Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use

Detalhes bibliográficos
Autor(a) principal: Machado, Mariana Gama da Cunha
Data de Publicação: 2020
Outros Autores: Pereira, Patrícia Barbosa, Silva, Mávia Caline Lopes da, Nogueira, Thaís Rodrigues
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/3732
Resumo: Objective: This study aimed to investigate in the literature the effects of vitamin A supplementation or not in patients with cystic fibrosis (CF). Methodology: This is an integrative review carried out by searching for original articles, published in English, Portuguese and Spanish, indexed in the Scielo and Pubmed databases. Results: Of the 8 studies included in the review, 25% (n=2) identified an association between elevated serum retinol levels and improvement of the fibrocystic condition, and 50% (n=4) found positive effects on lung function and clinical conditions, from vitamin A supplementation. In contrast, 25% (n=2) did not observe any correlation between vitamin A use, although they identified an improvement in their status resulting from the intervention. Conclusion: Most studies have shown that the supplemented or not use of vitamin A proved to be potentially beneficial for the clinical and nutritional profile, as well as for the survival of patients with cystic fibrosis. However, there is a need for more research, especially in humans, that address the theme.
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spelling Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented useVitamina A en la Fibrosis Quística: Efectos de su uso suplementado y no suplementadoVitamina A na Fibrose Cística: Efeitos do seu uso suplementado e não suplementadoCystic FibrosisTherapeuticsAntioxidantNutritional supplementation.Fibrose CísticaTerapêuticaAntioxidanteSuplementação nutricional.Fibrosis quísticaTerapéuticaAntioxidanteSuplementación nutricional.Objective: This study aimed to investigate in the literature the effects of vitamin A supplementation or not in patients with cystic fibrosis (CF). Methodology: This is an integrative review carried out by searching for original articles, published in English, Portuguese and Spanish, indexed in the Scielo and Pubmed databases. Results: Of the 8 studies included in the review, 25% (n=2) identified an association between elevated serum retinol levels and improvement of the fibrocystic condition, and 50% (n=4) found positive effects on lung function and clinical conditions, from vitamin A supplementation. In contrast, 25% (n=2) did not observe any correlation between vitamin A use, although they identified an improvement in their status resulting from the intervention. Conclusion: Most studies have shown that the supplemented or not use of vitamin A proved to be potentially beneficial for the clinical and nutritional profile, as well as for the survival of patients with cystic fibrosis. However, there is a need for more research, especially in humans, that address the theme.Objetivo: Este estudio tuvo como objetivo investigar en la literatura los efectos de la suplementación con vitamina A o no en pacientes con fibrosis quística (FQ). Metodología: Esta es una revisión integradora realizada mediante la búsqueda de artículos originales, publicados en inglés, portugués y español, indexados en las bases de datos Scielo y Pubmed. Resultados: De los 8 estudios incluidos en la revisión, el 25% (n=2) identificó una asociación entre los altos niveles de retinol sérico y la mejora de la condición fibroquística, y el 50% (n=4) encontró efectos positivos sobre la función pulmonar y las condiciones clínicas, de la suplementación con vitamina A. En contraste, el 25% (n=2) no observó ninguna correlación entre el uso de vitamina A, aunque identificaron una mejora en su estado como resultado de la intervención. Conclusión: la mayoría de los estudios han demostrado que el uso suplementado o no de vitamina A demostró ser potencialmente beneficioso para el perfil clínico y nutricional, así como para la supervivencia de pacientes con fibrosis quística. Sin embargo, existe la necesidad de más investigación, especialmente en humanos, que aborde el tema.Objetivo: Esse estudo objetivou investigar na literatura os efeitos do uso suplementado ou não de vitamina A em pacientes com fibrose cística. Metodologia: Trata-se de uma revisão integrativa realizada por meio de pesquisa de artigos originais, publicados em inglês, português e espanhol, indexados nas bases de dados Scielo e Pubmed. Resultados: Dos 8 estudos incluídos na revisão, 25% (n=2) identificaram associação entre níveis elevados de retinol sérico e melhora do quadro fibrocístico, e 50% (n=4) constataram efeitos positivos sobre a função pulmonar e condições clínicas, a partir da suplementação de vitamina A. Em contrapartida, 