Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Dayane Adenir Shizuko Takata
Data de Publicação: 2020
Outros Autores: Toledo, Caroline Rossati, Zardeto-Sabec, Giuliana
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/10113
Resumo: Introduction: The ectopic pancreas (PE) consists of a congenital malformation, considered rare, defined as the presence of a pancreatic tissue outside its usual topographic location, with a ductal system and independent vascularization. The vast majority of PE cases are asymptomatic, but when the patient is symptomatic, it can manifest itself through bleeding, inflammation, obstruction of adjacent anatomical structures, complications such as pancreatitis and malignant transformations such as adenocarcinoma. Objective: Therefore, the objective of the present study was to carry out a review of cases of pancreatic ectopia and pancreatitis associated with ectopic pancreas, as well as a diagnostic and therapeutic approach when suspected of this disease. Metodology: To this end, an integrative review was developed of studies that address the theme of ectopic pancreas, including a retrospective approach to clinical cases published from 2009 to 2017. The databases consulted for this research were: LILACS (Latin American and Caribbean Literature in Health Sciences), the SciELO library (Scientific Electronic Library on Line) and PubMed (National Center for Biotechnology Information - NCBI, US National Library of Medicine), Google Scholar®. Results and discussion: It is a disease with an approximate incidence of 0.5% -15% in autopsies and 1 in 500 abdominal surgeries. Based on a study with 11,265 patients, 24 (0.21%) abdominal heterotopias were found, of which pancreatic was the most common (0.12%). Conclusion: In this sense, it is concluded that PE is a rare, congenital malformation; most patients have an asymptomatic evolution, however, when present, the symptoms are nonspecific, which makes the diagnosis difficult, being made through radiological exams, endoscopy of the digestive tract or through incidental surgical findings. It is suggested that further studies on the subject are needed for the patient to be diagnosed and treated quickly.
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spelling Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approachPáncreas ectópico: revisión de casos clínicos, abordaje diagnóstico y terapêuticoPâncreas ectópico: revisão de casos clínicos, abordagem diagnóstica e terapêuticaMalformación congénita raraHeterotopía pancreáticaPancreatitis.Rare congenital malformationPancreatic heterotopiaPancreatitis.Malformação congênita raraHeterotopia pancreáticaPancreatite.Introduction: The ectopic pancreas (PE) consists of a congenital malformation, considered rare, defined as the presence of a pancreatic tissue outside its usual topographic location, with a ductal system and independent vascularization. The vast majority of PE cases are asymptomatic, but when the patient is symptomatic, it can manifest itself through bleeding, inflammation, obstruction of adjacent anatomical structures, complications such as pancreatitis and malignant transformations such as adenocarcinoma. Objective: Therefore, the objective of the present study was to carry out a review of cases of pancreatic ectopia and pancreatitis associated with ectopic pancreas, as well as a diagnostic and therapeutic approach when suspected of this disease. Metodology: To this end, an integrative review was developed of studies that address the theme of ectopic pancreas, including a retrospective approach to clinical cases published from 2009 to 2017. The databases consulted for this research were: LILACS (Latin American and Caribbean Literature in Health Sciences), the SciELO library (Scientific Electronic Library on Line) and PubMed (National Center for Biotechnology Information - NCBI, US National Library of Medicine), Google Scholar®. Results and discussion: It is a disease with an approximate incidence of 0.5% -15% in autopsies and 1 in 500 abdominal surgeries. Based on a study with 11,265 patients, 24 (0.21%) abdominal heterotopias were found, of which pancreatic was the most common (0.12%). Conclusion: In this sense, it is concluded that PE is a rare, congenital malformation; most patients have an asymptomatic evolution, however, when present, the symptoms are nonspecific, which makes the diagnosis difficult, being made through radiological exams, endoscopy of the digestive tract or through incidental surgical findings. It is suggested that further studies on the subject are needed for the patient to be diagnosed and treated quickly.Introducción: El páncreas ectópico (EP) consiste en una malformación congénita, considerada rara, definida como la presencia de un tejido pancreático fuera de su localización topográfica habitual, con sistema ductal y vascularización independiente. La gran mayoría de los casos de TEP son asintomáticos, pero cuando el paciente