Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials

Detalhes bibliográficos
Autor(a) principal: Pedroso, Adriana Giomo
Data de Publicação: 2022
Outros Autores: Furtado, Gisele Rosada Dônola, Barbosa, Kledson Lopes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33581
Resumo: Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Objective: to know and analyze the scientific evidence related to the treatment of patients with facial melasma treated with niacinamide.  Method: a literature review was performed based on a data search in BIREME, PubMed, SciELO and ScienceDirect. Articles indexed in these electronic journals were included in the time frame from 2011 to 2019. Results: Evidence analyzes revealed a major impact on the appearance of facial melasma after niacinamide treatment. Well, the studies (100%) concluded improvement of the spots with the treatment time, improving the appearance of the skin. Conclusion: Evidence shows that niacinamide has a lightening property in adult women with improvement of melanic hyperpigmentation caused by melasma. However, there is very little evidence published in the last decade using pure niacinamide for increased pigmentation in melasma.
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spelling Niacinamide for the treatment of melasma: an integrative review of randomized clinical trialsNiacinamida para el tratamiento del melasma: una revisión integradora de ensayos clínicos aleatoriosNiacinamida para o tratamento do Melasma: uma Revisão Integrativa de Ensaios Clínicos Randomizados MelasmaNiacinamideSkin pigmentationQuality of life.MelasmaNiacinamidaPigmentación de la pielCalidad de vida.MelasmaNiacinamidaPigmentação da peleQualidade de vida.Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Objective: to know and analyze the scientific evidence related to the treatment of patients with facial melasma treated with niacinamide.  Method: a literature review was performed based on a data search in BIREME, PubMed, SciELO and ScienceDirect. Articles indexed in these electronic journals were included in the time frame from 2011 to 2019. Results: Evidence analyzes revealed a major impact on the appearance of facial melasma after niacinamide treatment. Well, the studies (100%) concluded improvement of the spots with the treatment time, improving the appearance of the skin. Conclusion: Evidence shows that niacinamide has a lightening property in adult women with improvement of melanic hyperpigmentation caused by melasma. However, there is very little evidence published in the last decade using pure niacinamide for increased pigmentation in melasma.Introducción: El melasma es una hipermelanosis muy frecuente y de difícil tratamiento, ya que suele responder mal a las terapias, afectando negativamente la calidad de vida de los pacientes. Objetivo: conocer y analizar la evidencia científica relacionada con el tratamiento de pacientes con melasma facial tratados con niacinamida. Método: se realizó una revisión de la literatura a partir de una búsqueda de datos en BIREME, PubMed, SciELO y ScienceDirect. Los artículos indexados en estas revistas electrónicas se incluyeron en el período de 2011 a 2019. Resultados: los análisis de evidencia revelaron un impacto importante en la aparición del melasma facial después del tratamiento con niacinamida. Pues bien, los estudios (100%) concluyeron mejora de las manchas con el tiempo de tratamiento, mejorando el aspecto de la piel. Conclusiones: La evidencia muestra que la niacinamida tiene una propiedad aclarante en mujeres adultas con mejoría de la hiperpigmentación melánica causada por el melasma. Sin embargo, hay muy poca evidencia publicada en la última década sobre el uso de niacinamida pura para el aumento de la pigmentación en el melasma.Introdução: O melasma é uma hipermelanose bastante comum e de difícil tratamento porque geralmente responde mal as terapias, afetando negativamente a qualidade de vida dos pacientes. Objetivo: conhecer e analisar as evidências científicas relacionadas ao tratamento de pacientes com melasma facial tratados com niacinamida. Método: foi realizada uma revisão de literatura com base em uma busca de dados no BIREME, PubMed, SciELO e ScienceDirect. Os artigos indexados nesses periódicos eletrônicos foram incluídos no espaço temporal de 2011 até 2019. Resultados: As análises das evidências revelaram impacto importante na aparência do melasma facial após o tratamento com niacinamida. Pois, os estudos (100%) concluíram melhora das manchas