Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/9742 |
Resumo: | The main objective of this work was to quantify the phenolic compounds, and to evaluate antioxidant and antimicrobial the activity of Croton cajucara BENTH stem bark extracts. An experimental planning (Box Hunter and Hunter) of two factors and two levels determine which variables influenced in the extraction process was used. To the quantification of phenolic compounds was used the methodology of Folin-Ciocalteau. To the antioxidant activity the IC50 method was applied. For the antimicrobial analysis, the microdilution method was employed to indicate the Minimum Inhibitory Concentration (MIC) against the bacterial strains, as well as fungal strain. In the quantification of phenolic compounds, there was a variation between 26.98 and 50.32 mgEAG /g. Regarding antioxidant activity, values from 9.01% to 14.03% were found. For antimicrobial activity, the extracts did not inhibit the growth of the tested bacteria and fungi. All the results were treated statistically and, in general, proved that the best extraction conditions were T = 60 °C and G = 0.10 mm. |
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Research, Society and Development |
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Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTHEstudio de cuantificación de compuestos fenólicos, evaluación de actividades antioxidantes y antimicrobianas de la paja del Croton cajucara BENTHEstudo de quantificação dos compostos fenólicos, avaliação das atividades antioxidante e antimicrobiana da casca do caule do Croton cajucara BENTHCroton cajucara BENTHExtractionNatural product.Croton cajucara BENTHExtracciónProducto natural.Croton cajucara BENTHExtraçãoProduto natural.The main objective of this work was to quantify the phenolic compounds, and to evaluate antioxidant and antimicrobial the activity of Croton cajucara BENTH stem bark extracts. An experimental planning (Box Hunter and Hunter) of two factors and two levels determine which variables influenced in the extraction process was used. To the quantification of phenolic compounds was used the methodology of Folin-Ciocalteau. To the antioxidant activity the IC50 method was applied. For the antimicrobial analysis, the microdilution method was employed to indicate the Minimum Inhibitory Concentration (MIC) against the bacterial strains, as well as fungal strain. In the quantification of phenolic compounds, there was a variation between 26.98 and 50.32 mgEAG /g. Regarding antioxidant activity, values from 9.01% to 14.03% were found. For antimicrobial activity, the extracts did not inhibit the growth of the tested bacteria and fungi. All the results were treated statistically and, in general, proved that the best extraction conditions were T = 60 °C and G = 0.10 mm.El objetivo de este trabajo fue cuantificar los compuestos fenólicos y evaluar la actividad antioxidante y antimicrobiana de los extractos de corteza del tallo de Croton cajucara BENTH. Un diseño experimental (Box Hunter y Hunter) de dos factores y dos niveles determina qué variables influyen en el proceso de extracción. Para la cuantificación de compuestos fenólicos se utilizó la metodología de Folin-Ciocalteau. Para la actividad antioxidante se aplicó el método IC50. Para el análisis antimicrobiano se utilizó el método de microdilución para indicar la Concentración Mínima Inhibidora (CMI) frente a cepas bacterianas, así como cepas fúngicas. En la cuantificación de compuestos fenólicos, hubo una variación entre 26,98 y 50,32 mgEAG/g. En cuanto a la actividad antioxidante, se encontraron valores de 9.01% a 14.03%. En cuanto a la actividad antimicrobiana, los extractos no inhibieron el crecimiento de las bacterias y hongos probados. Todos los resultados fueron tratados estadísticamente y, en general, demostraron que las mejores condiciones de extracción fueron T= 60 ° C y G= 0.10 mm.O objetivo deste trabalho foi quantificar os compostos fenólicos e avaliar a atividade antioxidante e antimicrobiana dos extratos da casca do caule do Croton cajucara BENTH. Um planejamento experimental (Box Hunter e Hunter) de dois fatores e dois níveis determinam quais variáveis que influenciam no processo de extração. Para a quantificação dos compostos fenólicos foi utilizada a metodologia de Folin-Ciocalteau. Para a atividade antioxidante foi aplicado o método IC50. Para a análise antimicrobiana, o método de microdiluição foi empregado para indicar a Concentração Inibitória Mínima (CIM) contra as cepas bacterianas, bem como cepas fúngicas. Na quantificação dos compostos fenólicos, houve variação entre 26,98 e 50,32 mgEAG/g. Em relação à atividade antioxidante, foram encontrados valores de 9,01% a 14,03%. Quanto à atividade antimicrobiana, os extratos não inibiram o crescimento das bactérias e fungos testados. Todos os resultados foram tratados estatisticamente e, em geral, comprovaram que as melhores condições de extração foram T= 60 ° C e G= 0,10 mm.Research, Society and