Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review

Detalhes bibliográficos
Autor(a) principal: Bonfim, Lavínia Sampaio
Data de Publicação: 2022
Outros Autores: Moreno, Bruna Carvalho Lopez, Brito Junior, Anildo Alves de, Lima, Flávia Quadros, Dantas, Juliana Borges de Lima, Medrado, Alena Ribeiro Alves Peixoto
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/26673
Resumo: At the beginning of the COVID-19 pandemic, contact with the saliva infected was observed to represent a form of contagion possibly related to the anatomical proximity between the upper respiratory tract and the oral cavity. Studies seem to indicate that SARS-COV-2 can infect epithelial cells of the salivary glands, and impacts the clinical practice of dental surgeons. This study aimed to collect current evidence on the presence of SARS-CoV-2 in salivary glands, its detection through saliva, and discuss the relevance of this knowledge in clinical dental practice. A systematic review was conducted in the databases Pubmed, Lilacs, Google Schoolar, Scielo, Cochrane and Medline in the period from November/2020 to May/2021. PRISMA guidelines and the anagram PICO were adopted to characterize the selected studies according to the inclusion criteria, which comprised prospective studies, with full text available online in the English or Portuguese language and published from the year 2020. Among the 17 selected articles, 2 prospective studies evaluated the presence of SARS-CoV-2 in the parenchyma of salivary glands and all 16 papers found the presence of SARS-CoV-2 in saliva. The size of the studies varied according to the type of study, and the total number of participants was 3677. This study ratifies saliva as a route of transmission, and it is crucial that all health care workers use personal protective equipment and adhere strictly to biosafety regulations.
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spelling Detection of SARS-CoV-2 in saliva and salivary glands – a systematic reviewDetección de SARS-CoV-2 en saliva y glándulas salivales- una revisión sistemáticaDetecção de SARS-CoV-2 na saliva e em glândulas salivares – uma revisão sistemática Covid-19Glândula salivarSaliva e infecção.Covid-19Glándula salivalSaliva y infección.Covid-19Salivary glandSaliva and infection.At the beginning of the COVID-19 pandemic, contact with the saliva infected was observed to represent a form of contagion possibly related to the anatomical proximity between the upper respiratory tract and the oral cavity. Studies seem to indicate that SARS-COV-2 can infect epithelial cells of the salivary glands, and impacts the clinical practice of dental surgeons. This study aimed to collect current evidence on the presence of SARS-CoV-2 in salivary glands, its detection through saliva, and discuss the relevance of this knowledge in clinical dental practice. A systematic review was conducted in the databases Pubmed, Lilacs, Google Schoolar, Scielo, Cochrane and Medline in the period from November/2020 to May/2021. PRISMA guidelines and the anagram PICO were adopted to characterize the selected studies according to the inclusion criteria, which comprised prospective studies, with full text available online in the English or Portuguese language and published from the year 2020. Among the 17 selected articles, 2 prospective studies evaluated the presence of SARS-CoV-2 in the parenchyma of salivary glands and all 16 papers found the presence of SARS-CoV-2 in saliva. The size of the studies varied according to the type of study, and the total number of participants was 3677. This study ratifies saliva as a route of transmission, and it is crucial that all health care workers use personal protective equipment and adhere strictly to biosafety regulations.Ya la pandemia de COVID-19 se observó que el contacto con la saliva infectada representaba una forma de contagio relacionada con la proximidad anatómica entre el tracto respiratorio superior y la cavidad oral. Estudios indicar que el SARS-COV-2 puede infectar las células epiteliales de las glándulas salivales, con un profundo impacto en la práctica clínica de los cirujanos dentales. Este estudio tenía como objetivo recopilar las pruebas sobre la presencia del SARS-CoV-2 en las glándulas salivales, su detección a través de la saliva y discutir la relevancia de estos conocimientos en la práctica clínica dental. Esta revisión sistemática se realizó una búsqueda en las bases de datos Pubmed, Lilacs, Google Schoolar, Scielo, Cochrane y Medline en el periodo entre noviembre/2020 y mayo/2021. Se adoptaron las directrices PRISMA y el anagrama PICO para caracterizar los estudios según los criterios de inclusión, que comprendían estudios con texto completo disponible en inglés y portugués, publicados a partir del año 2020. Entre los 17 artículos seleccionados, 2 estudios evaluaron la presencia de SARS-CoV-2 en el parénquima de las glándulas salivales y los 16 trabajos encontraron la presencia de SARS-CoV-2 en la saliva. El tamaño de la muestra variaba según el tipo de estudio, y el número total de participantes era de 3.677. Este estudio ratifica que la saliva es una vía de transmisión y, por lo tanto, es crucial que todos los profesionales sanitarios utilicen equipos de protección personal y cumplan rigurosamente las normas de bioseguridad.No início da pandemia de COVID-19 foi observado que o contato com a saliva infectada representava uma forma de contágio possivelmente relacionada com a proximidade anatômica entre o trato respiratório superior e a cavidade oral. Estudos recentes indicam que o SARS-COV-2 pode infectar células epiteliais das glândulas salivares, o que impacta na prática clínica de cirurgiões-dentistas. O presente trabalho objetivou coletar evidências acerca da presença de SARS-CoV-2 em glândulas