Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit

Detalhes bibliográficos
Autor(a) principal: Oliveira, Cinara Rejane Viana
Data de Publicação: 2022
Outros Autores: Boa Sorte, Ney Cristian Amaral
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/25941
Resumo: Neonatal sepsis is one of the leading causes of death in newborns. Prior knowledge of risk factors is essential to prevent morbidity and mortality. This study aims to characterize the observed risk factors and their relationship with the occurrence of death in newborns diagnosed with sepsis. A cross-sectional study was carried out with the analysis of 712 participants hospitalized from September 2018 to June 2020. 410 neonates were included, with a higher proportion being males, born with artificial delivery and low birth weight. The prevalence of death observed was 6.3%, occurring especially among those with moderate and extreme prematurity, those born to teenage mothers or mothers over forty, those with hyperthermia, low weight, bradycardia and longer hospital stays. There was a low frequency of blood cultures performed. Although there was no predominance of typical clinical findings of sepsis, such as hypothermia, changes in the leukogram, platelet count and CRP levels, the robust findings of a greater association of extreme low birth weight, hyperthermia and tachypnea to a higher frequency of death reinforce the quality of the data obtained.
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spelling Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care UnitCaracterización de factores de riesgo y ocurrencia de muerte en recién-nacidos con diagnóstico de sepsis neonatal en una Unidad de Cuidados Intensivos NeonatalesCaracterização dos fatores de risco e ocorrência de óbito em recém-nascidos com diagnóstico de sepse neonatal em uma Unidade de Terapia Intensiva NeonatalSepse neonatalFatores de riscoÓbito.Sepsis neonatalFactores de riesgoMuerte.Neonatal sepsisRisk factorsDeath.Neonatal sepsis is one of the leading causes of death in newborns. Prior knowledge of risk factors is essential to prevent morbidity and mortality. This study aims to characterize the observed risk factors and their relationship with the occurrence of death in newborns diagnosed with sepsis. A cross-sectional study was carried out with the analysis of 712 participants hospitalized from September 2018 to June 2020. 410 neonates were included, with a higher proportion being males, born with artificial delivery and low birth weight. The prevalence of death observed was 6.3%, occurring especially among those with moderate and extreme prematurity, those born to teenage mothers or mothers over forty, those with hyperthermia, low weight, bradycardia and longer hospital stays. There was a low frequency of blood cultures performed. Although there was no predominance of typical clinical findings of sepsis, such as hypothermia, changes in the leukogram, platelet count and CRP levels, the robust findings of a greater association of extreme low birth weight, hyperthermia and tachypnea to a higher frequency of death reinforce the quality of the data obtained.La sepsis neonatal es una de las principales causas de muerte en los recién nacidos. El conocimiento previo de los factores de riesgo es fundamental para prevenir la morbimortalidad. Este estudio tiene como objetivo caracterizar los factores de riesgo observados y su relación con la ocurrencia de muerte en recién nacidos con diagnóstico de sepsis. Se realizó un estudio transversal con el análisis de 712 participantes hospitalizados desde septiembre de 2018 hasta junio de 2020. Se incluyeron 410 neonatos, con una mayor proporción del sexo masculino, nacidos con parto artificial y bajo peso al nacer. La prevalencia de óbito observada fue del 6,3%, siendo significativa sobre todo entre aquellos con prematuridad moderada y extrema, los nacidos de madre adolescente y los mayores de 40 años, aquellos con hipertermia, bajo peso, bradicardia y estancias hospitalarias prolongadas. Hubo una baja frecuencia de hemocultivos realizados. Aunque no hubo predominio de hallazgos clínicos característicos de sepsis, como hipotermia, cambios en el leucograma, recuento de plaquetas y niveles de PCR, los hallazgos robustos de una mayor asociación de bajo peso extremo al nacer, hipertermia y taquipnea y una mayor frecuencia de muerte refuerzan la calidad de los datos obtenidos.A sepse neonatal é uma das principais causas de morte de recém-nascidos. O conhecimento prévio dos fatores de risco são fundamentais para prevenir a morbimortalidade. Este estudo tem como objetivo caracterizar os fatores de risco observados e sua relação com a ocorrência de óbito em recém-nascidos com diagnóstico de sepse. Realizou-se um estudo transversal com análise de 712 participantes internados no período de setembro de 2018 a junho de 2020. Foram incluídos 410 neonatos sendo de maior proporção os do sexo