Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy

Detalhes bibliográficos
Autor(a) principal: Corrêa, Janaina Maria Xavier
Data de Publicação: 2022
Outros Autores: Niella, Raquel Vieira, Oliveira, Jéssica Natália Silva de, Marques, Claire Souza da Costa, Silva, Elisângela Barboza da, Beier, Suzane Lilian, Silva, Fabiana Lessa, Lavor, Mário Sérgio Lima de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/29612
Resumo: The present study aimed to evaluate the efficacy of epidural maropitant administered with or without lidocaine for post-operative analgesia in cats. Forty cats submitted to epidural administration of treatments followed by ovariohysterectomy were assessed in this study. The cats were randomly distributed into experimental groups: epidural control group (ECG), which received saline; epidural lidocaine group (ELG), which received 3 mg/kg of 2% lidocaine without vasoconstrictor; epidural maropitant group (EMG), which received 1 mg/kg of maropitant; and epidural lidocaine and maropitant group (ELMG), which received 3 mg/kg of 2% lidocaine without vasoconstrictor and 1 mg/kg of maropitant. In all groups, sacrococcygeal epidural administration was performed. Physiological variables were measured during the surgical procedure. Post-operative pain was assessed over six hours by using a visual analogue scale and a multidimensional scale for assessment of post-operative pain in cats. During the surgical procedure, the heart rate in the ELMG was lower than that in the EMG. The ECG required a higher quantity of rescue analgesia in the post-operative period. The EMG and ELMG showed lower pain scores than the ECG. Epidural administration of lidocaine and maropitant, alone or in combination, provided similar analgesic effects in the post-operative period. Although the results indicate analgesic effects of lidocaine and maropitant used alone for two hours and the combination for three hours, the clinical use is limited because the duration of analgesia is too short for postoperative analgesia.
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spelling Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy Efecto analgésico del maropitant epidural y la combinación de maropitant y lidocaína en gatas sometidas a ovariohisterectomíaEfeito analgésico do maropitant e da combinação de maropitant e lidocaína por via epidural em gatas submetidas à ovariohisterectomiaAntagonista de receptor neurocinina 1Ensino em saúdeNocicepçãoDor.Antagonista del receptor de neuroquinina-1Enseñanza en la saludNocicepciónDolor.Antagonist neurokinin-1 receptorHealth teachingNociceptionPain.The present study aimed to evaluate the efficacy of epidural maropitant administered with or without lidocaine for post-operative analgesia in cats. Forty cats submitted to epidural administration of treatments followed by ovariohysterectomy were assessed in this study. The cats were randomly distributed into experimental groups: epidural control group (ECG), which received saline; epidural lidocaine group (ELG), which received 3 mg/kg of 2% lidocaine without vasoconstrictor; epidural maropitant group (EMG), which received 1 mg/kg of maropitant; and epidural lidocaine and maropitant group (ELMG), which received 3 mg/kg of 2% lidocaine without vasoconstrictor and 1 mg/kg of maropitant. In all groups, sacrococcygeal epidural administration was performed. Physiological variables were measured during the surgical procedure. Post-operative pain was assessed over six hours by using a visual analogue scale and a multidimensional scale for assessment of post-operative pain in cats. During the surgical procedure, the heart rate in the ELMG was lower than that in the EMG. The ECG required a higher quantity of rescue analgesia in the post-operative period. The EMG and ELMG showed lower pain scores than the ECG. Epidural administration of lidocaine and maropitant, alone or in combination, provided similar analgesic effects in the post-operative period. Although the results indicate analgesic effects of lidocaine and maropitant used alone for two hours and the combination for three hours, the clinical use is limited because the duration of analgesia is too short for postoperative analgesia.El presente estudio tuvo como objetivo evaluar la eficacia del maropitant epidural administrado con o sin lidocaína para la analgesia postoperatoria en gatos. En este estudio se evaluaron cuarenta gatos sometidos a tratamiento epidural seguido de ovariohisterectomía. Los gatos