Male infertility: main causes and emerging therapies, a review

Detalhes bibliográficos
Autor(a) principal: Marconato, Tauana Caroline
Data de Publicação: 2022
Outros Autores: Donne, Ricardo Ditzel Delle, Romano, Renata Marino, Romano, Marco Aurelio
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33139
Resumo: The concept of infertility and its predisposing factors are still in the process of being discovered. Nowadays, it is known that most cases of infertility are linked to men and that their routine and life habits are relevant in this regard. The central one was oxidative stress, which stems from alcohol activities like other environmental consumption activities, directly affecting by interference, for example, in the production of spermatogenic substances and not environmentally suitable. After applying the selection criteria, 48 related to male infertility, triggers, among oxidative stress, as therapeutic mechanisms were analyzed, being articles developed for this, using SciELO and PubMed as tools. The influence of factors such as lifestyle, diet and obesity, in addition to the genetic factor, on the etiology of infertility was evidenced. Among the measures, curative measures on cells of genetic studies as well as in the field of natural medicine, still in development and sometimes ignored, together with antioxidant supplements are particularized. After a study of excellence for the construction of a project of better quality, it is necessary to develop a project of excellence of quality for family members, it is necessary to develop a project of excellence for family members in pairs, which offers an education work that is also in family quality studies, directly to employees due to their infertility condition. The present review aims to describe the main causes of male infertility, with emphasis on oxidative stress, as well as the interventions being developed and working on its treatment.
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spelling Male infertility: main causes and emerging therapies, a reviewInfertilidad masculina: causas principales y terapias emergentes, una revisiónInfertilidade masculina: principais causas e terapêuticas emergentes, uma revisãoMale infertilityOxidative stressReproduction.Infertilidad masculinaEstrés oxidativoReproducción.Infertilidade masculinaEstresse oxidativoReprodução.The concept of infertility and its predisposing factors are still in the process of being discovered. Nowadays, it is known that most cases of infertility are linked to men and that their routine and life habits are relevant in this regard. The central one was oxidative stress, which stems from alcohol activities like other environmental consumption activities, directly affecting by interference, for example, in the production of spermatogenic substances and not environmentally suitable. After applying the selection criteria, 48 related to male infertility, triggers, among oxidative stress, as therapeutic mechanisms were analyzed, being articles developed for this, using SciELO and PubMed as tools. The influence of factors such as lifestyle, diet and obesity, in addition to the genetic factor, on the etiology of infertility was evidenced. Among the measures, curative measures on cells of genetic studies as well as in the field of natural medicine, still in development and sometimes ignored, together with antioxidant supplements are particularized. After a study of excellence for the construction of a project of better quality, it is necessary to develop a project of excellence of quality for family members, it is necessary to develop a project of excellence for family members in pairs, which offers an education work that is also in family quality studies, directly to employees due to their infertility condition. The present review aims to describe the main causes of male infertility, with emphasis on oxidative stress, as well as the interventions being developed and working on its treatment.El concepto de infertilidad y sus factores predisponentes aún están en proceso de ser descubiertos. Hoy en día se sabe que la mayoría de los casos de infertilidad están ligados a los hombres y que su rutina y hábitos de vida son relevantes en este sentido. El central fue el estrés oxidativo, que se deriva de las actividades del alcohol como otras actividades de consumo ambiental, afectando directamente por la interferencia, por ejemplo, en la producción de sustancias espermatogénicas y no ambientalmente adecuadas. Infertilidad masculina, desencadenantes, entre estrés oxidativo, como mecanismos terapéuticos siendo artículos desarrollados para ello, teniendo como herramientas SciELO y PubMed. Se evidenció la influencia de factores como el estilo de vida, la dieta y la obesidad, además del factor genético, en la etiología de la infertilidad. Entre las medidas, se particularizan medidas curativas sobre células de estudios genéticos así como en el campo de la medicina natural, aún en desarrollo y en ocasiones ignoradas, junto a suplementos antioxidantes. La construcción de un proyecto de mejor calidad, desarrollando un proyecto de excelente calidad para los familiares, desarrollando un proyecto de excelencia para los familiares y compañeros, ofreciendo un trabajo educativo que sea, también en estudios de calidad familiar, directamente a los empleados por la condición de infertilidad. La presente revisión tiene como objetivo describir las principales causas de la infertilidad masculina, con énfasis en el estrés oxidativo, así como las intervenciones que se están desarrollando y trabajando en su tratamiento.O conceito de infertilidade e seus fatores predisponentes estão ainda em processo de descobrimento. Nos dias atuais, sabe-se que a maior parte dos casos de infertilidade está ligado ao homem e que sua rotina e hábitos de vida tem relevante importância nesse aspecto. O enfoque central foi para o estresse oxidativo, que decorre de atividades como consumo de álcool, tabaco e outras exposições ambientais, afetando diretamente a fertilidade por interferir, por exemplo, na produção