masculinos, nascidos com via de parto artificial e baixo peso. A prevalência de óbito observada foi de 6,3% sendo significativa especialmente entre os com prematuridade moderada e extrema, os nascidos de mães adolescentes ou com mais idade de 40 anos, os com hipertemia, baixo peso, bradicardia e maiores tempo de internamento. Encontrou-se uma baixa frequência de hemocultura realizadas. Embora não tenha sido observado predomínio dos achados clínicos característicos da sepse como hipotermia, alterações do leucograma, contagem de plaquetas e níveis de PCR, os achados robustos de maior associação de extremo baixo peso ao nascer, hipertermia e taquipneia a maior frequência de óbito reforçam a qualidade dos dados obtidos.Research, Society and Development2022-03-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2594110.33448/rsd-v11i3.25941Research, Society and Development; Vol. 11 No. 3; e7811325941Research, Society and Development; Vol. 11 Núm. 3; e7811325941Research, Society and Development; v. 11 n. 3; e78113259412525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/25941/23464Copyright (c) 2022 Cinara Rejane Viana Oliveira; Ney Cristian Amaral Boa Sortehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, Cinara Rejane Viana Boa Sorte, Ney Cristian Amaral 2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/25941Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:06.096611Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
Caracterización de factores de riesgo y ocurrencia de muerte en recién-nacidos con diagnóstico de sepsis neonatal en una Unidad de Cuidados Intensivos Neonatales
Caracterização dos fatores de risco e ocorrência de óbito em recém-nascidos com diagnóstico de sepse neonatal em uma Unidade de Terapia Intensiva Neonatal
title Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
spellingShingle Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
Oliveira, Cinara Rejane Viana
Sepse neonatal
Fatores de risco
Óbito.
Sepsis neonatal
Factores de riesgo
Muerte.
Neonatal sepsis
Risk factors
Death.
title_short Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
title_full Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
title_fullStr Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
title_full_unstemmed Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
title_sort Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit
author Oliveira, Cinara Rejane Viana
author_facet Oliveira, Cinara Rejane Viana
Boa Sorte, Ney Cristian Amaral
author_role author
author2 Boa Sorte, Ney Cristian Amaral
author2_role author
dc.contributor.author.fl_str_mv Oliveira, Cinara Rejane Viana
Boa Sorte, Ney Cristian Amaral
dc.subject.por.fl_str_mv Sepse neonatal
Fatores de risco
Óbito.
Sepsis neonatal
Factores de riesgo
Muerte.
Neonatal sepsis
Risk factors
Death.
topic Sepse neonatal
Fatores de risco
Óbito.
Sepsis neonatal
Factores de riesgo
Muerte.
Neonatal sepsis
Risk factors
Death.
description Neonatal sepsis is one of the leading causes of death in newborns. Prior knowledge of risk factors is essential to prevent morbidity and mortality. This study aims to characterize the observed risk factors and their relationship with the occurrence of death in newborns diagnosed with sepsis. A cross-sectional study was carried out with the analysis of 712 participants hospitalized from September 2018 to June 2020. 410 neonates were included, with a higher proportion being males, born with artificial delivery and low birth weight. The prevalence of death observed was 6.3%, occurring especially among those with moderate and extreme prematurity, those born to teenage mothers or mothers over forty, those with hyperthermia, low weight, bradycardia and longer hospital stays. There was a low frequency of blood cultures performed. Although there was no predominance of typical clinical findings of sepsis, such as hypothermia, changes in the leukogram, platelet count and CRP levels, the robust findings of a greater association of extreme low birth weight, hyperthermia and tachypnea to a higher frequency of death reinforce the quality of the data obtained.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-04
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/25941
10.33448/rsd-v11i3.25941
url https://rsdjournal.org/index.php/rsd/article/view/25941
identifier_str_mv 10.33448/rsd-v11i3.25941
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/25941/23464
dc.rights.driver.fl_str_mv Copyright (c) 2022 Cinara Rejane Viana Oliveira; Ney Cristian Amaral Boa Sorte
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Cinara Rejane Viana Oliveira; Ney Cristian Amaral Boa Sorte
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 3; e7811325941
Research, Society and Development; Vol. 11 Núm. 3; e7811325941
Research, Society and Development; v. 11 n. 3; e7811325941
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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