25% (n=2) não observaram correlações entre uso de vitamina A, embora tenham identificado melhora no seu status oriunda da intervenção. Conclusão: A maioria dos estudos evidenciou que o uso suplementado ou não de vitamina A mostrou-se potencialmente benéfico para o perfil clínico e nutricional, como também para a sobrevida de pacientes com fibrose cística. No entanto, ressalta-se a necessidade de mais pesquisas, especialmente em humanos, que abordem a temática.Research, Society and Development2020-04-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/373210.33448/rsd-v9i7.3732Research, Society and Development; Vol. 9 No. 7; e30973732Research, Society and Development; Vol. 9 Núm. 7; e30973732Research, Society and Development; v. 9 n. 7; e309737322525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/3732/3209Copyright (c) 2020 Thaís Rodrigues Nogueirainfo:eu-repo/semantics/openAccessMachado, Mariana Gama da CunhaPereira, Patrícia BarbosaSilva, Mávia Caline Lopes daNogueira, Thaís Rodrigues2020-08-20T18:05:03Zoai:ojs.pkp.sfu.ca:article/3732Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:27:50.074037Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
Vitamina A en la Fibrosis Quística: Efectos de su uso suplementado y no suplementado
Vitamina A na Fibrose Cística: Efeitos do seu uso suplementado e não suplementado
title Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
spellingShingle Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
Machado, Mariana Gama da Cunha
Cystic Fibrosis
Therapeutics
Antioxidant
Nutritional supplementation.
Fibrose Cística
Terapêutica
Antioxidante
Suplementação nutricional.
Fibrosis quística
Terapéutica
Antioxidante
Suplementación nutricional.
title_short Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
title_full Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
title_fullStr Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
title_full_unstemmed Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
title_sort Vitamin A in Cystic Fibrosis: Effects of its supplemented and non-supplemented use
author Machado, Mariana Gama da Cunha
author_facet Machado, Mariana Gama da Cunha
Pereira, Patrícia Barbosa
Silva, Mávia Caline Lopes da
Nogueira, Thaís Rodrigues
author_role author
author2 Pereira, Patrícia Barbosa
Silva, Mávia Caline Lopes da
Nogueira, Thaís Rodrigues
author2_role author
author
author
dc.contributor.author.fl_str_mv Machado, Mariana Gama da Cunha
Pereira, Patrícia Barbosa
Silva, Mávia Caline Lopes da
Nogueira, Thaís Rodrigues
dc.subject.por.fl_str_mv Cystic Fibrosis
Therapeutics
Antioxidant
Nutritional supplementation.
Fibrose Cística
Terapêutica
Antioxidante
Suplementação nutricional.
Fibrosis quística
Terapéutica
Antioxidante
Suplementación nutricional.
topic Cystic Fibrosis
Therapeutics
Antioxidant
Nutritional supplementation.
Fibrose Cística
Terapêutica
Antioxidante
Suplementação nutricional.
Fibrosis quística
Terapéutica
Antioxidante
Suplementación nutricional.
description Objective: This study aimed to investigate in the literature the effects of vitamin A supplementation or not in patients with cystic fibrosis (CF). Methodology: This is an integrative review carried out by searching for original articles, published in English, Portuguese and Spanish, indexed in the Scielo and Pubmed databases. Results: Of the 8 studies included in the review, 25% (n=2) identified an association between elevated serum retinol levels and improvement of the fibrocystic condition, and 50% (n=4) found positive effects on lung function and clinical conditions, from vitamin A supplementation. In contrast, 25% (n=2) did not observe any correlation between vitamin A use, although they identified an improvement in their status resulting from the intervention. Conclusion: Most studies have shown that the supplemented or not use of vitamin A proved to be potentially beneficial for the clinical and nutritional profile, as well as for the survival of patients with cystic fibrosis. However, there is a need for more research, especially in humans, that address the theme.
publishDate 2020
dc.date.none.fl_str_mv 2020-04-27
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/3732
10.33448/rsd-v9i7.3732
url https://rsdjournal.org/index.php/rsd/article/view/3732
identifier_str_mv 10.33448/rsd-v9i7.3732
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/3732/3209
dc.rights.driver.fl_str_mv Copyright (c) 2020 Thaís Rodrigues Nogueira
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Thaís Rodrigues Nogueira
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 7; e30973732
Research, Society and Development; Vol. 9 Núm. 7; e30973732
Research, Society and Development; v. 9 n. 7; e30973732
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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