Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review

Detalhes bibliográficos
Autor(a) principal: Sousa, Alécio Henrique da Silva
Data de Publicação: 2021
Outros Autores: Martins, Stanley Bastos, Cortez, Antonio Carlos Leal
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/24678
Resumo: Objective: To elucidate, through a integrative review, scientific evidence about the influence of comorbidities on the health of the elderly against the pandemic of COVID-19. Methods: This is a integrative literature review study, conducted in the VHL database through the controlled descriptors elderly, comorbidity and COVID-19, as well as its translations into Spanish and English, according to the DeCS and Mesh, published between the years 2020 and May 2021. Results: A total of 12 comorbidities associated with COVID-19 infection in the elderly were identified in the studies selected in this review. Cardiovascular disease was the main one, accounting for 72.72%, followed by diabetes (72.72%), hypertension (63.63%), chronic kidney disease and obesity with 27.27%, dementia and chronic obstructive pulmonary disease with 22.72%, cancer (18.18%), liver disease (9.09%), asthma, dyslipidemia, and depression with 4.54%. Final Considerations: It can be concluded that the main comorbidities observed in the health of the elderly in the face of the COVID-19 pandemic are associated with a significant increase in the risk of hospitalization and a high mortality rate in this population. The real reason why SARS-CoV-2 infections are more severe and fatal in the elderly is not yet well elucidated, viable hypotheses are emerging and encompass more than comorbidities, including immune repertoire, inflammasome activity, genetic and epigenetic influences.
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spelling Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative reviewInfluencia de las comorbilidades en la salud de los ancianos ante la pandemia de Covid-19: una revisión integradoraInfluência das comorbidades na saúde dos idosos frente à pandemia da Covid-19: uma revisão integrativaIdosoComorbidadesSaúdeCOVID-19.AncianosComorbilidadesSaludCOVID-19.ElderlyComorbiditiesHealthCOVID-19.Objective: To elucidate, through a integrative review, scientific evidence about the influence of comorbidities on the health of the elderly against the pandemic of COVID-19. Methods: This is a integrative literature review study, conducted in the VHL database through the controlled descriptors elderly, comorbidity and COVID-19, as well as its translations into Spanish and English, according to the DeCS and Mesh, published between the years 2020 and May 2021. Results: A total of 12 comorbidities associated with COVID-19 infection in the elderly were identified in the studies selected in this review. Cardiovascular disease was the main one, accounting for 72.72%, followed by diabetes (72.72%), hypertension (63.63%), chronic kidney disease and obesity with 27.27%, dementia and chronic obstructive pulmonary disease with 22.72%, cancer (18.18%), liver disease (9.09%), asthma, dyslipidemia, and depression with 4.54%. Final Considerations: It can be concluded that the main comorbidities observed in the health of the elderly in the face of the COVID-19 pandemic are associated with a significant increase in the risk of hospitalization and a high mortality rate in this population. The real reason why SARS-CoV-2 infections are more severe and fatal in the elderly is not yet well elucidated, viable hypotheses are emerging and encompass more than comorbidities, including immune repertoire, inflammasome activity, genetic and epigenetic influences.Objetivo: dilucidar, a través de una revisión integradora, la evidencia científica sobre la influencia de las comorbilidades en la salud de las personas mayores ante la pandemia COVID-19. Métodos: se trata de una revisión integradora de la literatura, realizado en base a los datos BVS a través de los descritores controlados idos, comorbilidad y COVID-19, así como sus traducciones al español e inglés, de acuerdo con los DeCS y Mesh, publicados entre los años 2020 y mayo de 2021. Resultados: Se identificaron un total de 12 comorbilidades asociadas a la infección por COVID-19 en los individuos, en los estudios seleccionados en esta revisión. Siendo las principales constituidas por las enfermedades cardiovasculares, que correspondieron al 72,72%, seguidas de la diabetes (72,72%), la hipertensión (63,63%), la enfermedad renal crónica y la obesidad con el 27,27%, la demencia y la enfermedad pulmonar obstructiva crónica con el 22,72%, el cáncer (18,18%), la enfermedad hepática (9,09%), el asma, las dislipidemias y la depresión con el 4,54%. Consideraciones finales: Se puede concluir que las principales comorbilidades observadas en la salud de los ancianos frente a la pandemia del COVID-19 se asocian a un aumento significativo del riesgo de hospitalización y a una elevada mortalidad en esta población. La verdadera razón por la que las infecciones por SARS-CoV-2 son más graves y mortales en los ancianos aún no está bien dilucidada, pero están surgiendo hipótesis viables que abarcan más que las comorbilidades, incluyendo el repertorio inmunitario, la actividad del inflamasoma y las influencias genéticas y epigenéticas.Objetivo: elucidar, através de uma revisão integrativa, evidências científicas acerca da influência das comorbidades na saúde dos idosos frente à pandemia da COVID-19. Métodos: trata-se de um estudo de revisão integrativa da literatura, realizada na base de dados BVS através dos descritores