New alkaloids from Ocotea duckei vattimo (Lauraceae)
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/12800 |
Resumo: | Ocotea duckei Vattimo, popularly known as “louro-de-cheiro”, “louro-pimenta”, and “louro-canela” is a member of the Lauraceae family found in the Northeast region of Brazil. It is popularly used to treat neuralgia, dyspepsia, anorexia and pain. This current study aimed to promote the isolation and the identification / determination of new secondary metabolites of the species O. duckei Vattimo. In order to obtain the vegetable drug of O. duckei, its stem barks were harvested and submitted to a drying process followed by pulverization. The Crude Ethanolic Extract (BSE), obtained from the vegetable drug, was then subjected to an alkaloid extraction protocol in order to generate its Total Alkaloid Fraction (TAF). The isolation and identification of chemical compounds were carried out by chromatographic and spectroscopic methods respectively. The chemical investigation of O. duckei resulted in the isolation of three compounds: Ocoteaduccin A (OD-1, 0.020 g), Ocoteaduccin B (OD-2, 0.015 g), and N-methylcoclaurine (OD-3, 0.008 g). O. duckei proved to be a promising species, due to the variety of isolated chemical compounds. Further chemical, pharmacological and toxicological studies must be conducted in order to improve the phytochemical knowledge about this plant. |
id |
UNIFEI_2a02d827078ba5d1b40b578546a7ebb0 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/12800 |
network_acronym_str |
UNIFEI |
network_name_str |
Research, Society and Development |
repository_id_str |
|
spelling |
New alkaloids from Ocotea duckei vattimo (Lauraceae) Nuevos alcaloides de Ocotea duckei vattimo (Lauraceae) Novos alcaloides de Ocotea duckei vattimo (Lauraceae) OcoteaLauraceaeAlcaloidesCompuestos químicos.OcoteaLauraceaeAlcaloidesCompostos químicos.OcoteaLauraceaeAlkaloidsChemical compounds.Ocotea duckei Vattimo, popularly known as “louro-de-cheiro”, “louro-pimenta”, and “louro-canela” is a member of the Lauraceae family found in the Northeast region of Brazil. It is popularly used to treat neuralgia, dyspepsia, anorexia and pain. This current study aimed to promote the isolation and the identification / determination of new secondary metabolites of the species O. duckei Vattimo. In order to obtain the vegetable drug of O. duckei, its stem barks were harvested and submitted to a drying process followed by pulverization. The Crude Ethanolic Extract (BSE), obtained from the vegetable drug, was then subjected to an alkaloid extraction protocol in order to generate its Total Alkaloid Fraction (TAF). The isolation and identification of chemical compounds were carried out by chromatographic and spectroscopic methods respectively. The chemical investigation of O. duckei resulted in the isolation of three compounds: Ocoteaduccin A (OD-1, 0.020 g), Ocoteaduccin B (OD-2, 0.015 g), and N-methylcoclaurine (OD-3, 0.008 g). O. duckei proved to be a promising species, due to the variety of isolated chemical compounds. Further chemical, pharmacological and toxicological studies must be conducted in order to improve the phytochemical knowledge about this plant.Ocotea duckei Vattimo, conocida popularmente como "laurel-olfato", "laurel-pimienta" y "laurel-canela" es un miembro de la familia Lauraceae que se encuentra en el noreste de Brasil. Se utiliza popularmente para tratar la neuralgia, la dispepsia, la anorexia y el dolor. El presente estudio tuvo como objetivo promover el aislamiento y la identificación / determinación de nuevos metabolitos secundarios de la especie O. duckei Vattimo. La corteza del tallo después de la recolección, pasó por el proceso de secado y fue triturada para obtener la droga vegetal. El Extracto Etanólico Crudo (EEB) se obtuvo a partir de la droga vegetal, de la EEB se realizó una marcha a Alcaloides, obteniendo así la Fracción de Alcaloides Totales (FAT). El aislamiento y la identificación de compuestos químicos se llevaron a cabo mediante métodos cromatográficos y espectroscópicos respectivamente. El estudio fitoquímico de O. duckei dio como resultado el aislamiento de tres sustancias: ocoteaduccina A (OD-1, 0,020 g), ocoteaduccina B (OD-2, 0,015 g), N-metilcoclaurina (OD-3, 0,008 g). O. duckei resultó ser una especie prometedora, debido a la variedad de compuestos químicos aislados. Se deben realizar más estudios químicos, farmacológicos y toxicológicos para promover el conocimiento sobre esta planta.Ocotea duckei Vattimo, popularmente conhecido como “louro-de-cheiro”, “louro-pimenta” e “louro-canela” é um membro da família Lauraceae encontrada no Nordeste do Brasil. Popularmente é utilizado no tratamento de neuralgia, dispepsia, anorexia e dor. O presente estudo teve por objetivo promover o isolamento e a identificação/determinação de novos metabólitos secundários da espécie O. duckei Vattimo. A fim de obter a droga vegetal de O. duckei, as cascas do caule foram coletadas e submetidas ao processo de secagem. O Extrato Etanólico Bruto (EEB), obtido a partir da droga vegetal foi então direcionado a uma marcha para Alcaloides, resultando na Fração de Alcaloides