Pharmacological treatment for endometriosis

Detalhes bibliográficos
Autor(a) principal: Santos, Camila Maria do Nascimento
Data de Publicação: 2021
Outros Autores: Monte , Luiz Eduardo Macêdo do, Pinheiro Neto, José Chagas, Silva, Higo José Neri da, Melo, Antonia Filha Moreira de, Borges, Sérgio Henrique Assunção Lacerda, Sousa, Alisson Camilo Martins, Oliveira, Juciara Carvalho de, Santana, Fabiana de Souza, Marinho, Anna Letícia de Sousa, Gualberto , Márcia Araújo, Sousa , Ian Jhemes Oliveira, Gonçalves, Rodrigo Lopes Gomes, Silva, Kelly Maria Rêgo da, Pinheiro, Iluska Martins
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/16104
Resumo:   Endometriosis is a gynecological disease characterized by the presence of endometrium as tissue-epithelium and stroma that develops outside the uterine cavity. It is a chronic, estrogen-dependent disease, is associated with pelvic pain, dysmenorrhea, dyspareunia and infertility. Given the great impact of this disease on the quality of life of women, there has been a growing interest in the discovery of new drugs that are more effective, tolerability and safety. For this, a literature review was carried out from articles published between 2008 and 2018 available regarding pharmacological treatments for endometriosis in the SCIENCE DIRECT and PUBMED databases. A total of 223 articles published in the last 10 years were found in "Portuguese and English". After evaluating the articles, 15 articles were selected for the present study, which complied with all the eligibility criteria proposed in the methodology. It was concluded that we can count on several types of treatments for endometriosis, but most have the objective of treating the symptoms associated with endometriosis. Currently, the specific treatment we can count on is dienogeste. In addition, there are many studies in search of new drugs and promising treatments for this pathology. Thus, more research is needed regarding the theme and that the pharmacist plays a fundamental role in the adherence to the patient's treatment.
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spelling Pharmacological treatment for endometriosisTratamiento farmacológico para la endometriosisTratamento farmacológico para endometriose Tratamento FarmacológicoEndometrioseTerapia combinada.Pharmacological TreatmentEndometriosisCombined therapy.Tratamiento farmacológicoEndometriosisTerapia combinada.  Endometriosis is a gynecological disease characterized by the presence of endometrium as tissue-epithelium and stroma that develops outside the uterine cavity. It is a chronic, estrogen-dependent disease, is associated with pelvic pain, dysmenorrhea, dyspareunia and infertility. Given the great impact of this disease on the quality of life of women, there has been a growing interest in the discovery of new drugs that are more effective, tolerability and safety. For this, a literature review was carried out from articles published between 2008 and 2018 available regarding pharmacological treatments for endometriosis in the SCIENCE DIRECT and PUBMED databases. A total of 223 articles published in the last 10 years were found in "Portuguese and English". After evaluating the articles, 15 articles were selected for the present study, which complied with all the eligibility criteria proposed in the methodology. It was concluded that we can count on several types of treatments for endometriosis, but most have the objective of treating the symptoms associated with endometriosis. Currently, the specific treatment we can count on is dienogeste. In addition, there are many studies in search of new drugs and promising treatments for this pathology. Thus, more research is needed regarding the theme and that the pharmacist plays a fundamental role in the adherence to the patient's treatment.La endometriosis es una enfermedad ginecológica que se caracteriza por la presencia de endometrio como tejido-epitelio y estroma que se desarrolla fuera de la cavidad uterina. Es una enfermedad crónica dependiente de estrógenos, asociada a dolor pélvico, dismenorrea, dispareunia e infertilidad. Dado el gran impacto de esta enfermedad en la calidad de vida de las mujeres, ha habido un interés creciente en el descubrimiento de fármacos nuevos, más eficaces, de tolerabilidad y seguridad. Para ello, se realizó