Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/3732 |
Resumo: | Objective: This study aimed to investigate in the literature the effects of vitamin A supplementation or not in patients with cystic fibrosis (CF). Methodology: This is an integrative review carried out by searching for original articles, published in English, Portuguese and Spanish, indexed in the Scielo and Pubmed databases. Results: Of the 8 studies included in the review, 25% (n=2) identified an association between elevated serum retinol levels and improvement of the fibrocystic condition, and 50% (n=4) found positive effects on lung function and clinical conditions, from vitamin A supplementation. In contrast, 25% (n=2) did not observe any correlation between vitamin A use, although they identified an improvement in their status resulting from the intervention. Conclusion: Most studies have shown that the supplemented or not use of vitamin A proved to be potentially beneficial for the clinical and nutritional profile, as well as for the survival of patients with cystic fibrosis. However, there is a need for more research, especially in humans, that address the theme. |
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Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented useVitamina A en la Fibrosis Quística: Efectos de su uso suplementado y no suplementadoVitamina A na Fibrose Cística: Efeitos do seu uso suplementado e não suplementadoCystic FibrosisTherapeuticsAntioxidantNutritional supplementation.Fibrose CísticaTerapêuticaAntioxidanteSuplementação nutricional.Fibrosis quísticaTerapéuticaAntioxidanteSuplementación nutricional.Objective: This study aimed to investigate in the literature the effects of vitamin A supplementation or not in patients with cystic fibrosis (CF). Methodology: This is an integrative review carried out by searching for original articles, published in English, Portuguese and Spanish, indexed in the Scielo and Pubmed databases. Results: Of the 8 studies included in the review, 25% (n=2) identified an association between elevated serum retinol levels and improvement of the fibrocystic condition, and 50% (n=4) found positive effects on lung function and clinical conditions, from vitamin A supplementation. In contrast, 25% (n=2) did not observe any correlation between vitamin A use, although they identified an improvement in their status resulting from the intervention. Conclusion: Most studies have shown that the supplemented or not use of vitamin A proved to be potentially beneficial for the clinical and nutritional profile, as well as for the survival of patients with cystic fibrosis. However, there is a need for more research, especially in humans, that address the theme.Objetivo: Este estudio tuvo como objetivo investigar en la literatura los efectos de la suplementación con vitamina A o no en pacientes con fibrosis quística (FQ). Metodología: Esta es una revisión integradora realizada mediante la búsqueda de artículos originales, publicados en inglés, portugués y español, indexados en las bases de datos Scielo y Pubmed. Resultados: De los 8 estudios incluidos en la revisión, el 25% (n=2) identificó una asociación entre los altos niveles de retinol sérico y la mejora de la condición fibroquística, y el 50% (n=4) encontró efectos positivos sobre la función pulmonar y las condiciones clínicas, de la suplementación con vitamina A. En contraste, el 25% (n=2) no observó ninguna correlación entre el uso de vitamina A, aunque identificaron una mejora en su estado como resultado de la intervención. Conclusión: la mayoría de los estudios han demostrado que el uso suplementado o no de vitamina A demostró ser potencialmente beneficioso para el perfil clínico y nutricional, así como para la supervivencia de pacientes con fibrosis quística. Sin embargo, existe la necesidad de más investigación, especialmente en humanos, que aborde el tema.Objetivo: Esse estudo objetivou investigar na literatura os efeitos do uso suplementado ou não de vitamina A em pacientes com fibrose cística. Metodologia: Trata-se de uma revisão integrativa realizada por meio de pesquisa de artigos originais, publicados em inglês, português e espanhol, indexados nas bases de dados Scielo e Pubmed. Resultados: Dos 8 estudos incluídos na revisão, 25% (n=2) identificaram associação entre níveis elevados de retinol sérico e melhora do quadro fibrocístico, e 50% (n=4) constataram efeitos positivos sobre a função pulmonar e condições clínicas, a partir da suplementação de vitamina A. Em contrapartida, 25% (n=2) não observaram correlações entre uso de vitamina A, embora tenham identificado melhora no seu status oriunda da intervenção. Conclusão: A