Development2020-11-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/974210.33448/rsd-v9i11.9742Research, Society and Development; Vol. 9 No. 11; e1929119742Research, Society and Development; Vol. 9 Núm. 11; e1929119742Research, Society and Development; v. 9 n. 11; e19291197422525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/9742/8678Copyright (c) 2020 Alexandre Augusto Moraes de Souza; Davi do Socorro Barros Brasil; Cintya Cordovil Rodrigues; Sônia Maria de Freitas Almeida; Nayara Maria Monteiro da Silva; Maria Fani Dolabela; Dayse Lúcia do Nascimento Brandão; Luciane do Socorro Nunes dos Santos Brasilhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSouza, Alexandre Augusto Moraes de Brasil, Davi do Socorro Barros Rodrigues, Cintya Cordovil Almeida, Sônia Maria de Freitas Silva, Nayara Maria Monteiro da Dolabela, Maria Fani Brandão, Dayse Lúcia do Nascimento Brasil, Luciane do Socorro Nunes dos Santos2020-12-10T23:37:57Zoai:ojs.pkp.sfu.ca:article/9742Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:31:57.175857Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH Estudio de cuantificación de compuestos fenólicos, evaluación de actividades antioxidantes y antimicrobianas de la paja del Croton cajucara BENTH Estudo de quantificação dos compostos fenólicos, avaliação das atividades antioxidante e antimicrobiana da casca do caule do Croton cajucara BENTH |
title |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH |
spellingShingle |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH Souza, Alexandre Augusto Moraes de Croton cajucara BENTH Extraction Natural product. Croton cajucara BENTH Extracción Producto natural. Croton cajucara BENTH Extração Produto natural. |
title_short |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH |
title_full |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH |
title_fullStr |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH |
title_full_unstemmed |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH |
title_sort |
Study of quantification pf phenolic compounds, evaluation of antioxidant and antimicrobial activities of the stem bark of the Croton cajucara BENTH |
author |
Souza, Alexandre Augusto Moraes de |
author_facet |
Souza, Alexandre Augusto Moraes de Brasil, Davi do Socorro Barros Rodrigues, Cintya Cordovil Almeida, Sônia Maria de Freitas Silva, Nayara Maria Monteiro da Dolabela, Maria Fani Brandão, Dayse Lúcia do Nascimento Brasil, Luciane do Socorro Nunes dos Santos |
author_role |
author |
author2 |
Brasil, Davi do Socorro Barros Rodrigues, Cintya Cordovil Almeida, Sônia Maria de Freitas Silva, Nayara Maria Monteiro da Dolabela, Maria Fani Brandão, Dayse Lúcia do Nascimento Brasil, Luciane do Socorro Nunes dos Santos |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Souza, Alexandre Augusto Moraes de Brasil, Davi do Socorro Barros Rodrigues, Cintya Cordovil Almeida, Sônia Maria de Freitas Silva, Nayara Maria Monteiro da Dolabela, Maria Fani Brandão, Dayse Lúcia do Nascimento Brasil, Luciane do Socorro Nunes dos Santos |
dc.subject.por.fl_str_mv |
Croton cajucara BENTH Extraction Natural product. Croton cajucara BENTH Extracción Producto natural. Croton cajucara BENTH Extração Produto natural. |
topic |
Croton cajucara BENTH Extraction Natural product. Croton cajucara BENTH Extracción Producto natural. Croton cajucara BENTH Extração Produto natural. |
description |
The main objective of this work was to quantify the phenolic compounds, and to evaluate antioxidant and antimicrobial the activity of Croton cajucara BENTH stem bark extracts. An experimental planning (Box Hunter and Hunter) of two factors and two levels determine which variables influenced in the extraction process was used. To the quantification of phenolic compounds was used the methodology of Folin-Ciocalteau. To the antioxidant activity the IC50 method was applied. For the antimicrobial analysis, the microdilution method was employed to indicate the Minimum Inhibitory Concentration (MIC) against the bacterial strains, as well as fungal strain. In the quantification of phenolic compounds, there was a variation between 26.98 and 50.32 mgEAG /g. Regarding antioxidant activity, values from 9.01% to 14.03% were found. For antimicrobial activity, the extracts did not inhibit the growth of the tested bacteria and fungi. All the results were treated statistically and, in general, proved that the best extraction conditions were T = 60 °C and G = 0.10 mm. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-11-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/9742 10.33448/rsd-v9i11.9742 |
url |
https://rsdjournal.org/index.php/rsd/article/view/9742 |
identifier_str_mv |
10.33448/rsd-v9i11.9742 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/9742/8678 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 11; e1929119742 Research, Society and Development; Vol. 9 Núm. 11; e1929119742 Research, Society and Development; v. 9 n. 11; e1929119742 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052742189973504 |