Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/27057 |
Resumo: | The Brachymenium exile is the species of Bryaceae family, the family of bryophytes best represented in cerrado biome. The potential for biotechnological and biopharmaceutical applications of bryophytes have been investigated sharply. The aimed to investigate the cicatrizing potential of ethanolic extract of B. exile by scratch assay. The in vitro study was using the spreading and migration capabilities of fibroblast cell line using the extract of B. exile. the extract of B. exile allowed the cellular migration in 76% more that the control and not citotoxic assay in fibroblast cell line (3T3-L1). The extract of B. exile showed activity potential wound healing in vitro assay. |
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Research, Society and Development |
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Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.Investigación de la cicatrización in vitro de la especie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.Investigação da cicatrização in vitro da espécie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac.BriófitasAtividades biológicasCicatrização. BriófitosActividades biológicasCuración.BryophytesBiological activitiesHealing.The Brachymenium exile is the species of Bryaceae family, the family of bryophytes best represented in cerrado biome. The potential for biotechnological and biopharmaceutical applications of bryophytes have been investigated sharply. The aimed to investigate the cicatrizing potential of ethanolic extract of B. exile by scratch assay. The in vitro study was using the spreading and migration capabilities of fibroblast cell line using the extract of B. exile. the extract of B. exile allowed the cellular migration in 76% more that the control and not citotoxic assay in fibroblast cell line (3T3-L1). The extract of B. exile showed activity potential wound healing in vitro assay.Brachymenium exile es una especie de la familia Bryaceae, la familia de briófitas mejor representada en el bioma del cerrado. Se ha investigado intensamente el potencial de las aplicaciones biotecnológicas y biofarmacéuticas de las briófitas. El objetivo fue investigar el potencial cicatrizante del extracto metanólico de B. exile mediante ensayo de migración celular. El estudio in vitro evaluó la capacidad de propagación y migración de los fibroblastos utilizando el extracto metanólico de B. exile. El resultado mostró que el extracto de B. exile permitió la migración celular del 76% de las células y no presentó citotoxicidad para células del fibroblasto (3T3-L1). El extracto de B. exile mostró un potencial significativo para la actividad cicatrizante en un ensayo in vitro.Brachymenium exile é uma espécie da família Bryaceae, a família de briófitas mais bem representada no bioma cerrado. O potencial para aplicações biotecnológicas e biofarmacêuticas de briófitas tem sido investigado intensivamente. O objetivo foi investigar o potencial cicatrizante do extrato metanólico de B. exile por ensaio de migração celular. O estudo in vitro avaliou a capacidade de propagação e migração da linhagem celular de fibroblastos usando o extrato metanólico de B. exile. O resultado mostrou que o extrato de B. exile permitiu a migração celular de 76% das células e não apresentou citotoxicidade para as células da linhagem de fibroblastos (3T3-L1). O extrato de B. exile apresentou potencial de atividade cicatrizante significativo em ensaio in vitro.Research, Society and Development2022-03-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2705710.33448/rsd-v11i4.27057Research, Society and Development; Vol. 11 No. 4; e6311427057Research, Society and Development; Vol. 11 Núm. 4; e6311427057Research, Society and Development; v. 11 n. 4; e63114270572525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/27057/23673Copyright (c) 2022 Glauber Cisneiros Quintão; Giani Maria Cavalcante; Luiz Andrade Linshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessQuintão, Glauber Cisneiros Cavalcante, Giani MariaLins, Luiz Andrade2022-03-27T17:17:09Zoai:ojs.pkp.sfu.ca:article/27057Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:54.291978Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. Investigación de la cicatrización in vitro de la especie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. Investigação da cicatrização in vitro da espécie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. |
title |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. |
spellingShingle |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. Quintão, Glauber Cisneiros Briófitas Atividades biológicas Cicatrização. Briófitos Actividades biológicas Curación. Bryophytes Biological activities Healing. |
title_short |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. |
title_full |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. |
title_fullStr |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. |
title_full_unstemmed |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. |
title_sort |
Investigation of wound healing in vitro of specie Brachymenium exile (Dozy & Molk.) Bosch & Sande Lac. |
author |
Quintão, Glauber Cisneiros |
author_facet |
Quintão, Glauber Cisneiros Cavalcante, Giani Maria Lins, Luiz Andrade |
author_role |
author |
author2 |
Cavalcante, Giani Maria Lins, Luiz Andrade |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Quintão, Glauber Cisneiros Cavalcante, Giani Maria Lins, Luiz Andrade |
dc.subject.por.fl_str_mv |
Briófitas Atividades biológicas Cicatrização. Briófitos Actividades biológicas Curación. Bryophytes Biological activities Healing. |
topic |
Briófitas Atividades biológicas Cicatrização. Briófitos Actividades biológicas Curación. Bryophytes Biological activities Healing. |
description |
The Brachymenium exile is the species of Bryaceae family, the family of bryophytes best represented in cerrado biome. The potential for biotechnological and biopharmaceutical applications of bryophytes have been investigated sharply. The aimed to investigate the cicatrizing potential of ethanolic extract of B. exile by scratch assay. The in vitro study was using the spreading and migration capabilities of fibroblast cell line using the extract of B. exile. the extract of B. exile allowed the cellular migration in 76% more that the control and not citotoxic assay in fibroblast cell line (3T3-L1). The extract of B. exile showed activity potential wound healing in vitro assay. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/27057 10.33448/rsd-v11i4.27057 |
url |
https://rsdjournal.org/index.php/rsd/article/view/27057 |
identifier_str_mv |
10.33448/rsd-v11i4.27057 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/27057/23673 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Glauber Cisneiros Quintão; Giani Maria Cavalcante; Luiz Andrade Lins https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Glauber Cisneiros Quintão; Giani Maria Cavalcante; Luiz Andrade Lins https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 4; e6311427057 Research, Society and Development; Vol. 11 Núm. 4; e6311427057 Research, Society and Development; v. 11 n. 4; e6311427057 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052706819407872 |