ESBL producing enterobacteria isolated from outpatients urocultures
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/15701 |
Resumo: | The resistance mechanism due to the production of broad-spectrum beta-lactamases (ESBL) has been increasingly common in public health, both in hospital and in community. The objective of this study was to analyze the cases of ESBL in enterobacteria isolated from outpatients urine cultures. This is a quantitative, descriptive cross-sectional study, retrospective documentary type. Data were collected from the uroculture records of community patients treated at a private laboratory of Analysis, located in Montes Claros, Minas Gerais, from October 2016 to September 2017. There were 6,248 uroculture reports analyzed, wich 15.7% (n=984) were positive. Among the positive ones, 79.4% (n=781) were enterobacteria and 4.5% of these (n=35) are producing ESBL. Among ESBL producers, the most prevalent species were Escherichia coli (68.6%/n=24), and Klebsiella pneumoniae 25.7%/n=9). Analyzing ESBL antimicrobial resistance profile, it appears that 100% are resistant to all cephalosporins. There was also a significant percentage of strains resistant to antibiotics with beta-lactamases inhibitors (31.4%), quinolones (71.4%) and sulfamethoxazole/timetoprime (71.4%). The Klebsiella pneumoniae isolates showed a significant relationship with 3.76 greater chance (p <0.0008) of being ESBL producers. This study shows bacterial resistance regarding the production of ESBL presents in community pathogens, outside the hospital environment. |
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ESBL producing enterobacteria isolated from outpatients uroculturesEnterobacterias productoras de BLEE aisladas de urocultivos de pacientes ambulatorios Enterobactérias produtoras de ESBL isoladas de uroculturas de pacientes ambulatoriais Beta-LactamasasInfecciones UrinariasInfecciones Comunitarias AdquiridasResistencia a Múltiples MedicamentosKlebsiella pneumoniae.BetalactamasesInfecções UrináriasInfecções Comunitárias AdquiridasResistência a Múltiplos MedicamentosKlebsiella pneumoniae.Beta-LactamasesUrinary Tract InfectionsCommunity-Acquired InfectionsMultidrug ResistanceKlebsiella pneumoniae.The resistance mechanism due to the production of broad-spectrum beta-lactamases (ESBL) has been increasingly common in public health, both in hospital and in community. The objective of this study was to analyze the cases of ESBL in enterobacteria isolated from outpatients urine cultures. This is a quantitative, descriptive cross-sectional study, retrospective documentary type. Data were collected from the uroculture records of community patients treated at a private laboratory of Analysis, located in Montes Claros, Minas Gerais, from October 2016 to September 2017. There were 6,248 uroculture reports analyzed, wich 15.7% (n=984) were positive. Among the positive ones, 79.4% (n=781) were enterobacteria and 4.5% of these (n=35) are producing ESBL. Among ESBL producers, the most prevalent species were Escherichia coli (68.6%/n=24), and Klebsiella pneumoniae 25.7%/n=9). Analyzing ESBL antimicrobial resistance profile, it appears that 100% are resistant to all cephalosporins. There was also a significant percentage of strains resistant to antibiotics with beta-lactamases inhibitors (31.4%), quinolones (71.4%) and sulfamethoxazole/timetoprime (71.4%). The Klebsiella pneumoniae isolates showed a significant relationship with 3.76 greater chance (p <0.0008) of being ESBL producers. This study shows bacterial resistance regarding the production of ESBL presents in community pathogens, outside the hospital environment.El mecanismo de resistencia debido a la producción de betalactamasas de amplio espectro (BLEE) ha sido cada vez más común en la salud pública, tanto en el hospital como en la comunidad. El objetivo de este estudio fue analizar los casos de BLEE en enterobacterias aisladas de urocultivos de pacientes ambulatorios. Se trata de un estudio cuantitativo, descriptivo, transversal, de tipo documental retrospectivo. Los datos fueron recolectados de los registros de urocultivo de pacientes comunitarios atendidos en un laboratorio privado de Análisis, ubicado en Montes Claros, Minas Gerais, desde octubre de 2016 a septiembre de 2017. Se