salivares, da sua detecção por meio da saliva e discutir a relevância deste conhecimento na prática clínica odontológica. Foi realizada uma revisão sistemática com busca nas bases de dados Pubmed, Lilacs, Google Schoolar, Scielo, Cochrane e Medline, no período entre novembro/2020 a maio/2021. Foram adotadas as diretrizes PRISMA e o anagrama PICO para caracterização dos estudos de acordo com os critérios de inclusão, que compreenderam estudos prospectivos sobre a temática, com texto completo online disponível em inglês ou português, e publicados a partir de 2020. Entre os 17 artigos selecionados, 2 estudos prospectivos avaliaram a presença de SARS-CoV-2 no parênquima de glândulas salivares e todos os 16 trabalhos constataram a presença de SARS-CoV-2 na saliva. O tamanho da amostra variou de acordo com o tipo de estudo, e o total de participantes foi 3677. Este estudo ratifica a saliva como uma via de transmissão e, sendo assim, é crucial que todos os profissionais de saúde utilizem os equipamentos de proteção individual e tenham rigor com as normas de biossegurança.Research, Society and Development2022-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2667310.33448/rsd-v11i3.26673Research, Society and Development; Vol. 11 No. 3; e45111326673Research, Society and Development; Vol. 11 Núm. 3; e45111326673Research, Society and Development; v. 11 n. 3; e451113266732525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26673/23431Copyright (c) 2022 Lavínia Sampaio Bonfim; Bruna Carvalho Lopez Moreno; Anildo Alves de Brito Junior; Flávia Quadros Lima; Juliana Borges de Lima Dantas; Alena Ribeiro Alves Peixoto Medradohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBonfim, Lavínia Sampaio Moreno, Bruna Carvalho LopezBrito Junior, Anildo Alves de Lima, Flávia QuadrosDantas, Juliana Borges de Lima Medrado, Alena Ribeiro Alves Peixoto 2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26673Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:39.267845Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
Detección de SARS-CoV-2 en saliva y glándulas salivales- una revisión sistemática
Detecção de SARS-CoV-2 na saliva e em glândulas salivares – uma revisão sistemática
title Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
spellingShingle Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
Bonfim, Lavínia Sampaio
Covid-19
Glândula salivar
Saliva e infecção.
Covid-19
Glándula salival
Saliva y infección.
Covid-19
Salivary gland
Saliva and infection.
title_short Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
title_full Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
title_fullStr Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
title_full_unstemmed Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
title_sort Detection of SARS-CoV-2 in saliva and salivary glands – a systematic review
author Bonfim, Lavínia Sampaio
author_facet Bonfim, Lavínia Sampaio
Moreno, Bruna Carvalho Lopez
Brito Junior, Anildo Alves de
Lima, Flávia Quadros
Dantas, Juliana Borges de Lima
Medrado, Alena Ribeiro Alves Peixoto
author_role author
author2 Moreno, Bruna Carvalho Lopez
Brito Junior, Anildo Alves de
Lima, Flávia Quadros
Dantas, Juliana Borges de Lima
Medrado, Alena Ribeiro Alves Peixoto
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Bonfim, Lavínia Sampaio
Moreno, Bruna Carvalho Lopez
Brito Junior, Anildo Alves de
Lima, Flávia Quadros
Dantas, Juliana Borges de Lima
Medrado, Alena Ribeiro Alves Peixoto
dc.subject.por.fl_str_mv Covid-19
Glândula salivar
Saliva e infecção.
Covid-19
Glándula salival
Saliva y infección.
Covid-19
Salivary gland
Saliva and infection.
topic Covid-19
Glândula salivar
Saliva e infecção.
Covid-19
Glándula salival
Saliva y infección.
Covid-19
Salivary gland
Saliva and infection.
description At the beginning of the COVID-19 pandemic, contact with the saliva infected was observed to represent a form of contagion possibly related to the anatomical proximity between the upper respiratory tract and the oral cavity. Studies seem to indicate that SARS-COV-2 can infect epithelial cells of the salivary glands, and impacts the clinical practice of dental surgeons. This study aimed to collect current evidence on the presence of SARS-CoV-2 in salivary glands, its detection through saliva, and discuss the relevance of this knowledge in clinical dental practice. A systematic review was conducted in the databases Pubmed, Lilacs, Google Schoolar, Scielo, Cochrane and Medline in the period from November/2020 to May/2021. PRISMA guidelines and the anagram PICO were adopted to characterize the selected studies according to the inclusion criteria, which comprised prospective studies, with full text available online in the English or Portuguese language and published from the year 2020. Among the 17 selected articles, 2 prospective studies evaluated the presence of SARS-CoV-2 in the parenchyma of salivary glands and all 16 papers found the presence of SARS-CoV-2 in saliva. The size of the studies varied according to the type of study, and the total number of participants was 3677. This study ratifies saliva as a route of transmission, and it is crucial that all health care workers use personal protective equipment and adhere strictly to biosafety regulations.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26673
10.33448/rsd-v11i3.26673
url https://rsdjournal.org/index.php/rsd/article/view/26673
identifier_str_mv 10.33448/rsd-v11i3.26673
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26673/23431
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 3; e45111326673
Research, Society and Development; Vol. 11 Núm. 3; e45111326673
Research, Society and Development; v. 11 n. 3; e45111326673
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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