Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/9713 |
Resumo: | In street cocaine production for retail trade, in addition to the active ingredient, other substances are commonly added. The other substances presence, known as adulterants, becomes an additional aggravating factor for user´s health. This work aimed to evaluate qualitatively the cocaine seized by civil police of PI state. For this, 100 cocaine samples seized between the years 2017 and 2018 were used. The GC-MS analyzes identified, mainly, caffeine, phenacetin and levamisole in 58%, 48% and 30% of the samples, respectively. Only 9% the samples did not have adulterants. These adulterants can change cocaine intoxication signs and symptoms since the increase in the power of addiction to the hematological disorders. Finally, is possible to conclude the cocaine seized in the PI does not have a high purity degree and that due the toxicological profile of its main adulterants, these substances identification is a data of great relevance since it helps in understanding of your market and the real risk to user´s health. |
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Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potentialAdulterantes identificados en cocaína comercializada em Piauí - PI: un análisis cualitativo de su potencial toxicológicoAdulterantes identificados na cocaína comercializada no Piauí - PI: uma análise qualitativa do seu potencial toxicológicoGas chromatographyMarketingIntoxication.Cromatografía de gasesMercadoIntoxicación.Cromatografia gasosaMercadoIntoxicação.In street cocaine production for retail trade, in addition to the active ingredient, other substances are commonly added. The other substances presence, known as adulterants, becomes an additional aggravating factor for user´s health. This work aimed to evaluate qualitatively the cocaine seized by civil police of PI state. For this, 100 cocaine samples seized between the years 2017 and 2018 were used. The GC-MS analyzes identified, mainly, caffeine, phenacetin and levamisole in 58%, 48% and 30% of the samples, respectively. Only 9% the samples did not have adulterants. These adulterants can change cocaine intoxication signs and symptoms since the increase in the power of addiction to the hematological disorders. Finally, is possible to conclude the cocaine seized in the PI does not have a high purity degree and that due the toxicological profile of its main adulterants, these substances identification is a data of great relevance since it helps in understanding of your market and the real risk to user´s health.En la producción de cocaína callejera para el comercio minorista, además del ingrediente activo, comúnmente se agregan otras sustancias. La presencia de otras sustancias, conocidas como adulterantes, se convierte en un agravante adicional para la salud de los usuarios. Este trabajo tuvo como objetivo evaluar cualitativamente la cocaína incautada por la policía civil del estado de PI. Para ello se utilizaron 100 muestras de cocaína incautadas entre 2017 y 2018. Los análisis por GC-MS identificaron, principalmente, cafeína, fenacetina y levamisol en el 58%, 48% y 30% de las muestras, respectivamente. Solo el 9% de las muestras no tenían adulterantes. Estos adulterantes pueden alterar los signos y síntomas de la intoxicación por cocaína, desde un aumento de su poder adictivo hasta trastornos hematológicos. Finalmente, es posible concluir que la cocaína incautada en el IP no tiene un alto grado de pureza y que debido al perfil toxicológico de sus principales adulterantes, la identificación de estas sustancias es un dato de gran relevancia ya que ayuda a comprender su mercado y el real. riesgo para la salud de sus usuarios.Na produção da cocaína de rua para o comércio de varejo, além do princípio ativo, outras substâncias são comumente adicionadas. A presença de outras substâncias, conhecidas como adulterantes, torna-se um agravante a mais à saúde dos usuários. Este trabalho teve o objetivo de avaliar qualitativamente a cocaína apreendida pela polícia civil do estado do PI. Para isso, foram utilizadas 100 amostras de cocaína apreendidas entre os anos de 2017 e 2018. As análises por CG-EM identificaram, principalmente, cafeína, fenacetina e levamisol em 58%, 48% e 30% das amostras, respectivamente. Somente 9% das amostras não possuíam adulterantes. Esses adulterantes podem alterar os sinais e sintomas de uma intoxicação por cocaína causando desde um aumento do seu poder adictivo a distúrbios hematológicos. Por fim, é possível concluir que a cocaína apreendida no PI não possui um grau elevado de pureza e que devido ao perfil toxicológico dos seus principais adulterantes a identificação dessas substâncias é um dado de grande relevância já que auxilia na compreensão do seu mercado e do real risco à saúde de seus usuários.Research, Society and