New pharmacological treatments used in psoriasis: integrative review

Detalhes bibliográficos
Autor(a) principal: Rocha, Denise Melgueiro
Data de Publicação: 2021
Outros Autores: Rodrigues Junior, Omero Martins
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/22717
Resumo: Psoriasis is a chronic, non-communicable disease that can cause acute pain and disfigurement to the patient, with pharmacological therapy as a satisfactory alternative with the use of retinoids, immunosuppressants and immunobiologicals that provide a great impact on the quality of life of patients, who constantly seek better forms of therapies that demonstrate effective results in controlling the disease. Thus, the article sought to describe the new treatment approaches for psoriasis available in the pharmaceutical market. The research was characterized by being an integrative literature review with data collection in the Lilacs, Medline and Scielo databases, according to the inclusion and exclusion criteria, from a total of 197 articles, 16 were selected to compose the analysis. As a result, there was an application of systemic therapy, with a combination of phototherapy with methotrexate, acitretin, cyclosporine, and biological drugs such as ixequizumab, guselcumab, secukinumab, adalimumab, infliximab, in addition to those for their children. With the study, it is possible to identify which drugs can act in the treatment of psoriasis, such as naltrexone, rottlerin, in addition to the use of an aerosol of calcipotriol and betamethasone dipropionate, and therapy techniques with microinfusion and iontophoresis for the treatment. The possibilities for treating the disease are mainly in the use of drugs, for patients, the main barriers are accessibility, medication usage, and adverse effects that contribute to advances in the remission of the disease.
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spelling New pharmacological treatments used in psoriasis: integrative reviewNuevos tratamientos farmacológicos utilizados en la psoriasis: revisíon integradoraNovos tratamentos farmacológicos utilizados na psoríase: revisão integrativaPsoriasisTratamientoTerapia farmacológica.Terapia farmacológicaPsoríaseTratamentoTerapia farmacológicaTerapia farmacológica.PsoriasisTreatmentPharmacological therapy.Pharmacological therapyPsoriasis is a chronic, non-communicable disease that can cause acute pain and disfigurement to the patient, with pharmacological therapy as a satisfactory alternative with the use of retinoids, immunosuppressants and immunobiologicals that provide a great impact on the quality of life of patients, who constantly seek better forms of therapies that demonstrate effective results in controlling the disease. Thus, the article sought to describe the new treatment approaches for psoriasis available in the pharmaceutical market. The research was characterized by being an integrative literature review with data collection in the Lilacs, Medline and Scielo databases, according to the inclusion and exclusion criteria, from a total of 197 articles, 16 were selected to compose the analysis. As a result, there was an application of systemic therapy, with a combination of phototherapy with methotrexate, acitretin, cyclosporine, and biological drugs such as ixequizumab, guselcumab, secukinumab, adalimumab, infliximab, in addition to those for their children. With the study, it is possible to identify which drugs can act in the treatment of psoriasis, such as naltrexone, rottlerin, in addition to the use of an aerosol of calcipotriol and betamethasone dipropionate, and therapy techniques with microinfusion and iontophoresis for the treatment. The possibilities for treating the disease are mainly in the use of drugs, for patients, the main barriers are accessibility, medication usage, and adverse effects that contribute to advances in the remission of the disease.La psoriasis es una enfermedad crónica, no transmisible que puede ocasionar dolor agudo y desfiguración al paciente, con la terapia farmacológica como alternativa satisfactoria con el uso de retinoides, inmunosupresores e inmunobiológicos que brindan un gran impacto en la calidad de vida de los pacientes, quienes buscar constantemente mejores formas de terapias que demuestren resultados efectivos en el control de la enfermedad. Por lo tanto, el artículo buscaba describir los nuevos enfoques de tratamiento para la psoriasis disponibles en el mercado farmacéutico. La investigación se caracterizó por ser una revisión de la literatura integradora con recolección de datos en las bases de datos Lilacs, Medline y Scielo, según los criterios de inclusión y exclusión, de un total de 197 artículos, se seleccionaron 16 para componer el análisis. Como resultado, hubo una aplicación de terapia sistémica, con una combinación de fototerapia con metotrexato, acitretina, ciclosporina y fármacos biológicos como ixequizumab, guselcumab, secukinumab, adalimumab, infliximab, además de los de sus hijos. Con el estudio es posible identificar qué fármacos pueden actuar en el tratamiento de la psoriasis, como naltrexona, rottlerina, además del uso de un aerosol de calcipotriol y dipropionato de betametasona, y técnicas de terapia con microinfusión e iontoforesis para el tratamiento. Las posibilidades de tratamiento de la enfermedad están principalmente en el uso de medicamentos, para los pacientes las principales barreras son la accesibilidad, el uso de medicamentos y los efectos adversos que contribuyen a los avances en la remisión de la enfermedad.A psoríase é uma doença crônica não transmissível, que pode causar dor aguda e desfiguração ao paciente, tendo como alternativa satisfatória a terapia farmacológica com o uso de retinóides, imunossupressores e imunobiológicos que proporcionam grande impacto na qualidade de vida dos pacientes, que constantemente buscam melhores formas de terapias, que demonstrem resultados eficazes no controle da doença. Sendo assim o artigo