Pharmacological treatment for endometriosis
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
DOI: | 10.33448/rsd-v10i7.16104 |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/16104 |
Resumo: | Endometriosis is a gynecological disease characterized by the presence of endometrium as tissue-epithelium and stroma that develops outside the uterine cavity. It is a chronic, estrogen-dependent disease, is associated with pelvic pain, dysmenorrhea, dyspareunia and infertility. Given the great impact of this disease on the quality of life of women, there has been a growing interest in the discovery of new drugs that are more effective, tolerability and safety. For this, a literature review was carried out from articles published between 2008 and 2018 available regarding pharmacological treatments for endometriosis in the SCIENCE DIRECT and PUBMED databases. A total of 223 articles published in the last 10 years were found in "Portuguese and English". After evaluating the articles, 15 articles were selected for the present study, which complied with all the eligibility criteria proposed in the methodology. It was concluded that we can count on several types of treatments for endometriosis, but most have the objective of treating the symptoms associated with endometriosis. Currently, the specific treatment we can count on is dienogeste. In addition, there are many studies in search of new drugs and promising treatments for this pathology. Thus, more research is needed regarding the theme and that the pharmacist plays a fundamental role in the adherence to the patient's treatment. |
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Pharmacological treatment for endometriosisTratamiento farmacológico para la endometriosisTratamento farmacológico para endometriose Tratamento FarmacológicoEndometrioseTerapia combinada.Pharmacological TreatmentEndometriosisCombined therapy.Tratamiento farmacológicoEndometriosisTerapia combinada. Endometriosis is a gynecological disease characterized by the presence of endometrium as tissue-epithelium and stroma that develops outside the uterine cavity. It is a chronic, estrogen-dependent disease, is associated with pelvic pain, dysmenorrhea, dyspareunia and infertility. Given the great impact of this disease on the quality of life of women, there has been a growing interest in the discovery of new drugs that are more effective, tolerability and safety. For this, a literature review was carried out from articles published between 2008 and 2018 available regarding pharmacological treatments for endometriosis in the SCIENCE DIRECT and PUBMED databases. A total of 223 articles published in the last 10 years were found in "Portuguese and English". After evaluating the articles, 15 articles were selected for the present study, which complied with all the eligibility criteria proposed in the methodology. It was concluded that we can count on several types of treatments for endometriosis, but most have the objective of treating the symptoms associated with endometriosis. Currently, the specific treatment we can count on is dienogeste. In addition, there are many studies in search of new drugs and promising treatments for this pathology. Thus, more research is needed regarding the theme and that the pharmacist plays a fundamental role in the adherence to the patient's treatment.La endometriosis es una enfermedad ginecológica que se caracteriza por la presencia de endometrio como tejido-epitelio y estroma que se desarrolla fuera de la cavidad uterina. Es una enfermedad crónica dependiente de estrógenos, asociada a dolor pélvico, dismenorrea, dispareunia e infertilidad. Dado el gran impacto de esta enfermedad en la calidad de vida de las mujeres, ha habido un interés creciente en el descubrimiento de fármacos nuevos, más eficaces, de tolerabilidad y seguridad. Para ello, se realizó una revisión de la literatura a partir de los artículos publicados entre los años 2008 a 2018 disponibles sobre los tratamientos farmacológicos para la endometriosis, en las bases de datos SCIENCE DIRECT y PUBMED. Se encontraron un total de 223 artículos publicados en los últimos 10 años en “portugués e inglés”. Luego de evaluar los artículos, se seleccionaron 15 artículos para el presente estudio, los cuales cumplieron con todos los criterios de elegibilidad propuestos en la metodología. Se concluyó que podemos contar con varios