una revisión de la literatura a partir de los artículos publicados entre los años 2008 a 2018 disponibles sobre los tratamientos farmacológicos para la endometriosis, en las bases de datos SCIENCE DIRECT y PUBMED. Se encontraron un total de 223 artículos publicados en los últimos 10 años en “portugués e inglés”. Luego de evaluar los artículos, se seleccionaron 15 artículos para el presente estudio, los cuales cumplieron con todos los criterios de elegibilidad propuestos en la metodología. Se concluyó que podemos contar con varios tipos de tratamientos para la endometriosis, pero que la mayoría de ellos tienen como objetivo tratar los síntomas asociados a la endometriosis. Actualmente el tratamiento específico con el que podemos contar es el Dienogeste. Además, son muchos los estudios que buscan nuevos fármacos y tratamientos prometedores para esta patología. Por tanto, se necesita más investigación sobre el tema y que el farmacéutico tiene un papel fundamental en la adherencia al tratamiento del paciente.A endometriose é uma doença ginecológica que se caracteriza pela presença de endométrio como tecido-epitélio e estroma que se desenvolve fora da cavidade uterina. É uma doença crónica, estrogênio-dependente, é associada com dor pélvica, dismenorreia, dispareunia e infertilidade. Dado o grande impacto desta doença na qualidade de vida das mulheres, tem-se verificado um interesse crescente na descoberta de novos fármacos mais eficazes, tolerabilidade e segurança. Para isso, realizou-se uma revisão da literatura a partir de artigos publicados entre os anos de 2008 a 2018 disponíveis a respeito dos Tratamentos farmacológicos para endometriose, nas bases de dados SCIENCE DIRECT e PUBMED. Encontrou-se um total de 223 artigos publicados nos últimos 10 anos, em “português e inglês”. Após avaliação dos artigos, foram selecionados 15 artigos para o presente estudo, que cumpriram com todos os critérios de elegibilidade proposto na metodologia. Concluiu-se que podemos contar com vários tipos de tratamentos para endometriose, mas que a maioria tem como objetivo tratar os sintomas associados à endometriose. Atualmente o tratamento específico que podemos contar é o Dienogeste. Além disso, existem muitos estudos em busca de novas drogas e tratamentos promissores para essa patologia. Assim, fazem-se necessárias mais pesquisas a respeito do tema e que o farmacêutico tem papel fundamental para a adesão ao tratamento do paciente.Research, Society and Development2021-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1610410.33448/rsd-v10i7.16104Research, Society and Development; Vol. 10 No. 7; e52810716104Research, Society and Development; Vol. 10 Núm. 7; e52810716104Research, Society and Development; v. 10 n. 7; e528107161042525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/16104/15091Copyright (c) 2021 Camila Maria do Nascimento Santos; Luiz Eduardo Macêdo do Monte ; José Chagas Pinheiro Neto; Higo José Neri da Silva; Antonia Filha Moreira de Melo; Sérgio Henrique Assunção Lacerda Borges; Alisson Camilo Martins Sousa; Juciara Carvalho de Oliveira; Fabiana de Souza Santana; Anna Letícia de Sousa Marinho; Márcia Araújo Gualberto ; Ian Jhemes Oliveira Sousa ; Rodrigo Lopes Gomes Gonçalves; Kelly Maria Rêgo da Silva; Iluska Martins Pinheirohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Camila Maria do Nascimento Monte , Luiz Eduardo Macêdo do Pinheiro Neto, José ChagasSilva, Higo José Neri da Melo, Antonia Filha Moreira de Borges, Sérgio Henrique Assunção LacerdaSousa, Alisson Camilo MartinsOliveira, Juciara Carvalho de Santana, Fabiana de SouzaMarinho, Anna Letícia de SousaGualberto , Márcia Araújo Sousa , Ian Jhemes OliveiraGonçalves, Rodrigo Lopes Gomes Silva, Kelly Maria Rêgo da Pinheiro, Iluska Martins2021-07-18T21:07:03Zoai:ojs.pkp.sfu.ca:article/16104Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:45.282444Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Pharmacological treatment for endometriosis
Tratamiento farmacológico para la endometriosis
Tratamento farmacológico para endometriose
title Pharmacological treatment for endometriosis
spellingShingle Pharmacological treatment for endometriosis
Santos, Camila Maria do Nascimento
Tratamento Farmacológico
Endometriose
Terapia combinada.
Pharmacological Treatment
Endometriosis
Combined therapy.
