Obesity as a risk factor for heart failure: overview of systematic reviews
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/24380 |
Resumo: | The overweight and population with obesity has an increased risk of mortality from HF. However, some studies point to the existence of an "obesity paradox" where there could be a protective effect on the relative risk of death by HF in these populations with high BMI. In this way, the present study aimed to investigate obesity as a risk factor for heart failure. For this, an overview of systematic reviews was performed by selecting articles from the following databases: "Pubmed", "Scopus" and "SciElo”. A total of 615 articles were found from this initial search, leaving 59 articles for full-text reading, of which 22 articles were included for data extraction using the predefined inclusion criteria. From these 22 studies 73% were meta-analysis and 64% of the studies are of high methodological quality according to AMSTAR-2. Overweight and obesity have demonstrated a close relationship with the onset and increase of mortality by HF, studies have even been found that point to a gene interference in this relationship. In studies reporting on the obesity paradox, the results pointed to a momentary protection from mortality risk. |
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Obesity as a risk factor for heart failure: overview of systematic reviewsEvaluación de la obesidad como factor de riesgo de insuficiencia cardíaca: descripción general de revisiones sistemáticasAvaliação da obesidade como fator de risco para insuficiência cardíaca: overview de revisões sistemáticasInsuficiência cardíacaObesidadeParadoxo da obesidade.Heart FailureObesityObesity paradox.Insuficiencia cardíacaObesidadParadoja de la obesidade.The overweight and population with obesity has an increased risk of mortality from HF. However, some studies point to the existence of an "obesity paradox" where there could be a protective effect on the relative risk of death by HF in these populations with high BMI. In this way, the present study aimed to investigate obesity as a risk factor for heart failure. For this, an overview of systematic reviews was performed by selecting articles from the following databases: "Pubmed", "Scopus" and "SciElo”. A total of 615 articles were found from this initial search, leaving 59 articles for full-text reading, of which 22 articles were included for data extraction using the predefined inclusion criteria. From these 22 studies 73% were meta-analysis and 64% of the studies are of high methodological quality according to AMSTAR-2. Overweight and obesity have demonstrated a close relationship with the onset and increase of mortality by HF, studies have even been found that point to a gene interference in this relationship. In studies reporting on the obesity paradox, the results pointed to a momentary protection from mortality risk.La población con sobrepeso y obesidad tiene un mayor riesgo de mortalidad por IC. Sin embargo, algunos estudios apuntan a la existencia de una "paradoja de la obesidad" donde podría existir un efecto protector sobre el riesgo relativo de muerte por IC en estas poblaciones con IMC elevado. De esta forma, el presente estudio tuvo como objetivo investigar la obesidad como factor de riesgo de insuficiencia cardíaca. Para ello, se realizó un repaso de revisiones sistemáticas mediante la selección de artículos de las siguientes bases de datos: "Pubmed", "Scopus" y "SciElo". De esta búsqueda inicial se encontraron un total de 615 artículos, quedando 59 artículos para lectura a texto completo, de los cuales se incluyeron 22 artículos para la extracción de datos utilizando los criterios de inclusión predefinidos. De estos 22 estudios el 73% fueron metanálisis y el 64% de los estudios son de alta calidad metodológica según AMSTAR-2. El sobrepeso y la obesidad han demostrado una estrecha relación con sobre la aparición y aumento de la mortalidad por IC, incluso se han encontrado estudios que apuntan a una interferencia genética en esta relación, y en estudios que informan sobre la paradoja de la obesidad, los resultados apuntan a una protección momentánea del riesgo de mortalidad.A população com sobrepeso e obesidade apresentam risco aumentado de mortalidade por IC. No entanto, alguns estudos apontam para a existência de um "paradoxo da obesidade" onde poderia haver um efeito protetor sobre o risco relativo de morte por IC nessas populações com IMC elevado. Dessa forma, o presente estudo teve como objetivo investigar a obesidade como fator de risco para insuficiência cardíaca. Para isso, foi realizada uma overview das revisões sistemáticas selecionando artigos das seguintes bases de dados: "Pubmed", "Scopus" e "SciElo". A partir dessa busca inicial, foram encontrados 615 artigos, restando 59 artigos para leitura na íntegra, dos quais 22 artigos foram incluídos para extração de dados usando os critérios de inclusão predefinidos. Destes 22 estudos 73% eram metanálises e 64% dos estudos são de alta qualidade metodológica de acordo com AMSTAR-2. Sobrepeso