hormônios e no próprio processo de espermatogênese. Foram analisados, após aplicação dos critérios de seleção, 48 artigos relacionados à infertilidade masculina, seus desencadeantes, entre eles o estresse oxidativo, bem como mecanismos terapêuticos sendo desenvolvidos para tal, tendo como base as plataformas SciELO e PubMed. Foi evidenciada a influência de fatores como hábitos de vida, alimentação e obesidade, além do fator genético, na etiologia da infertilidade. Dentre as medidas curativas, particularizam-se discussões sobre os estudos genéticos em células tronco como também no âmbito da medicina natural, ainda em desenvolvimento e por vezes negligenciada, juntamente com suplementos antioxidantes. Após um maior conhecimento sobre a efetividade de tais intervenções, conclui-se a relevância e necessidade de investimentos em tais estratégias, visando uma melhor qualidade de vida aos casais que desejam constituir um núcleo familiar e também diretamente aos homens que são, não raramente, estigmatizados pela condição de infertilidade. A presente revisão tem por finalidade descrever as principais causas de infertilidade masculina, com ênfase no estresse oxidativo, bem como das intervenções sendo desenvolvidas e que apresentam eficácia no seu tratamento.Research, Society and Development2022-08-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3313910.33448/rsd-v11i10.33139Research, Society and Development; Vol. 11 No. 10; e405111033139Research, Society and Development; Vol. 11 Núm. 10; e405111033139Research, Society and Development; v. 11 n. 10; e4051110331392525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33139/27915Copyright (c) 2022 Tauana Caroline Marconato; Ricardo Ditzel Delle Donne; Renata Marino Romano; Marco Aurelio Romanohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarconato, Tauana Caroline Donne, Ricardo Ditzel DelleRomano, Renata Marino Romano, Marco Aurelio2022-08-12T22:23:03Zoai:ojs.pkp.sfu.ca:article/33139Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:48:53.127890Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Male infertility: main causes and emerging therapies, a review
Infertilidad masculina: causas principales y terapias emergentes, una revisión
Infertilidade masculina: principais causas e terapêuticas emergentes, uma revisão
title Male infertility: main causes and emerging therapies, a review
spellingShingle Male infertility: main causes and emerging therapies, a review
Marconato, Tauana Caroline
Male infertility
Oxidative stress
Reproduction.
Infertilidad masculina
Estrés oxidativo
Reproducción.
Infertilidade masculina
Estresse oxidativo
Reprodução.
title_short Male infertility: main causes and emerging therapies, a review
title_full Male infertility: main causes and emerging therapies, a review
title_fullStr Male infertility: main causes and emerging therapies, a review
title_full_unstemmed Male infertility: main causes and emerging therapies, a review
title_sort Male infertility: main causes and emerging therapies, a review
author Marconato, Tauana Caroline
author_facet Marconato, Tauana Caroline
Donne, Ricardo Ditzel Delle
Romano, Renata Marino
Romano, Marco Aurelio
author_role author
author2 Donne, Ricardo Ditzel Delle
Romano, Renata Marino
Romano, Marco Aurelio
author2_role author
author
author
dc.contributor.author.fl_str_mv Marconato, Tauana Caroline
Donne, Ricardo Ditzel Delle
Romano, Renata Marino
Romano, Marco Aurelio
dc.subject.por.fl_str_mv Male infertility
Oxidative stress
Reproduction.
Infertilidad masculina
Estrés oxidativo
Reproducción.
Infertilidade masculina
Estresse oxidativo
Reprodução.
topic Male infertility
Oxidative stress
Reproduction.
Infertilidad masculina
Estrés oxidativo
Reproducción.
Infertilidade masculina
Estresse oxidativo
Reprodução.
description The concept of infertility and its predisposing factors are still in the process of being discovered. Nowadays, it is known that most cases of infertility are linked to men and that their routine and life habits are relevant in this regard. The central one was oxidative stress, which stems from alcohol activities like other environmental consumption activities, directly affecting by interference, for example, in the production of spermatogenic substances and not environmentally suitable. After applying the selection criteria, 48 related to male infertility, triggers, among oxidative stress, as therapeutic mechanisms were analyzed, being articles developed for this, using SciELO and PubMed as tools. The influence of factors such as lifestyle, diet and obesity, in addition to the genetic factor, on the etiology of infertility was evidenced. Among the measures, curative measures on cells of genetic studies as well as in the field of natural medicine, still in development and sometimes ignored, together with antioxidant supplements are particularized. After a study of excellence for the construction of a project of better quality, it is necessary to develop a project of excellence of quality for family members, it is necessary to develop a project of excellence for family members in pairs, which offers an education work that is also in family quality studies, directly to employees due to their infertility condition. The present review aims to describe the main causes of male infertility, with emphasis on oxidative stress, as well as the interventions being developed and working on its treatment.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-05
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info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33139
10.33448/rsd-v11i10.33139
url https://rsdjournal.org/index.php/rsd/article/view/33139
identifier_str_mv 10.33448/rsd-v11i10.33139
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33139/27915
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 10; e405111033139
Research, Society and Development; Vol. 11 Núm. 10; e405111033139
Research, Society and Development; v. 11 n. 10; e405111033139
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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