analizaron 6.248 registros de urocultivo, siendo 15.7% (n = 984) positivos. Entre las positivas, el 79,4% (n = 781) eran enterobacterias y el 4,5% de estas (n = 35) productoras de BLEE. Entre los productores de BLEE, las especies más prevalentes fueron Escherichia coli (68,6%/n = 24) y Klebsiella pneumoniae (25,7%/n = 9). Al analizar el perfil de resistencia a los antimicrobianos BLEE, parece que el 100% son resistentes a todas las cefalosporinas. También hubo un porcentaje significativo de cepas resistentes a antibióticos con inhibidores de betalactamasas (31,4%), quinolonas (71,4%) y sulfametoxazol/timetoprime (71,4%). Los aislados de Klebsiella pneumoniae tuvieron una relación significativa con una probabilidad 3.76 mayor (p <0,0008) de ser productores de BLEE. Este estudio muestra la resistencia bacteriana a la producción de BLEE presentes en patógenos comunitarios, fuera del ámbito hospitalario.O mecanismo de resistência por produção de betalactamases de espectro ampliado (ESBL) vem sendo cada vez mais frequente em saúde pública, tanto no ambiente hospitalar como na comunidade. O objetivo deste estudo foi analisar os casos ocorridos de ESBL em enterobactérias isoladas de uroculturas de pacientes ambulatoriais. Trata-se de um estudo quantitativo, descritivo de delineamento transversal, do tipo documental retrospectivo. Os dados foram coletados a partir dos registros de uroculturas de pacientes comunitários atendidos em um Laboratório de Análises da rede privada, localizado em Montes Claros, Minas Gerais, no período de outubro de 2016 a setembro de 2017. Foram analisados 6.248 registros de uroculturas, sendo 15,7% (n=984) positivas. Dentre as positivas, 79,4% (n=781) eram enterobactérias e 4,5% dessas (n=35) produtoras de ESBL. Entre os produtores de ESBL, as espécies mais prevalentes foram Escherichia coli (68,6%/n=24), e Klebsiella pneumoniae (25,7%/n=9). Analisando o perfil de resistência aos antimicrobianos dos ESBL, verifica-se que 100% são resistentes a todas as cefalosporinas. Observou-se também um percentual significativo de cepas resistentes a antibióticos com inibidores de betalactamases (31,4%), a quinolonas (71,4%) e a sulfametoxazol/timetoprima (71,4%). Os isolados de Klebsiella pneumoniae apresentaram uma relação significativa com 3, 76 maior chance (p<0,0008) de serem produtores de ESBL. Este estudo mostra a resistência bacteriana quanto a produção de ESBL presente em patógenos comunitários, fora do ambiente hospitalar.Research, Society and Development2021-06-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1570110.33448/rsd-v10i6.15701Research, Society and Development; Vol. 10 No. 6; e37410615701Research, Society and Development; Vol. 10 Núm. 6; e37410615701Research, Society and Development; v. 10 n. 6; e374106157012525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/15701/14210Copyright (c) 2021 Geziella Aurea Aparecida Damasceno Souza; Karina Andrade de Prince; Lorena Aguilar Xavier; Denise Cardoso Oliveira; Daniella Mendes Alves; Flávia Mendes Tourinho de Paula; Juliana Beatriz Lima Cardoso; Marina Ramos Costa; Lúcia Maria Garcia; Luçandra Ramos Espirito Santohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSouza, Geziella Aurea Aparecida DamascenoPrince, Karina Andrade deXavier, Lorena AguilarOliveira, Denise CardosoAlves, Daniella MendesPaula, Flávia Mendes Tourinho deCardoso, Juliana Beatriz LimaCosta, Marina RamosGarcia, Lúcia MariaSanto, Luçandra Ramos Espirito2021-06-10T22:51:46Zoai:ojs.pkp.sfu.ca:article/15701Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:28.957972Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
ESBL producing enterobacteria isolated from outpatients urocultures Enterobacterias productoras de BLEE aisladas de urocultivos de pacientes ambulatorios Enterobactérias produtoras de ESBL isoladas de uroculturas de pacientes ambulatoriais |
title |
ESBL producing enterobacteria isolated from outpatients urocultures |
spellingShingle |
ESBL producing enterobacteria isolated from outpatients urocultures Souza, Geziella Aurea Aparecida Damasceno Beta-Lactamasas Infecciones Urinarias Infecciones Comunitarias Adquiridas Resistencia a Múltiples Medicamentos Klebsiella pneumoniae. Betalactamases Infecções Urinárias Infecções Comunitárias Adquiridas Resistência a Múltiplos Medicamentos Klebsiella pneumoniae. Beta-Lactamases Urinary Tract Infections Community-Acquired Infections Multidrug Resistance Klebsiella pneumoniae. |
