Epigenetic changes in autismo spectrum disorder: na integrative literature review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/19449 |
Resumo: | Autism spectrum disorder (ASD) is a disorder that affects children's neurodevelopment and makes their capacity for social and intellectual interaction and behavior less developed. The aim of this study was to show how epigenetic disorders can contribute to the emergence of autistic children, demonstrating how essential it is to carry out scientific research and seek to understand the epigenetic characteristics that lead to the development of ASD. The study seeks to carry out an integrative literature review and has as descriptors: "autistic spectrum disorder and epigenetic disorders", "autism", "epigenetic disorders", "autism spectrum disorder and epigenetic disorders", "autism", "autism spectrum disorder”, “epigenetics disorders”, the databases consulted were Pubmed, Scientific Electronic Library Online (Scielo) and Academic Google. Studies show that ASD is characterized as a multifactorial inheritance disorder and that environmental factors, whether independent or in conjunction with epigenetic factors, increase the risk of this condition. We conclude that epigenetic alterations are associated with autism, as well as the behavioral and histological consequences of this disorder. |
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Epigenetic changes in autismo spectrum disorder: na integrative literature reviewCambios epigenéticos en el transtorno del espectro autista: una revisión integradora de la literaturaAlterações epigenéticas no transtorno do espectro autista: revisão integrativa de literaturaCambios genéticosTrastornos epigenéticosTrastorno del espectro autistaHerencia multifactorial.Transtorno de Espectro AutistaAlterações GenéticasDesordens EpigenéticasHerança multifatorial.Autistic Spectrum DisorderGenetic ChangesEpigenetic DisordersMultifactorial inheritance.Autism spectrum disorder (ASD) is a disorder that affects children's neurodevelopment and makes their capacity for social and intellectual interaction and behavior less developed. The aim of this study was to show how epigenetic disorders can contribute to the emergence of autistic children, demonstrating how essential it is to carry out scientific research and seek to understand the epigenetic characteristics that lead to the development of ASD. The study seeks to carry out an integrative literature review and has as descriptors: "autistic spectrum disorder and epigenetic disorders", "autism", "epigenetic disorders", "autism spectrum disorder and epigenetic disorders", "autism", "autism spectrum disorder”, “epigenetics disorders”, the databases consulted were Pubmed, Scientific Electronic Library Online (Scielo) and Academic Google. Studies show that ASD is characterized as a multifactorial inheritance disorder and that environmental factors, whether independent or in conjunction with epigenetic factors, increase the risk of this condition. We conclude that epigenetic alterations are associated with autism, as well as the behavioral and histological consequences of this disorder.El trastorno del espectro autista (TEA) es un trastorno que afecta el desarrollo neurológico de los niños y hace que su capacidad de interacción social e intelectual y su comportamiento estén menos desarrollados. El objetivo de este estudio fue mostrar cómo los trastornos epigenéticos pueden contribuir a la aparición de niños autistas, demostrando lo fundamental que es realizar investigaciones científicas y buscar comprender las características epigenéticas que conducen al desarrollo de los TEA. El estudio busca realizar una revisión integradora de la literatura y tiene como descriptores: "trastorno del espectro autista y trastornos epigenéticos", "autismo", "trastornos epigenéticos", "trastorno del espectro autista y trastornos epigenéticos", "autismo", "trastorno del espectro autista". ”,“ Trastornos de la epigenética ”, las bases de datos consultadas fueron Pubmed, Scientific Electronic Library Online (Scielo) y Academic Google. Los estudios muestran que el TEA se caracteriza como un trastorno hereditario multifactorial y que los factores ambientales, ya sean independientes o en conjunto con factores epigenéticos, aumentan el riesgo de padecer esta afección. Concluimos que las alteraciones epigenéticas están asociadas al autismo, así como las consecuencias conductuales e histológicas de este trastorno.O transtorno de espectro autista (TEA) é um distúrbio que afeta o neurodesenvolvimento da criança e faz com que sua capacidade de interação social, intelectual e seu comportamento sejam menos desenvolvidos. O objetivo desse estudo foi evidenciar como as desordens epigenéticas podem contribuir para o surgimento de crianças autistas, demonstrando como é essencial que se faça pesquisas científicas e busque compreender as características epigenéticas que levam ao desenvolvimento do TEA. O estudo busca realizar uma revisão integrativa de literatura e tem como descritores: “transtorno do espectro autista e as desordens epigenéticas”, “autismo”, “desordens epigenéticas”, “autism spectrum disorder and epigenetic disorders”, “autism”, “autism spectrum disorder”, “disorders epigenetics”, a base de dados consultados foram a Pubmed, Scientific Eletronic Library Online (Scielo) e Google acadêmico. Os estudos apontam que o TEA é caracterizado como um transtorno de herança multifatorial e que fatores ambientais, independentes ou em conjunto com os fatores epigenéticos, aumentam o risco desse agravo. Concluímos que as alterações epigenéticas estão associadas ao autismo, assim como as consequências comportamentais e histológicas deste distúrbio.Research, Society and Development2021-09-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1944910.33448/rsd-v10i11.19449Research, Society