Atypical fibrous osteodystrophy in a lactating mare

Detalhes bibliográficos
Autor(a) principal: Silva, Andrezza Caroline Aragão da
Data de Publicação: 2020
Outros Autores: Escodro, Pierre Barnabé, Guimarães, Diego Nunes, Diniz, Anaemilia das Neves, Nunes, Annelise Castanha Barreto Tenorio, Campos, Fabricio Juliano de Oliveira, Andrade, Rachel Livingstone Felizola Soares de, Graboschii, Amanda Caroline Gomes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/5735
Resumo: Secondary nutritional hyperparathyroidism is a condition caused by increased serum phosphorus levels compared to calcium, which leads to an growth in the production of the PTH, parathyroid hormone of the parathyroid glands, increasing the osteoclastic activity withdrawing calcium from the bones, forming fibrous tissue, known as osteodystrophy, usually in the facial bones. The goal of this paper was to report an atypical case of hyperparathyroidism and fibrous osteodystrophy in a 8-year-old lactating mare, whose face enlargement was focal and nodular, involving of the right nostril and incisor bones, causing breathing and feeding difficulties. In the radiological examination the image was suggestive of osteosarcoma, with Doppler showing superficial circulation to the nodular mass. Treatment with cisplatin and calcium supplementation was performed. The the patient died three days after a temporary tracheostomy and a biopsy procedure. At necropsy parathyroid’s lymphadenomegaly was confirmed by histopathology, and osteodystrophy in the maxillary region was observed. In this case, hyperparathyroidism did not presented itself as a typical form, and there is a need for further studies on possible atypical forms of the disease on tropical countries.
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spelling Atypical fibrous osteodystrophy in a lactating mareOsteodistrofía fibrosa atípica en una yegua lactanteOsteodistrofia fibrosa atípica em uma égua lactanteEquinoHiperparatiroidismoOsteosarcomaDiagnóstico diferencialLinfadenomegalia.EquineHyperparathyroidismOsteosarcomaDifferential diagnosisLymphadenomegaly.EquinoHiperparatireoidismoOsteossarcomaDiagnóstico diferencialLinfadenomegalia.Secondary nutritional hyperparathyroidism is a condition caused by increased serum phosphorus levels compared to calcium, which leads to an growth in the production of the PTH, parathyroid hormone of the parathyroid glands, increasing the osteoclastic activity withdrawing calcium from the bones, forming fibrous tissue, known as osteodystrophy, usually in the facial bones. The goal of this paper was to report an atypical case of hyperparathyroidism and fibrous osteodystrophy in a 8-year-old lactating mare, whose face enlargement was focal and nodular, involving of the right nostril and incisor bones, causing breathing and feeding difficulties. In the radiological examination the image was suggestive of osteosarcoma, with Doppler showing superficial circulation to the nodular mass. Treatment with cisplatin and calcium supplementation was performed. The the patient died three days after a temporary tracheostomy and a biopsy procedure. At necropsy parathyroid’s lymphadenomegaly was confirmed by histopathology, and osteodystrophy in the maxillary region was observed. In this case, hyperparathyroidism did not presented itself as a typical form, and there is a need for further studies on possible atypical forms of the disease on tropical countries.El hiperparatiroidismo secundario a la nutrición es una afección causada por los altos niveles de fósforo en suero en comparación con el calcio que conduce a un aumento en la producción de parathormonio, hormona paratiroidea en las glándulas paratiroides, de modo que aumenta la actividad osteoclástica, secuestrando el calcio de los huesos y formando tejido fibroso. caracterizado como osteodistrofia que ocurre comúnmente en los huesos faciales. Este artículo tiene como objetivo describir un caso atípico de hiperparatiroidismo y osteodistrofia fibrosa en una yegua lactante de 8 años cuya cara tenía un agrandamiento focal y nodular que involucraba la fosa nasal derecha y los huesos incisivos que causaban dificultades para respirar y alimentarse. Los exámenes radiológicos sugirieron osteosarcoma con Doppler que indica circulación superficial a la masa nodular. El tratamiento se realizó con suplementos de cisplatino y calcio. El paciente falleció tres días después de realizar la traqueotomía temporal y los procedimientos de biopsia. Los hallazgos de la necropsia indicaron linfadenomegalia paratiroidea, confirmada por histopatología además de osteoartritis en la región maxilar. En este caso, el hiperparatiroidismo no apareció de manera típica, con la necesidad de más estudios sobre la posible atipia de la enfermedad en los países tropicales.O hiperparatireoidismo secundário à nutrição é uma condição causada por altos níveis séricos de fósforo em comparação ao cálcio levando a um aumento na produção de PTH, hormônio paratireoidiano das glândulas paratireoides de maneira que a atividade osteoclástica aumente, sequestrando cálcio dos ossos e formando um tecido fibroso caracterizado como osteodistrofia que ocorre comumente nos ossos faciais. Este artigo tem como objetivo descrever um caso atípico de hiperparatireoidismo e osteodistrofia fibrosa em uma égua em lactação de 8 anos cuja face possuía um aumento focal e nodular envolvendo a narina direita e os ossos incisivos causando dificuldades respiratórias e alimentares. Os exames radiológicos foram sugestivos de osteossarcoma com o Doppler indicando circulação superficial a massa nodular. O tratamento foi efetuado com cisplatina e suplementação de cálcio. O paciente foi a óbito três dias após a realização dos procedimentos de traqueostomia temporária e biópsia.  