Scientific and technological prospecting of quercetin: use of Malpighia L. (acerola) species as a potential for the treatment of COVID-19

• Autor(a) principal: Macêdo, Maria do Amparo de Moura
• Data de Publicação: 2022
• Outros Autores: Souza, Ruanna Thaimires Brandão, Costa, Davi Nascimento, Santos , Juelina Oliveira dos, Reis, Renata Brito dos, Silva, Luana Leite da, Andrade, Ivanilza Moreira de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/24715
• topic: Acerola; Antiviral; Farmacologia.; Acerola; Antivírico; Farmacología.; Acerola; Antiviral; Pharmacology.

Quercetin is a flavonoid present in many vegetables, such as Malpighia L. (acerola), and has shown many pharmacological activities, including the antiviral and anti-inflammatory potential used in the treatment of various viruses, such as COVID-19, highlighting its economic and medicinal importance. The objective is to carry out a scientific and technological survey of the flavonoid quercetin found in acerola, in order to highlight the number of publications and patents filed in international databases and to highlight the pharmacological properties and effectiveness of these compounds in the treatment of COVID-19. Scientific and technological research was carried out in databases of articles and international patents on acerola, quercetin and COVID-19. The country with the highest number of publications was China (n=25), and publications began in 1967, with greater distribution in the areas of medicine and dentistry (n=78). While for technological prospecting, it was observed that Japan (n=367) had more patents filed and filings began in 2014, with A61K standing out as the most frequent CIP, related to health. Brazil did not stand out in this survey, as technological demand has not been stimulated, which demonstrates concern for the country.