com o tempo de tratamento, melhorando a aparência da pele. Conclusões: As evidências mostram que a niacinamida possui propriedade clareadora em mulheres adultas com melhora da hiperpigmentação melânica causada pelo melasma. No entando, há pouquíssimas evidências publicadas na última década com uso da niacinamida pura para pigmentação aumentada no melasma.Research, Society and Development2022-08-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3358110.33448/rsd-v11i11.33581Research, Society and Development; Vol. 11 No. 11; e198111133581Research, Society and Development; Vol. 11 Núm. 11; e198111133581Research, Society and Development; v. 11 n. 11; e1981111335812525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/33581/28343Copyright (c) 2022 Adriana Giomo Pedroso; Gisele Rosada Dônola Furtado; Kledson Lopes Barbosahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPedroso, Adriana Giomo Furtado, Gisele Rosada Dônola Barbosa, Kledson Lopes 2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33581Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:11.235602Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
Niacinamida para el tratamiento del melasma: una revisión integradora de ensayos clínicos aleatorios
Niacinamida para o tratamento do Melasma: uma Revisão Integrativa de Ensaios Clínicos Randomizados
title Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
spellingShingle Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
Pedroso, Adriana Giomo
Melasma
Niacinamide
Skin pigmentation
Quality of life.
Melasma
Niacinamida
Pigmentación de la piel
Calidad de vida.
Melasma
Niacinamida
Pigmentação da pele
Qualidade de vida.
title_short Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
title_full Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
title_fullStr Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
title_full_unstemmed Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
title_sort Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
author Pedroso, Adriana Giomo
author_facet Pedroso, Adriana Giomo
Furtado, Gisele Rosada Dônola
Barbosa, Kledson Lopes
author_role author
author2 Furtado, Gisele Rosada Dônola
Barbosa, Kledson Lopes
author2_role author
author
dc.contributor.author.fl_str_mv Pedroso, Adriana Giomo
Furtado, Gisele Rosada Dônola
Barbosa, Kledson Lopes
dc.subject.por.fl_str_mv Melasma
Niacinamide
Skin pigmentation
Quality of life.
Melasma
Niacinamida
Pigmentación de la piel
Calidad de vida.
Melasma
Niacinamida
Pigmentação da pele
Qualidade de vida.
topic Melasma
Niacinamide
Skin pigmentation
Quality of life.
Melasma
Niacinamida
Pigmentación de la piel
Calidad de vida.
Melasma
Niacinamida
Pigmentação da pele
Qualidade de vida.
description Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Objective: to know and analyze the scientific evidence related to the treatment of patients with facial melasma treated with niacinamide.  Method: a literature review was performed based on a data search in BIREME, PubMed, SciELO and ScienceDirect. Articles indexed in these electronic journals were included in the time frame from 2011 to 2019. Results: Evidence analyzes revealed a major impact on the appearance of facial melasma after niacinamide treatment. Well, the studies (100%) concluded improvement of the spots with the treatment time, improving the appearance of the skin. Conclusion: Evidence shows that niacinamide has a lightening property in adult women with improvement of melanic hyperpigmentation caused by melasma. However, there is very little evidence published in the last decade using pure niacinamide for increased pigmentation in melasma.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-20
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33581
10.33448/rsd-v11i11.33581
url https://rsdjournal.org/index.php/rsd/article/view/33581
identifier_str_mv 10.33448/rsd-v11i11.33581
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33581/28343
dc.rights.driver.fl_str_mv Copyright (c) 2022 Adriana Giomo Pedroso; Gisele Rosada Dônola Furtado; Kledson Lopes Barbosa
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Adriana Giomo Pedroso; Gisele Rosada Dônola Furtado; Kledson Lopes Barbosa
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 11; e198111133581
Research, Society and Development; Vol. 11 Núm. 11; e198111133581
Research, Society and Development; v. 11 n. 11; e198111133581
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052770686074880

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