Chemical profile and larvicidal activity of essential oil obtained from the leaves of Plectranthus amboinicus (Lour.) Spreng

• Autor(a) principal: Pereira, Ana Patrícia Matos
• Data de Publicação: 2021
• Outros Autores: Martins, Thércia Gabrielle Teixeira, Arruda, Mariana Oliveira, Dias, Andressa Almeida Santana, Souto, Laiane Araujo da Silva, Araújo Neto, Ari Pereira de, Soares , Liane Batista da Cruz, Carvalho, Ana Maria Almeida Silva, Sousa, Ricardo Teixeira de, Conceição , Carlos Eduardo Pereira, Conceição , Francilidia Oliveira Vitorino de Assunção, Everton, Gustavo Oliveira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/13846
• topic: Óleos essenciais; Larvicida; Constituintes químicos.; Aceite esencial; Larvicidal; Compuestos químicos.; Essential oils; Larvicide; Chemical constituents.

This study aimed to determine the chemical constituents and larvicidal activity of the essential oil of Plectranthus amboinicus (Lour.) Spreng against larvae of the Aedes aegypti mosquito. The essential oil (EO) was extracted by hydrodistillation at 100 ° C for 3 hours. The chemical composition was obtained by Gas Chromatography coupled to Mass Spectrometry (GC / MS). To assess larvicidal activity, Aedes aegypti larvae were subjected to EO solutions in concentrations of 10-100 mg L-1, where larval mortality was assessed and the LC50 was determined using the Probit method. The main chemical constituent found in the EO was carvacrol, which is considered to be very promising for pharmaceutical synthesis. The EO showed larvicidal activity with an LC50 of 28.52 mg L-1. According to the results found, it was possible to evaluate that the analyzed EO is composed of substances that have an efficient larvicidal effect against Aedes aegypti, thus encouraging its potential for application.