Hypothalamic hamartoma: A rare case of central precocious puberty in males

Detalhes bibliográficos
Autor(a) principal: Almeida, Ana Cecília Borges
Data de Publicação: 2023
Outros Autores: Hernandes , Sandra Regina Chahuan Tobji
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/44626
Resumo: This study reported a rare case of central precocious puberty in a male child, who was 2 years and 4 months old, with a history of gelastic seizures and signs of precocious puberty. The patient, at 1 year and 8 months old, exhibited pubic hair growth, increased penile and testicular size, and the onset of acne. Additionally, the child experienced unprovoked bouts of laughter (gelastic seizures) and daily behavioral changes, including aggression. An MRI examination of the pituitary gland revealed an expansive lesion in the hypothalamic region with partial obliteration of the posterior aspect of the suprasellar cistern and interpeduncular cistern, consistent with hypothalamic hamartoma. Treatment was initiated with GnRH analog and carbamazepine. The patient described here continues to receive pharmacological treatment.
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spelling Hypothalamic hamartoma: A rare case of central precocious puberty in malesHamartoma hipotalámico: Un caso raro de pubertad precoz central en hombresHamartoma hipotalâmico: Um caso raro de puberdade precoce central no sexo masculino Puberdade precoce centralHarmatomaHipotálamo.Puberty precocious centralHamartomaHypothalamic.Pubertad precoz centralHamartomaHipotalámico.This study reported a rare case of central precocious puberty in a male child, who was 2 years and 4 months old, with a history of gelastic seizures and signs of precocious puberty. The patient, at 1 year and 8 months old, exhibited pubic hair growth, increased penile and testicular size, and the onset of acne. Additionally, the child experienced unprovoked bouts of laughter (gelastic seizures) and daily behavioral changes, including aggression. An MRI examination of the pituitary gland revealed an expansive lesion in the hypothalamic region with partial obliteration of the posterior aspect of the suprasellar cistern and interpeduncular cistern, consistent with hypothalamic hamartoma. Treatment was initiated with GnRH analog and carbamazepine. The patient described here continues to receive pharmacological treatment.El propósito de este trabajo fue reportar un caso raro de un niño, de poco más de 2 años, con antecedentes de convulsiones gelásticas y signos de pubertad precoz. La paciente, de 1 año y 8 meses, presentaba vello púbico, aumento de tamaño peneano y testicular y aparición de acné. Sumado a esto, el niño presentaba ataques de risa desmotivada (crisis gelásticas) y cambios de comportamiento, como agresividad en el día a día. En el examen de Imagen por Resonancia Magnética Nuclear de hipófisis se observó lesión expansiva en la región hipotalámica con obliteración parcial de la cara posterior de la cisterna supraselar y cisterna interpeduncular, compatible con hamartoma hipotalámico. Se inició tratamiento con análogo de GnRH y carbamazepina. El paciente aquí reportado aún se encuentra en tratamiento farmacológico.Este trabalho teve por propósito, relatar um caso raro de um menino, com pouco mais de 2 anos de idade, histórico de convulsões gelásticas e sinais de puberdade precoce. O paciente, com 1 ano e 8 meses de idade, apresentou pelos pubianos, aumento do tamanho peniano, testicular e surgimento de acnes. Somado a isto, a criança manifestava crises de risos desmotivados (convulsões gelásticas) e alteração comportamental, como agressividade diariamente.  No exame de Ressonância Nuclear Magnética da hipófise observou-se uma lesão expansiva em região hipotalâmica com parcial obliteração do aspecto posterior da cisterna suprasselar e cisterna interpeduncular, compatível com hamartoma hipotalâmico. Deu-se início ao tratamento, com o análogo do GnRH e carbamazepina. O paciente aqui relatado, segue em tratamento farmacológico.Research, Society and Development2023-12-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4462610.33448/rsd-v12i14.44626Research, Society and Development; Vol. 12 No. 14; e116121444626Research, Society and Development; Vol. 12 Núm. 14; e116121444626Research, Society and Development; v. 12 n. 14; e1161214446262525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/44626/35682Copyright (c) 2023 Ana Cecília Borges Almeida; Sandra Regina Chahuan Tobji Hernandes https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAlmeida, Ana Cecília Borges Hernandes , Sandra Regina Chahuan Tobji 2024-01-01T11:23:38Zoai:ojs.pkp.sfu.ca:article/44626Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-01T11:23:38Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Hypothalamic hamartoma: A rare case of central precocious puberty in males
Hamartoma hipotalámico: Un caso raro de pubertad precoz central en hombres
Hamartoma hipotalâmico: Um caso raro de puberdade precoce central no sexo masculino
title Hypothalamic hamartoma: A rare case of central precocious puberty in males
spellingShingle Hypothalamic hamartoma: A rare case of central precocious puberty in males
Almeida, Ana Cecília Borges
Puberdade precoce central
Harmatoma
Hipotálamo.
Puberty precocious central
Hamartoma
Hypothalamic.
Pubertad precoz central
Hamartoma
Hipotalámico.
title_short Hypothalamic hamartoma: A rare case of central precocious puberty in males
title_full Hypothalamic hamartoma: A rare case of central precocious puberty in males
title_fullStr Hypothalamic hamartoma: A rare case of central precocious puberty in males
title_full_unstemmed Hypothalamic hamartoma: A rare case of central precocious puberty in males
title_sort Hypothalamic hamartoma: A rare case of central precocious puberty in males
author Almeida, Ana Cecília Borges
author_facet Almeida, Ana Cecília Borges
Hernandes , Sandra Regina Chahuan Tobji
author_role author
author2 Hernandes , Sandra Regina Chahuan Tobji
author2_role author
dc.contributor.author.fl_str_mv Almeida, Ana Cecília Borges
Hernandes , Sandra Regina Chahuan Tobji
dc.subject.por.fl_str_mv Puberdade precoce central
Harmatoma
Hipotálamo.
Puberty precocious central
Hamartoma
Hypothalamic.
Pubertad precoz central
Hamartoma
Hipotalámico.
topic Puberdade precoce central
Harmatoma
Hipotálamo.
Puberty precocious central
Hamartoma
Hypothalamic.
Pubertad precoz central
Hamartoma
Hipotalámico.
description This study reported a rare case of central precocious puberty in a male child, who was 2 years and 4 months old, with a history of gelastic seizures and signs of precocious puberty. The patient, at 1 year and 8 months old, exhibited pubic hair growth, increased penile and testicular size, and the onset of acne. Additionally, the child experienced unprovoked bouts of laughter (gelastic seizures) and daily behavioral changes, including aggression. An MRI examination of the pituitary gland revealed an expansive lesion in the hypothalamic region with partial obliteration of the posterior aspect of the suprasellar cistern and interpeduncular cistern, consistent with hypothalamic hamartoma. Treatment was initiated with GnRH analog and carbamazepine. The patient described here continues to receive pharmacological treatment.
publishDate 2023
dc.date.none.fl_str_mv 2023-12-28
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/44626
10.33448/rsd-v12i14.44626
url https://rsdjournal.org/index.php/rsd/article/view/44626
identifier_str_mv 10.33448/rsd-v12i14.44626
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/44626/35682
dc.rights.driver.fl_str_mv Copyright (c) 2023 Ana Cecília Borges Almeida; Sandra Regina Chahuan Tobji Hernandes
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Ana Cecília Borges Almeida; Sandra Regina Chahuan Tobji Hernandes
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 12 No. 14; e116121444626
Research, Society and Development; Vol. 12 Núm. 14; e116121444626
Research, Society and Development; v. 12 n. 14; e116121444626
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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