title_short |
ESBL producing enterobacteria isolated from outpatients urocultures |
title_full |
ESBL producing enterobacteria isolated from outpatients urocultures |
title_fullStr |
ESBL producing enterobacteria isolated from outpatients urocultures |
title_full_unstemmed |
ESBL producing enterobacteria isolated from outpatients urocultures |
title_sort |
ESBL producing enterobacteria isolated from outpatients urocultures |
author |
Souza, Geziella Aurea Aparecida Damasceno |
author_facet |
Souza, Geziella Aurea Aparecida Damasceno Prince, Karina Andrade de Xavier, Lorena Aguilar Oliveira, Denise Cardoso Alves, Daniella Mendes Paula, Flávia Mendes Tourinho de Cardoso, Juliana Beatriz Lima Costa, Marina Ramos Garcia, Lúcia Maria Santo, Luçandra Ramos Espirito |
author_role |
author |
author2 |
Prince, Karina Andrade de Xavier, Lorena Aguilar Oliveira, Denise Cardoso Alves, Daniella Mendes Paula, Flávia Mendes Tourinho de Cardoso, Juliana Beatriz Lima Costa, Marina Ramos Garcia, Lúcia Maria Santo, Luçandra Ramos Espirito |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Souza, Geziella Aurea Aparecida Damasceno Prince, Karina Andrade de Xavier, Lorena Aguilar Oliveira, Denise Cardoso Alves, Daniella Mendes Paula, Flávia Mendes Tourinho de Cardoso, Juliana Beatriz Lima Costa, Marina Ramos Garcia, Lúcia Maria Santo, Luçandra Ramos Espirito |
dc.subject.por.fl_str_mv |
Beta-Lactamasas Infecciones Urinarias Infecciones Comunitarias Adquiridas Resistencia a Múltiples Medicamentos Klebsiella pneumoniae. Betalactamases Infecções Urinárias Infecções Comunitárias Adquiridas Resistência a Múltiplos Medicamentos Klebsiella pneumoniae. Beta-Lactamases Urinary Tract Infections Community-Acquired Infections Multidrug Resistance Klebsiella pneumoniae. |
topic |
Beta-Lactamasas Infecciones Urinarias Infecciones Comunitarias Adquiridas Resistencia a Múltiples Medicamentos Klebsiella pneumoniae. Betalactamases Infecções Urinárias Infecções Comunitárias Adquiridas Resistência a Múltiplos Medicamentos Klebsiella pneumoniae. Beta-Lactamases Urinary Tract Infections Community-Acquired Infections Multidrug Resistance Klebsiella pneumoniae. |
description |
The resistance mechanism due to the production of broad-spectrum beta-lactamases (ESBL) has been increasingly common in public health, both in hospital and in community. The objective of this study was to analyze the cases of ESBL in enterobacteria isolated from outpatients urine cultures. This is a quantitative, descriptive cross-sectional study, retrospective documentary type. Data were collected from the uroculture records of community patients treated at a private laboratory of Analysis, located in Montes Claros, Minas Gerais, from October 2016 to September 2017. There were 6,248 uroculture reports analyzed, wich 15.7% (n=984) were positive. Among the positive ones, 79.4% (n=781) were enterobacteria and 4.5% of these (n=35) are producing ESBL. Among ESBL producers, the most prevalent species were Escherichia coli (68.6%/n=24), and Klebsiella pneumoniae 25.7%/n=9). Analyzing ESBL antimicrobial resistance profile, it appears that 100% are resistant to all cephalosporins. There was also a significant percentage of strains resistant to antibiotics with beta-lactamases inhibitors (31.4%), quinolones (71.4%) and sulfamethoxazole/timetoprime (71.4%). The Klebsiella pneumoniae isolates showed a significant relationship with 3.76 greater chance (p <0.0008) of being ESBL producers. This study shows bacterial resistance regarding the production of ESBL presents in community pathogens, outside the hospital environment. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/15701 10.33448/rsd-v10i6.15701 |
url |
https://rsdjournal.org/index.php/rsd/article/view/15701 |
identifier_str_mv |
10.33448/rsd-v10i6.15701 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/15701/14210 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 6; e37410615701 Research, Society and Development; Vol. 10 Núm. 6; e37410615701 Research, Society and Development; v. 10 n. 6; e37410615701 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052641214201856 |