and Development; Vol. 10 No. 11; e369101119449Research, Society and Development; Vol. 10 Núm. 11; e369101119449Research, Society and Development; v. 10 n. 11; e3691011194492525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/19449/17624Copyright (c) 2021 Thays Lorena Bahia Vieira Correia; Tatiana Fernanda Queiroz Cunha; Eduarda Rafaella Resende Andrade; Regina Consolação dos Santos; Erika Augusta Faria Maciel; Fernanda Marcelino Rezende e Silva; Liliane Pena; Thayane Vieira Carvalho; Heber Paulino Penahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCorreia, Thays Lorena Bahia Vieira Cunha, Tatiana Fernanda Queiroz Andrade, Eduarda Rafaella Resende Santos, Regina Consolação dos Maciel, Erika Augusta Faria Silva, Fernanda Marcelino Rezende e Pena, LilianeCarvalho, Thayane Vieira Pena, Heber Paulino 2021-10-23T19:01:11Zoai:ojs.pkp.sfu.ca:article/19449Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:39:20.439926Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Epigenetic changes in autismo spectrum disorder: na integrative literature review Cambios epigenéticos en el transtorno del espectro autista: una revisión integradora de la literatura Alterações epigenéticas no transtorno do espectro autista: revisão integrativa de literatura |
| title |
Epigenetic changes in autismo spectrum disorder: na integrative literature review |
| spellingShingle |
Epigenetic changes in autismo spectrum disorder: na integrative literature review Correia, Thays Lorena Bahia Vieira Cambios genéticos Trastornos epigenéticos Trastorno del espectro autista Herencia multifactorial. Transtorno de Espectro Autista Alterações Genéticas Desordens Epigenéticas Herança multifatorial. Autistic Spectrum Disorder Genetic Changes Epigenetic Disorders Multifactorial inheritance. |
| title_short |
Epigenetic changes in autismo spectrum disorder: na integrative literature review |
| title_full |
Epigenetic changes in autismo spectrum disorder: na integrative literature review |
| title_fullStr |
Epigenetic changes in autismo spectrum disorder: na integrative literature review |
| title_full_unstemmed |
Epigenetic changes in autismo spectrum disorder: na integrative literature review |
| title_sort |
Epigenetic changes in autismo spectrum disorder: na integrative literature review |
| author |
Correia, Thays Lorena Bahia Vieira |
| author_facet |
Correia, Thays Lorena Bahia Vieira Cunha, Tatiana Fernanda Queiroz Andrade, Eduarda Rafaella Resende Santos, Regina Consolação dos Maciel, Erika Augusta Faria Silva, Fernanda Marcelino Rezende e Pena, Liliane Carvalho, Thayane Vieira Pena, Heber Paulino |
| author_role |
author |
| author2 |
Cunha, Tatiana Fernanda Queiroz Andrade, Eduarda Rafaella Resende Santos, Regina Consolação dos Maciel, Erika Augusta Faria Silva, Fernanda Marcelino Rezende e Pena, Liliane Carvalho, Thayane Vieira Pena, Heber Paulino |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Correia, Thays Lorena Bahia Vieira Cunha, Tatiana Fernanda Queiroz Andrade, Eduarda Rafaella Resende Santos, Regina Consolação dos Maciel, Erika Augusta Faria Silva, Fernanda Marcelino Rezende e Pena, Liliane Carvalho, Thayane Vieira Pena, Heber Paulino |
| dc.subject.por.fl_str_mv |
Cambios genéticos Trastornos epigenéticos Trastorno del espectro autista Herencia multifactorial. Transtorno de Espectro Autista Alterações Genéticas Desordens Epigenéticas Herança multifatorial. Autistic Spectrum Disorder Genetic Changes Epigenetic Disorders Multifactorial inheritance. |
| topic |
Cambios genéticos Trastornos epigenéticos Trastorno del espectro autista Herencia multifactorial. Transtorno de Espectro Autista Alterações Genéticas Desordens Epigenéticas Herança multifatorial. Autistic Spectrum Disorder Genetic Changes Epigenetic Disorders Multifactorial inheritance. |
| description |
Autism spectrum disorder (ASD) is a disorder that affects children's neurodevelopment and makes their capacity for social and intellectual interaction and behavior less developed. The aim of this study was to show how epigenetic disorders can contribute to the emergence of autistic children, demonstrating how essential it is to carry out scientific research and seek to understand the epigenetic characteristics that lead to the development of ASD. The study seeks to carry out an integrative literature review and has as descriptors: "autistic spectrum disorder and epigenetic disorders", "autism", "epigenetic disorders", "autism spectrum disorder and epigenetic disorders", "autism", "autism spectrum disorder”, “epigenetics disorders”, the databases consulted were Pubmed, Scientific Electronic Library Online (Scielo) and Academic Google. Studies show that ASD is characterized as a multifactorial inheritance disorder and that environmental factors, whether independent or in conjunction with epigenetic factors, increase the risk of this condition. We conclude that epigenetic alterations are associated with autism, as well as the behavioral and histological consequences of this disorder. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-09-04 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/19449 10.33448/rsd-v10i11.19449 |
| url |
https://rsdjournal.org/index.php/rsd/article/view/19449 |
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10.33448/rsd-v10i11.19449 |
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por |
| language |
por |
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https://rsdjournal.org/index.php/rsd/article/view/19449/17624 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 10 No. 11; e369101119449 Research, Society and Development; Vol. 10 Núm. 11; e369101119449 Research, Society and Development; v. 10 n. 11; e369101119449 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1797052687645147136 |