ESBL producing enterobacteria isolated from outpatients urocultures

Detalhes bibliográficos
Autor(a) principal: Souza, Geziella Aurea Aparecida Damasceno
Data de Publicação: 2021
Outros Autores: Prince, Karina Andrade de, Xavier, Lorena Aguilar, Oliveira, Denise Cardoso, Alves, Daniella Mendes, Paula, Flávia Mendes Tourinho de, Cardoso, Juliana Beatriz Lima, Costa, Marina Ramos, Garcia, Lúcia Maria, Santo, Luçandra Ramos Espirito
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/15701
Resumo: The resistance mechanism due to the production of broad-spectrum beta-lactamases (ESBL) has been increasingly common in public health, both in hospital and in community. The objective of this study was to analyze the cases of ESBL in enterobacteria isolated from outpatients urine cultures. This is a quantitative, descriptive cross-sectional study, retrospective documentary type. Data were collected from the uroculture records of community patients treated at a private laboratory of Analysis, located in Montes Claros, Minas Gerais, from October 2016 to September 2017. There were 6,248 uroculture reports analyzed, wich 15.7% (n=984) were positive. Among the positive ones, 79.4% (n=781) were enterobacteria and 4.5% of these (n=35) are producing ESBL. Among ESBL producers, the most prevalent species were Escherichia coli (68.6%/n=24), and Klebsiella pneumoniae 25.7%/n=9). Analyzing ESBL antimicrobial resistance profile, it appears that 100% are resistant to all cephalosporins. There was also a significant percentage of strains resistant to antibiotics with beta-lactamases inhibitors (31.4%), quinolones (71.4%) and sulfamethoxazole/timetoprime (71.4%). The Klebsiella pneumoniae isolates showed a significant relationship with 3.76 greater chance (p <0.0008) of being ESBL producers. This study shows bacterial resistance regarding the production of ESBL presents in community pathogens, outside the hospital environment.
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spelling ESBL producing enterobacteria isolated from outpatients uroculturesEnterobacterias productoras de BLEE aisladas de urocultivos de pacientes ambulatorios Enterobactérias produtoras de ESBL isoladas de uroculturas de pacientes ambulatoriais Beta-LactamasasInfecciones UrinariasInfecciones Comunitarias AdquiridasResistencia a Múltiples MedicamentosKlebsiella pneumoniae.BetalactamasesInfecções UrináriasInfecções Comunitárias AdquiridasResistência a Múltiplos MedicamentosKlebsiella pneumoniae.Beta-LactamasesUrinary Tract InfectionsCommunity-Acquired InfectionsMultidrug ResistanceKlebsiella pneumoniae.The resistance mechanism due to the production of broad-spectrum beta-lactamases (ESBL) has been increasingly common in public health, both in hospital and in community. The objective of this study was to analyze the cases of ESBL in enterobacteria isolated from outpatients urine cultures. This is a quantitative, descriptive cross-sectional study, retrospective documentary type. Data were collected from the uroculture records of community patients treated at a private laboratory of Analysis, located in Montes Claros, Minas Gerais, from October 2016 to September 2017. There were 6,248 uroculture reports analyzed, wich 15.7% (n=984) were positive. Among the positive ones, 79.4% (n=781) were enterobacteria and 4.5% of these (n=35) are producing ESBL. Among ESBL producers, the most prevalent species were Escherichia coli (68.6%/n=24), and Klebsiella pneumoniae 25.7%/n=9). Analyzing ESBL antimicrobial resistance profile, it appears that 100% are resistant to all cephalosporins. There was also a significant percentage of strains resistant to antibiotics with beta-lactamases inhibitors (31.4%), quinolones (71.4%) and sulfamethoxazole/timetoprime (71.4%). The Klebsiella pneumoniae isolates showed a significant relationship with 3.76 greater chance (p <0.0008) of being ESBL producers. This study shows bacterial resistance regarding the production of ESBL presents in community pathogens, outside the hospital environment.El mecanismo de resistencia debido a la producción de betalactamasas de amplio espectro (BLEE) ha sido cada vez más común en la salud pública, tanto en el hospital como en la comunidad. El objetivo de este estudio fue analizar los casos de BLEE en enterobacterias aisladas de urocultivos de pacientes ambulatorios. Se trata de un estudio cuantitativo, descriptivo, transversal, de tipo documental