Applicability of saliva in the diagnosis of COVID-19: a review

Detalhes bibliográficos
Autor(a) principal: Lemos, Éverson de Andrade
Data de Publicação: 2020
Outros Autores: Cabral, Gustavo de Amorim Barbosa, Fernandes Neto, José de Alencar, Catão, Maria Helena Chaves de Vasconcelos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/7991
Resumo: In 2020, the World Health Organization (WHO) classified COVID-19 as a global pandemic. Since then, there is a need for new methods to facilitate the diagnosis and control of this disease. Currently, reverse transcription followed by real-time polymerase chain reaction (rRT-PCR) of respiratory samples obtained by swabs represents the gold standard in the qualitative detection of Sars-CoV-2 infection. However, this type of collection has several disadvantages, making saliva a potential tool for the diagnosis of COVID-19. Thus, the aim of this study is to evaluate, through a systematic review of current scientific literature, the applicability of saliva for the diagnosis of COVID-19 in comparison to current methods. A search was carried out in MEDLINE, SciELO, Scopus and Web of Science databases, using descriptors, strategies and pre-established criteria by two independent evaluators, followed by a manual search in the references of articles selected for full reading. The research strategies identified 476 studies and 1 study was added through manual search. After analysis, 200 articles were excluded because they were duplicated among results found in databases. With the completion of the screening process, 12 articles were included in this review. It was concluded that it is necessary to produce new studies in order to obtain even more reliable and effective data about the use of saliva in the diagnosis of COVID-19. However, studies have shown that this material can be an excellent alternative sample for the detection of SARS-CoV-2.
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spelling Applicability of saliva in the diagnosis of COVID-19: a reviewAplicabilidad de la saliva en el diagnóstico de COVID-19: una revisiónAplicabilidade da saliva no diagnóstico da COVID-19: uma revisãoCoronavírusSalivaControle de infecçãoDoenças infecciosasCoronavirusSalivaControl de infeccionesEnfermidades infecciosasCoronavirusSalivaInfection controlInfectious diseasesIn 2020, the World Health Organization (WHO) classified COVID-19 as a global pandemic. Since then, there is a need for new methods to facilitate the diagnosis and control of this disease. Currently, reverse transcription followed by real-time polymerase chain reaction (rRT-PCR) of respiratory samples obtained by swabs represents the gold standard in the qualitative detection of Sars-CoV-2 infection. However, this type of collection has several disadvantages, making saliva a potential tool for the diagnosis of COVID-19. Thus, the aim of this study is to evaluate, through a systematic review of current scientific literature, the applicability of saliva for the diagnosis of COVID-19 in comparison to current methods. A search was carried out in MEDLINE, SciELO, Scopus and Web of Science databases, using descriptors, strategies and pre-established criteria by two independent evaluators, followed by a manual search in the references of articles selected for full reading. The research strategies identified 476 studies and 1 study was added through manual search. After analysis, 200 articles were excluded because they were duplicated among results found in databases. With the completion of the screening process, 12 articles were included in this review. It was concluded that it is necessary to produce new studies in order to obtain even more reliable and effective data about the use of saliva in the diagnosis of COVID-19. However, studies have shown that this material can be an excellent alternative sample for the detection of SARS-CoV-2.En 2020, la Organización Mundial de la Salud (OMS) clasificó al COVID-19 como una pandemia mundial. Desde entonces, existe la necesidad de métodos que faciliten el diagnóstico y control de esta enfermedad. Actualmente, la transcripción inversa seguida de la reacción en cadena de la polimerasa en tiempo real (rRT-PCR) de muestras respiratorias obtenidas mediante hisopos representa el estándar de oro en la detección cualitativa de la infección por Sars-CoV-2. Este tipo de recolección tiene desventajas, por lo que la saliva es una herramienta potencial para el diagnóstico de COVID-19. Por tanto, el objetivo de este estudio es evaluar, mediante una revisión sistemática de la literatura, la aplicabilidad de la saliva para el diagnóstico de COVID-19 en comparación con los métodos actuales utilizados. Se realizó una búsqueda en las bases PubMed, SciELO, Scopus y Web of Science, utilizando descriptores, estrategias y criterios preestablecidos, por dos evaluadores, seguida de una búsqueda manual en las referencias de los artículos seleccionados para lectura completa. Las estrategias identificaron 476 estudios y se agregó 1 estudio mediante búsqueda manual. Tras el análisis, se excluyeron 200 por estar duplicados entre los resultados encontrados en las bases. Con la finalización del proceso, se incluyeron 12 artículos en esta revisión. Se concluyó que es necesario producir estudios para obtener datos aún más confiables y efectivos sobre el uso de la saliva en el diagnóstico de COVID-19. Sin embargo, la investigación ha demostrado que este material puede ser un excelente tipo de muestra alternativa para la detección del SARS-CoV-2.Em 2020, a Organização Mundial da Saúde (OMS) classificou a COVID-19 como uma pandemia global. Desde então, existe a necessidade de novos métodos que facilitem o diagnóstico e controle dessa doença. Atualmente, a transcrição reversa seguida de reação em cadeia da polimerase em tempo real (rRT-PCR) de amostras respiratórias obtidas por swabs representa o padrão ouro na detecção qualitativa da infecção por Sars-CoV-2. Contudo, esse tipo de coleta apresenta diversas