Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report

Detalhes bibliográficos
Autor(a) principal: Dal Prá, Ketelin
Data de Publicação: 2022
Outros Autores: Tristão, Stefanny da Silva Santucci Assis, Franco, Juliana Bertoldi, Matias, Diogo Toledo, Peres, Maria Paula Siqueira de Melo, Ribas, Priscila Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/20338
Resumo: Toxic epidermal necrolysis (TEN) is a mucocutaneous disorder characterized by the detachment of epidermal and mucous tissues and areas of necrosis, resulting from hypersensitivity reactions to different drugs. We report a clinical case of a 19-year-old male patient diagnosed with TEN, with 90% involvement of the body surface and severe oral involvement. The patient was monitored by dentists from the multidisciplinary team of an intensive care unit, where adjuvant treatment was performed through photobiomodulation to control pain and regenerate the oral mucosa. The case represents the importance of early performance in oral TEN injuries and the role of the multidisciplinary team for comprehensive treatment.
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spelling Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case reportManifestaciones orales y manejo dental de la necrólisis epidérmica tóxica en una unidad de cuidados intensivos: reporte de casoManifestações orais e manejo odontológico da necrólise epidérmica tóxica em unidade de terapia intensiva: relato de caso Necrólisis epidérmica tóxicaHipersensibilidad a fármacosUnidad de cuidados intensivosManifestaciones oralesFotobiomodulaciónCicatrización de heridas.Necrólise epidérmica tóxicaHipersensibilidade a medicamentosUnidade de terapia intensivaManifestações oraisFotobiomodulaçãoCicatrização de feridas.Toxic epidermal necrolysisDrug hypersensitivityIntensive care unitOral manifestationsPhotobiomodulationWound healing.Toxic epidermal necrolysis (TEN) is a mucocutaneous disorder characterized by the detachment of epidermal and mucous tissues and areas of necrosis, resulting from hypersensitivity reactions to different drugs. We report a clinical case of a 19-year-old male patient diagnosed with TEN, with 90% involvement of the body surface and severe oral involvement. The patient was monitored by dentists from the multidisciplinary team of an intensive care unit, where adjuvant treatment was performed through photobiomodulation to control pain and regenerate the oral mucosa. The case represents the importance of early performance in oral TEN injuries and the role of the multidisciplinary team for comprehensive treatment.La necrólisis epidérmica tóxica (NET) es un trastorno mucocutáneo caracterizado por desprendimiento de tejidos epidérmicos y mucosos y áreas de necrosis, como resultado de reacciones de hipersensibilidad a diferentes fármacos. La incidencia es de 1 a 2 casos por millón, tiene una alta tasa de mortalidad y requiere atención multidisciplinar. Las manifestaciones bucales son erosiones, ampollas y ulceraciones extremadamente dolorosas, con gran potencial infeccioso. Presentamos el caso clínico de un paciente masculino de 19 años diagnosticado de NET, con afectación del 90% de la superficie corporal y afectación oral grave. El paciente fue monitoreado por el equipo odontológico incluido en el equipo multidisciplinario de una unidad de cuidados intensivos, donde se realizó tratamiento adyuvante mediante fotobiomodulación para el control del dolor y la regeneración de la mucosa bucal, además de protocolos de higiene bucal e hidratación constante. El caso representa la importancia de la evaluación y actuación precoces en las lesiones bucales de la NET y el papel fundamental del equipo multidisciplinar para el tratamiento integral.A Necrólise epidérmica tóxica (NET) é uma desordem muco-cutânea caracterizada pelo descolamento de tecidos epidérmicos e mucosos e áreas de necrose, decorrentes de reações de hipersensibilidade a distintos fármacos. A incidência é de 1 a 2 casos por milhão, possui alta taxa de mortalidade e requer cuidados multidisciplinares. As manifestações bucais são erosões, bolhas e ulcerações extremamente dolorosas, com grande potencial de infecção. Relatamos um caso clínico de paciente do sexo masculino, 19 anos, diagnosticado com NET, com acometimento de 90% da superfície corpórea e envolvimento oral grave. O paciente recebeu acompanhamento pela equipe de odontologia inserida na equipe multidisciplinar de uma unidade de terapia intensiva, onde foi realizado tratamento adjuvante através da fotobiomodulação para controle de dor e regeneração da mucosa oral, além de protocolos de higiene oral e hidratação constante. O caso representa a importância da avaliação e atuação precoce nas lesões orais de NET e o papel fundamental da equipe multidisciplinar para um tratamento integral. Research, Society and Development2022-07-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2033810.33448/rsd-v11i9.20338Research, Society and Development; Vol. 11 No. 9; e2611920338Research, Society and Development; Vol. 11 Núm. 9; e2611920338Research, Society and Development; v. 11 n. 9; e26119203382525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/20338/27357Copyright (c) 2022 Ketelin Dal Prá; Stefanny da Silva Santucci Assis Tristão; Juliana Bertoldi Franco; Diogo Toledo Matias; Maria Paula Siqueira de Melo Peres; Priscila Fernandes Ribashttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDal Prá, KetelinTristão, Stefanny da Silva Santucci Assis Franco, Juliana Bertoldi Matias, Diogo Toledo Peres, Maria Paula Siqueira de Melo Ribas, Priscila Fernandes 2022-07-21T12:36:16Zoai:ojs.pkp.sfu.ca:article/20338Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:00.994566Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
Manifestaciones orales y manejo dental de la necrólisis epidérmica tóxica en una unidad de cuidados intensivos: reporte de caso
Manifestações orais e manejo odontológico da necrólise epidérmica tóxica em unidade de terapia intensiva: relato de caso
title Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
spellingShingle Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
Dal Prá, Ketelin
Necrólisis epidérmica tóxica
Hipersensibilidad a fármacos
Unidad de cuidados intensivos
Manifestaciones orales
Fotobiomodulación
Cicatrización de heridas.