es sintomático puede manifestarse por sangrado, inflamación, obstrucción de estructuras anatómicas adyacentes, complicaciones como pancreatitis y transformaciones malignas como el adenocarcinoma. Objetivo: Por tanto, el objetivo del presente estudio fue realizar una revisión de los casos de ectopia pancreática y pancreatitis asociada a páncreas ectópico, así como un abordaje diagnóstico y terapéutico ante la sospecha de esta enfermedad. Metodología: Para ello, se desarrolló una revisión integradora de estudios que abordan la temática del páncreas ectópico, incluyendo un abordaje retrospectivo de los casos clínicos publicados de 2009 a 2017. Las bases de datos consultadas para esta investigación fueron: LILACS (Literatura Latinoamericana y Caribeña en Ciencias) da Saúde), la biblioteca SciELO (Scientific Electronic Library on Line) y PubMed (National Center for Biotechnology Information - NCBI, US National Library of Medicine), Google academic®. Resultados y discusión: Es una enfermedad con una incidencia aproximada del 0,5% -15% en autopsias y 1 de cada 500 cirugías abdominales. En base a un estudio con 11 265 pacientes, se encontraron 24 (0,21%) heterotopias abdominales, de las cuales la pancreática fue la más frecuente (0,12%). Conclusión: En este sentido, se concluye que la EP es una malformación congénita rara; la mayoría de los pacientes tienen una evolución asintomática, sin embargo, cuando se presentan, los síntomas son inespecíficos, lo que dificulta el diagnóstico, realizándose mediante exámenes radiológicos, endoscopia del tracto digestivo o mediante hallazgos quirúrgicos incidentales. Se sugiere que se necesitan más estudios sobre el tema para que el paciente sea diagnosticado y tratado rápidamente.Introdução: O pâncreas ectópico (PE) consiste em uma malformação congênita, considerada rara, definida como a presença de um tecido pancreático fora da sua localização topográfica habitual, com sistema ductal e vascularização independente. A grande maioria dos casos de PE são assintomáticos, porém quando o paciente é sintomático, pode manifestar-se através de hemorragias, inflamações, obstruções de estruturas anatômicas adjacentes, complicações como a pancreatite e transformações malignas como o adenocarcinoma. Objetivo: Sendo assim, o objetivo do presente trabalho foi de realizar uma revisão a respeito de casos de ectopia pancreática e pancreatite associada a pâncreas ectópico, bem como abordagem diagnóstica e terapêutica perante a suspeita dessa enfermidade. Metodologia: Para isso, foi desenvolvido uma revisão integrativa, de estudos que abordam a temática pâncreas ectópico, incluindo abordagem retrospectiva de casos clínicos publicados desde 2009 até 2017. As bases de dados consultadas para esta pesquisa foram: LILACS (Literatura Latino Americana e do Caribe em Ciências da Saúde), a biblioteca SciELO (Scientific Electronic Library on Line) e PubMed (National Center for Biotechnology Information - NCBI, U.S. National Library of Medicine), Google acadêmico®. Resultados e discussão: Trata-se de uma doença com incidência aproximada de 0,5%-15% em autópsias e de 1 a cada 500 cirurgias abdominais. Com base em um estudo com 11.265 pacientes verificou-se 24 (0,21%) heterotopias abdominais, das quais a pancreática foi a mais comum (0,12%). Conclusão: Neste sentido, conclui-se que o PE é uma malformação congênita, rara; a maioria dos pacientes possui evolução assintomática, porém, quando presentes, os sintomas são inespecíficos, o que torna o diagnóstico difícil, sendo este realizado através de exames radiológicos, endoscopia do trato digestivo ou através de achados cirúrgicos incidentais. Sugere-se que mais estudos acerca do assunto são necessários para que o paciente seja diagnosticado e tratado rapidamente.Research, Society and Development2020-11-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1011310.33448/rsd-v9i11.10113Research, Society and Development; Vol. 9 No. 11; e44591110113Research, Society and Development; Vol. 9 Núm. 11; e44591110113Research, Society and Development; v. 9 n. 11; e445911101132525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/10113/8982Copyright (c) 2020 Dayane Adenir Shizuko Takata Ribeiro; Caroline Rossati Toledo; Giuliana Zardeto-Sabechttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRibeiro, Dayane Adenir Shizuko Takata Toledo, Caroline Rossati Zardeto-Sabec, Giuliana2020-12-10T23:37:57Zoai:ojs.pkp.sfu.ca:article/10113Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:32:14.615850Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
Páncreas ectópico: revisión de casos clínicos, abordaje diagnóstico y terapêutico
Pâncreas ectópico: revisão de casos clínicos, abordagem diagnóstica e terapêutica
title Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
spellingShingle Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
Ribeiro, Dayane Adenir Shizuko Takata
Malformación congénita rara
Heterotopía pancreática
Pancreatitis.