Development2020-11-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/971310.33448/rsd-v9i11.9713Research, Society and Development; Vol. 9 No. 11; e2259119713Research, Society and Development; Vol. 9 Núm. 11; e2259119713Research, Society and Development; v. 9 n. 11; e22591197132525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/9713/9620Copyright (c) 2020 Carla Graziela da Silva; Lorena Almeida Lima; Aylla Beatriz Melo de Oliveira ; Larisse Carneiro da Frota Brito ; Lizia Carreiro Tomaz Aguiar ; Nayra Barbosa Alves ; Melquisedeque da Rocha Viana; Cristiano Ribeiro Gonçalves Affonso; Mauricio Pires de Moura do Amaralhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Carla Graziela da Lima, Lorena Almeida Oliveira , Aylla Beatriz Melo deBrito , Larisse Carneiro da Frota Aguiar , Lizia Carreiro Tomaz Alves , Nayra Barbosa Viana, Melquisedeque da Rocha Affonso, Cristiano Ribeiro Gonçalves Amaral, Mauricio Pires de Moura do 2020-12-10T23:37:57Zoai:ojs.pkp.sfu.ca:article/9713Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:31:55.639440Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential Adulterantes identificados en cocaína comercializada em Piauí - PI: un análisis cualitativo de su potencial toxicológico Adulterantes identificados na cocaína comercializada no Piauí - PI: uma análise qualitativa do seu potencial toxicológico |
title |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential |
spellingShingle |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential Silva, Carla Graziela da Gas chromatography Marketing Intoxication. Cromatografía de gases Mercado Intoxicación. Cromatografia gasosa Mercado Intoxicação. |
title_short |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential |
title_full |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential |
title_fullStr |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential |
title_full_unstemmed |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential |
title_sort |
Adulterants identified in cocaine commercialized in Piauí - PI: a qualitative analysis of its toxicological potential |
author |
Silva, Carla Graziela da |
author_facet |
Silva, Carla Graziela da Lima, Lorena Almeida Oliveira , Aylla Beatriz Melo de Brito , Larisse Carneiro da Frota Aguiar , Lizia Carreiro Tomaz Alves , Nayra Barbosa Viana, Melquisedeque da Rocha Affonso, Cristiano Ribeiro Gonçalves Amaral, Mauricio Pires de Moura do |
author_role |
author |
author2 |
Lima, Lorena Almeida Oliveira , Aylla Beatriz Melo de Brito , Larisse Carneiro da Frota Aguiar , Lizia Carreiro Tomaz Alves , Nayra Barbosa Viana, Melquisedeque da Rocha Affonso, Cristiano Ribeiro Gonçalves Amaral, Mauricio Pires de Moura do |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Silva, Carla Graziela da Lima, Lorena Almeida Oliveira , Aylla Beatriz Melo de Brito , Larisse Carneiro da Frota Aguiar , Lizia Carreiro Tomaz Alves , Nayra Barbosa Viana, Melquisedeque da Rocha Affonso, Cristiano Ribeiro Gonçalves Amaral, Mauricio Pires de Moura do |
dc.subject.por.fl_str_mv |
Gas chromatography Marketing Intoxication. Cromatografía de gases Mercado Intoxicación. Cromatografia gasosa Mercado Intoxicação. |
topic |
Gas chromatography Marketing Intoxication. Cromatografía de gases Mercado Intoxicación. Cromatografia gasosa Mercado Intoxicação. |
description |
In street cocaine production for retail trade, in addition to the active ingredient, other substances are commonly added. The other substances presence, known as adulterants, becomes an additional aggravating factor for user´s health. This work aimed to evaluate qualitatively the cocaine seized by civil police of PI state. For this, 100 cocaine samples seized between the years 2017 and 2018 were used. The GC-MS analyzes identified, mainly, caffeine, phenacetin and levamisole in 58%, 48% and 30% of the samples, respectively. Only 9% the samples did not have adulterants. These adulterants can change cocaine intoxication signs and symptoms since the increase in the power of addiction to the hematological disorders. Finally, is possible to conclude the cocaine seized in the PI does not have a high purity degree and that due the toxicological profile of its main adulterants, these substances identification is a data of great relevance since it helps in understanding of your market and the real risk to user´s health. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-11-12 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/9713 10.33448/rsd-v9i11.9713 |
url |
https://rsdjournal.org/index.php/rsd/article/view/9713 |
identifier_str_mv |
10.33448/rsd-v9i11.9713 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/9713/9620 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 11; e2259119713 Research, Society and Development; Vol. 9 Núm. 11; e2259119713 Research, Society and Development; v. 9 n. 11; e2259119713 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052781812514816 |