Totais (FAT) correspondente. O isolamento e a identificação dos compostos químicos foram realizados por métodos cromatográficos e espectroscópicos respectivamente. O estudo fitoquímico de O. duckei resultou no isolamento de três substâncias: Ocoteaduccina A (OD-1, 0,020 g), Ocoteaduccina B (OD-2, 0,015 g) e N-metilcoclaurina (OD-3, 0,008 g). A O. duckei demonstrou ser uma espécie promissora, pela variedade de compostos químicos isolados. Mais estudos químicos, farmacológicos e toxicológicos devem ser feitos a fim de melhorar o conhecimento fitoquímico acerca desta planta. Research, Society and Development2021-04-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1280010.33448/rsd-v10i4.12800Research, Society and Development; Vol. 10 No. 4; e28910412800Research, Society and Development; Vol. 10 Núm. 4; e28910412800Research, Society and Development; v. 10 n. 4; e289104128002525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/12800/12691Copyright (c) 2021 Laisla Rangel Peixoto; Josean Fechine Tavares; Yuri Mangueira do Nascimento; Augusto Lopes Souto; Raimundo Braz Filho; Fabio Santos de Souza; José Maria Barbosa Filhohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPeixoto, Laisla Rangel Tavares, Josean Fechine Nascimento, Yuri Mangueira do Souto, Augusto Lopes Braz Filho, RaimundoSouza, Fabio Santos de Barbosa Filho, José Maria2021-04-25T11:21:26Zoai:ojs.pkp.sfu.ca:article/12800Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:34:17.329177Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
New alkaloids from Ocotea duckei vattimo (Lauraceae) Nuevos alcaloides de Ocotea duckei vattimo (Lauraceae) Novos alcaloides de Ocotea duckei vattimo (Lauraceae) |
title |
New alkaloids from Ocotea duckei vattimo (Lauraceae) |
spellingShingle |
New alkaloids from Ocotea duckei vattimo (Lauraceae) Peixoto, Laisla Rangel Ocotea Lauraceae Alcaloides Compuestos químicos. Ocotea Lauraceae Alcaloides Compostos químicos. Ocotea Lauraceae Alkaloids Chemical compounds. |
title_short |
New alkaloids from Ocotea duckei vattimo (Lauraceae) |
title_full |
New alkaloids from Ocotea duckei vattimo (Lauraceae) |
title_fullStr |
New alkaloids from Ocotea duckei vattimo (Lauraceae) |
title_full_unstemmed |
New alkaloids from Ocotea duckei vattimo (Lauraceae) |
title_sort |
New alkaloids from Ocotea duckei vattimo (Lauraceae) |
author |
Peixoto, Laisla Rangel |
author_facet |
Peixoto, Laisla Rangel Tavares, Josean Fechine Nascimento, Yuri Mangueira do Souto, Augusto Lopes Braz Filho, Raimundo Souza, Fabio Santos de Barbosa Filho, José Maria |
author_role |
author |
author2 |
Tavares, Josean Fechine Nascimento, Yuri Mangueira do Souto, Augusto Lopes Braz Filho, Raimundo Souza, Fabio Santos de Barbosa Filho, José Maria |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Peixoto, Laisla Rangel Tavares, Josean Fechine Nascimento, Yuri Mangueira do Souto, Augusto Lopes Braz Filho, Raimundo Souza, Fabio Santos de Barbosa Filho, José Maria |
dc.subject.por.fl_str_mv |
Ocotea Lauraceae Alcaloides Compuestos químicos. Ocotea Lauraceae Alcaloides Compostos químicos. Ocotea Lauraceae Alkaloids Chemical compounds. |
topic |
Ocotea Lauraceae Alcaloides Compuestos químicos. Ocotea Lauraceae Alcaloides Compostos químicos. Ocotea Lauraceae Alkaloids Chemical compounds. |
description |
Ocotea duckei Vattimo, popularly known as “louro-de-cheiro”, “louro-pimenta”, and “louro-canela” is a member of the Lauraceae family found in the Northeast region of Brazil. It is popularly used to treat neuralgia, dyspepsia, anorexia and pain. This current study aimed to promote the isolation and the identification / determination of new secondary metabolites of the species O. duckei Vattimo. In order to obtain the vegetable drug of O. duckei, its stem barks were harvested and submitted to a drying process followed by pulverization. The Crude Ethanolic Extract (BSE), obtained from the vegetable drug, was then subjected to an alkaloid extraction protocol in order to generate its Total Alkaloid Fraction (TAF). The isolation and identification of chemical compounds were carried out by chromatographic and spectroscopic methods respectively. The chemical investigation of O. duckei resulted in the isolation of three compounds: Ocoteaduccin A (OD-1, 0.020 g), Ocoteaduccin B (OD-2, 0.015 g), and N-methylcoclaurine (OD-3, 0.008 g). O. duckei proved to be a promising species, due to the variety of isolated chemical compounds. Further chemical, pharmacological and toxicological studies must be conducted in order to improve the phytochemical knowledge about this plant. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-04-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/12800 10.33448/rsd-v10i4.12800 |
url |
https://rsdjournal.org/index.php/rsd/article/view/12800 |
identifier_str_mv |
10.33448/rsd-v10i4.12800 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/12800/12691 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 4; e28910412800 Research, Society and Development; Vol. 10 Núm. 4; e28910412800 Research, Society and Development; v. 10 n. 4; e28910412800 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052670976983040 |