Integrative review on olfactory disfunctions caused by COVID-19
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/28384 |
Resumo: | The study aims to gather and synthesize scientific information related to olfactory dysfunctions caused by SARS-CoV-2 (COVID-19). This is an integrative literature review carried out from scientific journals published from August to December 2021. Original articles with systematic literature reviews, retrospective observational studies, prospective descriptive studies, case-control studies and meta-studies were included meta-analyses. It was concluded that symptoms related to olfactory dysfunctions caused by COVID-19 vary according to age, sex, genetics, stage of the disease and pre-existing comorbidities. The mechanism of action by the virus to promote sensory changes is still uncertain. The main evidence suggests viral dissemination through the olfactory cleft neuroepithelium, with consequent infiltration in the olfactory bulb or neural loss mechanism, with direct damage to the olfactory sensory neurons. Given the complexity of the infection caused by COVID-19 it is essential to continue thematic research, especially in relation to the new variants of SARS-CoV-2. |
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Integrative review on olfactory disfunctions caused by COVID-19Revisión integrativa sobre las disfunciones olfativas por COVID-19Revisão integrativa sobre disfunções olfatórias causadas pela COVID-19SARS-CoV-2Severe acute respiratory syndromeOlfactory dysfunctionHypogeusiaTeaching.SARS-CoV-2Síndrome respiratorio agudo severoDisfunción olfativaHipogeusiaEnseñanza.SARS-CoV-2Síndrome respiratória aguda graveDisfunção olfativaHipogeusiaEnsino. The study aims to gather and synthesize scientific information related to olfactory dysfunctions caused by SARS-CoV-2 (COVID-19). This is an integrative literature review carried out from scientific journals published from August to December 2021. Original articles with systematic literature reviews, retrospective observational studies, prospective descriptive studies, case-control studies and meta-studies were included meta-analyses. It was concluded that symptoms related to olfactory dysfunctions caused by COVID-19 vary according to age, sex, genetics, stage of the disease and pre-existing comorbidities. The mechanism of action by the virus to promote sensory changes is still uncertain. The main evidence suggests viral dissemination through the olfactory cleft neuroepithelium, with consequent infiltration in the olfactory bulb or neural loss mechanism, with direct damage to the olfactory sensory neurons. Given the complexity of the infection caused by COVID-19 it is essential to continue thematic research, especially in relation to the new variants of SARS-CoV-2.El estudio tiene como objetivo recopilar y sintetizar información científica relacionada con las disfunciones olfativas causadas por el SARS-CoV-2 (COVID-19). Esta es una revisión integrativa de la literatura realizada a partir de revistas científicas publicadas de agosto a diciembre de 2021. Se incluyeron artículos originales con revisiones sistemáticas de la literatura, estudios observacionales retrospectivos, estudios descriptivos prospectivos, estudios de casos y controles y metaestudios. Se concluyó que los síntomas relacionados con las disfunciones olfatorias provocadas por el COVID-19 varían según la edad, el sexo, la genética, el estadio de la enfermedad y las comorbilidades preexistentes. El mecanismo de acción del virus para promover cambios sensoriales aún es incierto. La principal evidencia sugiere diseminación viral a través del neuroepitelio de la hendidura olfatoria, con la consiguiente infiltración en el bulbo olfatorio o mecanismo de pérdida neural, con daño directo a las neuronas sensoriales olfatorias. Dada la complejidad de la infección por COVID-19 es fundamental continuar con la investigación temática, especialmente en relación con las nuevas variantes del SARS-CoV-2.O estudo visa reunir e sintetizar informações científicas relacionadas às disfunções olfatórias provocadas pelo SARS-CoV-2 (COVID-19). Trata-se de uma revisão integrativa da literatura realizada a partir de periódicos científicos publicados no período de agosto a dezembro de 2021. Foram incluídos artigos originais com revisões bibliográficas sistemáticas, estudos retrospectivos observacionais, estudos descritivos prospectivos, estudos caso-controle e estudos de meta-análises. Concluiu-se que os sintomas relacionados às disfunções olfatórias causadas pela COVID-19 oscilam de acordo com a idade, sexo, genética, estágio da doença e comorbidades pré-existentes. Ainda é incerto o mecanismo de atuação pelo vírus para promover alterações sensoriais. As principais evidências sugerem disseminação viral através do neuroepitélio da fenda olfatória, com consequente infiltração no bulbo olfatório ou mecanismo de perda neural, com a lesão direta dos neurônios sensoriais olfativos. Dada a complexidade da infecção causada pela COVID-19 torna-se primordial a continuidade de pesquisas temáticas, principalmente, em relação às novas variantes do SARS-CoV-2.Research, Society and Development2022-04-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2838410.33448/rsd-v11i5.28384Research, Society and Development; Vol. 11 No. 5; e45911528384Research, Society and