Phytochemical Screening of propolis samples from Northeast Brazil by HPLC: Green, black and red varieties

• Autor(a) principal: Rodrigues , Maria do Socorro Araujo
• Data de Publicação: 2020
• Outros Autores: Sousa , Bruna Rodrigues de, Cunha, Marcelo Holanda da, Araujo, Alfredina dos Santos, Silva, Osvaldo Soares da, Fonseca, Sthelio Braga da, Meireles, Bruno Raniere Lins de Albuquerque, Medeiros, Weverton Pereira de, Freitas, Francisco Bruno Ferreira de, Albuquerque, Tiago da Nóbrega
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/8936
• topic: Atividade antioxidante; Perfil quantitativo; CLAE.; Actividad de antioxidante; Perfil cuantitativo; CLAE.; Antioxidant activity; Quantitative profile; HPLC.

Propolis is a natural resin made by bees of the genus Apis sp., And because of its antioxidant and antimicrobial activity, it has been used frequently in alternative medicine in several places of the world. These biological characteristics are related to their chemical composition, precisely to the phenolic compounds that vary in relation to their structure and concentration depending on the region of production, availability of plant sources for resin collection and time of year. Several experiments have been conducted in order to define the compounds that characterize these activities. The aim of this study was to elaborate and identify the chemical composition of the hydroalcoholic extracts of red, green and black propolis by High Performance Liquid Chromatography. The profiles presented by High Efficiency Liquid Chromatography (HPLC) of the extracts of the green, red and black propolis samples were very similar, but there was a great variation in terms of quantitative profile, besides playing an essential role in the antioxidant activity. Through the chromatograms, it is verified that as a function of the concentration of propolis, different phenolic compounds are extracted from the propolis, resulting in extracts with different biological properties. These data contribute to the knowledge of the biological activity of the hydroalcoholic extract of green propolis, favoring the search for new therapeutic agents.