tipos de tratamientos para la endometriosis, pero que la mayoría de ellos tienen como objetivo tratar los síntomas asociados a la endometriosis. Actualmente el tratamiento específico con el que podemos contar es el Dienogeste. Además, son muchos los estudios que buscan nuevos fármacos y tratamientos prometedores para esta patología. Por tanto, se necesita más investigación sobre el tema y que el farmacéutico tiene un papel fundamental en la adherencia al tratamiento del paciente.A endometriose é uma doença ginecológica que se caracteriza pela presença de endométrio como tecido-epitélio e estroma que se desenvolve fora da cavidade uterina. É uma doença crónica, estrogênio-dependente, é associada com dor pélvica, dismenorreia, dispareunia e infertilidade. Dado o grande impacto desta doença na qualidade de vida das mulheres, tem-se verificado um interesse crescente na descoberta de novos fármacos mais eficazes, tolerabilidade e segurança. Para isso, realizou-se uma revisão da literatura a partir de artigos publicados entre os anos de 2008 a 2018 disponíveis a respeito dos Tratamentos farmacológicos para endometriose, nas bases de dados SCIENCE DIRECT e PUBMED. Encontrou-se um total de 223 artigos publicados nos últimos 10 anos, em “português e inglês”. Após avaliação dos artigos, foram selecionados 15 artigos para o presente estudo, que cumpriram com todos os critérios de elegibilidade proposto na metodologia. Concluiu-se que podemos contar com vários tipos de tratamentos para endometriose, mas que a maioria tem como objetivo tratar os sintomas associados à endometriose. Atualmente o tratamento específico que podemos contar é o Dienogeste. Além disso, existem muitos estudos em busca de novas drogas e tratamentos promissores para essa patologia. Assim, fazem-se necessárias mais pesquisas a respeito do tema e que o farmacêutico tem papel fundamental para a adesão ao tratamento do paciente.Research, Society and Development2021-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1610410.33448/rsd-v10i7.16104Research, Society and Development; Vol. 10 No. 7; e52810716104Research, Society and Development; Vol. 10 Núm. 7; e52810716104Research, Society and Development; v. 10 n. 7; e528107161042525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/16104/15091Copyright (c) 2021 Camila Maria do Nascimento Santos; Luiz Eduardo Macêdo do Monte ; José Chagas Pinheiro Neto; Higo José Neri da Silva; Antonia Filha Moreira de Melo; Sérgio Henrique Assunção Lacerda Borges; Alisson Camilo Martins Sousa; Juciara Carvalho de Oliveira; Fabiana de Souza Santana; Anna Letícia de Sousa Marinho; Márcia Araújo Gualberto ; Ian Jhemes Oliveira Sousa ; Rodrigo Lopes Gomes Gonçalves; Kelly Maria Rêgo da Silva; Iluska Martins Pinheirohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Camila Maria do Nascimento Monte , Luiz Eduardo Macêdo do Pinheiro Neto, José ChagasSilva, Higo José Neri da Melo, Antonia Filha Moreira de Borges, Sérgio Henrique Assunção LacerdaSousa, Alisson Camilo MartinsOliveira, Juciara Carvalho de Santana, Fabiana de SouzaMarinho, Anna Letícia de SousaGualberto , Márcia Araújo Sousa , Ian Jhemes OliveiraGonçalves, Rodrigo Lopes Gomes Silva, Kelly Maria Rêgo da Pinheiro, Iluska Martins2021-07-18T21:07:03Zoai:ojs.pkp.sfu.ca:article/16104Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:45.282444Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Pharmacological treatment for endometriosis Tratamiento farmacológico para la endometriosis Tratamento farmacológico para endometriose |
title |
Pharmacological treatment for endometriosis |
spellingShingle |
Pharmacological treatment for endometriosis Pharmacological treatment for endometriosis Santos, Camila Maria do Nascimento Tratamento Farmacológico Endometriose Terapia combinada. Pharmacological Treatment Endometriosis Combined therapy. Tratamiento farmacológico Endometriosis Terapia combinada. Santos, Camila Maria do Nascimento Tratamento Farmacológico Endometriose Terapia combinada. Pharmacological Treatment Endometriosis Combined therapy. Tratamiento farmacológico Endometriosis Terapia combinada. |
title_short |
Pharmacological treatment for endometriosis |
title_full |
Pharmacological treatment for endometriosis |
title_fullStr |
Pharmacological treatment for endometriosis Pharmacological treatment for endometriosis |
title_full_unstemmed |
