioaerosol pulmonar en pacientes con EPOC y debilidad de los músculos respiratorios?: Protocolo de estudio para ensayo clínico aleatorizado O treino muscular inspiratório aumenta a deposição de radioaerossol pulmonar em pacientes com DPOC com fraqueza muscular respiratória?: Um protocolo de estudo para ensaio clínico randomizadoDPOCExercício respiratórioTerapia com aerossóisCintilografia.EPOCEjercicio de respiraciónAerosolterapiaGammagrafía.COPDBreathing exerciseAerosol therapyScintigraphy.Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation, in many cases there may also be associated respiratory muscle dysfunction and a deficit in the ability to generate contractile force, resulting in muscle weakness. The aim of this study was to evaluate the effectiveness of Inspiratory Muscle Training (IMT) on pulmonary radioaerosol deposition in patients with COPD and respiratory muscle weakness. This is a randomized, double-blind clinical trial that will submit patients with COPD of different stages according to the criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) and with respiratory muscle weakness (MIP < 60cmH2O) to IMT (IMT Group) and sub-therapeutic load training (Control Group). Patients in the IMT Group will start training at 60% of MIP and training intensity will be increased weekly by 50% under the new MIP values measured. The control group will perform the protocol with 10% of the initial MIP and this value will remain constant throughout the training. The pulmonary deposition of radioaerosol will be measured through scintigraphy by the pulmonary deposition index (PDI), obtained through the ratio between the number of counts in each region of interest (ROI) by the total number of counts in the respective lung. There is a scarcity in the literature on the behavior of the pulmonary distribution of radioaerosols in this population, so far, no studies have been found that establish a relationship between the IMT in patients with COPD and respiratory muscle weakness and the improvement of pulmonary radioaerosol deposition. This finding reaffirms the importance of developing the present study, which may contribute to a better perspective of patients with COPD.La enfermedad pulmonar obstructiva crónica (EPOC) se caracteriza por una limitación crónica al flujo aéreo, en muchos casos también puede asociarse una disfunción de los músculos respiratorios y un déficit en la capacidad de generar fuerza contráctil, lo que resulta en debilidad muscular. El objetivo de este estudio fue evaluar la efectividad del entrenamiento muscular inspiratorio (EMI) sobre el depósito de radioaerosol pulmonar en pacientes con EPOC y debilidad de los músculos respiratorios. Se trata de un ensayo clínico aleatorizado, doble ciego, que someterá a EMI a pacientes con EPOC en diferentes estadios según los criterios de la Global Initiative for Chronic Obstructive Lung Disease (GOLD) y con debilidad de los músculos respiratorios (PImax < 60cmH2O) (Grupo EMI) y entrenamiento con carga subterapéutica (Grupo Control). Los pacientes del Grupo EMI comenzarán a entrenar al 60 % de la PImax y la intensidad del entrenamiento se incrementará semanalmente en un 50 % por debajo de los nuevos valores de la PImax medidos.El grupo control realizará el protocolo con el 10% de la PImax inicial y este valor se mantendrá constante durante todo el entrenamiento. El depósito pulmonar de radioaerosol será medido mediante gammagrafía por el índice de depósito pulmonar (IDP), obtenido a través de la relación entre el número de conteos en cada región de interés (ROI) por el número total de conteos en el respectivo pulmón. Existe escasez en la literatura sobre el comportamiento de la distribución pulmonar de los radioaerosoles en esta población, hasta el momento no se han encontrado estudios que establezcan una relación entre EMI en pacientes con EPOC y debilidad de los músculos respiratorios y la mejoría de la pulmonar. depósito de radioaerosoles. Este hallazgo reafirma la importancia de desarrollar el presente estudio, que puede contribuir a una mejor perspectiva de los pacientes con EPOC.A doença pulmonar obstrutiva crônica (DPOC) caracteriza-se por limitação crônica do fluxo aéreo, em muitos casos podendo ocorrer também disfunção muscular respiratória associada e déficit na capacidade de gerar força contrátil, resultando em fraqueza dessa musculatura. O objetivo desse estudo foi avaliar a eficácia do Treinamento Muscular Inspiratório (TMI) sobre a deposição de radioaerossol pulmonar em pacientes com DPOC e fraqueza muscular respiratória. Trata-se de um ensaio clínico randomizado e duplo cego que submeterá pacientes com DPOC de diferentes estadiamentos segundo os critérios da Global Initiative for Chronic Obstructive Lung Disease (GOLD) e com fraqueza muscular respiratória (PImax < 60cmH2O) ao TMI (Grupo TMI) e ao treino com carga sub-terapêutica (Grupo Controle). Os pacientes do Grupo TMI iniciarão o treinamento com 60% da PImax e a intensidade do treino será aumentada semanalmente em 50% sob os novos valores de PImax mensurados. O grupo controle realizará o protocolo de com 10% da PImax inicial e esse valor se manterá constante ao longo do treinamento. A deposição pulmonar de radioaerossol será mensurada através da cintilografia pelo índice de deposição pulmonar (IDP), obtido através da razão entre a quantidade de contagens de cada região de interesse (ROI) pela quantidade total de contagens do respectivo pulmão. Há uma escassez na literatura sobre o comportamento da distribuição