Parkinson's disease secondary to COVID-19: a systematic review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/24397 |
Resumo: | Objective: This study aimed to carry out a systematic review of Parkinson's Disease and its relationship with COVID-19. Methods: We used and adapted the criteria present in PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and aimed to identify peer-reviewed publications on the topic of Parkinson's disease related to COVID-19. Results: Parkinson's disease after COVID-19 is present in some cases and seems to be related to mechanisms of hyperinflammation mediated by Sars-Cov-2, especially in patients under 60 years of age. Conclusion: The occurrence of Parkinson's disease after an infection with the new coronavirus seems to be explained by the cytolytic effects of the virus, accumulation of intracellular proteins, epigenetic modifications and interactions in inflammatory pathways that cause neuronal death. COVID-19 is also associated with worsening of the symptoms in people with previously diagnosed Parkinson's Disease. |
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Parkinson's disease secondary to COVID-19: a systematic reviewEnfermedad de Parkinson secundaria a COVID-19: una revisión sistemáticaDoença de Parkinson secundária a COVID-19: uma revisão sistemáticaDoença de ParkinsonInfecções por CoronavirusNeurologia.Enfermedad de ParkinsonInfecciones por coronavirusNeurología.Parkinson's DiseaseCoronavirus InfectionsNeurology.Objective: This study aimed to carry out a systematic review of Parkinson's Disease and its relationship with COVID-19. Methods: We used and adapted the criteria present in PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and aimed to identify peer-reviewed publications on the topic of Parkinson's disease related to COVID-19. Results: Parkinson's disease after COVID-19 is present in some cases and seems to be related to mechanisms of hyperinflammation mediated by Sars-Cov-2, especially in patients under 60 years of age. Conclusion: The occurrence of Parkinson's disease after an infection with the new coronavirus seems to be explained by the cytolytic effects of the virus, accumulation of intracellular proteins, epigenetic modifications and interactions in inflammatory pathways that cause neuronal death. COVID-19 is also associated with worsening of the symptoms in people with previously diagnosed Parkinson's Disease.Objetivo: Este estudio tuvo como objetivo realizar una revisión sistemática de la Enfermedad de Parkinson y su relación con COVID-19. Métodos: Utilizamos y adaptamos los criterios presentes en PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) y buscamos identificar publicaciones revisadas por pares sobre el tema de la enfermedad de Parkinson relacionada con COVID-19. Resultados: La enfermedad de Parkinson posterior al COVID-19 está presente en algunos casos y parece estar relacionada con mecanismos de hiperinflamación mediados por Sars-Cov-2, especialmente en pacientes menores de 60 años. Conclusión: La aparición de la enfermedad de Parkinson tras una infección por el nuevo coronavirus parece explicarse por los efectos citolíticos del virus, acumulación de proteínas intracelulares, modificaciones epigenéticas e interacciones en vías inflamatorias que provocan muerte neuronal. COVID-19 también se asocia con el empeoramiento de los síntomas de la enfermedad de Parkinson diagnosticada previamente.Objetivo: O presente trabalho teve como objetivo realizar uma revisão sistemática a respeito da Doença de Parkinson e sua relação com a COVID-19. Métodos: Utilizamos e adaptamos os critérios presentes no PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) e objetivou a identificação de publicações revisadas por pares pertencentes a temática da doença de Parkinson relacionada à COVID-19. Resultados: A doença de Parkinson após a COVID-19 está presente em alguns casos e parece estar relacionada com mecanismos de hiperinflamação mediada pelo Sars-Cov-2, principalmente em pacientes abaixo dos 60 anos. Conclusão: A ocorrência da doença de Parkinson após uma infecção pelo novo coronavírus parece ser explicada pelos efeitos citolíticos do vírus, acúmulo de proteínas intracelulares, modificações epigenéticas e interações em vias inflamatórias que causam morte neuronal. A COVID-19 também está associada à piora dos sintomas da Doença de Parkinson previamente diagnosticada.Research, Society and Development2022-01-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2439710.33448/rsd-v11i1.24397Research, Society and Development; Vol. 11 No. 1; e50711124397Research, Society and Development; Vol. 11 Núm. 1; e50711124397Research, Society and Development; v. 11 n. 1; e507111243972525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/24397/22119Copyright (c) 2022 Moises Hamoy; Gabriel Hans Reis Braga; Jones Vinicius Santana Chaves; Ana Carolina Serrão