Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.

Detalhes bibliográficos
Autor(a) principal: Quintão, Glauber Cisneiros
Data de Publicação: 2022
Outros Autores: Cavalcante, Giani Maria, Lins, Luiz Andrade
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/27057
Resumo: The Brachymenium exile is the species of Bryaceae family, the family of bryophytes best represented in cerrado biome. The potential for biotechnological and biopharmaceutical applications of bryophytes have been investigated sharply. The aimed to investigate the cicatrizing potential of ethanolic extract of B. exile by scratch assay. The in vitro study was using the spreading and migration capabilities of fibroblast cell line using the extract of B. exile. the extract of B. exile allowed the cellular migration in 76% more that the control and not citotoxic assay in fibroblast cell line (3T3-L1). The extract of B. exile showed activity potential wound healing in vitro assay.
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spelling Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.Investigación de la cicatrización in vitro de la especie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.Investigação da cicatrização in vitro da espécie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.BriófitasAtividades biológicasCicatrização. BriófitosActividades biológicasCuración.BryophytesBiological activitiesHealing.The Brachymenium exile is the species of Bryaceae family, the family of bryophytes best represented in cerrado biome. The potential for biotechnological and biopharmaceutical applications of bryophytes have been investigated sharply. The aimed to investigate the cicatrizing potential of ethanolic extract of B. exile by scratch assay. The in vitro study was using the spreading and migration capabilities of fibroblast cell line using the extract of B. exile. the extract of B. exile allowed the cellular migration in 76% more that the control and not citotoxic assay in fibroblast cell line (3T3-L1). The extract of B. exile showed activity potential wound healing in vitro assay.Brachymenium exile es una especie de la familia Bryaceae, la familia de briófitas mejor representada en el bioma del cerrado. Se ha investigado intensamente el potencial de las aplicaciones biotecnológicas y biofarmacéuticas de las briófitas. El objetivo fue investigar el potencial cicatrizante del extracto metanólico de B. exile mediante ensayo de migración celular. El estudio in vitro evaluó la capacidad de propagación y migración de los fibroblastos utilizando el extracto metanólico de B. exile. El resultado mostró que el extracto de B. exile permitió la migración celular del 76% de las células y no presentó citotoxicidad para células del fibroblasto (3T3-L1). El extracto de B. exile mostró un potencial significativo para la actividad cicatrizante en un ensayo in vitro.Brachymenium exile é uma espécie da família Bryaceae, a família de briófitas mais bem representada no bioma cerrado. O potencial para aplicações biotecnológicas e biofarmacêuticas de briófitas tem sido investigado intensivamente. O objetivo foi investigar o potencial cicatrizante do extrato metanólico de B. exile por ensaio de migração celular. O estudo in vitro avaliou a capacidade de propagação e migração da linhagem celular de fibroblastos usando o extrato metanólico de B. exile. O resultado mostrou que o extrato de B. exile permitiu a migração celular de 76% das células e não apresentou citotoxicidade para as células da linhagem de fibroblastos (3T3-L1). O extrato de B. exile apresentou potencial de atividade cicatrizante significativo em ensaio in vitro.Research, Society and Development2022-03-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2705710.33448/rsd-v11i4.27057Research, Society and Development; Vol. 11 No. 4; e6311427057Research, Society and Development; Vol. 11 Núm. 4; e6311427057Research, Society and Development; v. 11 n. 4; e63114270572525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/27057/23673Copyright (c) 2022 Glauber Cisneiros Quintão; Giani Maria Cavalcante; Luiz Andrade Linshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessQuintão, Glauber Cisneiros Cavalcante, Giani MariaLins, Luiz Andrade2022-03-27T17:17:09Zoai:ojs.pkp.sfu.ca:article/27057Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:54.291978Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
Investigación de la cicatrización in vitro de la especie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
Investigação da cicatrização in vitro da espécie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
title Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
spellingShingle Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
Quintão, Glauber Cisneiros
Briófitas
Atividades biológicas
Cicatrização.
Briófitos
Actividades biológicas
Curación.
Bryophytes
Biological activities
Healing.
title_short Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
title_full Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
title_fullStr Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
title_full_unstemmed Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
title_sort Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
author Quintão, Glauber Cisneiros
author_facet Quintão, Glauber Cisneiros
Cavalcante, Giani Maria
Lins, Luiz Andrade
author_role author
author2 Cavalcante, Giani Maria
Lins, Luiz Andrade
author2_role author
author
dc.contributor.author.fl_str_mv Quintão, Glauber Cisneiros
Cavalcante, Giani Maria
Lins, Luiz Andrade
dc.subject.por.fl_str_mv Briófitas
Atividades biológicas
Cicatrização.
Briófitos
Actividades biológicas
Curación.
Bryophytes
Biological activities
Healing.
topic Briófitas
Atividades biológicas
Cicatrização.
Briófitos
Actividades biológicas
Curación.
Bryophytes
Biological activities
Healing.
description The Brachymenium exile is the species of Bryaceae family, the family of bryophytes best represented in cerrado biome. The potential for biotechnological and biopharmaceutical applications of bryophytes have been investigated sharply. The aimed to investigate the cicatrizing potential of ethanolic extract of B. exile by scratch assay. The in vitro study was using the spreading and migration capabilities of fibroblast cell line using the extract of B. exile. the extract of B. exile allowed the cellular migration in 76% more that the control and not citotoxic assay in fibroblast cell line (3T3-L1). The extract of B. exile showed activity potential wound healing in vitro assay.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-11
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27057
10.33448/rsd-v11i4.27057
url https://rsdjournal.org/index.php/rsd/article/view/27057
identifier_str_mv 10.33448/rsd-v11i4.27057
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27057/23673
dc.rights.driver.fl_str_mv Copyright (c) 2022 Glauber Cisneiros Quintão; Giani Maria Cavalcante; Luiz Andrade Lins
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Glauber Cisneiros Quintão; Giani Maria Cavalcante; Luiz Andrade Lins
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 4; e6311427057
Research, Society and Development; Vol. 11 Núm. 4; e6311427057
Research, Society and Development; v. 11 n. 4; e6311427057
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052706819407872

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