Os achados de necropsia indicaram linfadenomegalia da paratireóide, confirmada pela histopatologia além de osteodistrofia na região maxilar. Neste caso o hiperparatireoidismo não se apresentou de maneira típica, havendo uma necessidade de estudos posteriores sobre possíveis atipias da doença em países tropicais.Research, Society and Development2020-07-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/573510.33448/rsd-v9i8.5735Research, Society and Development; Vol. 9 No. 8; e422985735Research, Society and Development; Vol. 9 Núm. 8; e422985735Research, Society and Development; v. 9 n. 8; e4229857352525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/5735/4999Copyright (c) 2020 Andrezza Caroline Aragão da Silva, Pierre Barnabé Escodro, Diego Nunes Guimarães, Anaemilia das Neves Diniz, Annelise Castanha Barreto Tenorio Nunes, Fabricio J.O Campos, Rachel Livingstone Felizola Soares de Andrade, Amanda Caroline Gomes Graboschiihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Andrezza Caroline Aragão daEscodro, Pierre BarnabéGuimarães, Diego NunesDiniz, Anaemilia das NevesNunes, Annelise Castanha Barreto TenorioCampos, Fabricio Juliano de OliveiraAndrade, Rachel Livingstone Felizola Soares deGraboschii, Amanda Caroline Gomes2020-08-20T18:00:17Zoai:ojs.pkp.sfu.ca:article/5735Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:29:09.588029Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Atypical fibrous osteodystrophy in a lactating mare
Osteodistrofía fibrosa atípica en una yegua lactante
Osteodistrofia fibrosa atípica em uma égua lactante
title Atypical fibrous osteodystrophy in a lactating mare
spellingShingle Atypical fibrous osteodystrophy in a lactating mare
Silva, Andrezza Caroline Aragão da
Equino
Hiperparatiroidismo
Osteosarcoma
Diagnóstico diferencial
Linfadenomegalia.
Equine
Hyperparathyroidism
Osteosarcoma
Differential diagnosis
Lymphadenomegaly.
Equino
Hiperparatireoidismo
Osteossarcoma
Diagnóstico diferencial
Linfadenomegalia.
title_short Atypical fibrous osteodystrophy in a lactating mare
title_full Atypical fibrous osteodystrophy in a lactating mare
title_fullStr Atypical fibrous osteodystrophy in a lactating mare
title_full_unstemmed Atypical fibrous osteodystrophy in a lactating mare
title_sort Atypical fibrous osteodystrophy in a lactating mare
author Silva, Andrezza Caroline Aragão da
author_facet Silva, Andrezza Caroline Aragão da
Escodro, Pierre Barnabé
Guimarães, Diego Nunes
Diniz, Anaemilia das Neves
Nunes, Annelise Castanha Barreto Tenorio
Campos, Fabricio Juliano de Oliveira
Andrade, Rachel Livingstone Felizola Soares de
Graboschii, Amanda Caroline Gomes
author_role author
author2 Escodro, Pierre Barnabé
Guimarães, Diego Nunes
Diniz, Anaemilia das Neves
Nunes, Annelise Castanha Barreto Tenorio
Campos, Fabricio Juliano de Oliveira
Andrade, Rachel Livingstone Felizola Soares de
Graboschii, Amanda Caroline Gomes
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Andrezza Caroline Aragão da
Escodro, Pierre Barnabé
Guimarães, Diego Nunes
Diniz, Anaemilia das Neves
Nunes, Annelise Castanha Barreto Tenorio
Campos, Fabricio Juliano de Oliveira
Andrade, Rachel Livingstone Felizola Soares de
Graboschii, Amanda Caroline Gomes
dc.subject.por.fl_str_mv Equino
Hiperparatiroidismo
Osteosarcoma
Diagnóstico diferencial
Linfadenomegalia.
Equine
Hyperparathyroidism
Osteosarcoma
Differential diagnosis
Lymphadenomegaly.
Equino
Hiperparatireoidismo
Osteossarcoma
Diagnóstico diferencial
Linfadenomegalia.
topic Equino
Hiperparatiroidismo
Osteosarcoma
Diagnóstico diferencial
Linfadenomegalia.
Equine
Hyperparathyroidism
Osteosarcoma
Differential diagnosis
Lymphadenomegaly.
Equino
Hiperparatireoidismo
Osteossarcoma
Diagnóstico diferencial
Linfadenomegalia.
description Secondary nutritional hyperparathyroidism is a condition caused by increased serum phosphorus levels compared to calcium, which leads to an growth in the production of the PTH, parathyroid hormone of the parathyroid glands, increasing the osteoclastic activity withdrawing calcium from the bones, forming fibrous tissue, known as osteodystrophy, usually in the facial bones. The goal of this paper was to report an atypical case of hyperparathyroidism and fibrous osteodystrophy in a 8-year-old lactating mare, whose face enlargement was focal and nodular, involving of the right nostril and incisor bones, causing breathing and feeding difficulties. In the radiological examination the image was suggestive of osteosarcoma, with Doppler showing superficial circulation to the nodular mass. Treatment with cisplatin and calcium supplementation was performed. The the patient died three days after a temporary tracheostomy and a biopsy procedure. At necropsy parathyroid’s lymphadenomegaly was confirmed by histopathology, and osteodystrophy in the maxillary region was observed. In this case, hyperparathyroidism did not presented itself as a typical form, and there is a need for further studies on possible atypical forms of the disease on tropical countries.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-11
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/5735
10.33448/rsd-v9i8.5735
url https://rsdjournal.org/index.php/rsd/article/view/5735
identifier_str_mv 10.33448/rsd-v9i8.5735
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/5735/4999
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 8; e422985735
Research, Society and Development; Vol. 9 Núm. 8; e422985735
Research, Society and Development; v. 9 n. 8; e422985735
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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