Use of vasoactive drugs in the management of shock: a literature review

Detalhes bibliográficos
Autor(a) principal: Costa Junior, Valmir Alves da
Data de Publicação: 2022
Outros Autores: Branco, André Lages Gonçalves Castelo, Cavalcanti, André Luis Mendes, Barros, Beatriz Silva, Mapurunga Vasconcelos, Dara, Negreiros, Fernanda da Silva, Rosa, Ícaro Faustino, Portela, Letícia Pereira, Teixeira, Luana Nascimento Alencar
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/32453
Resumo: Acute diseases are often characterized by alterations in cardiovascular homeostasis. Underlying mechanisms may include multiple factors that alter blood volume (actual or effective), cardiac function (diastolic and/or systolic), or vessels (large vessels and/or microvasculature). The present study aims to analyze which vasoactive drugs are used in the management of shock. This is a study with a qualitative approach, where the integrative literature review was adopted, which according to Galvão (2012), is a construction of a broad analysis of the literature with pre-defined steps. Conducted through the Virtual Health Library (BVS) in the Pubmed databases, using the crossings of the English descriptors “Vasoactive Drug”, “Catecholamines”. Vasoactive agents are classified into sympathomimetics, vasopressin analogues and angiotensin II. Catecholamines are subdivided into indirect-acting, mixed-acting, and direct-acting categories. Only direct action agents have a role in the shock. Direct agents are further delineated by their selective nature (eg, dobutamine, phenylephrine) or non-selective activity (eg, epinephrine, norepinephrine) at α1, α2, β1, β2, and β3 receptors. Catecholamines are most often associated with clinical improvement in shock states. Vasoactive drugs are part of the treatment of shock and must be chosen according to the patient's need, so it is essential that health professionals have adequate knowledge of these drugs to better serve each case.
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spelling Use of vasoactive drugs in the management of shock: a literature reviewUso de fármacos vasoactivos en el manejo del shock: una revisión de la literaturaUso de drogas vasoativas no manejo do choque: uma revisão da literaturaChoqueDrogas vasoativasdrogas vasoativasManejo.manejoShockvasoactive drugsVasoactive drugsmanagementManagement.ShockFármacos vasoactivosmanejoManejo.Acute diseases are often characterized by alterations in cardiovascular homeostasis. Underlying mechanisms may include multiple factors that alter blood volume (actual or effective), cardiac function (diastolic and/or systolic), or vessels (large vessels and/or microvasculature). The present study aims to analyze which vasoactive drugs are used in the management of shock. This is a study with a qualitative approach, where the integrative literature review was adopted, which according to Galvão (2012), is a construction of a broad analysis of the literature with pre-defined steps. Conducted through the Virtual Health Library (BVS) in the Pubmed databases, using the crossings of the English descriptors “Vasoactive Drug”, “Catecholamines”. Vasoactive agents are classified into sympathomimetics, vasopressin analogues and angiotensin II. Catecholamines are subdivided into indirect-acting, mixed-acting, and direct-acting categories. Only direct action agents have a role in the shock. Direct agents are further delineated by their selective nature (eg, dobutamine, phenylephrine) or non-selective activity (eg, epinephrine, norepinephrine) at α1, α2, β1, β2, and β3 receptors. Catecholamines are most often associated with clinical improvement in shock states. Vasoactive drugs are part of the treatment of shock and must be chosen according to the patient's need, so it is essential that health professionals have adequate knowledge of these drugs to better serve each case.Las enfermedades agudas a menudo se caracterizan por alteraciones en la homeostasis cardiovascular. Los mecanismos subyacentes pueden incluir múltiples factores que alteran el volumen sanguíneo (real o efectivo), la función cardíaca (diastólica y/o sistólica) o los vasos (grandes vasos y/o microvasculatura). El presente estudio tiene como objetivo analizar qué fármacos vasoactivos se utilizan en el manejo del shock. Se trata de un estudio con abordaje cualitativo, donde se adoptó la revisión integrativa