Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/33581 |
Resumo: | Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Objective: to know and analyze the scientific evidence related to the treatment of patients with facial melasma treated with niacinamide. Method: a literature review was performed based on a data search in BIREME, PubMed, SciELO and ScienceDirect. Articles indexed in these electronic journals were included in the time frame from 2011 to 2019. Results: Evidence analyzes revealed a major impact on the appearance of facial melasma after niacinamide treatment. Well, the studies (100%) concluded improvement of the spots with the treatment time, improving the appearance of the skin. Conclusion: Evidence shows that niacinamide has a lightening property in adult women with improvement of melanic hyperpigmentation caused by melasma. However, there is very little evidence published in the last decade using pure niacinamide for increased pigmentation in melasma. |
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Niacinamide for the treatment of melasma: an integrative review of randomized clinical trialsNiacinamida para el tratamiento del melasma: una revisión integradora de ensayos clínicos aleatoriosNiacinamida para o tratamento do Melasma: uma Revisão Integrativa de Ensaios Clínicos Randomizados MelasmaNiacinamideSkin pigmentationQuality of life.MelasmaNiacinamidaPigmentación de la pielCalidad de vida.MelasmaNiacinamidaPigmentação da peleQualidade de vida.Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Objective: to know and analyze the scientific evidence related to the treatment of patients with facial melasma treated with niacinamide. Method: a literature review was performed based on a data search in BIREME, PubMed, SciELO and ScienceDirect. Articles indexed in these electronic journals were included in the time frame from 2011 to 2019. Results: Evidence analyzes revealed a major impact on the appearance of facial melasma after niacinamide treatment. Well, the studies (100%) concluded improvement of the spots with the treatment time, improving the appearance of the skin. Conclusion: Evidence shows that niacinamide has a lightening property in adult women with improvement of melanic hyperpigmentation caused by melasma. However, there is very little evidence published in the last decade using pure niacinamide for increased pigmentation in melasma.Introducción: El melasma es una hipermelanosis muy frecuente y de difícil tratamiento, ya que suele responder mal a las terapias, afectando negativamente la calidad de vida de los pacientes. Objetivo: conocer y analizar la evidencia científica relacionada con el tratamiento de pacientes con melasma facial tratados con niacinamida. Método: se realizó una revisión de la literatura a partir de una búsqueda de datos en BIREME, PubMed, SciELO y ScienceDirect. Los artículos indexados en estas revistas electrónicas se incluyeron en el período de 2011 a 2019. Resultados: los análisis de evidencia revelaron un impacto importante en la aparición del melasma facial después del tratamiento con niacinamida. Pues bien, los estudios (100%) concluyeron mejora de las manchas con el tiempo de tratamiento, mejorando el aspecto de la piel. Conclusiones: La evidencia muestra que la niacinamida tiene una propiedad aclarante en mujeres adultas con mejoría de la hiperpigmentación melánica causada por el melasma. Sin embargo, hay muy poca evidencia publicada en la última década sobre el uso de niacinamida pura para el aumento de la pigmentación en el melasma.Introdução: O melasma é uma hipermelanose bastante comum e de difícil tratamento porque geralmente responde mal as terapias, afetando negativamente a qualidade de vida dos pacientes. Objetivo: conhecer e analisar as evidências científicas relacionadas ao tratamento de pacientes com melasma facial tratados com niacinamida. Método: foi realizada uma revisão de literatura com base em uma busca de dados no BIREME, PubMed, SciELO e ScienceDirect. Os artigos indexados nesses periódicos eletrônicos foram incluídos no espaço temporal de 2011 até 2019. Resultados: As análises das evidências revelaram impacto importante na aparência do melasma facial após o tratamento com niacinamida. Pois, os estudos (100%) concluíram melhora das manchas com o tempo de tratamento, melhorando a aparência da pele. Conclusões: As evidências mostram que a niacinamida possui propriedade clareadora em mulheres adultas com melhora da hiperpigmentação melânica causada pelo