pulmonar de radioaerossóis nessa população, até o momento, não foram encontrados estudos que estabeleçam relação entre o TMI em pacientes com DPOC e fraqueza muscular respiratória e a melhora da deposição de radioaerossol pulmonar. Tal constatação reafirma a importância do desenvolvimento do presente estudo que poderá contribuir para uma melhor perspectiva dos pacientes com DPOC. Research, Society and Development2022-02-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2670710.33448/rsd-v11i3.26707Research, Society and Development; Vol. 11 No. 3; e33211326707Research, Society and Development; Vol. 11 Núm. 3; e33211326707Research, Society and Development; v. 11 n. 3; e332113267072525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26707/23303Copyright (c) 2022 Lays Rodrigues; Dulciane Paiva; Taciano Rocha; Daniella Cunha Brandão; Armèle Dornelas de Andradehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRodrigues, LaysPaiva, Dulciane Rocha, Taciano Brandão, Daniella Cunha Andrade, Armèle Dornelas de2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26707Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:40.822862Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial ¿El entrenamiento de los músculos inspiratorios aumenta el depósito de radioaerosol pulmonar en pacientes con EPOC y debilidad de los músculos respiratorios?: Protocolo de estudio para ensayo clínico aleatorizado O treino muscular inspiratório aumenta a deposição de radioaerossol pulmonar em pacientes com DPOC com fraqueza muscular respiratória?: Um protocolo de estudo para ensaio clínico randomizado |
title |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial |
spellingShingle |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial Rodrigues, Lays DPOC Exercício respiratório Terapia com aerossóis Cintilografia. EPOC Ejercicio de respiración Aerosolterapia Gammagrafía. COPD Breathing exercise Aerosol therapy Scintigraphy. |
title_short |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial |
title_full |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial |
title_fullStr |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial |
title_full_unstemmed |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial |
title_sort |
Does inspiratory muscle training increase pulmonary radioaerosol deposition in COPD patients with respiratory muscle weakness?: A study protocol for a randomized clinical trial |
author |
Rodrigues, Lays |
author_facet |
Rodrigues, Lays Paiva, Dulciane Rocha, Taciano Brandão, Daniella Cunha Andrade, Armèle Dornelas de |
author_role |
author |
author2 |
Paiva, Dulciane Rocha, Taciano Brandão, Daniella Cunha Andrade, Armèle Dornelas de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Rodrigues, Lays Paiva, Dulciane Rocha, Taciano Brandão, Daniella Cunha Andrade, Armèle Dornelas de |
dc.subject.por.fl_str_mv |
DPOC Exercício respiratório Terapia com aerossóis Cintilografia. EPOC Ejercicio de respiración Aerosolterapia Gammagrafía. COPD Breathing exercise Aerosol therapy Scintigraphy. |
topic |
DPOC Exercício respiratório Terapia com aerossóis Cintilografia. EPOC Ejercicio de respiración Aerosolterapia Gammagrafía. COPD Breathing exercise Aerosol therapy Scintigraphy. |
description |
Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation, in many cases there may also be associated respiratory muscle dysfunction and a deficit in the ability to generate contractile force, resulting in muscle weakness. The aim of this study was to evaluate the effectiveness of Inspiratory Muscle Training (IMT) on pulmonary radioaerosol deposition in patients with COPD and respiratory muscle weakness. This is a randomized, double-blind clinical trial that will submit patients with COPD of different stages according to the criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) and with respiratory muscle weakness (MIP < 60cmH2O) to IMT (IMT Group) and sub-therapeutic load training (Control Group). Patients in the IMT Group will start training at 60% of MIP and training intensity will be increased weekly by 50% under the new MIP values measured. The control group will perform the protocol with 10% of the initial MIP and this value will remain constant throughout the training. The pulmonary deposition of radioaerosol will be measured through scintigraphy by the pulmonary deposition index (PDI), obtained through the ratio between the number of counts in each region of interest (ROI) by the total number of counts in the respective lung. There is a scarcity in the literature on the behavior of the pulmonary distribution of radioaerosols in this population, so far, no studies have been found that establish a relationship between the IMT in patients with COPD and respiratory muscle weakness and the improvement of pulmonary radioaerosol deposition. This finding reaffirms the importance of developing the present study, which may contribute to a better perspective of patients with COPD. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-02-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26707 10.33448/rsd-v11i3.26707 |
url |
https://rsdjournal.org/index.php/rsd/article/view/26707 |
identifier_str_mv |
10.33448/rsd-v11i3.26707 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26707/23303 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 3; e33211326707 Research, Society and Development; Vol. 11 Núm. 3; e33211326707 Research, Society and Development; v. 11 n. 3; e33211326707 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052763363868672 |