Pharmacological treatment for endometriosis Pharmacological treatment for endometriosis |
title_sort |
Pharmacological treatment for endometriosis |
author |
Santos, Camila Maria do Nascimento |
author_facet |
Santos, Camila Maria do Nascimento Santos, Camila Maria do Nascimento Monte , Luiz Eduardo Macêdo do Pinheiro Neto, José Chagas Silva, Higo José Neri da Melo, Antonia Filha Moreira de Borges, Sérgio Henrique Assunção Lacerda Sousa, Alisson Camilo Martins Oliveira, Juciara Carvalho de Santana, Fabiana de Souza Marinho, Anna Letícia de Sousa Gualberto , Márcia Araújo Sousa , Ian Jhemes Oliveira Gonçalves, Rodrigo Lopes Gomes Silva, Kelly Maria Rêgo da Pinheiro, Iluska Martins Monte , Luiz Eduardo Macêdo do Pinheiro Neto, José Chagas Silva, Higo José Neri da Melo, Antonia Filha Moreira de Borges, Sérgio Henrique Assunção Lacerda Sousa, Alisson Camilo Martins Oliveira, Juciara Carvalho de Santana, Fabiana de Souza Marinho, Anna Letícia de Sousa Gualberto , Márcia Araújo Sousa , Ian Jhemes Oliveira Gonçalves, Rodrigo Lopes Gomes Silva, Kelly Maria Rêgo da Pinheiro, Iluska Martins |
author_role |
author |
author2 |
Monte , Luiz Eduardo Macêdo do Pinheiro Neto, José Chagas Silva, Higo José Neri da Melo, Antonia Filha Moreira de Borges, Sérgio Henrique Assunção Lacerda Sousa, Alisson Camilo Martins Oliveira, Juciara Carvalho de Santana, Fabiana de Souza Marinho, Anna Letícia de Sousa Gualberto , Márcia Araújo Sousa , Ian Jhemes Oliveira Gonçalves, Rodrigo Lopes Gomes Silva, Kelly Maria Rêgo da Pinheiro, Iluska Martins |
author2_role |
author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Camila Maria do Nascimento Monte , Luiz Eduardo Macêdo do Pinheiro Neto, José Chagas Silva, Higo José Neri da Melo, Antonia Filha Moreira de Borges, Sérgio Henrique Assunção Lacerda Sousa, Alisson Camilo Martins Oliveira, Juciara Carvalho de Santana, Fabiana de Souza Marinho, Anna Letícia de Sousa Gualberto , Márcia Araújo Sousa , Ian Jhemes Oliveira Gonçalves, Rodrigo Lopes Gomes Silva, Kelly Maria Rêgo da Pinheiro, Iluska Martins |
dc.subject.por.fl_str_mv |
Tratamento Farmacológico Endometriose Terapia combinada. Pharmacological Treatment Endometriosis Combined therapy. Tratamiento farmacológico Endometriosis Terapia combinada. |
topic |
Tratamento Farmacológico Endometriose Terapia combinada. Pharmacological Treatment Endometriosis Combined therapy. Tratamiento farmacológico Endometriosis Terapia combinada. |
description |
Endometriosis is a gynecological disease characterized by the presence of endometrium as tissue-epithelium and stroma that develops outside the uterine cavity. It is a chronic, estrogen-dependent disease, is associated with pelvic pain, dysmenorrhea, dyspareunia and infertility. Given the great impact of this disease on the quality of life of women, there has been a growing interest in the discovery of new drugs that are more effective, tolerability and safety. For this, a literature review was carried out from articles published between 2008 and 2018 available regarding pharmacological treatments for endometriosis in the SCIENCE DIRECT and PUBMED databases. A total of 223 articles published in the last 10 years were found in "Portuguese and English". After evaluating the articles, 15 articles were selected for the present study, which complied with all the eligibility criteria proposed in the methodology. It was concluded that we can count on several types of treatments for endometriosis, but most have the objective of treating the symptoms associated with endometriosis. Currently, the specific treatment we can count on is dienogeste. In addition, there are many studies in search of new drugs and promising treatments for this pathology. Thus, more research is needed regarding the theme and that the pharmacist plays a fundamental role in the adherence to the patient's treatment. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/16104 10.33448/rsd-v10i7.16104 |
url |
https://rsdjournal.org/index.php/rsd/article/view/16104 |
identifier_str_mv |
10.33448/rsd-v10i7.16104 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/16104/15091 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 7; e52810716104 Research, Society and Development; Vol. 10 Núm. 7; e52810716104 Research, Society and Development; v. 10 n. 7; e52810716104 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1822178499817897984 |
dc.identifier.doi.none.fl_str_mv |
10.33448/rsd-v10i7.16104 |