melasma. No entando, há pouquíssimas evidências publicadas na última década com uso da niacinamida pura para pigmentação aumentada no melasma.Research, Society and Development2022-08-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3358110.33448/rsd-v11i11.33581Research, Society and Development; Vol. 11 No. 11; e198111133581Research, Society and Development; Vol. 11 Núm. 11; e198111133581Research, Society and Development; v. 11 n. 11; e1981111335812525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/33581/28343Copyright (c) 2022 Adriana Giomo Pedroso; Gisele Rosada Dônola Furtado; Kledson Lopes Barbosahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPedroso, Adriana Giomo Furtado, Gisele Rosada Dônola Barbosa, Kledson Lopes 2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33581Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:11.235602Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials Niacinamida para el tratamiento del melasma: una revisión integradora de ensayos clínicos aleatorios Niacinamida para o tratamento do Melasma: uma Revisão Integrativa de Ensaios Clínicos Randomizados |
title |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials |
spellingShingle |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials Pedroso, Adriana Giomo Melasma Niacinamide Skin pigmentation Quality of life. Melasma Niacinamida Pigmentación de la piel Calidad de vida. Melasma Niacinamida Pigmentação da pele Qualidade de vida. |
title_short |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials |
title_full |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials |
title_fullStr |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials |
title_full_unstemmed |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials |
title_sort |
Niacinamide for the treatment of melasma: an integrative review of randomized clinical trials |
author |
Pedroso, Adriana Giomo |
author_facet |
Pedroso, Adriana Giomo Furtado, Gisele Rosada Dônola Barbosa, Kledson Lopes |
author_role |
author |
author2 |
Furtado, Gisele Rosada Dônola Barbosa, Kledson Lopes |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Pedroso, Adriana Giomo Furtado, Gisele Rosada Dônola Barbosa, Kledson Lopes |
dc.subject.por.fl_str_mv |
Melasma Niacinamide Skin pigmentation Quality of life. Melasma Niacinamida Pigmentación de la piel Calidad de vida. Melasma Niacinamida Pigmentação da pele Qualidade de vida. |
topic |
Melasma Niacinamide Skin pigmentation Quality of life. Melasma Niacinamida Pigmentación de la piel Calidad de vida. Melasma Niacinamida Pigmentação da pele Qualidade de vida. |
description |
Introduction: Melasma is a very common and difficult to treat hypermelanosis because it usually responds poorly to therapies, negatively affecting the quality of life of patients. Objective: to know and analyze the scientific evidence related to the treatment of patients with facial melasma treated with niacinamide. Method: a literature review was performed based on a data search in BIREME, PubMed, SciELO and ScienceDirect. Articles indexed in these electronic journals were included in the time frame from 2011 to 2019. Results: Evidence analyzes revealed a major impact on the appearance of facial melasma after niacinamide treatment. Well, the studies (100%) concluded improvement of the spots with the treatment time, improving the appearance of the skin. Conclusion: Evidence shows that niacinamide has a lightening property in adult women with improvement of melanic hyperpigmentation caused by melasma. However, there is very little evidence published in the last decade using pure niacinamide for increased pigmentation in melasma. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-20 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/33581 10.33448/rsd-v11i11.33581 |
url |
https://rsdjournal.org/index.php/rsd/article/view/33581 |
identifier_str_mv |
10.33448/rsd-v11i11.33581 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/33581/28343 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Adriana Giomo Pedroso; Gisele Rosada Dônola Furtado; Kledson Lopes Barbosa https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Adriana Giomo Pedroso; Gisele Rosada Dônola Furtado; Kledson Lopes Barbosa https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 11; e198111133581 Research, Society and Development; Vol. 11 Núm. 11; e198111133581 Research, Society and Development; v. 11 n. 11; e198111133581 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052770686074880 |