fueron asignados aleatoriamente a grupos experimentales: el grupo de control epidural (GCE) recibió solución salina; el grupo de lidocaína epidural (GLE) recibió 3 mg/kg de lidocaína al 2% sin vasoconstrictor; el grupo de maropitant epidural (GME) recibió 1 mg/kg de maropitant; y el grupo de lidocaína epidural y maropitant (GLEM) recibió 3 mg/kg de lidocaína al 2% sin vasoconstrictor y 1 mg/kg de maropitant. En todos los grupos se realizó administración epidural sacrococcígea. Las variables fisiológicas se midieron durante el procedimiento quirúrgico. El dolor posoperatorio se evaluó durante seis horas utilizando una escala analógica visual y una escala multidimensional para evaluar el dolor posoperatorio en gatos. Durante el procedimiento quirúrgico, la frecuencia cardíaca en el GLEM fue menor que en el GME. El GCE requirió mayor cantidad de analgesia de rescate postoperatoria. El GME y el GLEM tuvieron puntuaciones de dolor más bajas que el GCE. La administración epidural de lidocaína y maropitant, solos o en combinación, proporcionó efectos analgésicos posoperatorios similares. Aunque los resultados indican efectos analgésicos de la lidocaína y el maropitant usados ​​solos durante dos horas y en combinación durante tres horas, el uso clínico es limitado porque la duración de la analgesia es demasiado breve para la analgesia posoperatoria.O presente estudo teve como objetivo avaliar a eficácia do maropitant epidural administrado com ou sem lidocaína para analgesia pós-operatória em gatos. Quarenta gatas submetidas à tratamento com epidural seguida de ovariohisterectomia foram avaliadas neste estudo. As gatas foram distribuídos aleatoriamente em grupos experimentais: grupo controle epidural (GCE) recebeu solução salina; grupo lidocaína epidural (GLE) recebeu 3 mg/kg de lidocaína a 2% sem vasoconstritor; grupo maropitant epidural (GME) recebeu 1 mg/kg de maropitant; e grupo lidocaína epidural e maropitant (GLEM) recebeu 3 mg/kg de lidocaína a 2% sem vasoconstritor e 1 mg/kg de maropitant. Em todos os grupos foi realizada administração epidural sacrococcígea. As variáveis ​​fisiológicas foram mensuradas durante o procedimento cirúrgico. A dor pós-operatória foi avaliada ao longo de seis horas usando uma escala visual analógica e uma escala multidimensional para avaliação da dor pós-operatória em gatos. Durante o procedimento cirúrgico, a frequência cardíaca no GLEM foi menor do que no GME. O GCE exigiu maior quantidade de analgesia de resgate no pós-operatório. O GME e GLEM apresentaram escores de dor mais baixos do que o GCE. A administração epidural de lidocaína e maropitant, isoladamente ou em combinação, proporcionou efeitos analgésicos semelhantes no pós-operatório. Embora os resultados indiquem efeitos analgésicos da lidocaína e do maropitant usados isoladamente por duas horas e da combinação por três horas, o uso clínico é limitado porque a duração do tempo de analgesia é muito curta para analgesia pós-operatória.Research, Society and Development2022-05-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2961210.33448/rsd-v11i7.29612Research, Society and Development; Vol. 11 No. 7; e17511729612Research, Society and Development; Vol. 11 Núm. 7; e17511729612Research, Society and Development; v. 11 n. 7; e175117296122525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/29612/25749Copyright (c) 2022 Janaina Maria Xavier Corrêa; Raquel Vieira Niella; Jéssica Natália Silva de Oliveira; Claire Souza da Costa Marques; Elisângela Barboza da Silva; Suzane Lilian Beier; Fabiana Lessa Silva; Mário Sérgio Lima de Lavorhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCorrêa, Janaina Maria Xavier Niella, Raquel VieiraOliveira, Jéssica Natália Silva de Marques, Claire Souza da Costa Silva, Elisângela Barboza daBeier, Suzane Lilian Silva, Fabiana LessaLavor, Mário Sérgio Lima de2022-06-06T15:12:05Zoai:ojs.pkp.sfu.ca:article/29612Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:46:38.245276Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
Efecto analgésico del maropitant epidural y la combinación de maropitant y lidocaína en gatas sometidas a ovariohisterectomía
Efeito analgésico do maropitant e da combinação de maropitant e lidocaína por via epidural em gatas submetidas à ovariohisterectomia
title Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
spellingShingle Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
Corrêa, Janaina Maria Xavier
Antagonista de receptor neurocinina 1
Ensino em saúde
Nocicepção
Dor.