retrospectivo. Los datos fueron recolectados de los registros de urocultivo de pacientes comunitarios atendidos en un laboratorio privado de Análisis, ubicado en Montes Claros, Minas Gerais, desde octubre de 2016 a septiembre de 2017. Se analizaron 6.248 registros de urocultivo, siendo 15.7% (n = 984) positivos. Entre las positivas, el 79,4% (n = 781) eran enterobacterias y el 4,5% de estas (n = 35) productoras de BLEE. Entre los productores de BLEE, las especies más prevalentes fueron Escherichia coli (68,6%/n = 24) y Klebsiella pneumoniae (25,7%/n = 9). Al analizar el perfil de resistencia a los antimicrobianos BLEE, parece que el 100% son resistentes a todas las cefalosporinas. También hubo un porcentaje significativo de cepas resistentes a antibióticos con inhibidores de betalactamasas (31,4%), quinolonas (71,4%) y sulfametoxazol/timetoprime (71,4%). Los aislados de Klebsiella pneumoniae tuvieron una relación significativa con una probabilidad 3.76 mayor (p <0,0008) de ser productores de BLEE. Este estudio muestra la resistencia bacteriana a la producción de BLEE presentes en patógenos comunitarios, fuera del ámbito hospitalario.O mecanismo de resistência por produção de betalactamases de espectro ampliado (ESBL) vem sendo cada vez mais frequente em saúde pública, tanto no ambiente hospitalar como na comunidade. O objetivo deste estudo foi analisar os casos ocorridos de ESBL em enterobactérias isoladas de uroculturas de pacientes ambulatoriais. Trata-se de um estudo quantitativo, descritivo de delineamento transversal, do tipo documental retrospectivo. Os dados foram coletados a partir dos registros de uroculturas de pacientes comunitários atendidos em um Laboratório de Análises da rede privada, localizado em Montes Claros, Minas Gerais, no período de outubro de 2016 a setembro de 2017. Foram analisados 6.248 registros de uroculturas, sendo 15,7% (n=984) positivas. Dentre as positivas, 79,4% (n=781) eram enterobactérias e 4,5% dessas (n=35) produtoras de ESBL. Entre os produtores de ESBL, as espécies mais prevalentes foram Escherichia coli (68,6%/n=24), e Klebsiella pneumoniae (25,7%/n=9). Analisando o perfil de resistência aos antimicrobianos dos ESBL, verifica-se que 100% são resistentes a todas as cefalosporinas. Observou-se também um percentual significativo de cepas resistentes a antibióticos com inibidores de betalactamases (31,4%), a quinolonas (71,4%) e a sulfametoxazol/timetoprima (71,4%). Os isolados de Klebsiella pneumoniae apresentaram uma relação significativa com 3, 76 maior chance (p<0,0008) de serem produtores de ESBL. Este estudo mostra a resistência bacteriana quanto a produção de ESBL presente em patógenos comunitários, fora do ambiente hospitalar.Research, Society and Development2021-06-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1570110.33448/rsd-v10i6.15701Research, Society and Development; Vol. 10 No. 6; e37410615701Research, Society and Development; Vol. 10 Núm. 6; e37410615701Research, Society and Development; v. 10 n. 6; e374106157012525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/15701/14210Copyright (c) 2021 Geziella Aurea Aparecida Damasceno Souza; Karina Andrade de Prince; Lorena Aguilar Xavier; Denise Cardoso Oliveira; Daniella Mendes Alves; Flávia Mendes Tourinho de Paula; Juliana Beatriz Lima Cardoso; Marina Ramos Costa; Lúcia Maria Garcia; Luçandra Ramos Espirito Santohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSouza, Geziella Aurea Aparecida DamascenoPrince, Karina Andrade deXavier, Lorena AguilarOliveira, Denise CardosoAlves, Daniella MendesPaula, Flávia Mendes Tourinho deCardoso, Juliana Beatriz LimaCosta, Marina RamosGarcia, Lúcia MariaSanto, Luçandra Ramos Espirito2021-06-10T22:51:46Zoai:ojs.pkp.sfu.ca:article/15701Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:28.957972Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv ESBL producing enterobacteria isolated from outpatients urocultures
Enterobacterias productoras de BLEE aisladas de urocultivos de pacientes ambulatorios
Enterobactérias produtoras de ESBL isoladas de uroculturas de pacientes ambulatoriais
title ESBL producing enterobacteria isolated from outpatients urocultures
spellingShingle ESBL producing enterobacteria isolated from outpatients urocultures
Souza, Geziella Aurea Aparecida Damasceno
Beta-Lactamasas
Infecciones Urinarias
Infecciones Comunitarias Adquiridas
Resistencia a Múltiples Medicamentos
Klebsiella pneumoniae.