buscou descrever as novas abordagens de tratamento para psoríase disponíveis no mercado farmacêutico. A pesquisa caracterizou-se por ser uma revisão integrativa de literatura com coleta de dados nas bases Lilacs, Medline e Scielo, conforme os critérios de inclusão e exclusão, do total de 197 artigos, 16 foram selecionados para compor a análise. Como resultados, constatou-se a aplicação de terapia sistêmica, com a combinação da fototerapia à medicamentos de metotrexato, acitretina, ciclosporina, e medicamentos biológicos como o ixequizumabe, guselcumabe, secuquinumabe, adalimumabe, infliximabe, além dos especializados para tratamentos tópicos. Com o estudo, pode-se identificar medicamentos que podem atuar no tratamento da psoríase como a naltrexona, rottlerin, além do uso de um aerossol de calcipotriol e dipropionato de betametasona, e técnicas de terapia com microinfusão e iontoforese para o tratamento. As possibilidades de tratamento da doença estão principalmente no uso de fármacos, para os pacientes as barreiras principais são a acessibilidade, o custo do medicamento, e os efeitos adversos que contribuem avanços na remissão da doença.Research, Society and Development2021-11-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2271710.33448/rsd-v10i15.22717Research, Society and Development; Vol. 10 No. 15; e312101522717Research, Society and Development; Vol. 10 Núm. 15; e312101522717Research, Society and Development; v. 10 n. 15; e3121015227172525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/22717/20099Copyright (c) 2021 Denise Melgueiro Rocha; Omero Martins Rodrigues Juniorhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRocha, Denise Melgueiro Rodrigues Junior, Omero Martins 2021-12-06T10:13:53Zoai:ojs.pkp.sfu.ca:article/22717Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:48.343645Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv New pharmacological treatments used in psoriasis: integrative review
Nuevos tratamientos farmacológicos utilizados en la psoriasis: revisíon integradora
Novos tratamentos farmacológicos utilizados na psoríase: revisão integrativa
title New pharmacological treatments used in psoriasis: integrative review
spellingShingle New pharmacological treatments used in psoriasis: integrative review
Rocha, Denise Melgueiro
Psoriasis
Tratamiento
Terapia farmacológica.
Terapia farmacológica
Psoríase
Tratamento
Terapia farmacológica
Terapia farmacológica.
Psoriasis
Treatment
Pharmacological therapy.
Pharmacological therapy
title_short New pharmacological treatments used in psoriasis: integrative review
title_full New pharmacological treatments used in psoriasis: integrative review
title_fullStr New pharmacological treatments used in psoriasis: integrative review
title_full_unstemmed New pharmacological treatments used in psoriasis: integrative review
title_sort New pharmacological treatments used in psoriasis: integrative review
author Rocha, Denise Melgueiro
author_facet Rocha, Denise Melgueiro
Rodrigues Junior, Omero Martins
author_role author
author2 Rodrigues Junior, Omero Martins
author2_role author
dc.contributor.author.fl_str_mv Rocha, Denise Melgueiro
Rodrigues Junior, Omero Martins
dc.subject.por.fl_str_mv Psoriasis
Tratamiento
Terapia farmacológica.
Terapia farmacológica
Psoríase
Tratamento
Terapia farmacológica
Terapia farmacológica.
Psoriasis
Treatment
Pharmacological therapy.
Pharmacological therapy
topic Psoriasis
Tratamiento
Terapia farmacológica.
Terapia farmacológica
Psoríase
Tratamento
Terapia farmacológica
Terapia farmacológica.
Psoriasis
Treatment
Pharmacological therapy.
Pharmacological therapy
description Psoriasis is a chronic, non-communicable disease that can cause acute pain and disfigurement to the patient, with pharmacological therapy as a satisfactory alternative with the use of retinoids, immunosuppressants and immunobiologicals that provide a great impact on the quality of life of patients, who constantly seek better forms of therapies that demonstrate effective results in controlling the disease. Thus, the article sought to describe the new treatment approaches for psoriasis available in the pharmaceutical market. The research was characterized by being an integrative literature review with data collection in the Lilacs, Medline and Scielo databases, according to the inclusion and exclusion criteria, from a total of 197 articles, 16 were selected to compose the analysis. As a result, there was an application of systemic therapy, with a combination of phototherapy with methotrexate, acitretin, cyclosporine, and biological drugs such as ixequizumab, guselcumab, secukinumab, adalimumab, infliximab, in addition to those for their children. With the study, it is possible to identify which drugs can act in the treatment of psoriasis, such as naltrexone, rottlerin, in addition to the use of an aerosol of calcipotriol and betamethasone dipropionate, and therapy techniques with microinfusion and iontophoresis for the treatment. The possibilities for treating the disease are mainly in the use of drugs, for patients, the main barriers are accessibility, medication usage, and adverse effects that contribute to advances in the remission of the disease.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/22717
10.33448/rsd-v10i15.22717
url https://rsdjournal.org/index.php/rsd/article/view/22717
identifier_str_mv 10.33448/rsd-v10i15.22717
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/22717/20099
dc.rights.driver.fl_str_mv Copyright (c) 2021 Denise Melgueiro Rocha; Omero Martins Rodrigues Junior
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Denise Melgueiro Rocha; Omero Martins Rodrigues Junior
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 15; e312101522717
Research, Society and Development; Vol. 10 Núm. 15; e312101522717
Research, Society and Development; v. 10 n. 15; e312101522717
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052758665199616

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