Antagonista del receptor de neuroquinina-1
Enseñanza en la salud
Nocicepción
Dolor.
Antagonist neurokinin-1 receptor
Health teaching
Nociception
Pain.
title_short Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
title_full Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
title_fullStr Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
title_full_unstemmed Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
title_sort Analgesic effect of epidural maropitant and the combination of maropitant and lidocaine in cats subjected to ovariohysterectomy
author Corrêa, Janaina Maria Xavier
author_facet Corrêa, Janaina Maria Xavier
Niella, Raquel Vieira
Oliveira, Jéssica Natália Silva de
Marques, Claire Souza da Costa
Silva, Elisângela Barboza da
Beier, Suzane Lilian
Silva, Fabiana Lessa
Lavor, Mário Sérgio Lima de
author_role author
author2 Niella, Raquel Vieira
Oliveira, Jéssica Natália Silva de
Marques, Claire Souza da Costa
Silva, Elisângela Barboza da
Beier, Suzane Lilian
Silva, Fabiana Lessa
Lavor, Mário Sérgio Lima de
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Corrêa, Janaina Maria Xavier
Niella, Raquel Vieira
Oliveira, Jéssica Natália Silva de
Marques, Claire Souza da Costa
Silva, Elisângela Barboza da
Beier, Suzane Lilian
Silva, Fabiana Lessa
Lavor, Mário Sérgio Lima de
dc.subject.por.fl_str_mv Antagonista de receptor neurocinina 1
Ensino em saúde
Nocicepção
Dor.
Antagonista del receptor de neuroquinina-1
Enseñanza en la salud
Nocicepción
Dolor.
Antagonist neurokinin-1 receptor
Health teaching
Nociception
Pain.
topic Antagonista de receptor neurocinina 1
Ensino em saúde
Nocicepção
Dor.
Antagonista del receptor de neuroquinina-1
Enseñanza en la salud
Nocicepción
Dolor.
Antagonist neurokinin-1 receptor
Health teaching
Nociception
Pain.
description The present study aimed to evaluate the efficacy of epidural maropitant administered with or without lidocaine for post-operative analgesia in cats. Forty cats submitted to epidural administration of treatments followed by ovariohysterectomy were assessed in this study. The cats were randomly distributed into experimental groups: epidural control group (ECG), which received saline; epidural lidocaine group (ELG), which received 3 mg/kg of 2% lidocaine without vasoconstrictor; epidural maropitant group (EMG), which received 1 mg/kg of maropitant; and epidural lidocaine and maropitant group (ELMG), which received 3 mg/kg of 2% lidocaine without vasoconstrictor and 1 mg/kg of maropitant. In all groups, sacrococcygeal epidural administration was performed. Physiological variables were measured during the surgical procedure. Post-operative pain was assessed over six hours by using a visual analogue scale and a multidimensional scale for assessment of post-operative pain in cats. During the surgical procedure, the heart rate in the ELMG was lower than that in the EMG. The ECG required a higher quantity of rescue analgesia in the post-operative period. The EMG and ELMG showed lower pain scores than the ECG. Epidural administration of lidocaine and maropitant, alone or in combination, provided similar analgesic effects in the post-operative period. Although the results indicate analgesic effects of lidocaine and maropitant used alone for two hours and the combination for three hours, the clinical use is limited because the duration of analgesia is too short for postoperative analgesia.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-20
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/29612
10.33448/rsd-v11i7.29612
url https://rsdjournal.org/index.php/rsd/article/view/29612
identifier_str_mv 10.33448/rsd-v11i7.29612
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/29612/25749
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 7; e17511729612
Research, Society and Development; Vol. 11 Núm. 7; e17511729612
Research, Society and Development; v. 11 n. 7; e17511729612
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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