Rare congenital malformation
Pancreatic heterotopia
Pancreatitis.
Malformação congênita rara
Heterotopia pancreática
Pancreatite.
title_short Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
title_full Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
title_fullStr Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
title_full_unstemmed Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
title_sort Ectopic pancreas: review of clinical cases, diagnostic and therapeutic approach
author Ribeiro, Dayane Adenir Shizuko Takata
author_facet Ribeiro, Dayane Adenir Shizuko Takata
Toledo, Caroline Rossati
Zardeto-Sabec, Giuliana
author_role author
author2 Toledo, Caroline Rossati
Zardeto-Sabec, Giuliana
author2_role author
author
dc.contributor.author.fl_str_mv Ribeiro, Dayane Adenir Shizuko Takata
Toledo, Caroline Rossati
Zardeto-Sabec, Giuliana
dc.subject.por.fl_str_mv Malformación congénita rara
Heterotopía pancreática
Pancreatitis.
Rare congenital malformation
Pancreatic heterotopia
Pancreatitis.
Malformação congênita rara
Heterotopia pancreática
Pancreatite.
topic Malformación congénita rara
Heterotopía pancreática
Pancreatitis.
Rare congenital malformation
Pancreatic heterotopia
Pancreatitis.
Malformação congênita rara
Heterotopia pancreática
Pancreatite.
description Introduction: The ectopic pancreas (PE) consists of a congenital malformation, considered rare, defined as the presence of a pancreatic tissue outside its usual topographic location, with a ductal system and independent vascularization. The vast majority of PE cases are asymptomatic, but when the patient is symptomatic, it can manifest itself through bleeding, inflammation, obstruction of adjacent anatomical structures, complications such as pancreatitis and malignant transformations such as adenocarcinoma. Objective: Therefore, the objective of the present study was to carry out a review of cases of pancreatic ectopia and pancreatitis associated with ectopic pancreas, as well as a diagnostic and therapeutic approach when suspected of this disease. Metodology: To this end, an integrative review was developed of studies that address the theme of ectopic pancreas, including a retrospective approach to clinical cases published from 2009 to 2017. The databases consulted for this research were: LILACS (Latin American and Caribbean Literature in Health Sciences), the SciELO library (Scientific Electronic Library on Line) and PubMed (National Center for Biotechnology Information - NCBI, US National Library of Medicine), Google Scholar®. Results and discussion: It is a disease with an approximate incidence of 0.5% -15% in autopsies and 1 in 500 abdominal surgeries. Based on a study with 11,265 patients, 24 (0.21%) abdominal heterotopias were found, of which pancreatic was the most common (0.12%). Conclusion: In this sense, it is concluded that PE is a rare, congenital malformation; most patients have an asymptomatic evolution, however, when present, the symptoms are nonspecific, which makes the diagnosis difficult, being made through radiological exams, endoscopy of the digestive tract or through incidental surgical findings. It is suggested that further studies on the subject are needed for the patient to be diagnosed and treated quickly.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/10113
10.33448/rsd-v9i11.10113
url https://rsdjournal.org/index.php/rsd/article/view/10113
identifier_str_mv 10.33448/rsd-v9i11.10113
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/10113/8982
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 11; e44591110113
Research, Society and Development; Vol. 9 Núm. 11; e44591110113
Research, Society and Development; v. 9 n. 11; e44591110113
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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