Necrólise epidérmica tóxica
Hipersensibilidade a medicamentos
Unidade de terapia intensiva
Manifestações orais
Fotobiomodulação
Cicatrização de feridas.
Toxic epidermal necrolysis
Drug hypersensitivity
Intensive care unit
Oral manifestations
Photobiomodulation
Wound healing.
title_short Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
title_full Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
title_fullStr Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
title_full_unstemmed Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
title_sort Oral manifestations and management of toxic epidermal necrolysis in an intensive care unit: case report
author Dal Prá, Ketelin
author_facet Dal Prá, Ketelin
Tristão, Stefanny da Silva Santucci Assis
Franco, Juliana Bertoldi
Matias, Diogo Toledo
Peres, Maria Paula Siqueira de Melo
Ribas, Priscila Fernandes
author_role author
author2 Tristão, Stefanny da Silva Santucci Assis
Franco, Juliana Bertoldi
Matias, Diogo Toledo
Peres, Maria Paula Siqueira de Melo
Ribas, Priscila Fernandes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Dal Prá, Ketelin
Tristão, Stefanny da Silva Santucci Assis
Franco, Juliana Bertoldi
Matias, Diogo Toledo
Peres, Maria Paula Siqueira de Melo
Ribas, Priscila Fernandes
dc.subject.por.fl_str_mv Necrólisis epidérmica tóxica
Hipersensibilidad a fármacos
Unidad de cuidados intensivos
Manifestaciones orales
Fotobiomodulación
Cicatrización de heridas.
Necrólise epidérmica tóxica
Hipersensibilidade a medicamentos
Unidade de terapia intensiva
Manifestações orais
Fotobiomodulação
Cicatrização de feridas.
Toxic epidermal necrolysis
Drug hypersensitivity
Intensive care unit
Oral manifestations
Photobiomodulation
Wound healing.
topic Necrólisis epidérmica tóxica
Hipersensibilidad a fármacos
Unidad de cuidados intensivos
Manifestaciones orales
Fotobiomodulación
Cicatrización de heridas.
Necrólise epidérmica tóxica
Hipersensibilidade a medicamentos
Unidade de terapia intensiva
Manifestações orais
Fotobiomodulação
Cicatrização de feridas.
Toxic epidermal necrolysis
Drug hypersensitivity
Intensive care unit
Oral manifestations
Photobiomodulation
Wound healing.
description Toxic epidermal necrolysis (TEN) is a mucocutaneous disorder characterized by the detachment of epidermal and mucous tissues and areas of necrosis, resulting from hypersensitivity reactions to different drugs. We report a clinical case of a 19-year-old male patient diagnosed with TEN, with 90% involvement of the body surface and severe oral involvement. The patient was monitored by dentists from the multidisciplinary team of an intensive care unit, where adjuvant treatment was performed through photobiomodulation to control pain and regenerate the oral mucosa. The case represents the importance of early performance in oral TEN injuries and the role of the multidisciplinary team for comprehensive treatment.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-16
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/20338
10.33448/rsd-v11i9.20338
url https://rsdjournal.org/index.php/rsd/article/view/20338
identifier_str_mv 10.33448/rsd-v11i9.20338
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/20338/27357
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 9; e2611920338
Research, Society and Development; Vol. 11 Núm. 9; e2611920338
Research, Society and Development; v. 11 n. 9; e2611920338
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052755786858496

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