controlados idoso, comorbidade e COVID-19, bem como suas traduções para o espanhol e inglês, de acordo com os DeCS e Mesh, publicados entre os anos de 2020 a maio de 2021. Resultados: Identificaram-se um total de 12 comorbidades associadas à infecção por COVID-19 em idosos nos estudos selecionados nessa revisão. Sendo a principal constituída pelas doenças cardiovasculares, que corresponderam a 72,72%, seguida pela diabetes (72,72%), hipertensão (63,63%), doença renal crônica e obesidade com 27,27%, demência e doença pulmonar obstrutiva crônica com 22,72%, câncer (18,18%), doença hepática (9,09%), asma, dislipidemias e depressão com 4,54%. Considerações Finais: Pode-se concluir que as principais comorbidades observadas na saúde dos idosos frente à pandemia da COVID-19 estão associadas a um aumento significativo do risco de hospitalização e alto índice de mortalidade nessa população. O real motivo que leva as infecções pelo SARS-CoV-2 serem mais graves e fatais no idoso ainda não é bem elucidado, as hipóteses viáveis são emergentes e abrangem mais do que as comorbidades, incluindo repertório imunológico, atividade de inflamassomas, influências genéticas e epigenéticas.Research, Society and Development2021-12-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2467810.33448/rsd-v10i17.24678Research, Society and Development; Vol. 10 No. 17; e199101724678Research, Society and Development; Vol. 10 Núm. 17; e199101724678Research, Society and Development; v. 10 n. 17; e1991017246782525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/24678/21489Copyright (c) 2021 Alécio Henrique da Silva Sousa; Stanley Bastos Martins; Antonio Carlos Leal Cortezhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSousa, Alécio Henrique da Silva Martins, Stanley BastosCortez, Antonio Carlos Leal 2022-01-01T11:11:08Zoai:ojs.pkp.sfu.ca:article/24678Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:43:09.338813Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
Influencia de las comorbilidades en la salud de los ancianos ante la pandemia de Covid-19: una revisión integradora
Influência das comorbidades na saúde dos idosos frente à pandemia da Covid-19: uma revisão integrativa
title Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
spellingShingle Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
Sousa, Alécio Henrique da Silva
Idoso
Comorbidades
Saúde
COVID-19.
Ancianos
Comorbilidades
Salud
COVID-19.
Elderly
Comorbidities
Health
COVID-19.
title_short Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
title_full Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
title_fullStr Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
title_full_unstemmed Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
title_sort Influence of comorbidities on the health of the elderly in the face of the Covid-19 pandemic: a integrative review
author Sousa, Alécio Henrique da Silva
author_facet Sousa, Alécio Henrique da Silva
Martins, Stanley Bastos
Cortez, Antonio Carlos Leal
author_role author
author2 Martins, Stanley Bastos
Cortez, Antonio Carlos Leal
author2_role author
author
dc.contributor.author.fl_str_mv Sousa, Alécio Henrique da Silva
Martins, Stanley Bastos
Cortez, Antonio Carlos Leal
dc.subject.por.fl_str_mv Idoso
Comorbidades
Saúde
COVID-19.
Ancianos
Comorbilidades
Salud
COVID-19.
Elderly
Comorbidities
Health
COVID-19.
topic Idoso
Comorbidades
Saúde
COVID-19.
Ancianos
Comorbilidades
Salud
COVID-19.
Elderly
Comorbidities
Health
COVID-19.
description Objective: To elucidate, through a integrative review, scientific evidence about the influence of comorbidities on the health of the elderly against the pandemic of COVID-19. Methods: This is a integrative literature review study, conducted in the VHL database through the controlled descriptors elderly, comorbidity and COVID-19, as well as its translations into Spanish and English, according to the DeCS and Mesh, published between the years 2020 and May 2021. Results: A total of 12 comorbidities associated with COVID-19 infection in the elderly were identified in the studies selected in this review. Cardiovascular disease was the main one, accounting for 72.72%, followed by diabetes (72.72%), hypertension (63.63%), chronic kidney disease and obesity with 27.27%, dementia and chronic obstructive pulmonary disease with 22.72%, cancer (18.18%), liver disease (9.09%), asthma, dyslipidemia, and depression with 4.54%. Final Considerations: It can be concluded that the main comorbidities observed in the health of the elderly in the face of the COVID-19 pandemic are associated with a significant increase in the risk of hospitalization and a high mortality rate in this population. The real reason why SARS-CoV-2 infections are more severe and fatal in the elderly is not yet well elucidated, viable hypotheses are emerging and encompass more than comorbidities, including immune repertoire, inflammasome activity, genetic and epigenetic influences.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-24
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/24678
10.33448/rsd-v10i17.24678
url https://rsdjournal.org/index.php/rsd/article/view/24678
identifier_str_mv 10.33448/rsd-v10i17.24678
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/24678/21489
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 17; e199101724678
Research, Society and Development; Vol. 10 Núm. 17; e199101724678
Research, Society and Development; v. 10 n. 17; e199101724678
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052791798104064

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