Tratamiento farmacológico
Endometriosis
Terapia combinada.
title_short Pharmacological treatment for endometriosis
title_full Pharmacological treatment for endometriosis
title_fullStr Pharmacological treatment for endometriosis
title_full_unstemmed Pharmacological treatment for endometriosis
title_sort Pharmacological treatment for endometriosis
author Santos, Camila Maria do Nascimento
author_facet Santos, Camila Maria do Nascimento
Monte , Luiz Eduardo Macêdo do
Pinheiro Neto, José Chagas
Silva, Higo José Neri da
Melo, Antonia Filha Moreira de
Borges, Sérgio Henrique Assunção Lacerda
Sousa, Alisson Camilo Martins
Oliveira, Juciara Carvalho de
Santana, Fabiana de Souza
Marinho, Anna Letícia de Sousa
Gualberto , Márcia Araújo
Sousa , Ian Jhemes Oliveira
Gonçalves, Rodrigo Lopes Gomes
Silva, Kelly Maria Rêgo da
Pinheiro, Iluska Martins
author_role author
author2 Monte , Luiz Eduardo Macêdo do
Pinheiro Neto, José Chagas
Silva, Higo José Neri da
Melo, Antonia Filha Moreira de
Borges, Sérgio Henrique Assunção Lacerda
Sousa, Alisson Camilo Martins
Oliveira, Juciara Carvalho de
Santana, Fabiana de Souza
Marinho, Anna Letícia de Sousa
Gualberto , Márcia Araújo
Sousa , Ian Jhemes Oliveira
Gonçalves, Rodrigo Lopes Gomes
Silva, Kelly Maria Rêgo da
Pinheiro, Iluska Martins
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Santos, Camila Maria do Nascimento
Monte , Luiz Eduardo Macêdo do
Pinheiro Neto, José Chagas
Silva, Higo José Neri da
Melo, Antonia Filha Moreira de
Borges, Sérgio Henrique Assunção Lacerda
Sousa, Alisson Camilo Martins
Oliveira, Juciara Carvalho de
Santana, Fabiana de Souza
Marinho, Anna Letícia de Sousa
Gualberto , Márcia Araújo
Sousa , Ian Jhemes Oliveira
Gonçalves, Rodrigo Lopes Gomes
Silva, Kelly Maria Rêgo da
Pinheiro, Iluska Martins
dc.subject.por.fl_str_mv Tratamento Farmacológico
Endometriose
Terapia combinada.
Pharmacological Treatment
Endometriosis
Combined therapy.
Tratamiento farmacológico
Endometriosis
Terapia combinada.
topic Tratamento Farmacológico
Endometriose
Terapia combinada.
Pharmacological Treatment
Endometriosis
Combined therapy.
Tratamiento farmacológico
Endometriosis
Terapia combinada.
description   Endometriosis is a gynecological disease characterized by the presence of endometrium as tissue-epithelium and stroma that develops outside the uterine cavity. It is a chronic, estrogen-dependent disease, is associated with pelvic pain, dysmenorrhea, dyspareunia and infertility. Given the great impact of this disease on the quality of life of women, there has been a growing interest in the discovery of new drugs that are more effective, tolerability and safety. For this, a literature review was carried out from articles published between 2008 and 2018 available regarding pharmacological treatments for endometriosis in the SCIENCE DIRECT and PUBMED databases. A total of 223 articles published in the last 10 years were found in "Portuguese and English". After evaluating the articles, 15 articles were selected for the present study, which complied with all the eligibility criteria proposed in the methodology. It was concluded that we can count on several types of treatments for endometriosis, but most have the objective of treating the symptoms associated with endometriosis. Currently, the specific treatment we can count on is dienogeste. In addition, there are many studies in search of new drugs and promising treatments for this pathology. Thus, more research is needed regarding the theme and that the pharmacist plays a fundamental role in the adherence to the patient's treatment.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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format article
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dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/16104
10.33448/rsd-v10i7.16104
url https://rsdjournal.org/index.php/rsd/article/view/16104
identifier_str_mv 10.33448/rsd-v10i7.16104
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/16104/15091
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 7; e52810716104
Research, Society and Development; Vol. 10 Núm. 7; e52810716104
Research, Society and Development; v. 10 n. 7; e52810716104
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
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reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
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