Development; Vol. 11 Núm. 5; e45911528384Research, Society and Development; v. 11 n. 5; e459115283842525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/28384/24746Copyright (c) 2022 Daniela Vieira Buchaim; Laura Badiz Furlaneto; Maria Eduarda Guelfi Pinto; Natália Lopes Silva; Tarek Mustafa Oliveira; Otávio Simões Girotto; Yuuki Daniel Tahara Vilas Boas; Gabrielle Gomides Marconato; João Victor Pereira Rocha; Lucas Ryuiti Adatihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBuchaim, Daniela VieiraFurlaneto, Laura BadizPinto, Maria Eduarda GuelfiSilva, Natália LopesOliveira, Tarek MustafaGirotto, Otávio SimõesBoas, Yuuki Daniel Tahara VilasMarconato, Gabrielle GomidesRocha, João Victor PereiraAdati, Lucas Ryuiti2022-04-17T18:18:56Zoai:ojs.pkp.sfu.ca:article/28384Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:45:48.744092Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Integrative review on olfactory disfunctions caused by COVID-19 Revisión integrativa sobre las disfunciones olfativas por COVID-19 Revisão integrativa sobre disfunções olfatórias causadas pela COVID-19 |
| title |
Integrative review on olfactory disfunctions caused by COVID-19 |
| spellingShingle |
Integrative review on olfactory disfunctions caused by COVID-19 Buchaim, Daniela Vieira SARS-CoV-2 Severe acute respiratory syndrome Olfactory dysfunction Hypogeusia Teaching. SARS-CoV-2 Síndrome respiratorio agudo severo Disfunción olfativa Hipogeusia Enseñanza. SARS-CoV-2 Síndrome respiratória aguda grave Disfunção olfativa Hipogeusia Ensino. |
| title_short |
Integrative review on olfactory disfunctions caused by COVID-19 |
| title_full |
Integrative review on olfactory disfunctions caused by COVID-19 |
| title_fullStr |
Integrative review on olfactory disfunctions caused by COVID-19 |
| title_full_unstemmed |
Integrative review on olfactory disfunctions caused by COVID-19 |
| title_sort |
Integrative review on olfactory disfunctions caused by COVID-19 |
| author |
Buchaim, Daniela Vieira |
| author_facet |
Buchaim, Daniela Vieira Furlaneto, Laura Badiz Pinto, Maria Eduarda Guelfi Silva, Natália Lopes Oliveira, Tarek Mustafa Girotto, Otávio Simões Boas, Yuuki Daniel Tahara Vilas Marconato, Gabrielle Gomides Rocha, João Victor Pereira Adati, Lucas Ryuiti |
| author_role |
author |
| author2 |
Furlaneto, Laura Badiz Pinto, Maria Eduarda Guelfi Silva, Natália Lopes Oliveira, Tarek Mustafa Girotto, Otávio Simões Boas, Yuuki Daniel Tahara Vilas Marconato, Gabrielle Gomides Rocha, João Victor Pereira Adati, Lucas Ryuiti |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Buchaim, Daniela Vieira Furlaneto, Laura Badiz Pinto, Maria Eduarda Guelfi Silva, Natália Lopes Oliveira, Tarek Mustafa Girotto, Otávio Simões Boas, Yuuki Daniel Tahara Vilas Marconato, Gabrielle Gomides Rocha, João Victor Pereira Adati, Lucas Ryuiti |
| dc.subject.por.fl_str_mv |
SARS-CoV-2 Severe acute respiratory syndrome Olfactory dysfunction Hypogeusia Teaching. SARS-CoV-2 Síndrome respiratorio agudo severo Disfunción olfativa Hipogeusia Enseñanza. SARS-CoV-2 Síndrome respiratória aguda grave Disfunção olfativa Hipogeusia Ensino. |
| topic |
SARS-CoV-2 Severe acute respiratory syndrome Olfactory dysfunction Hypogeusia Teaching. SARS-CoV-2 Síndrome respiratorio agudo severo Disfunción olfativa Hipogeusia Enseñanza. SARS-CoV-2 Síndrome respiratória aguda grave Disfunção olfativa Hipogeusia Ensino. |
| description |
The study aims to gather and synthesize scientific information related to olfactory dysfunctions caused by SARS-CoV-2 (COVID-19). This is an integrative literature review carried out from scientific journals published from August to December 2021. Original articles with systematic literature reviews, retrospective observational studies, prospective descriptive studies, case-control studies and meta-studies were included meta-analyses. It was concluded that symptoms related to olfactory dysfunctions caused by COVID-19 vary according to age, sex, genetics, stage of the disease and pre-existing comorbidities. The mechanism of action by the virus to promote sensory changes is still uncertain. The main evidence suggests viral dissemination through the olfactory cleft neuroepithelium, with consequent infiltration in the olfactory bulb or neural loss mechanism, with direct damage to the olfactory sensory neurons. Given the complexity of the infection caused by COVID-19 it is essential to continue thematic research, especially in relation to the new variants of SARS-CoV-2. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-04-12 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/28384 10.33448/rsd-v11i5.28384 |
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https://rsdjournal.org/index.php/rsd/article/view/28384 |
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10.33448/rsd-v11i5.28384 |
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por |
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por |
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https://rsdjournal.org/index.php/rsd/article/view/28384/24746 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 11 No. 5; e45911528384 Research, Society and Development; Vol. 11 Núm. 5; e45911528384 Research, Society and Development; v. 11 n. 5; e45911528384 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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