Betalactamases
Infecções Urinárias
Infecções Comunitárias Adquiridas
Resistência a Múltiplos Medicamentos
Klebsiella pneumoniae.
Beta-Lactamases
Urinary Tract Infections
Community-Acquired Infections
Multidrug Resistance
Klebsiella pneumoniae.
title_short ESBL producing enterobacteria isolated from outpatients urocultures
title_full ESBL producing enterobacteria isolated from outpatients urocultures
title_fullStr ESBL producing enterobacteria isolated from outpatients urocultures
title_full_unstemmed ESBL producing enterobacteria isolated from outpatients urocultures
title_sort ESBL producing enterobacteria isolated from outpatients urocultures
author Souza, Geziella Aurea Aparecida Damasceno
author_facet Souza, Geziella Aurea Aparecida Damasceno
Prince, Karina Andrade de
Xavier, Lorena Aguilar
Oliveira, Denise Cardoso
Alves, Daniella Mendes
Paula, Flávia Mendes Tourinho de
Cardoso, Juliana Beatriz Lima
Costa, Marina Ramos
Garcia, Lúcia Maria
Santo, Luçandra Ramos Espirito
author_role author
author2 Prince, Karina Andrade de
Xavier, Lorena Aguilar
Oliveira, Denise Cardoso
Alves, Daniella Mendes
Paula, Flávia Mendes Tourinho de
Cardoso, Juliana Beatriz Lima
Costa, Marina Ramos
Garcia, Lúcia Maria
Santo, Luçandra Ramos Espirito
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Souza, Geziella Aurea Aparecida Damasceno
Prince, Karina Andrade de
Xavier, Lorena Aguilar
Oliveira, Denise Cardoso
Alves, Daniella Mendes
Paula, Flávia Mendes Tourinho de
Cardoso, Juliana Beatriz Lima
Costa, Marina Ramos
Garcia, Lúcia Maria
Santo, Luçandra Ramos Espirito
dc.subject.por.fl_str_mv Beta-Lactamasas
Infecciones Urinarias
Infecciones Comunitarias Adquiridas
Resistencia a Múltiples Medicamentos
Klebsiella pneumoniae.
Betalactamases
Infecções Urinárias
Infecções Comunitárias Adquiridas
Resistência a Múltiplos Medicamentos
Klebsiella pneumoniae.
Beta-Lactamases
Urinary Tract Infections
Community-Acquired Infections
Multidrug Resistance
Klebsiella pneumoniae.
topic Beta-Lactamasas
Infecciones Urinarias
Infecciones Comunitarias Adquiridas
Resistencia a Múltiples Medicamentos
Klebsiella pneumoniae.
Betalactamases
Infecções Urinárias
Infecções Comunitárias Adquiridas
Resistência a Múltiplos Medicamentos
Klebsiella pneumoniae.
Beta-Lactamases
Urinary Tract Infections
Community-Acquired Infections
Multidrug Resistance
Klebsiella pneumoniae.
description The resistance mechanism due to the production of broad-spectrum beta-lactamases (ESBL) has been increasingly common in public health, both in hospital and in community. The objective of this study was to analyze the cases of ESBL in enterobacteria isolated from outpatients urine cultures. This is a quantitative, descriptive cross-sectional study, retrospective documentary type. Data were collected from the uroculture records of community patients treated at a private laboratory of Analysis, located in Montes Claros, Minas Gerais, from October 2016 to September 2017. There were 6,248 uroculture reports analyzed, wich 15.7% (n=984) were positive. Among the positive ones, 79.4% (n=781) were enterobacteria and 4.5% of these (n=35) are producing ESBL. Among ESBL producers, the most prevalent species were Escherichia coli (68.6%/n=24), and Klebsiella pneumoniae 25.7%/n=9). Analyzing ESBL antimicrobial resistance profile, it appears that 100% are resistant to all cephalosporins. There was also a significant percentage of strains resistant to antibiotics with beta-lactamases inhibitors (31.4%), quinolones (71.4%) and sulfamethoxazole/timetoprime (71.4%). The Klebsiella pneumoniae isolates showed a significant relationship with 3.76 greater chance (p <0.0008) of being ESBL producers. This study shows bacterial resistance regarding the production of ESBL presents in community pathogens, outside the hospital environment.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/15701
10.33448/rsd-v10i6.15701
url https://rsdjournal.org/index.php/rsd/article/view/15701
identifier_str_mv 10.33448/rsd-v10i6.15701
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/15701/14210
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 6; e37410615701
Research, Society and Development; Vol. 10 Núm. 6; e37410615701
Research, Society and Development; v. 10 n. 6; e37410615701
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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