Epigenetic changes in autismo spectrum disorder: na integrative literature review

• Autor(a) principal: Correia, Thays Lorena Bahia Vieira
• Data de Publicação: 2021
• Outros Autores: Cunha, Tatiana Fernanda Queiroz, Andrade, Eduarda Rafaella Resende, Santos, Regina Consolação dos, Maciel, Erika Augusta Faria, Silva, Fernanda Marcelino Rezende e, Pena, Liliane, Carvalho, Thayane Vieira, Pena, Heber Paulino
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• DOI: 10.33448/rsd-v10i11.19449
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/19449
• topic: Cambios genéticos; Trastornos epigenéticos; Trastorno del espectro autista; Herencia multifactorial.; Transtorno de Espectro Autista; Alterações Genéticas; Desordens Epigenéticas; Herança multifatorial.; Autistic Spectrum Disorder; Genetic Changes; Epigenetic Disorders; Multifactorial inheritance.

Autism spectrum disorder (ASD) is a disorder that affects children's neurodevelopment and makes their capacity for social and intellectual interaction and behavior less developed. The aim of this study was to show how epigenetic disorders can contribute to the emergence of autistic children, demonstrating how essential it is to carry out scientific research and seek to understand the epigenetic characteristics that lead to the development of ASD. The study seeks to carry out an integrative literature review and has as descriptors: "autistic spectrum disorder and epigenetic disorders", "autism", "epigenetic disorders", "autism spectrum disorder and epigenetic disorders", "autism", "autism spectrum disorder”, “epigenetics disorders”, the databases consulted were Pubmed, Scientific Electronic Library Online (Scielo) and Academic Google. Studies show that ASD is characterized as a multifactorial inheritance disorder and that environmental factors, whether independent or in conjunction with epigenetic factors, increase the risk of this condition. We conclude that epigenetic alterations are associated with autism, as well as the behavioral and histological consequences of this disorder.