desvantagens, tornando a saliva uma potencial ferramenta para o diagnóstico da COVID-19. Diante disso, o objetivo desse estudo é avaliar, por meio de uma revisão sistematizada da literatura científica atual, a aplicabilidade da saliva para o diagnóstico da COVID-19 em comparação aos atuais métodos utilizados. Realizou-se uma busca nas bases PubMed, SciELO, Scopus e Web of Science, utilizando descritores, estratégias e critérios preestabelecidos, por dois avaliadores, de forma independente, seguida de uma busca manual nas referências do artigos selecionados para leitura integral. As estratégias de pesquisa identificaram 476 estudos e 1 estudo foi adicionado por meio de busca manual. Após análise, 200 artigos foram excluídos por estarem duplicados entre os resultados encontrados nas bases. Com a finalização do processo de triagem, 12 artigos foram incluídos nesta revisão. Concluiu-se que é necessário a produção de novos estudos a fim de se obter dados ainda mais confiáveis e efetivos acerca do uso da saliva no diagnóstico da COVID-19. Contudo, as pesquisas têm demonstrado que esse material pode ser um excelente tipo de amostra alternativa para a detecção do SARS-CoV-2.Research, Society and Development2020-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/799110.33448/rsd-v9i9.7991Research, Society and Development; Vol. 9 No. 9; e636997991Research, Society and Development; Vol. 9 Núm. 9; e636997991Research, Society and Development; v. 9 n. 9; e6369979912525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/7991/6834Copyright (c) 2020 Éverson de Andrade Lemos; Gustavo de Amorim Barbosa Cabral; José de Alencar Fernandes Neto; Maria Helena Chaves de Vasconcelos Catãohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLemos, Éverson de AndradeCabral, Gustavo de Amorim BarbosaFernandes Neto, José de AlencarCatão, Maria Helena Chaves de Vasconcelos2020-09-18T01:42:11Zoai:ojs.pkp.sfu.ca:article/7991Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:30:34.335187Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Applicability of saliva in the diagnosis of COVID-19: a review
Aplicabilidad de la saliva en el diagnóstico de COVID-19: una revisión
Aplicabilidade da saliva no diagnóstico da COVID-19: uma revisão
title Applicability of saliva in the diagnosis of COVID-19: a review
spellingShingle Applicability of saliva in the diagnosis of COVID-19: a review
Lemos, Éverson de Andrade
Coronavírus
Saliva
Controle de infecção
Doenças infecciosas
Coronavirus
Saliva
Control de infecciones
Enfermidades infecciosas
Coronavirus
Saliva
Infection control
Infectious diseases
title_short Applicability of saliva in the diagnosis of COVID-19: a review
title_full Applicability of saliva in the diagnosis of COVID-19: a review
title_fullStr Applicability of saliva in the diagnosis of COVID-19: a review
title_full_unstemmed Applicability of saliva in the diagnosis of COVID-19: a review
title_sort Applicability of saliva in the diagnosis of COVID-19: a review
author Lemos, Éverson de Andrade
author_facet Lemos, Éverson de Andrade
Cabral, Gustavo de Amorim Barbosa
Fernandes Neto, José de Alencar
Catão, Maria Helena Chaves de Vasconcelos
author_role author
author2 Cabral, Gustavo de Amorim Barbosa
Fernandes Neto, José de Alencar
Catão, Maria Helena Chaves de Vasconcelos
author2_role author
author
author
dc.contributor.author.fl_str_mv Lemos, Éverson de Andrade
Cabral, Gustavo de Amorim Barbosa
Fernandes Neto, José de Alencar
Catão, Maria Helena Chaves de Vasconcelos
dc.subject.por.fl_str_mv Coronavírus
Saliva
Controle de infecção
Doenças infecciosas
Coronavirus
Saliva
Control de infecciones
Enfermidades infecciosas
Coronavirus
Saliva
Infection control
Infectious diseases
topic Coronavírus
Saliva
Controle de infecção
Doenças infecciosas
Coronavirus
Saliva
Control de infecciones
Enfermidades infecciosas
Coronavirus
Saliva
Infection control
Infectious diseases
description In 2020, the World Health Organization (WHO) classified COVID-19 as a global pandemic. Since then, there is a need for new methods to facilitate the diagnosis and control of this disease. Currently, reverse transcription followed by real-time polymerase chain reaction (rRT-PCR) of respiratory samples obtained by swabs represents the gold standard in the qualitative detection of Sars-CoV-2 infection. However, this type of collection has several disadvantages, making saliva a potential tool for the diagnosis of COVID-19. Thus, the aim of this study is to evaluate, through a systematic review of current scientific literature, the applicability of saliva for the diagnosis of COVID-19 in comparison to current methods. A search was carried out in MEDLINE, SciELO, Scopus and Web of Science databases, using descriptors, strategies and pre-established criteria by two independent evaluators, followed by a manual search in the references of articles selected for full reading. The research strategies identified 476 studies and 1 study was added through manual search. After analysis, 200 articles were excluded because they were duplicated among results found in databases. With the completion of the screening process, 12 articles were included in this review. It was concluded that it is necessary to produce new studies in order to obtain even more reliable and effective data about the use of saliva in the diagnosis of COVID-19. However, studies have shown that this material can be an excellent alternative sample for the detection of SARS-CoV-2.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/7991
10.33448/rsd-v9i9.7991
url https://rsdjournal.org/index.php/rsd/article/view/7991
identifier_str_mv 10.33448/rsd-v9i9.7991
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/7991/6834
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 9; e636997991
Research, Society and Development; Vol. 9 Núm. 9; e636997991
Research, Society and Development; v. 9 n. 9; e636997991
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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