de la literatura, que según Galvão (2012), es una construcción de un amplio análisis de la literatura con pasos predefinidos. Realizado a través de la Biblioteca Virtual en Salud (BVS) en las bases de datos Pubmed, utilizando los cruces de los descriptores en inglés “Vasoactive Drug”, “Catecholamines”. Los agentes vasoactivos se clasifican en simpaticomiméticos, análogos de vasopresina y angiotensina II. Las catecolaminas se subdividen en categorías de acción indirecta, acción mixta y acción directa. Sólo los agentes de acción directa tienen un papel en el choque. Los agentes directos se definen además por su naturaleza selectiva (p. ej., dobutamina, fenilefrina) o actividad no selectiva (p. ej., epinefrina, norepinefrina) en los receptores α1, α2, β1, β2 y β3. Las catecolaminas se asocian con mayor frecuencia con la mejoría clínica en estados de shock. Los fármacos vasoactivos forman parte del tratamiento del shock y deben elegirse según la necesidad del paciente, por lo que es fundamental que los profesionales sanitarios tengan un conocimiento adecuado de estos fármacos para atender mejor cada caso.As doenças agudas são frequentemente caracterizadas por alteração na homeostase cardiovascular. Os mecanismos subjacentes podem incluir múltiplos fatores que alteram o volume sanguíneo (real ou efetivo), a função cardíaca (diastólica e/ou sistólica) ou os vasos (grandes vasos e/ou microvasculatura). O presente estudo tem como objetivo analisar quais são as drogas vasoativas são utilizadas no manejo do choque. Trata-se de um estudo de abordagem qualitativa, onde se adotou a revisão integrativa da literatura, que conforme Galvão (2012), é uma construção de uma análise ampla da literatura com passos pré-definidos. Realizado através da Biblioteca Virtual de Saúde (BVS) nas bases de dados do Pubmed, usando os cruzamentos dos descritores em inglês “Vasoactive Drug”, “Catecholamines”. Os agentes vasoativos são classificados em simpaticomiméticos, análogos da vasopressina e angiotensina II. As catecolaminas são subdivididas em categorias de ação indireta, ação mista e ação direta. Apenas os agentes de ação direta têm um papel no choque. Os agentes diretos são ainda delineados por sua natureza seletiva (por exemplo, dobutamina, fenilefrina) ou atividade não seletiva (por exemplo, epinefrina, norepinefrina) nos receptores α1, α2, β1, β2 e β3. As catecolaminas são mais frequentemente associadas à melhora clínica em estados de choque. As drogas vasoativas fazem parte do tratamento do choque e devem ser escolhidas de acordo com a necessidade do paciente, por isso é essencial que os profissionais de saúde tenham o conhecimento adequado desses fármacos para melhor atenderem cada caso.Research, Society and Development2022-07-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3245310.33448/rsd-v11i10.32453Research, Society and Development; Vol. 11 No. 10; e149111032453Research, Society and Development; Vol. 11 Núm. 10; e149111032453Research, Society and Development; v. 11 n. 10; e1491110324532525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/32453/27636Copyright (c) 2022 Valmir Alves da Costa Junior; André Lages Gonçalves Castelo Branco; André Luis Mendes Cavalcanti; Beatriz Silva Barros; Dara Mapurunga Vasconcelos; Fernanda da Silva Negreiros; Ícaro Faustino Rosa; Letícia Pereira Portela; Luana Nascimento Alencar Teixeirahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCosta Junior, Valmir Alves daBranco, André Lages Gonçalves Castelo Cavalcanti, André Luis Mendes Barros, Beatriz Silva Mapurunga Vasconcelos, DaraNegreiros, Fernanda da Silva Rosa, Ícaro Faustino Portela, Letícia Pereira Teixeira, Luana Nascimento Alencar 2022-08-12T22:23:03Zoai:ojs.pkp.sfu.ca:article/32453Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:48:27.838059Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Use of vasoactive drugs in the management of shock: a literature review
Uso de fármacos vasoactivos en el manejo del shock: una revisión de la literatura
Uso de drogas vasoativas no manejo do choque: uma revisão da literatura
title Use of vasoactive drugs in the management of shock: a literature review
spellingShingle Use of vasoactive drugs in the management of shock: a literature review
Costa Junior, Valmir Alves da
Choque
Drogas vasoativas
drogas vasoativas
Manejo.
manejo
Shock
vasoactive drugs
Vasoactive drugs
management
Management.