Maia; Diego Arthur Castro Cabral; Fernanda Myllena Sousa Campos; João Paulo do Vale Medeiros; Leonardo Giovanni Castro Cabral; Bruno Patricio dos Santos Oliveira; Joyce Pantoja Braga; Vanessa Jóia de Mello; Eric Homero Albuquerque Paschoalhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessHamoy, MoisesBraga, Gabriel Hans ReisChaves, Jones Vinicius Santana Maia, Ana Carolina Serrão Cabral, Diego Arthur CastroCampos, Fernanda Myllena Sousa Medeiros, João Paulo do Vale Cabral, Leonardo Giovanni Castro Oliveira, Bruno Patricio dos Santos Braga, Joyce Pantoja de Mello, Vanessa JóiaPaschoal, Eric Homero Albuquerque 2022-01-16T18:08:18Zoai:ojs.pkp.sfu.ca:article/24397Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:58.162351Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Parkinson's disease secondary to COVID-19: a systematic review Enfermedad de Parkinson secundaria a COVID-19: una revisión sistemática Doença de Parkinson secundária a COVID-19: uma revisão sistemática |
| title |
Parkinson's disease secondary to COVID-19: a systematic review |
| spellingShingle |
Parkinson's disease secondary to COVID-19: a systematic review Hamoy, Moises Doença de Parkinson Infecções por Coronavirus Neurologia. Enfermedad de Parkinson Infecciones por coronavirus Neurología. Parkinson's Disease Coronavirus Infections Neurology. |
| title_short |
Parkinson's disease secondary to COVID-19: a systematic review |
| title_full |
Parkinson's disease secondary to COVID-19: a systematic review |
| title_fullStr |
Parkinson's disease secondary to COVID-19: a systematic review |
| title_full_unstemmed |
Parkinson's disease secondary to COVID-19: a systematic review |
| title_sort |
Parkinson's disease secondary to COVID-19: a systematic review |
| author |
Hamoy, Moises |
| author_facet |
Hamoy, Moises Braga, Gabriel Hans Reis Chaves, Jones Vinicius Santana Maia, Ana Carolina Serrão Cabral, Diego Arthur Castro Campos, Fernanda Myllena Sousa Medeiros, João Paulo do Vale Cabral, Leonardo Giovanni Castro Oliveira, Bruno Patricio dos Santos Braga, Joyce Pantoja de Mello, Vanessa Jóia Paschoal, Eric Homero Albuquerque |
| author_role |
author |
| author2 |
Braga, Gabriel Hans Reis Chaves, Jones Vinicius Santana Maia, Ana Carolina Serrão Cabral, Diego Arthur Castro Campos, Fernanda Myllena Sousa Medeiros, João Paulo do Vale Cabral, Leonardo Giovanni Castro Oliveira, Bruno Patricio dos Santos Braga, Joyce Pantoja de Mello, Vanessa Jóia Paschoal, Eric Homero Albuquerque |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Hamoy, Moises Braga, Gabriel Hans Reis Chaves, Jones Vinicius Santana Maia, Ana Carolina Serrão Cabral, Diego Arthur Castro Campos, Fernanda Myllena Sousa Medeiros, João Paulo do Vale Cabral, Leonardo Giovanni Castro Oliveira, Bruno Patricio dos Santos Braga, Joyce Pantoja de Mello, Vanessa Jóia Paschoal, Eric Homero Albuquerque |
| dc.subject.por.fl_str_mv |
Doença de Parkinson Infecções por Coronavirus Neurologia. Enfermedad de Parkinson Infecciones por coronavirus Neurología. Parkinson's Disease Coronavirus Infections Neurology. |
| topic |
Doença de Parkinson Infecções por Coronavirus Neurologia. Enfermedad de Parkinson Infecciones por coronavirus Neurología. Parkinson's Disease Coronavirus Infections Neurology. |
| description |
Objective: This study aimed to carry out a systematic review of Parkinson's Disease and its relationship with COVID-19. Methods: We used and adapted the criteria present in PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and aimed to identify peer-reviewed publications on the topic of Parkinson's disease related to COVID-19. Results: Parkinson's disease after COVID-19 is present in some cases and seems to be related to mechanisms of hyperinflammation mediated by Sars-Cov-2, especially in patients under 60 years of age. Conclusion: The occurrence of Parkinson's disease after an infection with the new coronavirus seems to be explained by the cytolytic effects of the virus, accumulation of intracellular proteins, epigenetic modifications and interactions in inflammatory pathways that cause neuronal death. COVID-19 is also associated with worsening of the symptoms in people with previously diagnosed Parkinson's Disease. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-01-13 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/24397 10.33448/rsd-v11i1.24397 |
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https://rsdjournal.org/index.php/rsd/article/view/24397 |
| identifier_str_mv |
10.33448/rsd-v11i1.24397 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/24397/22119 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 11 No. 1; e50711124397 Research, Society and Development; Vol. 11 Núm. 1; e50711124397 Research, Society and Development; v. 11 n. 1; e50711124397 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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