maioria dos estudos evidenciou que o uso suplementado ou não de vitamina A mostrou-se potencialmente benéfico para o perfil clínico e nutricional, como também para a sobrevida de pacientes com fibrose cística. No entanto, ressalta-se a necessidade de mais pesquisas, especialmente em humanos, que abordem a temática.Research, Society and Development2020-04-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/373210.33448/rsd-v9i7.3732Research, Society and Development; Vol. 9 No. 7; e30973732Research, Society and Development; Vol. 9 Núm. 7; e30973732Research, Society and Development; v. 9 n. 7; e309737322525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/3732/3209Copyright (c) 2020 Thaís Rodrigues Nogueirainfo:eu-repo/semantics/openAccessMachado, Mariana Gama da CunhaPereira, Patrícia BarbosaSilva, Mávia Caline Lopes daNogueira, Thaís Rodrigues2020-08-20T18:05:03Zoai:ojs.pkp.sfu.ca:article/3732Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:27:50.074037Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use Vitamina A en la Fibrosis Quística: Efectos de su uso suplementado y no suplementado Vitamina A na Fibrose Cística: Efeitos do seu uso suplementado e não suplementado |
title |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use |
spellingShingle |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use Machado, Mariana Gama da Cunha Cystic Fibrosis Therapeutics Antioxidant Nutritional supplementation. Fibrose Cística Terapêutica Antioxidante Suplementação nutricional. Fibrosis quística Terapéutica Antioxidante Suplementación nutricional. |
title_short |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use |
title_full |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use |
title_fullStr |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use |
title_full_unstemmed |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use |
title_sort |
Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use |
author |
Machado, Mariana Gama da Cunha |
author_facet |
Machado, Mariana Gama da Cunha Pereira, Patrícia Barbosa Silva, Mávia Caline Lopes da Nogueira, Thaís Rodrigues |
author_role |
author |
author2 |
Pereira, Patrícia Barbosa Silva, Mávia Caline Lopes da Nogueira, Thaís Rodrigues |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Machado, Mariana Gama da Cunha Pereira, Patrícia Barbosa Silva, Mávia Caline Lopes da Nogueira, Thaís Rodrigues |
dc.subject.por.fl_str_mv |
Cystic Fibrosis Therapeutics Antioxidant Nutritional supplementation. Fibrose Cística Terapêutica Antioxidante Suplementação nutricional. Fibrosis quística Terapéutica Antioxidante Suplementación nutricional. |
topic |
Cystic Fibrosis Therapeutics Antioxidant Nutritional supplementation. Fibrose Cística Terapêutica Antioxidante Suplementação nutricional. Fibrosis quística Terapéutica Antioxidante Suplementación nutricional. |
description |
Objective: This study aimed to investigate in the literature the effects of vitamin A supplementation or not in patients with cystic fibrosis (CF). Methodology: This is an integrative review carried out by searching for original articles, published in English, Portuguese and Spanish, indexed in the Scielo and Pubmed databases. Results: Of the 8 studies included in the review, 25% (n=2) identified an association between elevated serum retinol levels and improvement of the fibrocystic condition, and 50% (n=4) found positive effects on lung function and clinical conditions, from vitamin A supplementation. In contrast, 25% (n=2) did not observe any correlation between vitamin A use, although they identified an improvement in their status resulting from the intervention. Conclusion: Most studies have shown that the supplemented or not use of vitamin A proved to be potentially beneficial for the clinical and nutritional profile, as well as for the survival of patients with cystic fibrosis. However, there is a need for more research, especially in humans, that address the theme. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-04-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/3732 10.33448/rsd-v9i7.3732 |
url |
https://rsdjournal.org/index.php/rsd/article/view/3732 |
identifier_str_mv |
10.33448/rsd-v9i7.3732 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/3732/3209 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Thaís Rodrigues Nogueira info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Thaís Rodrigues Nogueira |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 7; e30973732 Research, Society and Development; Vol. 9 Núm. 7; e30973732 Research, Society and Development; v. 9 n. 7; e30973732 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052648326692864 |