e obesidade demonstraram uma estreita relação com o aparecimento e aumento da mortalidade por IC, até mesmo foram encontrados estudos que apontam para uma interferência gênica nessa relação. Em estudos que relatam o paradoxo da obesidade, os resultados apontam para uma proteção momentânea do risco de mortalidade.Research, Society and Development2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2438010.33448/rsd-v11i1.24380Research, Society and Development; Vol. 11 No. 1; e0811124380Research, Society and Development; Vol. 11 Núm. 1; e0811124380Research, Society and Development; v. 11 n. 1; e08111243802525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/24380/21574Copyright (c) 2022 Cleyton Oliveira Bezerra; Rafael Marinho de Lima Paiva; Thamires Lucena da Silva; Vinicius Soares Ribeiro; Cinthia Caldas Rios; Thais Teles de Souza; Walleri Christini Torelli Reishttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBezerra, Cleyton Oliveira Paiva, Rafael Marinho de Lima Silva, Thamires Lucena da Ribeiro, Vinicius Soares Rios, Cinthia Caldas Souza, Thais Teles de Reis, Walleri Christini Torelli 2022-01-16T18:08:18Zoai:ojs.pkp.sfu.ca:article/24380Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:57.266451Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Obesity as a risk factor for heart failure: overview of systematic reviews Evaluación de la obesidad como factor de riesgo de insuficiencia cardíaca: descripción general de revisiones sistemáticas Avaliação da obesidade como fator de risco para insuficiência cardíaca: overview de revisões sistemáticas |
title |
Obesity as a risk factor for heart failure: overview of systematic reviews |
spellingShingle |
Obesity as a risk factor for heart failure: overview of systematic reviews Bezerra, Cleyton Oliveira Insuficiência cardíaca Obesidade Paradoxo da obesidade. Heart Failure Obesity Obesity paradox. Insuficiencia cardíaca Obesidad Paradoja de la obesidade. |
title_short |
Obesity as a risk factor for heart failure: overview of systematic reviews |
title_full |
Obesity as a risk factor for heart failure: overview of systematic reviews |
title_fullStr |
Obesity as a risk factor for heart failure: overview of systematic reviews |
title_full_unstemmed |
Obesity as a risk factor for heart failure: overview of systematic reviews |
title_sort |
Obesity as a risk factor for heart failure: overview of systematic reviews |
author |
Bezerra, Cleyton Oliveira |
author_facet |
Bezerra, Cleyton Oliveira Paiva, Rafael Marinho de Lima Silva, Thamires Lucena da Ribeiro, Vinicius Soares Rios, Cinthia Caldas Souza, Thais Teles de Reis, Walleri Christini Torelli |
author_role |
author |
author2 |
Paiva, Rafael Marinho de Lima Silva, Thamires Lucena da Ribeiro, Vinicius Soares Rios, Cinthia Caldas Souza, Thais Teles de Reis, Walleri Christini Torelli |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Bezerra, Cleyton Oliveira Paiva, Rafael Marinho de Lima Silva, Thamires Lucena da Ribeiro, Vinicius Soares Rios, Cinthia Caldas Souza, Thais Teles de Reis, Walleri Christini Torelli |
dc.subject.por.fl_str_mv |
Insuficiência cardíaca Obesidade Paradoxo da obesidade. Heart Failure Obesity Obesity paradox. Insuficiencia cardíaca Obesidad Paradoja de la obesidade. |
topic |
Insuficiência cardíaca Obesidade Paradoxo da obesidade. Heart Failure Obesity Obesity paradox. Insuficiencia cardíaca Obesidad Paradoja de la obesidade. |
description |
The overweight and population with obesity has an increased risk of mortality from HF. However, some studies point to the existence of an "obesity paradox" where there could be a protective effect on the relative risk of death by HF in these populations with high BMI. In this way, the present study aimed to investigate obesity as a risk factor for heart failure. For this, an overview of systematic reviews was performed by selecting articles from the following databases: "Pubmed", "Scopus" and "SciElo”. A total of 615 articles were found from this initial search, leaving 59 articles for full-text reading, of which 22 articles were included for data extraction using the predefined inclusion criteria. From these 22 studies 73% were meta-analysis and 64% of the studies are of high methodological quality according to AMSTAR-2. Overweight and obesity have demonstrated a close relationship with the onset and increase of mortality by HF, studies have even been found that point to a gene interference in this relationship. In studies reporting on the obesity paradox, the results pointed to a momentary protection from mortality risk. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/24380 10.33448/rsd-v11i1.24380 |
url |
https://rsdjournal.org/index.php/rsd/article/view/24380 |
identifier_str_mv |
10.33448/rsd-v11i1.24380 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/24380/21574 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 1; e0811124380 Research, Society and Development; Vol. 11 Núm. 1; e0811124380 Research, Society and Development; v. 11 n. 1; e0811124380 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052699756199936 |