Shock
Fármacos vasoactivos
manejo
Manejo.
title_short Use of vasoactive drugs in the management of shock: a literature review
title_full Use of vasoactive drugs in the management of shock: a literature review
title_fullStr Use of vasoactive drugs in the management of shock: a literature review
title_full_unstemmed Use of vasoactive drugs in the management of shock: a literature review
title_sort Use of vasoactive drugs in the management of shock: a literature review
author Costa Junior, Valmir Alves da
author_facet Costa Junior, Valmir Alves da
Branco, André Lages Gonçalves Castelo
Cavalcanti, André Luis Mendes
Barros, Beatriz Silva
Mapurunga Vasconcelos, Dara
Negreiros, Fernanda da Silva
Rosa, Ícaro Faustino
Portela, Letícia Pereira
Teixeira, Luana Nascimento Alencar
author_role author
author2 Branco, André Lages Gonçalves Castelo
Cavalcanti, André Luis Mendes
Barros, Beatriz Silva
Mapurunga Vasconcelos, Dara
Negreiros, Fernanda da Silva
Rosa, Ícaro Faustino
Portela, Letícia Pereira
Teixeira, Luana Nascimento Alencar
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Costa Junior, Valmir Alves da
Branco, André Lages Gonçalves Castelo
Cavalcanti, André Luis Mendes
Barros, Beatriz Silva
Mapurunga Vasconcelos, Dara
Negreiros, Fernanda da Silva
Rosa, Ícaro Faustino
Portela, Letícia Pereira
Teixeira, Luana Nascimento Alencar
dc.subject.por.fl_str_mv Choque
Drogas vasoativas
drogas vasoativas
Manejo.
manejo
Shock
vasoactive drugs
Vasoactive drugs
management
Management.
Shock
Fármacos vasoactivos
manejo
Manejo.
topic Choque
Drogas vasoativas
drogas vasoativas
Manejo.
manejo
Shock
vasoactive drugs
Vasoactive drugs
management
Management.
Shock
Fármacos vasoactivos
manejo
Manejo.
description Acute diseases are often characterized by alterations in cardiovascular homeostasis. Underlying mechanisms may include multiple factors that alter blood volume (actual or effective), cardiac function (diastolic and/or systolic), or vessels (large vessels and/or microvasculature). The present study aims to analyze which vasoactive drugs are used in the management of shock. This is a study with a qualitative approach, where the integrative literature review was adopted, which according to Galvão (2012), is a construction of a broad analysis of the literature with pre-defined steps. Conducted through the Virtual Health Library (BVS) in the Pubmed databases, using the crossings of the English descriptors “Vasoactive Drug”, “Catecholamines”. Vasoactive agents are classified into sympathomimetics, vasopressin analogues and angiotensin II. Catecholamines are subdivided into indirect-acting, mixed-acting, and direct-acting categories. Only direct action agents have a role in the shock. Direct agents are further delineated by their selective nature (eg, dobutamine, phenylephrine) or non-selective activity (eg, epinephrine, norepinephrine) at α1, α2, β1, β2, and β3 receptors. Catecholamines are most often associated with clinical improvement in shock states. Vasoactive drugs are part of the treatment of shock and must be chosen according to the patient's need, so it is essential that health professionals have adequate knowledge of these drugs to better serve each case.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-26
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/32453
10.33448/rsd-v11i10.32453
url https://rsdjournal.org/index.php/rsd/article/view/32453
identifier_str_mv 10.33448/rsd-v11i10.32453
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/32453/27636
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 10; e149111032453
Research, Society and Development; Vol. 11 Núm. 10; e149111032453
Research, Society and Development; v. 11 n. 10; e149111032453
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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